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| Patent # | Description |
|---|---|
| 2018/0085398 |
COMPOSITIONS AND METHODS OF TREATING CANCER The present invention provides compositions and methods for treating cancer. |
| 2018/0085397 |
One day burns treatment discovery for an industrial material The grease (Machines lubricant), as burns medicine (treatment for burns), which is consisting of: 70-95% Base oil, 3-30% Thickner, F0-10% Additives, which is... |
| 2018/0085396 |
INHERENTLY RADIOPAQUE POLYMERIC PRODUCTS FOR EMBOLOTHERAPY Preferred embodiments relate to compositions of inherently radiopaque, biocompatible, bioresorbable polymeric particles and methods of using them for... |
| 2018/0085395 |
POLYION COMPLEX OF POLY(L-ARGININE) SEGMENT-CONTAINING BLOCK COPOLYMER AND
POLYANIONIC POLYMER An object of the present invention is to provide a composition that serves as an efficient arginine substrate for inducible NO synthase (iNOS) in tumor. The... |
| 2018/0085394 |
LOCAL APPLICATION OF D-LACTIC ACID DIMER IS SELECTIVELY CYTOTOXIC WHEN
APPLIED TO CANCER CELLS At equimolar concentrations, D-lactic acid dimer is more cytotoxic than L-lactic acid when directly applied to human HeLa cells in culture. The cytotoxicity of... |
| 2018/0085393 |
COMPOSITIONS FOR SENSITIVE SKIN Disclosed are compositions and methods for their use that include a combination of hydrolyzed algin, escin, Ruscus aculeatus root extract, ammonium... |
| 2018/0085392 |
CYCLODEXTRIN COMPOUNDS FOR THE PREVENTION AND TREATMENT OF AGING Cyclodextrin compound therapeutics to reduce age-related non-bisretinoid lipofuscin in a patient having a buildup of same, said method comprising administering... |
| 2018/0085391 |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF OPHTHALMIC DISEASES AND
CONDITIONS The present invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides in the treatment, prevention... |
| 2018/0085390 |
Polyvalent RNA-Nanoparticle Compositions The present invention concerns nanoparticles functionalized with duplex RNA for a variety of uses, including but not limited to gene regulation. More... |
| 2018/0085389 |
AGENTS AND METHODS FOR TREATING PANCREATIC DUCTAL ADENOCARCINOMAS It has been discovered that NAD+-dependent histone deacetylase SIRT6 is critical for suppression of PDAC by con trolling the expression of Lin28b, which is a... |
| 2018/0085388 |
DELIVERY OF RNA TO TRIGGER MULTIPLE IMMUNE PATHWAYS RNA encoding an immunogen is co-delivered to non-immune cells at the site of delivery and also to immune cells which infiltrate the site of delivery. The... |
| 2018/0085387 |
THERAPEUTIC COMPOSITIONS FOR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS Pharmaceutical formulations suitable for treating viral infections such as HIV are provided, in particular solid oral dosage forms including the compounds of... |
| 2018/0085386 |
URIDINE MONOPHOSPHATE AND TRIPHOSPHATE DERIVATIVES, COMPOSITIONS AND
METHODS OF USE This disclosure relates to uridine nucleoside derivatives, compositions comprising therapeutically effective amounts of those nucleoside derivatives and... |
| 2018/0085385 |
GLUCOSE-SENSITIVE CELL PROTECTING AGENT The invention provides an agent containing N-acetyl-D-mannosamine for protecting a glucose-sensitive cell from glucose toxicity due to high glucose... |
| 2018/0085384 |
NUTRITIONAL COMPOSITIONS AND INFANT FORMULAS CONTAINING OLIGOFRUCTOSE FOR
REDUCING THE LOAD OF PATHOGENIC... The invention relates to a nutrition composition with oligofructose and optionally high sn-2 palmitate for down regulating, decreasing or inhibiting the growth... |
| 2018/0085383 |
SMALL MOLECULE CD38 INHIBITORS AND METHODS OF USING SAME The invention provides methods and compositions for inhibiting CD38 activity, and methods of treating or preventing various disorders associated with CD38... |
| 2018/0085382 |
COMPOSITIONS AND METHODS FOR COGNITIVE HEALTH AND MEMORY The present disclosure is a compound, a method of making the compound and method of using such compound preferably in the form of a dietary supplement that,... |
| 2018/0085381 |
Adjunctive Therapy With 25-Hydroxyvitamin D Methods, compositions, and kits for adjunctive therapy using 25-hydroxyvitamin D are disclosed. The 25-hydroxyvitamin D may be administered with an agent that... |
| 2018/0085380 |
Composition for Curing Migraine Headaches The invention is directed to methods and compositions for curing migraine headaches. In particular, compositions are described involving the combination of... |
| 2018/0085379 |
METHODS OF MONITORING ESTRIOL THERAPY Provided are methods for treating a neurodegenerative disease, such as multiple sclerosis, in a subject receiving a first estriol treatment regimen, comprising... |
| 2018/0085378 |
Antimicrobial Compound The invention relates to compounds of formula (I), and pharmaceutical uses thereof. Particular aspects of the invention relate to methods of synthesising the... |
| 2018/0085377 |
CO-CRYSTAL COMPOSITION AND ITS PHARMACEUTICAL USE This invention discloses pharmaceutical use of a dicycloplatin (DCP) for the prophylaxis or treatment of proliferative diseases, degenerative diseases,... |
| 2018/0085376 |
USE OF AEROSOLIZED LEVOFLOXACIN FOR TREATING CYSTIC FIBROSIS Methods for treating cystic fibrosis. The method includes administering to a human in need thereof an aerosol solution comprising levofloxacin or ofloxacin and... |
| 2018/0085375 |
POLYNUCLEOTIDE-POLY(DIOL) CONJUGATES, PROCESS OF PREPARATION AND USES
THEREOF The present disclosure provides a conjugate of formula (I) ##STR00001## wherein each wherein each X, Nt, R, n, m and j are as defined herein. There is also... |
| 2018/0085374 |
Use of Morpholino Compounds for the Treatment of Halitosis Use of a morpholino compound having the general formula (I) wherein R.sub.1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or... |
| 2018/0085373 |
THERAPEUTIC AND/OR PROPHYLACTIC AGENT FOR LEWY BODY DISEASE The present invention provides a therapeutic and/or prophylactic agent and the like, comprising istradefylline as an active ingredient, for Lewy body disease... |
| 2018/0085372 |
INHIBITORS OF BRUTON'S TYROSINE KINASE Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the... |
| 2018/0085371 |
COMBINATION OF PANOBINOSTAT AND RUXOLITINIB IN THE TREATMENT OF CANCER
SUCH AS A MYELOPROLIFERATIVE NEOPLASM The invention relates to a combination which comprises: (a) Compound A ((R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopenty- ... |
| 2018/0085370 |
MODULATORS OF TOLL-LIKE RECEPTORS Provided are modulators of TLRs of Formula II: ##STR00001## pharmaceutically acceptable salts thereof, compositions containing such compounds, and therapeutic... |
| 2018/0085369 |
SALTS OF QUINAZOLINE DERIVATIVE AND METHOD FOR PREPARING THE SAME The present application relates to maleates of a compound of Formula I, methods for preparing the same, pharmaceutical compositions thereof and uses thereof in... |
| 2018/0085368 |
MNK INHIBITORS AND METHODS RELATED THERETO The present invention relates to compounds according to Formula (I): ##STR00001## or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, ... |
| 2018/0085367 |
COMBINATIONS COMPRISING 3-PHENYLSULFONYL-8-PIPERAZINYL-1YL-QUINOLINE The combination of 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline or a pharmaceutically acceptable salt thereof with a second therapeutic agent, and its use for... |
| 2018/0085366 |
OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE The invention provides pharmaceutical compositions comprising macromolecular gastrointestinal enzyme-labile opioid prodrugs, co-formulated with small-molecule... |
| 2018/0085365 |
AMINO-QUINOLINES AS KINASE INHIBITORS Disclosed are compounds having the formula: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3 and Z are as defined herein, and methods of making and using the same. |
| 2018/0085364 |
PHARMACEUTICAL COMPOSITIONS COMPRISING AN ANTIPSYCHOTIC DRUG AND A VMAT2
INHIBITOR AND USES THEREOF New methods of treating schizophrenia and schizoaffective disorder by administration of pharmaceutical compositions comprising an antipsychotic compound and a... |
| 2018/0085363 |
COMBINED COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING A
BENZOPHENONE THIAZOLE DERIVATIVES AS A VDA... The present invention relates to a pharmaceutical combined composition for preventing or treating cancer comprising a compound of formula 1 or a ... |
| 2018/0085362 |
COMBINATION OF PHOSPHATIDYLINOSITOL-3-KINASE (PI3K) INHIBITOR AND A MTOR
INHIBITOR The present invention relates to a pharmaceutical combination comprising a phosphatidylinositol-3-kinase (PI3K) inhibitor compound which is a 2-carboxamide... |
| 2018/0085360 |
CENTRALLY ACTING ACETYLCHOLINESTERASE INHIBITORS FOR THE PREVENTION AND/OR
TREATMENT OF CHEMICALLY INDUCED... The invention relates to a composition for using in the treatment and/or prevention of chemically induced neuropathies, said composition comprising at least... |
| 2018/0085359 |
USE OF CHELATORS OF DIVALENT CATIONS TO PROMOTE NERVE REGENERATION Disclosed herein are methods to promote axonal outgrowth of a neuron comprising, contacting the neuron with an effective amount of a chelating agent, to... |
| 2018/0085358 |
CHROMANE, ISOCHROMANE AND DIHYDROISOBENZOFURAN DERIVATIVES AS
mGluR2-NEGATIVE ALLOSTERIC MODULATORS,... The present invention provides certain substituted chromane, isochromane, and dihydroisobenzofuran compounds of formula (I): ##STR00001## or a pharmaceutically... |
| 2018/0085357 |
CRYSTALLINE COMPOUND AS SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO)
ENZYME INHIBITOR A specific crystalline mesylate salt form of (3S)-Tetrahydrofuran-3-yl (4S)-4-isopropyl-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine-5-carboxyla- te, and the... |
| 2018/0085356 |
METHOD OF TREATING DISEASE CHARACTERISED BY PROTEIN AGGREGATE DEPOSITION
IN NEURONAL CELLS This invention relates to the use of a very low dose of tacrolimus to treat amyotrophic lateral sclerosis or Parkinson's disease. |
| 2018/0085355 |
Compositions and Methods for Inhibiting Bacterial Growth The present disclosure provides, among other a things, compositions and methods useful for inhibiting bacteria such as Mycobacterium tuberculosis. These... |
| 2018/0085354 |
METHODS OF TREATMENT FOR CHOLESTATIC AND FIBROTIC DISEASES The present invention relates to the compound [2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl]ethanoate (Nitazoxanide) or... |
| 2018/0085353 |
CONTROLLED RELEASE PHARMACEUTICAL FORMULATIONS OF NITOZOXANIDE Solid dosage formulations of nitazoxanide or a nitazoxanide analogue are provided that comprise a controlled release portion and an immediate release portion.... |
| 2018/0085352 |
Topical Localized Isoxazoline Formulation This invention provides topical localized formulations comprising an isoxazoline compound and a pharmaceutically or veterinary acceptable liquid carrier... |
| 2018/0085351 |
COMPOSITION OF A 5-HT2A SEROTONIN RECEPTOR MODULATOR USEFUL FOR THE
TREATMENT OF DISORDERS RELATED THERETO The present invention relates to certain compositions of a 5-HT.sub.2A serotonin receptor modulator and methods for their preparation. The compositions... |
| 2018/0085350 |
COMPOSITIONS AND METHODS OF TREATING CANCER The present invention provides compositions and methods for treating cancer. |
| 2018/0085349 |
STABLE PRESERVATIVE-FREE MYDRIATIC AND ANTI-INFLAMMATORY SOLUTIONS FOR
INJECTION The present invention relates to stable, preservative- and antioxidant-free liquid formulations of phenylephrine and ketorolac for injection. |
| 2018/0085348 |
METHODS FOR TREATING CANCER WITH RORGAMMA INHIBITORS The present invention provides compositions, methods, and kits comprising one or more ROR.gamma. inhibitors, alone or in combination with one or more... |
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