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| Patent # | Description |
|---|---|
| 2018/0201996 |
GENOTYPING BY NEXT-GENERATION SEQUENCING Provided herein is technology relating to genotyping and particularly, but not exclusively, to methods for genotyping one or more organisms by genome sequencing. |
| 2018/0201995 |
METHODS FOR NON-INVASIVE PRENATAL PLOIDY CALLING The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample... |
| 2018/0201994 |
BALANCED CAPTURE PROBES AND METHODS OF USE THEREOF Capture probe libraries can be used to enrich a region of interest in a sequencing library for high-depth sequencing. The capture probes within the capture... |
| 2018/0201993 |
NANOPORE SEQUENCING METHODS Methods are provided for sequencing of nucleic acid templates using nanopores. A polymerase-nucleic acid complex having a strand displacing polymerase is... |
| 2018/0201992 |
METHODS AND SYSTEMS FOR GENERATION AND ERROR-CORRECTION OF UNIQUE
MOLECULAR INDEX SETS WITH HETEROGENEOUS... The disclosed embodiments concern methods, apparatus, systems and computer program products for determining sequences of interest using unique molecular index... |
| 2018/0201991 |
Systems and Methods for Sequencing T Cell Receptors and Uses Thereof Disclosed herein are methods and systems that can reconstruct, extract, and/or analyze TCR sequences using short reads. The methods and systems can be applied... |
| 2018/0201990 |
Kit, apparatus, and method for detecting chromosome aneuploidy A kit, an apparatus, and a method for detecting chromosome aneuploidy. The method comprises: sequencing the peripheral blood cell-free DNA of a pregnant woman... |
| 2018/0201989 |
OXIDANT AND USE THEREOF Provided is an oxidant including a hypervalent iodine compound which has iodobenzene micelle-incarcerated by a surfactant as a basic structure and is hydrophobic. |
| 2018/0201988 |
METHOD FOR DESIGNING PRIMER, PRIMER, PRIMER SET, DNA AMPLIFICATION METHOD,
AND ANALYSIS METHOD A method for designing a primer supplied to a PCR reaction includes a primer designing step of defining a 5'-end-side base sequence of the primer so as to... |
| 2018/0201987 |
COMPENSATION FOR SPECTRAL CROSSTALK IN MULITPLEX NUCLEIC ACID
AMPLIFICATION A method includes performing a nucleic acid amplification of a nucleic acid sample using a detection probe, wherein the nucleic acid amplification occurs over... |
| 2018/0201986 |
NUCLEIC ACID DETECTION KIT AND NUCLEIC ACID DETECTION METHOD USING
NANOPARTICLES The present invention relates to a nucleic acid detection kit and a nucleic acid detection method, which use nanoparticles. More specifically, the present... |
| 2018/0201985 |
METHODS, COMPOSITIONS, KITS, AND USES FOR ANALYSIS OF NUCLEIC ACIDS
COMPRISING REPEATING A/T-RICH SEGMENTS Described herein are methods, compositions, kits, and uses thereof for analysis of nucleic acid segments comprising a repeating A/T-rich segment, wherein the... |
| 2018/0201984 |
MAGNETIC BASE FOR COLLECTION AND RELEASE OF PARAMAGNETIC PARTICLES Provided herein are devices, systems, and methods for magnetic purification of sample components. In particular, provided herein are device bases, systems, and... |
| 2018/0201983 |
IMAGE DIFFERENTIATED MULTIPLEX ASSAYS FOR MULTIPLEX DETECTION OF DNA
MUTATIONS Provided herein are methods and kits for detecting the presence of DNA mutations in the KRAS, BRAF, CTNNB1, and APC genes. The methods and kits employ... |
| 2018/0201982 |
DISPOSABLE SENSOR A biosensor comprising a swellable biologically sensitive element comprising a nucleic acid probe and a physicoelectrical transducer associated with the... |
| 2018/0201981 |
COUMARIN COMPOUNDS AND THEIR USES AS FLUORESCENT LABELS The present application relates to new coumarin compounds and their uses as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides... |
| 2018/0201980 |
METHODS AND SYSTEMS FOR DETERMINING SPATIAL PATTERNS OF BIOLOGICAL TARGETS
IN A SAMPLE The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of... |
| 2018/0201979 |
GENETIC TESTING FOR PREDICTING RESISTANCE OF ACINETOBACTER SPECIES AGAINST
ANTIMICROBIAL AGENTS The invention relates to a method of determining an infection of a patient with Acinetobacter species potentially resistant to antimicrobial drug treatment, a... |
| 2018/0201978 |
APPARATUS FOR HIGH THROUGHPUT CHEMICAL REACTIONS Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise... |
| 2018/0201977 |
NUCLEIC ACID PRESERVATION SOLUTION AND METHODS OF MANUFACTURE AND USE Disclosed is nucleic acid preserving compositions and methods of manufacturing and using the same. Compositions include a carrier, a chaotropic agent, a... |
| 2018/0201976 |
METHODS AND TRANSPOSON NUCLEIC ACIDS FOR GENERATING A DNA LIBRARY A method for the generation of DNA fragmentation library based on a transposition reaction in the presence of a transposon end with an engineered cleaveage... |
| 2018/0201975 |
METHOD AND COMPOSITION USING A QUATERNARY AMMONIUM COMPOUND A method of determining of the presence or absence of a target RNA component in a sample, the method comprising steps of: (a) contacting the sample with a... |
| 2018/0201974 |
SAMPLE PREPARATION FOR NUCLEIC ACID AMPLIFICATION Presented herein are methods and compositions for targeted amplification of DNA and sample identification. The methods are particularly useful in validation... |
| 2018/0201973 |
Improved Detection of Methylated DNA The present invention is based on the discovery of sensitive and specific methylation detection by a) controlling excessive DNA degradation prior to conversion... |
| 2018/0201972 |
ENHANCED THROUGHPUT MINERAL COATINGS FOR OPTIMIZATION OF STEM CELL
BEHAVIOR Disclosed are methods for cell transfection and regulating cellular behavior. More particularly, the present disclosure relates to methods of non-viral cell... |
| 2018/0201971 |
AN INVENTION RELATING TO A MICROBIOLOGICAL TESTING APPARATUS The abstract particularly describes the nature of this invention and the manner in which it is to be performed:-- 1. Specific process and apparatus developed ... |
| 2018/0201970 |
SYSTEM AND METHOD FOR MEASURING SULPHITE IN FOOD SAMPLES USING AN
AMPEROMETRIC BIOSENSOR AND THE USE OF SAID... A system for measuring sulphite in food samples is provided using a biosensor, a method for determining sulphite in food samples using the biosensor, and the... |
| 2018/0201969 |
RECOMBINANT HUMAN ADA2 AND ADA2 FUSION PROTEINS AND METHODS FOR TREATING
ADA2 DEFICIENCIES The present invention is directed to isolated recombinant human ADA2 proteins, ADA2 biologically active fragments, and ADA2 fusion proteins. The proteins of... |
| 2018/0201968 |
Azidomethyl Ether Deprotection Method The invention relates to a method of converting an azidomethyl ether substituent to a free hydroxyl group. The invention also relates to methods of nucleic... |
| 2018/0201967 |
METHOD OF PRODUCING RNA FROM CIRCULAR DNA AND CORRESPONDING TEMPLATE DNA The present invention is concerned with a method of producing a target RNA using a circular DNA, wherein said method does not comprise a step of linearizing... |
| 2018/0201966 |
METHOD FOR THE SYNTHESIS OF PENTOSTATIN The present invention relates to a method for the stereo-selective production of pentostatin comprising an enzymatic transglycosylation reaction between... |
| 2018/0201965 |
METHOD FOR PRODUCING GALACTOOLIGOSACCHARIDES FROM LACTOSE Methods are disclosed for the enzymatic preparation of galactooligosaccharide (GOS) from lactose using two different microbial lactase enzymes to maximize the... |
| 2018/0201964 |
THERMOPHILIC AND THERMOACIDOPHILIC BIOPOLYMER-DEGRADING GENES AND ENZYMES
FROM ALICYCLOBACILLUS ACIDOCALDARIUS... Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from Alicyclobacillus acidocaldarius are provided. Further provided are... |
| 2018/0201963 |
TRANSAMINASE BIOCATALYSTS The present disclosure relates to polypeptides having transaminase activity, polynucleotides encoding the polypeptides, and methods of using the polypeptides. |
| 2018/0201962 |
GENERATION OF ACYL ALCOHOLS Methods, compositions, and cells for generating acyl alcohols. Compositions comprising acyl alcohols. Methods of cleaving acyl amino acids and/or acyl alcohols... |
| 2018/0201961 |
PRODUCTION OF POLYHYDROXYALKANOATES WITH A DEFINED COMPOSITION FROM AN
UNRELATED CARBON SOURCE Cells and methods for producing polyhydroxyalkanoates. The cells comprise one or more recombinant genes selected from an R-specific enoyl-CoA hydratase gene, a... |
| 2018/0201960 |
MICROORGANISM HAVING ENHANCED PRODUCTIVITY OF LACTIC ACID AND A PROCESS
FOR PRODUCING LACTIC ACID USING THE SAME The present invention relates to Saccharomyces sp. capable of producing lactic acid with a decreased activity of pyruvate decarboxylase (PDC) and increased... |
| 2018/0201959 |
PRODUCTION OF D-SORBITOL BY HYDROGENATION The present invention relates to a novel and inventive process for the production of sorbitol from D-sucrose. |
| 2018/0201958 |
GLUCOSE METABOLISM WITH MOLECULAR PURGE VALVE Provided is an engineered pathway that can function in a cell-free system, cellular system or a combination thereof to convert a sugar to a chemical or biofuel. |
| 2018/0201957 |
METHODS FOR SUSTAINING THE VIABILITY OF MICROORGANISMS DURING A CESSATION
OF SYNGAS FLOW AND PROCESSES FOR... The methods are disclosed for sustaining a population of microorganisms in an aqueous fermentation broth used in a process to convert syngas to alcohol when... |
| 2018/0201956 |
SYSTEMS AND METHODS FOR ONE-SHOT GUIDE RNA (ogRNA) TARGETING OF ENDOGENOUS
AND SOURCE DNA Engineered nucleic acids encoding genome editing system components are provided, as are engineered RNA-guided nucleases that include inserts encoded in part by... |
| 2018/0201955 |
TARGETED INTEGRATION INTO THE PPP1R12C LOCUS Disclosed herein are methods and compositions for targeted integration of an exogenous sequence into the human PPP1R12C locus, for example, for expression of a... |
| 2018/0201954 |
PSEUDOTYPING OF RETROVIRAL VECTORS, METHODS FOR PRODUCTION AND USE THEREOF
FOR TARGETED GENE TRANSFER AND HIGH... The invention relates to the pseudotyping of retroviral vectors with heterologous envelope proteins derived from the Paramyxoviridae family, genus... |
| 2018/0201953 |
COMPOUNDS AND METHODS FOR ENHANCING VIRAL GENE TRANSFER TO HUMAN
HEMATOPOIETIC CELLS Methods and compositions for enhancing viral gene transfer, such as lentiviral gene transfer, and improving the efficacy of gene delivery to cells such as... |
| 2018/0201952 |
GENE THERAPY METHODS The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The... |
| 2018/0201951 |
COMPOSITIONS, SYSTEMS AND METHODS FOR CELL THERAPY Disclosed herein are compositions and methods for cell therapy comprising an engineered cell. The present invention is directed to a composition for treating a... |
| 2018/0201950 |
Erysiphe Necator Resistance Providing Genes in Vitis Vinifera Provided herein are Erysiphe necator resistance conferring genes, plants, plant parts and seeds comprising the present resistance providing genes and the use... |
| 2018/0201949 |
HPPD-INHIBITOR HERBICIDE TOLERANCE This invention relates generally to the detection of genetic differences among soybeans. More particularly, the invention relates to soybean quantitative trait... |
| 2018/0201948 |
DROUGHT TOLERANT PLANT SYSTEM A drought resistant plant system, including transgenic plants, methods of conferring drought resistance on a plant, and methods of cultivating a plant. |
| 2018/0201947 |
NOVEL GENE FOR INCREASING PLANT BIOMASS AND USE THEREFOR An object of the present invention is to identify a novel gene that effectively increases plant biomass and to provide said gene as well as techniques... |
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