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Patent # Description
2018/0195114 GENETIC MARKERS FOR DISCRIMINATION AND DETECTION OF VIRUSES CAUSING INFECTIOUS AQUATIC ORGANISM DISEASES, AND...
The present invention relates to genetic markers for discrimination and detection of viruses causing infectious aquatic organism diseases, and a method of...
2018/0195113 IMAGE DIFFERENTIATED MULTIPLEX ASSAYS FOR MULTIPLEX DETECTION OF DNA MUTATIONS
Provided herein are methods and kits for detecting the presence of DNA mutations in the KRAS, BRAF, CTNNB1, and APC genes. The methods and kits employ...
2018/0195112 DROPLET TAGGING CONTIGUITY PRESERVED TAGMENTED DNA
Methods and compositions for maintaining DNA contiguity for sequencing is provided.
2018/0195111 16S RIBOSOMAL RNA UNIVERSAL PRIMERS AND USE THEREOF IN MICROBIOLOGICAL ANALYSIS AND DIAGNOSTICS
The subject-matter of the invention is a pair of primers, a method of microbiological analysis of biomaterial, application of NGS sequencing method in...
2018/0195110 REAL-TIME PCR POINT MUTATION ASSAYS FOR DETECTING HIV-1 RESISTANCE TO ANTIVIRAL DRUGS
Disclosed are compositions including primers and probes, which are capable of interacting with the disclosed nucleic acids, such as the nucleic acids encoding...
2018/0195109 PLANT BASED DYE FOR STAINING OF BIOLOGICAL SAMPLES, EXTRACTION METHOD AND USES THEREOF
The present disclosure provides a composition comprising brazilein which can be used as a fluorescent dye for enhanced visualization of nucleic acids such as...
2018/0195108 DIAGNOSTIC KIT FOR VISCOELASTIC ANALYSIS AND USES AND METHODS THEREOF
A diagnostic kit for viscoelastic analysis of a sample includes a pipette tip containing constituent (A) and a measurement cup containing constituent (B),...
2018/0195107 SRM Assay to Indicate Cancer Therapy
The current disclosure provides for specific peptides, and derived ionization characteristics of the peptides, from the ALK, Ros, Ron, Ret, TS, and/or FGFR1...
2018/0195106 DEVICES, SYSTEMS AND METHODS FOR DETECTING VIABLE INFECTIOUS AGENTS IN A FLUID SAMPLE
Various devices, systems and methods for detecting a susceptibility of an infectious agent to an anti-infective are described herein. A method comprises...
2018/0195105 EXAMINATION SYSTEM, EXAMINATION DEVICE, AND EXAMINATION METHOD
The present invention optically obtains characteristic values of a plurality of biological samples from a specimen; compares the characteristic values with...
2018/0195104 Single-Molecule Platform For Drug Discovery: Methods And Apparatuses For Drug Discovery, Including Discovery Of...
The present application discloses methods and apparatuses for single molecule drug screening, discovery and validation. These methods and apparatuses allow a...
2018/0195103 METHOD FOR PRODUCING GAMMA-GLUTAMYL-VALYL-GLYCINE
A microorganism useful as an expression host for .gamma.-Glu-Val synthetase and a method for producing .gamma.-Glu-Val-Gly using .gamma.-Glu-Val synthetase...
2018/0195102 CELL EXPRESSION SYSTEM
An expression system for expressing a protein comprising: a eukaryotic host cell carrying a dihydrofolate reductase (DHFR) deficiency; and an expression...
2018/0195100 METHODS AND DEVICES FOR NUCLEIC ACID SYNTHESIS
Disclosed are devices and methods to synthesize polynucleotides and libraries of polynucleotides such as libraries of oligonucleotides. In exemplary...
2018/0195099 ENZYMATIC SYNTHESIS OF NUCLEIC ACID SEQUENCES
The disclosure generally relates to compositions and methods for the enzymatic synthesis of nucleic acid sequences. In particular embodiments 3' protected...
2018/0195098 METHOD FOR PRODUCING MALTITOL, WITH AN INCREASED YIELD
The invention relates to a method for producing maltitol, with an increased yield, in which a stage of saccharification of starch is carried out using a...
2018/0195097 MICROORGANISM PRODUCING L-LYSINE AND METHOD FOR PRODUCING L-LYSINE USING THE SAME
The present disclosure relates to a microorganism producing L-lysine and a method for producing L-lysine by using the same. More specifically, the present...
2018/0195096 Nutritional supplements and therapeutic compositions comprising (r)-3- hydroxybutyrate derivatives
Novel compounds and compositions containing (R)-3-hydroxybutyrate derivatives are disclosed. The compounds and compositions can be used as nutritional...
2018/0195095 PROCESS FOR THE BIOLOGICAL PRODUCTION OF METHACRYLIC ACID AND DERIVATIVES THEREOF
A process of producing methacrylic acid and/or derivatives thereof including the following steps: (a) biologically converting isobutyryl-CoA into...
2018/0195094 METHODS OF MAKING VANILLIN VIA THE MICROBIAL FERMENTATION OF FERULIC ACID FROM EUGENOL USING A PLANT DEHYDROGENASE
A bioconversion method of making vanillin including expressing VaoA gene in a mixture, expressing MtSAD1 gene in the mixture, feeding eugenol to the mixture,...
2018/0195093 METSCHNIKOWIA SPECIES FOR BIOSYNTHESIS OF COMPOUNDS
Provided herein are Metschnikowia species that produce useful compounds from xylose when cultured, as well as methods to make and use these Metschnikowia species.
2018/0195092 METHODS AND ORGANISM WITH INCREASED XYLOSE UPTAKE
Provided herein are novel xylose transporters and their variants, as well as nucleic acid encoding the novel xylose transporters and their variants. Provided...
2018/0195091 THERMOPHILIC MICROORGANISMS FOR CONVERSION OF LIGNOCELLULOSIC BIOMASS TO ETHANOL
It is disclosed here engineered cellulolytic microorganisms capable of producing ethanol from lignocellulosic feedstock with high yield. Multiple genes in...
2018/0195090 METHODS AND SYSTEMS FOR PRODUCING PRODUCTS USING ENGINEERED SULFUR OXIDIZING BACTERIA
Methods and systems for producing a biofuel using genetically modified sulfur-oxidizing and iron-reducing bacteria (SOIRB) are disclosed. In some embodiments,...
2018/0195089 CRISPR Oligonucleotides and Gene Editing
The present disclosure generally relates to compositions and methods for the genetic modification of cells. In particular, the disclosure relates to CRISPR...
2018/0195088 RECOMBINANT MEASLES VIRUSES EXPRESSING EPITOPES OF ANTIGENS OF RNA VIRUSES - USE FOR THE PREPARATION OF VACCINE...
The invention relates to a recombinant measles virus expressing a heterologous amino acid sequence derived from an antigen of a determined RNA virus, said...
2018/0195087 CELL FOR IMMUNOTHERAPY, INCLUDING MODIFIED NUCLEIC ACID CONSTRUCT ENCODING WILMS TUMOR GENE PRODUCT
A cell for immunotherapy of the present invention includes a nucleic acid encoding a Wilms tumor 1 gene product or a fragment of the Wilms tumor 1 gene...
2018/0195086 Minimal piggyBac Vectors for Genome Integration
Disclosed are genetic delivery systems that utilize genetic elements of the piggyBac family transposon system, and methods of introducing nucleic acid into...
2018/0195085 IMPROVED NEGATIVE-STRAND RNA VIRAL VECTOR
The present invention addresses the problem of providing an improved negative-strand RNA viral vector enabling transient high expression of a gene carried by...
2018/0195084 METHOD FOR INCREASING ABILITY OF A PLANT TO RESIST AN INVADING DNA VIRUS
The present invention discloses a method for improving the ability to resist against an intrusive DNA virus of a plant. The present invention provides a method...
2018/0195083 Improvement of Plant Yield
The invention relates to a method for improving the yield of a plant, comprising overexpressing in said plant a glutamine synthetase, said glutamine synthetase...
2018/0195082 Isolated Novel Nucleic Acid and Protein Molecules from Soybeans and Methods of Using Those Molecules to...
This disclosure provides purified nucleic acids and polypeptides. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of...
2018/0195081 TRANSGENIC PLANTS EXPRESSING LEAF-SPECIFIC PROTEINS
The invention relates to transgenic plants expressing the leaf-specific proteins.
2018/0195080 BRASSICA ROD1 GENE SEQUENCES AND USES THEREOF
The present invention relates to Brassica juncea ROD1 nucleic acid sequences and proteins and the use thereof to create plants with increased levels of C18:1...
2018/0195079 Transgenic Legumes
Embodiments of the present invention comprise altering the biosynthesis and accumulation of sucrose in legumes by transforming the plants with the sucrose...
2018/0195078 JASMONIC ACID PATHWAY ACTIVATOR
A method of increasing expression of an heterologous protein of interest in a plant or portion of the plant is provided. The method comprises treating the...
2018/0195077 METHODS OF ENHANCING TRANSLATION ABILITY OF RNA MOLECULES, TREATMENTS, AND KITS
The present invention relates to methods and a kit for enhancing the translation ability of an RNA molecule. The methods involve the use of an RNA molecule...
2018/0195076 MICROORGANISMS FOR THE PRODUCTION OF ANILINE
A non-naturally occurring microbial organism having an aniline pathway includes at least one exogenous nucleic acid encoding an aniline pathway enzyme...
2018/0195075 METHODS OF TREATING BRAIN EDEMA
Provided are methods for treating or preventing brain edema in a subject by administering an inhibitor of SLC26A11 to the subject. Also included are methods...
2018/0195074 Compositions and Methods for Inhibiting Expression of RRM2 Genes
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a RRM2 gene. The invention also relates to a ...
2018/0195073 GLUCOKINASE (GCK) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
The invention relates to double stranded ribonucleic acid (dsRNA) compositions targeting a glucokinase (GCK) gene, as well as methods of inhibiting expression...
2018/0195072 NUCLEIC ACID MOLECULES TARGETING SUPEROXIDE DISMUTASE 1 (SOD1)
Aspects of the invention relate to methods for treating ALS comprising administering to a subject in need thereof a therapeutically effective amount of a...
2018/0195071 RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS B VIRUS (HBV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC...
The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond...
2018/0195070 Compositions and Methods for Inhibiting Gene Expression of LPA
RNA interference (RNAi) agents and RNAi agent conjugates for inhibiting the expression of the LPA (apo(a)) gene are described. Pharmaceutical compositions...
2018/0195069 Alpha-1 AntiTrypsin (AAT) RNAi Agents, Compositions Including AAT RNAi Agents, And Methods of Use
RNAi agents for inhibiting the expression of the alpha-1 antitrypsin (AAT) gene, compositions including AAT RNAi agents, and methods of use are described. Also...
2018/0195068 METHODS FOR TREATING APOLIPOPROTEIN E4-ASSOCIATED DISORDERS
The present disclosure provides a method of increasing the functionality of a GABAergic interneuron in the hilus of the hippocampus of an individual having at...
2018/0195067 COMPOUNDS THAT TARGET MYC microRNA RESPONSIVE ELEMENTS FOR THE TREATMENT OF MYC-ASSOCIATED CANCER
Novel mIR-330 agents and their methods of use are provided. Methods of treating MYC-associated cancers are provided.
2018/0195066 METHODS FOR TREATING NEUROLOGICAL DISORDERS USING A SYNERGISTIC SMALL MOLECULE AND NUCLEIC ACIDS THERAPEUTIC...
In one aspect, the disclosure provides methods for treating a neurodegenerative disorder, comprising administering to a subject in need thereof a...
2018/0195065 TRANSGENIC MICROALGAE AND USE THEREOF AS A FEED FOR DELIVERY OF INTERFERING RNA MOLECULES
Provided are non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic...
2018/0195064 NOVEL THERAPEUTIC AGENT FOR A LUNG DISEASE AND/OR METHOD FOR SCREENING FOR THE SAME
Provided are a therapeutic and/or prophylactic agent for a lung disease and a method for screening for the therapeutic and/or prophylactic agent. Provided are...
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