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Patent # Description
2018/0207231 POLYPEPTIDES COMPRISING A MODIFIED BACTERIOPHAGE G3P AMINO ACID SEQUENCE LACKING A GLYCOSYLATION SIGNAL
The invention relates to polypeptides that comprise a portion of filamentous bacteriophage gene 3 protein (g3p) sufficient to bind to and/or disaggregate...
2018/0207230 AUTOCLAVABLE SUSPENSIONS OF CYCLOSPORIN A FORM 2
Disclosed herein are autoclavable formulations of cyclosporin A Form 2, methods of making such formulations, and methods of treating diseases of the eye with...
2018/0207229 FORMULATIONS OF GUANYLATE CYCLASE C AGONISTS AND METHODS OF USE
The invention provides low-dose formulations of guanylate cyclase-C ("GCC") agonist peptides and methods for their use. The formulations of the invention can...
2018/0207228 PEPTIDE COMBINATIONS AND USES THEREOF FOR TREATING GRASS ALLERGY
The invention relates to combinations of peptides derived from a portion of an amino sequence of a grass pollen allergen, e.g. the allergens Phl p 1, Phl p 2,...
2018/0207227 Therapeutic and Neuroprotective Peptides
Nonnatural peptides and their methods of use in human or non-human animal subject to cause an effect such as: nuroprotection, protecting against or lessening...
2018/0207226 COMPOSITIONS AND METHODS FOR INHIBITION OF BACTERIAL INFECTIONS IN HUMAN ENDOCERVIX
Provided are compositions, methods and devices for prophylaxis and/or therapy of sexually transmitted bacterial infections that infect the female reproductive...
2018/0207225 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF FRIEDREICH'S ATAXIA
The disclosure provides methods of preventing or treating Friedreich's ataxia in a mammalian subject, reducing risk factors, signs and/or symptoms associated...
2018/0207224 APPLICATION OF DIPEPTIDE AS ACE ENZYME ACTIVITY INHIBITOR
An application of dipeptide as an ACE enzyme activity inhibitor. Virtual screening is performed on 400 types of dipeptide based on ACE inhibiting effects...
2018/0207223 PCSK9 INHIBITORY POLYPOLYPEPTIDES AND METHODS OF USE
The present invention relates to PCSK9 inhibitors and methods of use thereof. Specifically, the invention relates to PCSK9 cell-based assay, PCSK9 inhibiting...
2018/0207222 COMPOSITION FOR ALLEVIATING SKIN INFLAMMATION CAUSED BY YELLOW DUST AND FINE PARTICULATE, COMPRISING NATURAL...
The present invention relates to a composition comprising natural plant extracts for alleviating inflammation caused by yellow dust and fine particulate,...
2018/0207221 Sour Cherry Topical Therapeutic Formulations, Method of Manufacture and Method of Treatment of Human...
A biotherapeutic anti-inflammatory composition, its method of manufacture and method of treatment of various diseases, the composition having an efficacious...
2018/0207220 Sour Cherry Topical Therapeutic Formulations, Method of Manufacture and Method of Treatment of Human...
A biotherapeutic anti-inflammatory composition, its method of manufacture and method of treatment of various diseases, the composition having an efficacious...
2018/0207219 CHINESE MEDICINE HANGOVER CURING AGENT
A Chinese medicine hangover curing agent. The agent is prepared from Chinese Hawthorn, Folium nelumbinis, Folium mori, Taraxaci herba, Lophatheri herba, common...
2018/0207218 PLANT EXTRACTIONS, COMPOSITIONS CONTAINING SAME, AND USES THEREOF
This disclosure relates to plant extracts selected from Bacopa plant extracts, Centella plant extracts, Jatropha plant extracts, Aegle plant extracts,...
2018/0207217 Method for Relieving Memory Dysfunction Using Puerariae Radix Extract
A method for relieving memory dysfunction using Puerariae Radix Extract is provided, including decocting Puerariae Radix in water, concentrating the extracted...
2018/0207216 Compositions and Methods for Treating Multi-Drug Resistant Malaria
A method is provided for treating an individual for a malarial infection, in particular drug-resistant species of Plasmodium, including administering to the...
2018/0207215 SHENLINGBAIZHU GRANULES AND PREPARATION METHOD THEREOF
Disclosed are shenlingbaizhu granules and a preparation method thereof, wherein the shenlingbaizhu granules comprise an extract of raw material medicines and...
2018/0207214 Reproductive Cell Maintenance System
Extracts obtained from the genus Hippophae or other plant sources or compositions produced by chemical or molecular biological techniques each having in common...
2018/0207213 TOPICAL ANTIVIRAL FORMULATIONS AND METHODS OF USING THE SAME
Antiviral pharmaceutical compositions comprising one or more cannabinoid compounds in the form of lip-balms, creams and ointments. A specific embodiment...
2018/0207212 USE OF ONCOLYTIC HERPES SIMPLEX VIRUS, ALONE OR IN COMBINATION WITH IMMUNE CHECK-POINT INHIBITOR, IN THE...
An oncolytic herpes simplex virus is disclosed for use in a method of treating cancer, the method comprising administering one or more doses of an oncolytic...
2018/0207211 RESPIRATORY SYNCYTIAL VIRUS WITH A GENOMIC DEFICIENCY COMPLEMENTED IN TRANS
The invention relates to pneumoviral virions comprising a viral genome that has a mutation in a gene coding for a protein that is essential for infectivity of...
2018/0207210 LACTOBACILLI FOR TREATING CARDIAC DYSFUNCTION
The use of a bacterium of the species Lactobacillus salivarius in the manufacture of a food product, dietary supplement or medicament for treating cardiac...
2018/0207209 BIFIDOBACTERIA FOR TREATING CARDIAC CONDITIONS
This invention relates to new uses of Bifidobacteria (particularly, although not exclusively, probiotic Bifidobacteria), and to food products, feed products,...
2018/0207208 COMPOSITIONS COMPRISING BACTERIAL STRAINS
Provided are compositions comprising a bacterial strain of the genus Blautia, for use in a method of increasing the microbiota diversity and/or inducing...
2018/0207207 COMPOSITIONS COMPRISING BACTERIAL STRAINS
The invention provides compositions comprising one or more bacterial strains for treating preventing diarrhea and/or constipation.
2018/0207206 TREATMENT TO PROMOTE WOUND HEALING
The invention relates to a field of tissue repair and regeneration. More particularly, the invention relates to a composition for promoting cutaneous wound...
2018/0207205 Compositions and Methods of Using Krill Powder in Cardiovascular Regulation
The present invention is related to the regulation of the cardiovascular system. In particular, to krill powder compositions and their administration to mammal...
2018/0207204 KRILL OIL PREPARATIONS WITH OPTIMAL MINERAL AND METAL COMPOSITION, LOW IMPURITIES AND LOW AND STABLE TMA LEVELS
A Krill oil preparation including a reduced amount of trimethylamine of 5 mgN/100 g or less, or more than 700 ppm by weight of endogenous calcium and/or less...
2018/0207203 PORTABLE APPARATUS WITH MIXING DEVICE AND METHODS RELATING TO COLLECTING AND PROCESSING HUMAN BIOLOGICAL...
A portable apparatus for collection and processing of human biological material containing adipose, such as extracted during a lipoplasty procedure, is useful...
2018/0207202 METHODS FOR MOBILIZING HEMATOPOIETIC STEM CELLS
Disclosed are methods of mobilizing hematopoietic cells in a subject by administering to the subject a combination of Flt3 ligand (FLT3L) and a cell adhesion...
2018/0207201 PROCESSES FOR PRODUCTION OF TUMOR INFILTRATING LYMPHOCYTES AND USES OF SAME IN IMMUNOTHERAPY
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for...
2018/0207200 DUAL USE ORAL PHARMACEUTICAL COMPOSITION TABLETS OF SULFATE SALTS AND METHODS OF USE THEREOF
The present invention is generally directed to an oral pharmaceutical tablet composition comprising a sulfate salt, for example, sodium sulfate, wherein the...
2018/0207199 NEW USE OF HYALURONIC ACID
A gel containing hyaluronic acid in a crosslinked form or in a mixture of a crosslinked and non-crosslinked form is injected into the periosteum of a bone in...
2018/0207198 COMPOSITIONS BASED ON METHYL CYCLODEXTRINS FOR THE TREATMENT AND/OR PREVENTION OF DISEASES BY INCREASING THE...
Pharmaceutical composition and their uses are disclosed, the composition comprising at least one methyl cyclodextrin having a molar substitution (MS) degree of...
2018/0207197 OLIGONUCLEOTIDE DERIVATIVE
The present invention provides an oligonucleotide derivative having, at an oxygen atom of at least one phosphate group of an oligonucleotide, a group...
2018/0207196 METHODS RELATING TO LUNG CANCER
The methods and assays described herein relate to detection, diagnosis, and treatment of lung cancer, e.g., by detecting the level of expression of certain...
2018/0207195 OXIDIZED A-1,4-OLIGOGLUCURONIC ACID, AND PREPARATION METHOD THEREFOR AND USES THEREOF
An oxidized .alpha.-1,4-oligoglucuronic acid, and a preparation method therefor and uses thereof. By using abundant starch, especially soluble starch, in the...
2018/0207194 OXIDIZED B-1,4-OLIGOGLUCURONIC ACID, AND PREPARATION METHOD THEREFOR AND USES THEREOF
An oxidized .beta.-1,4-oligoglucuronic acid, and a preparation method therefor and uses thereof. By using abundant cellulose in the natural world as the raw...
2018/0207193 COMPOSITIONS AND METHODS FOR IMPROVING ENZYME REPLACEMENT THERAPY FOR LYSOSOMAL STORAGE DISEASES
The present disclosure provides compositions and methods for improving the efficacy of enzyme replacement therapy for lysosomal storage diseases.
2018/0207192 SUBSTANCE AND METHOD FOR MODULATING PROLIFERATION AND DIFFERENTIATION OF REGULATORY, STEM AND OTHER SOMATIC CELLS
The invention relates to the field of basic biology, practical regenerative medicine, veterinary, cell biology and can be used to treat and prevent diseases,...
2018/0207191 HUMAN CANCER MICRO-RNA EXPRESSION PROFILES PREDICTIVE OF CHEMO-RESPONSE
Disclosed are identified and successfully targeted microRNAs (miRNAs) associated with human cancer cell line response to a range of anti-cancer agents. The...
2018/0207190 COMPOSITION CONTAINING NAD FOR PREVENTING AND TREATING OBESITY OR IMPAIRED GLUCOSE TOLERANCE
A pharmaceutical composition containing nicotinamide adenine dinucleotide (NAD) as an active ingredient for preventing and treating obesity or impaired glucose...
2018/0207189 SELECTIVE INHIBITORS OF Alpha2-CONTAINING ISOFORMS OF Na,K-ATPase AND USE THEREOF FOR REDUCTION OF INTRAOCULAR...
Provided herein are alpha2-selective Na,K-ATPase inhibitors and prodrugs thereof, characterized by having a cyclic moiety attached to a digoxin or digitoxin...
2018/0207188 TREATMENT OF PAPULOPUSTULAR ROSACEA WITH IVERMECTIN
Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an...
2018/0207187 COMPOSITION FOR OPTIC NERVE PROTECTION
A composition for optic nerve cell protection, for preventing or treating glaucoma, for suppressing retinal ganglion cell death, or for delaying a progression...
2018/0207186 FORMULATION OF GLUCOSINOLATES AND MYROSINASE
Disclosed is a formulation which contains microcapsules which contain a core containing an extract rich in glucosinolates obtained from crucifers and a...
2018/0207185 METHODS OF TREATING MYELODYSPLASTIC SYNDROMES WITH A COMBINATION THERAPY USING LENALIDOMIDE AND AZACITIDINE
Methods of treating, preventing and/or managing myelodysplastic syndromes are disclosed. Specific methods encompass the administrations of ...
2018/0207184 METHODS FOR TREATING CHEMORESISTANT CANCER-INITIATING CELLS
The disclosure provides methods of treating cancer by selectively inhibiting p-S.sup.552-.beta.-catenin, p-T.sup.217-.beta.-catenin, ...
2018/0207183 PHARMACEUTICAL COMPOSITIONS COMPRISING CYCLIC BORONIC ACID ESTER DERIVATIVES
Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to cyclic...
2018/0207182 DOSAGE FORMS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING DISEASE
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
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