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Patent # Description
2018/0193503 Ultraviolet Transparent Structure for Ultraviolet Illumination
A solution for disinfecting a screen of an item using ultraviolet radiation is provided. The solution can provide an electronic device including a screen...
2018/0193502 PORTABLE UV-C DISINFECTION APPARATUS, METHOD, AND SYSTEM
A portable UV-C disinfection apparatus, method, and system for ultraviolet germicidal irradiation. UV-C emitters may be coupled to an array housing having a...
2018/0193501 FIXED POSITION HYBRID GERMICIDAL IRRADIATION APPARATUS, METHOD, AND SYSTEM
A fixed position hybrid germicidal irradiation apparatus, method, and system for ultraviolet germicidal irradiation. A plurality of emitters may be coupled to...
2018/0193500 DEVICE AND METHOD FOR STERILIZING AND STORAGE OF LABORATORY CONSUMABLES
A sterilizing and storage device comprises a housing, a door, and a plurality of ultraviolet (UV) lamps. The housing defines an interior chamber and has an...
2018/0193499 LIGHT SOURCE APPARATUS AND METHOD OF USING THE SAME
A light source apparatus comprises a main body, a plurality of light source modules and a processor. The main body includes a plurality of configuration areas...
2018/0193498 INDUCTIVE HEATING SYSTEMS AND METHODS OF CONTROLLING THE SAME TO REDUCE BIOLOGICAL CARRYOVER
Inductive heating systems and method of controlling the same to reduce biological carryover are disclosed herein. An example system includes an induction...
2018/0193497 ELECTROPORATION OF TISSUE PRODUCTS
The present disclosure provides methods for reducing bioburden on a tissue product, as well as the tissue products produced according to the disclosed methods....
2018/0193496 ANTIBODIES FOR TREATMENT AND DIAGNOSIS
The invention relates to the diagnosis and treatment of diseases, including cancer and inflammatory disorders. The invention provides, and involves the use of,...
2018/0193495 POSITRON EMITTING RADIONUCLIDE LABELED PEPTIDES FOR HUMAN UPAR PET IMAGING
There is provided a positron-emitting radionuclide labelled peptide for non-invasive PET imaging of the Urokinase-type Plasminogen Activator Receptor (uPAR) in...
2018/0193494 COMPOUND AND PHARMACEUTICAL COMPOSITION FOR TUMOR IMAGING AND TUMOR THERAPY
A compound represented by formula (I) is provided, wherein in formula (I), R.sub.1 and R.sub.2 each independently represents hydrogen, O--R.sub.3 or...
2018/0193493 RENAL IMAGING AGENT
Provided is a method for imaging a renal lesion comprising the steps of administrating a nitroimidazole-based compound to a living body and obtaining an image...
2018/0193492 CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT
Novel cromolyn analogs useful as imaging agents for detecting atherosclerotic plaques and for treating atherosclerosis and Alzheimer's Disease, and methods of...
2018/0193491 CROMOLYN DERIVATIVES AND RELATED METHODS OF IMAGING AND TREATMENT
Novel cromolyn analogs useful as imaging agents for detecting atherosclerotic plaques and for treating atherosclerosis and Alzheimer's Disease, and methods of...
2018/0193490 Beta Amyloid Staging
The present invention relates to a method of in vivo imaging and in particular to a method for the evaluation of in vivo images of beta amyloid (A.beta.)...
2018/0193489 RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS TO TARGET MEDULLARY THYROID CARCINOMA
Provided herein are nucleic acids, recombinant adeno-associated virus (rAAV) particles, and compositions, as well as methods of use thereof for transducing...
2018/0193488 ENGINEERING SYNTHETIC BRAIN PENETRATING GENE VECTORS
A synthetic gene delivery platform with a dense surface coating of hydrophilic and neutrally charged PEG, capable of rapid diffusion and widespread...
2018/0193487 GENE AND CELL THERAPY USING CELL FUSION TECHNOLOGY
The present invention relates to gene and cell therapy using a cell fusion technology and more particularly, cells overexpressing hemagglutinin neuraminidase...
2018/0193486 COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASE
Provided are methods relating to the use of CDP-therapeutic agent conjugates for the treatment of autoimmune disease, inflammatory disease, or cancer. Also...
2018/0193485 NANOPARTICLE COMPOSITION FOR USE IN TARGETING CANCER STEM CELLS AND METHOD FOR TREATMENT OF CANCER
There is disclosed a composition in the form of a nanoparticle. The nanoparticle composition has a diameter from 5 to 500 nanometers. The nanoparticle...
2018/0193484 NANOCONJUGATES ABLE TO CROSS THE BLOOD-BRAIN BARRIER
Polyvalent nanoconjugates address the critical challenges in therapeutic use. The single-entity, targeted therapeutic is able to cross the blood-brain barrier...
2018/0193483 DRUG FORMULATION BASED ON PARTICULATES COMPRISING POLYSACCHARIDE-VITAMIN CONJUGATE
The present disclosure provides formulations for pharmacologically active reagents, including formulations based on particulates formed from a biodegradable...
2018/0193482 PATTERNED DOSING OF IMMUNOSUPPRESSANTS COUPLED TO SYNTHETIC NANOCARRIERS
Provided herein are methods and related compositions for administering viral vectors and synthetic nanocarriers comprising an immunosuppressant. In some...
2018/0193481 CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODS
Antibody drug conjugates (ADC's) comprising a drug conjugated to antibody or antigen binding fragments thereof that bind to Globo series antigen disclosed...
2018/0193480 PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES
Conjugates of an antibody that binds to CD25 with PBD dimers.
2018/0193479 MEDITOPES AND MEDITOPE-BINDING ANTIBODIES AND USES THEREOF
Antibodies and meditopes that bind to the antibodies are provided, as well as complexes, compositions and combinations containing the meditopes and antibodies,...
2018/0193478 ERIBULIN-BASED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE
Linker toxins and antibody-drug conjugates that bind to human oncology antigen targets such as folate receptor alpha and/or provide anti-tubulin drug activity...
2018/0193477 DRUG-CONJUGATED BI-SPECIFIC ANTIGEN-BINDING CONSTRUCTS
Bispecific antigen-binding constructs e.g., antibodies conjugated to drugs (ADCs), which bind CD3 and other cell-surface target antigen such as tumor antigens...
2018/0193476 ENZYMATIC CONJUGATION OF ANTIBODIES
The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents,...
2018/0193475 CKIT ANTIBODY DRUG CONJUGATES
The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.
2018/0193474 Gene/carrier complex for preventing or treating inflammatory diseases
Disclosed is a gene/carrier complex for preventing or treating inflammatory diseases, including tumor necrosis factor-.alpha. converting enzyme (TNF-.alpha....
2018/0193473 COMPOSITIONS AND METHODS FOR THE TREATMENT OF PLATINUM-DRUG RESISTANT CANCER
VAR2CSA-drug conjugates for targeting and inhibiting the growth of cancer cells that have developed resistance to a platinum drug and the use of the conjugates...
2018/0193472 TRANSPORT PEPTIDES FOR TRANSCELLULAR DELIVERY OF BIOLOGICAL AND THERAPEUTIC AGENTS
Transport peptides with extraordinary ability to effectively transcellular transport cargo(s) across biological barriers have been identified. While the cargo...
2018/0193471 2GPI GENE EXPRESSION-SUPPRESSING NUCLEIC ACID CONJUGATE
The present invention provides a nucleic acid conjugate comprising: a double-stranded nucleic acid consisting of a sense strand and an antisense strand and...
2018/0193470 EGFR PROTEOLYSIS TARGETING CHIMERIC MOLECULES AND ASSOCIATED METHODS OF USE
The present disclosure relates to bifunctional compounds, which find utility as modulators of receptor tyrosine kinase (RTK) proteins. In particular, the...
2018/0193469 SURFACTANT-FREE WATER-FREE FOAMABLE COMPOSITIONS, BREAKABLE FOAMS AND GELS AND THEIR USES
A substantially surface active agent free composition which includes a hydrophobic solvent, and/or a petrolatum, a paraffin wax and/or a fatty alcohol, a fatty...
2018/0193468 TOPICAL TETRACYCLINE COMPOSITIONS
A topical therapeutic hydrophobic breakable composition includes a carrier comprising (a) about 60% to about 90% by weight of at least one hydrophobic oil; (b)...
2018/0193467 METHOD FOR PRESERVING AND STABILIZING PROTEINS FOR FORMULATIONS OF SANITARY, PHARMACEUTICAL AND COSMETIC PRODUCTS
A method for preserving and stabilizing proteins includes the steps of forming an anhydrous medium having oily phase components having hydrophilic residues,...
2018/0193466 STARCH-BASED MICROPARTICLES FOR THE RELEASE OF AGENTS DISPOSED THEREIN
The invention provides starch-based microparticles with high loading capacity for the stabilization and/or controlled release of one or more agents, for...
2018/0193465 DRUG SUSTAINED-RELEASE CARRIER AND METHOD FOR PRODUCING SAME
A DDS carrier enabling sustained release of a drug and a production method therefor. Wherein, the drug is retained by a PEG-carboxy group-containing polymer...
2018/0193464 COMPOSITIONS AND METHODS FOR INJECTION OF A BIODEGRADABLE POLYMER-BASED DELIVERY SYSTEM
A method for administering a polymeric-based delivery system to a subject is described. The method comprises contacting a housing comprising a polymer-based...
2018/0193463 Etanercept Formulations Stabilized with Combinations of Sugars and Polyols
The invention provides stabilized aqueous pharmaceutical etanercept compositions suitable for long-term storage of etanercept, methods of manufacture of these...
2018/0193462 IMPROVED LOCAL ANESTHETIC SOLUTION FOR DENTAL AND/OR CONTRAST MEDIA USE
An improved local anesthetic solution with diminished bitter taste includes an anesthetic agent, an anesthetic solution vehicle, and a bitterness suppressant....
2018/0193461 PHARMACEUTICAL COMPOSITIONS TO REDUCE COMPLICATIONS OF OCULAR STEROID
The present invention relates to pharmaceutical compositions comprising a combination of a lipid cake mixture comprising one or more phospholipids, with or...
2018/0193460 ENHANCED STABILITY KETOROLAC FORMULATIONS AND METHODS AND DEVICES FOR USE WITH SAME
Embodiments provide a more efficacious and/or more comfortable, consistent and reliable Ketorolac treatment for patients in need of same, which in some aspects...
2018/0193459 SOFT TISSUE IMPLANT
Provided herein are soft tissue implants, methods of making, use, and administration thereof. The soft tissue implants can be prepared by harvesting cells or...
2018/0193458 COMPOSITIONS AND METHODS FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic...
2018/0193457 COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF UROPATHOGENIC E. COLI INFECTION
Methods and antibody compositions that displace mannose from the binding pocket of fimbrial adhesin FimH of enterobacteria, including uropathogenic E. coli,...
2018/0193456 ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2 (VEGFR2) ANTIBODIES
Provided are anti-vascular endothelial growth factor receptor 2 (VEGFR2) antibodies, and antigen binding fragments thereof. Also provided are isolated nucleic...
2018/0193455 ANTIBODIES TO TUMOR ASSOCIATED COMPLEX N-GLYCANS WITH TERMINAL GLCNACBETA RESIDUES AND METHODS OF USE THEREOF
The present disclosure relates to antibodies specific tumor associated complex N-glycans with terminal GlcNAc.beta. residues and methods for detecting a tumor...
2018/0193454 ANTI-CD154 ANTIBODY HAVING IMPROVED BINDING, FUNCTIONAL AND SAFETY CHARACTERISTICS AND USE IN HUMAN IMMUNOTHERAPY
Improved anti-CD154 antibodies are provided herein which have improved therapeutic potency, in vivo half-life and ablated FcR binding and/or complement...
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