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Patent # Description
2018/0208699 POLYMERS AND USES THEREOF
The present invention provides polymers and methods of preparing the same. In certain embodiments, the polymers comprise acrylate repeating units that have...
2018/0208698 High Strength Polyisobutylene Polyurethanes
An elastomeric polymer, comprising (1) a hard segment in the amount of 10% to 60% by weight of the elastomeric polymer, wherein the hard segment includes a...
2018/0208697 Rapid self-assembled small-sized block polymer material with low quenching temperature and the preparation and...
The present invention relates to a rapid assembled small-sized block polymer material with low quenching temperature and the preparation and application...
2018/0208696 LOOSE CORE STAR POLYMERS AND LUBRICATING COMPOSITION THEREOF
The present invention relates to star polymer having a core made up of a crosslinked network of polymers derived from a mixture of one or more multi-functional...
2018/0208695 UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF
UV-absorbing polymers are provided that have at least one anhydride repeating unit that is covalently attached to at least one UV-absorbing moiety selected...
2018/0208694 METHACRYLIC RESIN COMPOSITION FOR NON-CONTACT HOT PLATE WELDING, MOLDED ARTICLE, AND METHOD FOR PRODUCING SAME
The present invention provides a methacrylic resin composition for non-contact hot plate welding comprising a methacrylic resin comprising 80 to 99.9% by mass...
2018/0208693 AN ETHYLENE-1-HEXENE-1-BUTENE TERPOLYMER AND A FILM INCLUDING THE SAME (As Amended)
The present invention relates to ethylene-1-hexene-1-butene terpolymer and a film including the same. The ethylene-1-hexene-1-butene terpolymer according to...
2018/0208692 Short Chain Branching Control on Ethylene-Butene Copolymers
A method is provided to control the short chain branching (SCB) distribution of an ethylene-butene (EB) polyethylene resin that is prepared in a gas phase...
2018/0208691 PREPARATION OF N-VINYL CARBOXAMIDES IN A SERIES OF REACTOR UNITS
Disclosed herein is a process for producing polymers of an N-vinyl carboxamide, including the steps of flowing a reaction mixture containing an aqueous liquid...
2018/0208690 CURABLE COMPOSITION
The present invention is a curable composition characterized by including a 2-cyanoacrylate and a particle containing titanium oxide and silicon oxide. The...
2018/0208689 PHOTOPOLYMERIZABLE COMPOSITION
To provide a photopolymerizable composition which can be quickly cured by light of from 300 nm to 500 nm, and a cured product of which is less colored. A...
2018/0208688 METHOD FOR SURFACE MODIFICATION OF NANOPARTICLES
A method for surface modification of nanoparticles includes the separate steps of removing ligands from the surface of the nanoparticles to form ligand-free...
2018/0208687 RUBBER COMPOSITION FOR PNEUMATIC TIRES
Provided are a rubber composition for pneumatic tires with excellent fluidity and excellent degradation resistance, and a pneumatic tire formed from the rubber...
2018/0208686 COPOLYMERIZATION OF ELEMENTAL SULFUR TO SYNTHESIZE HIGH SULFUR CONTENT POLYMERIC MATERIALS
Copolymerization of elemental sulfur with functional comonomers afford sulfur copolymers having a high molecular weight and high sulfur content. Nucleophilic...
2018/0208685 CATALYST FOR PRODUCTION OF CONJUGATED DIOLEFIN AND METHOD FOR PRODUCING SAME
A supported molded catalyst having increased hardness, the supported molded catalyst being capable of improving the long-term stability of a reaction for...
2018/0208684 PREPARATION METHOD OF ANIONIC POLYMERIZATION INITIATOR, DEVICE FOR MANUFACTURING ANIONIC POLYMERIZATION...
An method for preparing an anion polymerization initiator, a device for preparing the same and an anion polymerization initiator prepared therefrom are...
2018/0208683 METHOD FOR PREPARING SUGAMMADEX SODIUM
A process for preparing sugammadex sodium comprising: reacting a .gamma.-cyclodextrin of formula I with a halogenating agent in the presence of...
2018/0208682 Starch Extraction
The present invention relates to a process for extraction of cassava starch. Particularly, the present invention relates to a process for extraction of cassava...
2018/0208681 COMPOSITIONS, METHODS AND USES FOR ALPHA-1 ANTITRYPSIN FUSION MOLECULES
Embodiments herein report compositions of alpha-1 antitrypsin fusion polypeptides or peptide derivatives thereof. In certain embodiments, compositions and...
2018/0208680 Antibodies for Botulinum Neurotoxins
The present disclosure provides antibodies that specifically bind to botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/C, BoNT/D, BoNT/E, BoNT/F, BoNT/G, etc.)...
2018/0208679 Therapeutic Monoclonal Antibodies that Neutralize Botulinum Neurotoxins
This invention provides antibodies that specifically bind to and typically neutralize botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/E, etc.) and the...
2018/0208678 METHODS AND COMPOSITION FOR MODIFYING ENZYMES
Aspects of the disclosure relate to compositions of enzyme-binding polypeptides (EBPs) that modify the substrate specificity of an enzyme and a method for...
2018/0208677 KLOTHO BETA
The invention concerns uses of anti-KL.beta. agents, and detection of KL.beta. and/or FGF19 and/or FGFR4.
2018/0208676 Androgen Suppression, Prostate-Specific Membrane Antigen and the Concept of Conditionally Enhanced Vulnerability
Disclosed are methods of enhancing prostate cancer vulnerability to an anti-PSMA targeted therapy by administering an anti-androgen therapy to a subject so...
2018/0208675 ANTIBODIES CAPABLE OF SPECIFICALLY BINDING TWO EPITOPES ON TISSUE FACTOR PATHWAY INHIBITOR
The application discloses a combination of two monospecific TFPI antibodies, wherein one antibody is capable of specifically binding TFPI (1-181) and the other...
2018/0208674 COMBINATIONS OF EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING ANTIBODIES FOR TREATING CANCER
A method of treating triple negative breast cancer in a subject comprising administering to the subject a therapeutically effective amount of a combination of...
2018/0208673 USES OF MONOCLONAL ANTIBODY 8H9
This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention...
2018/0208671 ANTI-CD70 CHIMERIC ANTIGEN RECEPTORS
The invention provides a chimeric antigen receptor (CAR) having antigenic specificity for CD70, the CAR comprising: an antigen binding-transmembrane domain...
2018/0208670 METHODS FOR ENHANCING ANTI-TUMOR ANTIBODY THERAPY
Methods are provided to enhance the efficacy of antibody therapy directed to tumor cells.
2018/0208669 BLOCKING CD38 USING ANTI-CD38 F(ab')2 TO PROTECT NK CELLS
Provided herein are methods of inhibiting growth or proliferation of cells expressing CD38 by contacting the CD38-expressing cells with 1) NK cells bound to an...
2018/0208668 OPTIMIZED Fc VARIANTS
The present invention relates to Fc variants having decreased affinity for Fc.gamma.RIIb, methods for their generation, Fc polypeptides comprising optimized Fc...
2018/0208667 CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME
Compounds having cytotoxic and/or anti-mitotic activity are disclosed. Methods associated with preparation and use of such compounds, as well as pharmaceutical...
2018/0208666 ANTI-OX40 ANTIBODIES AND DIAGNOSTIC USES THEREOF
The invention provides antibodies immunoreactive with human OX40 and methods of using the same. The antibodies are reactive with a portion of the C-terminus of...
2018/0208665 Anti-GITR Antigen-Binding Proteins and Methods of Use Thereof
Provided herein are antigen-binding proteins (ABPs) that selectively bind to GITR and its isoforms and homologs, and compositions comprising the ABPs. Also...
2018/0208664 ANTI-CD95L ANTIBODY
The present invention relates to a specific CD95L antibody and to the use thereof in the treatment or diagnosis of diseases involving CD95L-induced signalling,...
2018/0208663 IL2RBETA/COMMON GAMMA CHAIN ANTIBODIES
Anti-CD122 and/or .gamma.c antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses...
2018/0208662 ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF
The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing...
2018/0208661 AGENTS THAT NEUTRALIZE IL-3 SIGNALLING AND USES THEREOF
The present disclosure relates to compounds that are able to bind to an interleukin (IL)-3R.alpha. chain and neutralize IL-3 signalling and uses thereof.
2018/0208660 DUAL-TARGET ANTIBODY TARGETING VEGFR-2 AND DLL4, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME
The present invention relates to a novel form of a dual-target antibody targeting VEGFR-2 and DLL4, a gene encoding the same, a recombinant expression vector...
2018/0208659 ANTI-PD-L1 ANTIBODIES AND USES THEREOF
Provided are anti-PD-L1 antibodies or fragments thereof. The antibodies or fragments thereof specifically bind to the immunoglobulin C domain of the PD-L1...
2018/0208658 CONSTRUCTS TARGETING AFP PEPTIDE/MHC COMPLEXES AND USES THEREOF
The present application provides constructs comprising an antibody moiety that specifically binds to a complex comprising an AFP peptide and an MHC class I...
2018/0208657 RECOMBINANT ANTIBODY MOLECULE AND ITS USE FOR TARGET CELL RESTRICTED T CELL ACTIVATION
The present disclosure relates to a recombinant antibody molecule, bispecific as well as tri-specific hetero-dimeric antibody molecules, as well as a method...
2018/0208656 Anti-Prokineticin Receptor (PROKR) Antibodies and Uses Thereof
The present invention provides antibodies that bind to prokineticin receptors (PROKRs) and methods of using same. According to certain embodiments of the...
2018/0208655 ANTI-GPNMB ANTIBODIES AND DIAGNOSTIC USES THEREOF
The present application discloses anti-GPNMB antibodies and methods of using the same. The antibodies are selected to bind to an epitope located in a...
2018/0208654 Antibodies Targeting CDH19 for Melanoma
The present disclosure provides a human antibody or antigen binding fragment thereof or an antibody construct comprising a human binding domain or antigen...
2018/0208653 METHODS FOR ENHANCING AN IMMUNE RESPONSE
Methods and compositions for enhancing an immune response in a subject (e.g., an immunocompromised subject or a subject with systemic lupus erythematosus...
2018/0208652 ANTI-KIR ANTIBODIES, FORMULATIONS, AND USES THEREOF
A novel IgG4 isotype anti-KIR antibody, novel formulations of this and other IgG4 anti-KIR antibodies, and methods of using such formulations are provided....
2018/0208651 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR FABRICATION OF SOLID MASSES COMPRISING POLYPEPTIDES AND/OR PROTEINS
Embodiments of the invention provide shaped masses (SM) comprising one or more drugs such as proteins or polypeptides and methods for forming and delivering...
2018/0208650 BONE-TARGETING ANTIBODIES
Provided are recombinant and chemically-conjugated antibodies and fragments thereof modified with one or more poly-aspartate (poly-D) peptides (e.g., a D10...
2018/0208649 METHODS FOR DIAGNOSING AND TREATING AFFECTIVE DISORDERS
The methods of the present invention are useful for determining whether an individual has or is at risk of developing an affective disorder by detecting the...
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