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Patent # Description
2018/0193453 TREATMENT-RESISTANCE REDUCING AGENT FOR TREATMENT-RESISTANT CANCER
[Problem] To provide a treatment-resistance reducing agent for treatment-resistant cancer, said treatment-resistance reducing agent being capable of...
2018/0193452 ADOPTIVE T-CELL THERAPY USING FceRI-BASED CHIMERIC ANTIGEN RECEPTORS FOR TREATING IgE-MEDIATED ALLERGIC DISEASES
A chimeric antigen receptor (CAR) contains a human Fc.epsilon.RI.alpha. extracellular domain or a mutant Fc.epsilon.RI.alpha. extracellular domain that has a...
2018/0193451 ANTIPLEXIN A1 AGONIST ANTIBODY
Provided is a novel anti-Plexin-A1 agonist antibody that promotes dendritic cell contraction. Also provided is a pharmaceutical composition comprising such an...
2018/0193450 IMMUNOGENIC COMPOSITION
The invention concerns an immunogenic composition comprising a polypeptide or a mixture of polypeptides comprising the N-terminal domain of an .alpha.-gliadin...
2018/0193449 QUAIL EGG ALLERGY ANTIGEN
The present invention provides novel antigens of an allergy to a quail egg, methods and kits for diagnosing an allergy to a quail egg, pharmaceutical...
2018/0193448 NOVEL MUCOSAL VACCINATION APPROACH FOR HERPES SIMPLEX VIRUS TYPE-2
Methods and kits for immunizing animals (e.g. mammals) against viral antigens, including herpes-simplex virus type 2 are provided. The protective immune...
2018/0193447 Concomitant Dengue and Yellow Fever Vaccination
The present invention relates to a yellow fever (YF) vaccine for use in a method for inducing a protective immune response against yellow fever, wherein said...
2018/0193446 DENGUE VACCINES
The invention relates to a protein comprising a plurality of conserved peptide sequences, or variants thereof, wherein at least one of the conserved sequences...
2018/0193445 NOVEL TARGETS OF ACINETOBACTER BAUMANNII
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising...
2018/0193444 NOVEL TARGETS OF ACINETOBACTER BAUMANNII
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising...
2018/0193443 CAMPYLOBACTER JEJUNI PEPTIDE FOR VACCINE DEVELOPMENT
Immunogenic compositions directed against C. jejuni, particularly hypervirulent strains thereof that are able to translocate the intestinal tract and cause...
2018/0193442 METHODS AND COMPOSITIONS TO PREVENT OR TREAT BACTERIAL INFECTIONS
Certain embodiments are directed to methods and compositions for preventing treating bacterial infections. In certain embodiments the compositions comprise...
2018/0193441 SWINE DYSENTERY VACCINE
The present invention relates to a composition comprising Brachyspira hyodysenteriae bacteria, particularly in the field of immunization against swine...
2018/0193440 IMMUNOGENIC COMPOSITIONS AND EXPRESSION SYSTEMS
Immunogenic compositions and vaccines against Plasmodial infection comprising an Rh polypeptide or a fragment or variant thereof are disclosed. Also disclosed...
2018/0193439 Immunotherapy against melanoma and other cancers
A method of treating a patient who has melanoma includes administering to said patient a composition containing a population of activated T cells that...
2018/0193438 ANTIFUGETACTIC AGENTS FOR THE TREATMENT OF CANCERS
This invention provides methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention provides...
2018/0193437 COMPOSITIONS AND METHODS FOR REDUCING ORGAN REJECTION BY REDUCING HEPARAN SULFATE IN DONOR TRANSPLANTS
Disclosed here are polypeptides, derived from the Myxomavirus-derived secreted glycoprotein, M-T7, comprising point mutations that interfere with...
2018/0193436 THERAPEUTIC ACID CERAMIDASE COMPOSITIONS AND METHODS OF MAKING AND USING THEM
The present invention relates to a therapeutic composition including a ceramidase mixture and a pharmaceutically acceptable carrier, where the ceramidase...
2018/0193435 HYBRID NEUROTOXINS AND USES THEREOF
The present disclosure relates to chimeric neurotoxins and uses thereof. In particular, provided herein are chimeric botulinum neurotoxins with altered...
2018/0193434 HIGH FREQUENCY APPLICATION OF BOTULINUM TOXIN THERAPY
The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a...
2018/0193433 ULTRAPURE HYPOALLERGENIC SOLUTIONS OF SACROSIDASE
One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic...
2018/0193432 ANTI-VIRAL THERAPEUTIC FOR INFECTION OF THE EYE
The present disclosure provides novel compositions and methods for treating an infection of the eye resulting from an infection of a member of the...
2018/0193431 Products and Methods for Delivery of Polynucleotides by Adeno-Associated Virus for Lysosomal Storage Disorders
The present invention relates to methods and materials useful for systemically delivering polynucleotides across the blood brain barrier using adeno-associated...
2018/0193430 COMPOSITIONS AND METHODS TO INHIBIT VIRAL REPLICATION
This disclosure provides vaccine and therapeutic active against viral infections such as herpes simplex virus 1 (HSV-1) infections.
2018/0193429 FIBROIN-DERIVED PROTEIN COMPOSITION
The invention provides a protein composition derived from silk fibroin, which composition possesses enhanced solubility and stability in aqueous solutions. The...
2018/0193428 PEPTIDE FOR PROMOTING BONE FORMATION OR INHIBITING BONE RESORPTION AND USE THEREOF
The present invention relates to a peptide for promoting bone formation or inhibiting bone resorption and use thereof. The peptide for regulating bone...
2018/0193427 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF
The invention relates to a pharmaceutical composition according to the claim 1 comprising an SGLT2 inhibitor and an insulin which is suitable in the treatment...
2018/0193426 INSULINS COMPATIBLE WITH NEW GENERATION IMPLANTABLE PUMPS
Exemplary embodiments of the present invention are directed to stabilized insulin compositions suitable for use in implantable artificial pancreatic devices....
2018/0193425 ANTI-RETROVIRAL TREATMENT USING GROWTH HORMONE
The subject invention pertains to methods of treating HIV-1 infected subject comprising the administration of growth hormone to a subject infected by HIV-1....
2018/0193424 Composition and Method for Improving Sensorineural Hearing
The present invention is directed to compositions and methods for improving hearing parameters in a human (including hearing volume, hearing range and word...
2018/0193423 PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME
This invention relates to novel compositions comprising analogs of naturally occurring polypeptides, wherein the analog comprises an .alpha.-amino acid and at...
2018/0193422 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME
This invention relates to novel compositions comprising analogs of naturally occurring polypeptides, wherein the analog comprises an .alpha.-amino acid and at...
2018/0193421 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN...
An injectable aqueous solution, of which the pH is from 6.0 to 8.0, comprising at least: a) amylin, an amylin receptor agonist or an amylin analog; b) a...
2018/0193420 THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG...
Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many...
2018/0193419 COMPOSITIONS, KITS, AND METHODS USING INTERLEUKIN-17C TO PROMOTE NEURAL GROWTH AND/OR NEURAL SURVIVAL
The present disclosure provides compositions, kits, and methods of promoting neural growth and/or neural survival using IL-17c. The compositions, kits, and...
2018/0193418 MUTATED FIBROBLAST GROWTH FACTOR (FGF) 1 AND METHODS OF USE
The present disclosure provides FGF1 mutant proteins, such as those having an N-terminal deletion, point mutation(s), or combinations thereof, which can reduce...
2018/0193417 ORNITHODOROS MOUBATA COMPLEMENT INHIBITOR FOR USE IN THE TREATMENT OF ACUTE GRAFT VERSUS HOST DISEASE
The present invention relates to methods of treating or preventing acute GVHD, comprising systemically administering to a subject in need thereof a...
2018/0193416 METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND TREATMENT OF METABOLIC DISORDERS USING SLIT2
The present invention relates to methods for identifying, assessing, preventing, and treating metabolic disorders and modulating metabolic processes using Slit2.
2018/0193415 METHODS AND AGENTS FOR TREATING ALZHEIMER'S DISEASE
The present disclosure provides compositions and methods useful for treating or preventing diseases or disorders where beta amyloid accumulation or aggregation...
2018/0193413 MAMMALIAN GLUCOSIDASE INHIBITORS, METHODS FOR THEIR USE AND PHARMACEUTICAL COMPOSITIONS THEREOF
Provided are methods, uses and pharmaceutical compositions for inhibition of mammalian alpha-amylase in a subject, with a Helianthamide peptide or a derivative...
2018/0193412 Method of In Vivo Treatment
The present disclosure teaches the treatment or prophylaxis of infection by a microorganism including a fungus or bacterium which is infecting or colonizing an...
2018/0193411 New antimicrobial peptides, their variants and uses
The present invention relates to novel antimicrobial peptide and variants thereof. The invention further relates to method of killing or inhibiting growth of...
2018/0193410 COMPOSITIONS AND METHODS FOR INHIBITING CELLULAR ADHESION OR DIRECTING DIAGNOSTIC OR THERAPEUTIC AGENTS TO RGD...
Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH--CH(CH.sub.2--SO.sub.3H)COOH or Arg-Gly-NH--CH(CH.sub.2--SO.sub.3H)COOH) and derivatives thereof, ...
2018/0193409 PEPTIDYL TPOR ANTAGONISTS AND USES THEREOF
The present invention provides a method of treating a disease or condition associated with signalling via the TPO receptor. The method comprises the step of...
2018/0193408 MODULATORS OF COMPLEMENT ACTIVITY
The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing...
2018/0193407 ANGIOTENSIN II ALONE OR IN COMBINATION FOR THE TREATMENT OF HYPOTENSION
The present invention relates, inter alia, to a method comprising administering to a subject having high output shock and undergoing treatment with a...
2018/0193406 PEPTIDE FOR SKIN REGENERATION OR WOUND TREATMENT AND USE THEREOF
The present invention relates to a peptide for skin regeneration or wound healing and a use thereof. The novel peptide according to the present invention not...
2018/0193405 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF DISEASE
The present technology is directed to compositions and methods for preventing, ameliorating, or reducing the severity of one or more signs, or symptoms...
2018/0193404 COMPOSITION FOR TREATMENT OF RSV
This invention relates to a composition, the use of a composition for treatment, and a method of treatment of infection with Respiratory syncytial virus (RSV)....
2018/0193403 HEALTHFUL SUPPLEMENTS
Healthful supplements are described herein. For example, the supplements can include at least four of the following types of nutrients: an amino acid blend, a...
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