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Patent # Description
2018/0207282 GUMMY DOSAGE FORMS COMPRISING SERINE
The present disclosure describes a gummy dosage form including: an amino acid in an amount of about 20% by weight or greater; a hydrophilic bulking agent; and...
2018/0207281 POLYSACCHARIDE-BASED HYDROGELS AND HYBRID HYDROGELS AND PRECURSORS THEREOF, METHODS OF MAKING SAME, AND USES...
Hydrogels and hybrid hydrogels, methods of making the hydrogels/hybrid hydrogels, and methods of using the hydrogels/hybrid hydrogels. The hydrogels have...
2018/0207280 STABLE TRANSDERMAL AMPHETAMINE COMPOSITIONS AND METHODS OF MANUFACTURE
Described are transdermal drug delivery compositions comprising amphetamine, methods of making transdermal drug delivery compositions comprising amphetamine,...
2018/0207279 METHODS OF TREATING ULCERATIVE COLITIS
Methods for maintaining clinical remission of ulcerative colitis in a human patient are described comprising administration of an antibody that has binding...
2018/0207278 LIQUID FORMULATION COMPRISING GM-CSF NEUTRALIZING COMPOUND
The present invention relates to aqueous formulations comprising a compound neutralizing GM-CSF in concentrations of at least about 20 mg/ml, a tonicity...
2018/0207277 Stable Fat-soluble Active Ingredient Composition, Microcapsule and Process Of Preparation and Use Thereof
The present invention provides a stable fat-soluble active ingredient composition, microcapsule and process for preparation and use thereof. The fat-soluble...
2018/0207276 MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF
Methods and compositions are provided for extending the half-life of a therapeutic agent. One half-life extending moieties may be attached to a therapeutic...
2018/0207275 TOPICAL FORMULATIONS AND TREATMENTS
Provided is a pharmaceutical formulation and a method associated therewith for treating bacterial vaginosis. The pharmaceutical formulation includes from 10 to...
2018/0207274 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These...
2018/0207272 GENETICALLY MODIFIED ANTI-THIRD PARTY CENTRAL MEMORY T CELLS AND USE OF SAME IN IMMUNOTHERAPY
An isolated cell having a central memory T-lymphocyte (Tcm) phenotype, the cell being tolerance-inducing cell and capable of homing to the lymph nodes...
2018/0207271 IL-26 INHIBITORS
The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by...
2018/0207270 Methods of Using Interleukin-10 for Treating Diseases and Disorders
Methods of modulating immune responses in subjects having oncology- and immune-related diseases, disorders and conditions by the administration of an IL-10...
2018/0207269 Methods of Treating CD166-Expressing Cancer
It has now been discovered that activated lymphocyte cell adhesion molecule (ALCAM)-also known as CD166-is the ligand of the innate immune receptor ILT3 that...
2018/0207268 COMBINATION THERAPY FOR CANCER
The present invention relates to a combination of an anti-human VEGFR2 antibody, preferably ramucirumab, and ...
2018/0207267 ISOFORM-SPECIFIC, CONTEXT-PERMISSIVE TGFB1 INHIBITORS AND USE THEREOF
Disclosed herein are therapeutic use of isoform-specific, context-permissive inhibitors of TGF.beta.1 in the treatment of disease that involve TGF.beta.1...
2018/0207266 MODULATION OF TUMOR IMMUNITY
Methods of treating proliferative disorders are described. In particular, combination treatment with a GITR agonist and a PD-1 antagonist are provided.
2018/0207265 A NOVEL IL33 FORM, MUTATED FORMS OF IL33, ANTIBODIES, ASSAYS AND METHODS OF USING THE SAME
The present invention provides isolated IL-33 proteins, active fragments thereof and antibodies, antigen binding fragments thereof, against IL-33 proteins....
2018/0207264 PORCINE IMMUNE MODULATION MODEL
A method of modulating an immune response. The method includes administering a treatment comprising delta 5-androsten-3B, 17B-diol, delta 5-androsten-3B, 7B,...
2018/0207263 TREATMENT OF CANCER WITH NALTREXONE
The present invention provides novel therapeutic applications of low dose naltrexone (LDN). Said applications have been determined in light of the discovery by...
2018/0207262 PNEUMOCOCCAL CAPSULAR SACCHARIDE CONJUGATE VACCINE
The present invention is in the field of pneumococcal capsular saccharide conjugate vaccines. Specifically, an immunogenic composition for infants is provided...
2018/0207261 HUMAN HERPESVIRUS IMMUNOTHERAPY
An isolated protein comprises respective amino acid sequences of each of a plurality of CTL epitopes from two or more different herpesvirus antigens and...
2018/0207260 PORCINE EPIDEMIC DIARRHEA VIRUS VACCINE
The present invention relates to a vaccine for protecting a pig against diseases associated with porcine epidemic diarrhea virus. The vaccine commonly includes...
2018/0207259 BIOCHEMICALLY STABILIZED HIV-1 ENV TRIMER VACCINE
Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly...
2018/0207258 ADJUVANTED INFLUENZA VACCINES FOR PEDIATRIC USE
An influenza vaccine adjuvanted with a sub-micron oil-in-water emulsion elicits significantly higher immune responses in human pediatric populations. Compared...
2018/0207257 TRUNCATED L1 PROTEIN OF HUMAN PAPILLOMAVIRUS TYPE 11
The invention relates to a truncated L1 protein of the Human Papillomavirus Type 11, a virus-like particle consisting of the protein, a vaccine comprising said...
2018/0207256 NOVEL TARGETS OF ACINETOBACTER BAUMANNII
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising...
2018/0207255 IMMUNOGENIC COMPOSITIONS CONTAINING BACTERIAL OUTER MEMBRANE VESICLES
This invention relates to outer membrane vesicles (OMVs) from Gram-negative bacteria. The vesicles comprise heterologous proteins or immunogenic fragments...
2018/0207254 HLA-DR-BINDING ANTIGEN PEPTIDE DERIVED FROM WT1
The present invention provides a WT1-derived HLA-DRB1*0405-binding antigen peptide, a polynucleotide encoding said peptide, a helper T cell inducer comprising...
2018/0207253 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST HEPATOCELLULAR CARCINOMA (HCC) AND...
A method of eliciting an immune response in a patient who has a cancer includes administering to said patient a composition containing a population of...
2018/0207252 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST HEPATOCELLULAR CARCINOMA (HCC) AND...
A method of treating a patient who has a cancer includes administering to said patient a composition containing a population of activated T cells that...
2018/0207251 NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST PANCREATIC CANCER AND OTHER CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2018/0207250 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR INDUCING IMMUNE TOLERANCE BY MUCOSAL VACCINATION WITH FC-COUPLED...
The present invention relates to methods and pharmaceutical compositions of inducing immune tolerance by mucosal vaccination with Fc-coupled antigens. In...
2018/0207249 METHOD AND VACCINE COMPRISING COPOLYMER 1 FOR TREATMENT OF PSYCHIATRIC DISORDERS
Copolymer 1, a Copolymer 1-related peptide, a Copolymer 1-related polypeptide; and T cells activated therewith are useful in methods and compositions for...
2018/0207248 COMPOSITIONS AND METHODS FOR MODULATING AND/OR STIMULATING IMMUNE RESPONSES IN HUMAN AND/OR ANIMAL
There is provided a composition including parietal polysaccharides from at least one Candida species and parietal polysaccharides from at least one different...
2018/0207247 METHODS OF TRANSPLANTATION AND DISEASE TREATMENT
A method of transplantation is disclosed. The method comprising administering to a subject in need of transplantation of cells in suspension, a therapeutically...
2018/0207246 COMPOSITIONS AND METHODS FOR TREATING POST-OPERATIVE COMPLICATIONS OF CARDIOPULMONARY SURGERY
A method for preventing bleeding, blood-brain barrier disruption, brain injury, or a combination thereof in a subject destined for cardiac surgery is...
2018/0207245 STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized...
2018/0207244 Factor IX Polypeptides and Methods of Use Thereof
The present invention provides methods of administering Factor IX; methods of administering chimeric and hybrid polypeptides comprising Factor IX;...
2018/0207243 METHODS AND COMPOSITIONS FOR RNA-GUIDED TREATMENT OF HIV INFECTION
A method of treating a subject having or at risk for having an HIV-1 virus infection, by administering to the subject a therapeutically effective amount of a...
2018/0207242 Treatment of Cognitive Impairment of Mucopolysaccharidosis Type IIIA by Intrathecal Delivery of Heparan N-Sulfatase
The present invention provides, among other things, effective treatment for Sanfilippo Syndrome Type A (MPS IIIA) based on intrathecal delivery of recombinant...
2018/0207241 PEPTIDE HAVING FIBROSIS INHIBITORY ACTIVITY AND COMPOSITION CONTAINING SAME
The present invention relates to a composition for inhibiting fibrosis and more specifically, to a composition for inhibiting fibrosis, wherein the composition...
2018/0207240 COLLAGEN IV REPLACEMENT
Disclosed are pharmaceutical compositions, formulations, and methods for treating Alport syndrome by administering recombinant human collagen IV protein to a...
2018/0207239 USE OF C-TYPE NATRIURETIC PEPTIDE VARIANTS TO TREAT SKELETAL DYSPLASIA
The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP...
2018/0207238 COMPOSITIONS AND METHODS FOR REGULATING LEUKOCYTE ADHESION
Inflammatory cell recruitment to local sites of tissue injury and/or infection is controlled by many signaling processes influencing cell-to-cell interactions...
2018/0207237 IL-12 FORMULATIONS FOR ENHANCING HEMATOPOIESIS
Provided are formulations for proteins to be injected into mammals. Specifically, formulations for recombinant IL-12 in mice and primates.
2018/0207236 METHODS AND COMPOSITIONS USING GDF15 POLYPEPTIDES FOR INCREASING RED BLOOD CELLS
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including...
2018/0207235 NEUROPROTECTIVE AGENTS DERIVED FROM SPIDER VENOM PEPTIDES
The invention relates to disulfide-rich peptides derived from spider venom and their use, particularly as neuroprotective agents. The invention also relates to...
2018/0207234 INHIBITION OF CANCER GROWTH AND METASTASIS
The present invention relates to methods for treating or preventing cancer and metastasis. More particularly, the present invention relates to methods for...
2018/0207233 TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND OTHER EYE DISEASES WITH APOLIPOPROTEIN MIMETICS
The present disclosure provides apolipoprotein (apo) mimetics useful for the treatment of age-related macular degeneration (AMD) and other eye disorders. The...
2018/0207232 Soy-Derived Bioactive Peptides for Use in Compositions and Methods for Wound Healing, Tissue Engineering, and...
Compositions and methods for the promotion of wound healing and tissue regeneration are described. The compositions and methods make use of water-soluble soy...
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