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Patent # Description
2018/0214547 TREATMENT OF CANCER USING A COMBINATION OF AN ANTI-PD-1 ANTIBODY AND IL-6
This disclosure provides a method for treating a subject afflicted with a cancer, which method comprises administering to the subject therapeutically effective...
2018/0214546 MODULATION OF SRPX2-MEDIATED ANGIOGENESIS
The present invention relates to nucleic acids and antibodies against SRPX2 and SRPX2 protein function in angiogenesis. Angiogenesis-related conditions, such...
2018/0214545 NOVEL METHODS AND REAGENTS FOR DIAGNOSING SJOGREN'S SYNDROME
The inventive subject matter relates to novel antibodies to lacritin splice variants, improved methods for detecting lacritin splice variants, and methods for...
2018/0214544 HEMATOPOIETIC STEM CELLS IN COMBINATORIAL THERAPY WITH IMMUNE CHECKPOINT INHIBITORS AGAINST CANCER
The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoietic stem cell mobilization yield...
2018/0214543 Motile Sperm Domain Containing Protein 2 and Inflammation
Disclosed herein are methods of treating, preventing, or reducing the incidence of an inflammatory disease or disorder and methods of inhibiting, preventing,...
2018/0214542 HUMANIZED CXCR3 ANTIBODIES WITH DEPLETING ACTIVITY AND METHODS OF USE THEREOF
Provided are humanized CXCR3 antibodies and methods of using the antibodies to treat CXCR3-associated disorders such as type 1 diabetes mellitus (T1D),...
2018/0214541 Haemophilus influenzae fusion protein and construction method and use thereof
Provided are a fusion protein and a construction method thereof. The fusion method consists of: a Haemophilus influenzae protein D and a Hin47 (Htra) protein....
2018/0214540 METHOD FOR ELICITING AN IMMUNE RESPONSE TO AN IMMUNOGEN
The invention relates to methods for eliciting an immune response to an immunogen, and in particular, to such methods using polymersomes as carriers for...
2018/0214539 IMMUNOGENIC PROTEIN PAS N 1 FROM BAHIA GRASS POLLEN
The present invention relates generally to novel recombinant polypeptides of Bahia grass pollen and to genetic sequences encoding same. More particularly, the...
2018/0214538 GENERATION OF ANTIBODIES TO TUMOR ANTIGENS AND GENERATION OF TUMOR SPECIFIC COMPLEMENT DEPENDENT CYTOTOXICITY...
The present invention relates to methods and compositions for use in inducing tumor-specific antibody mediated complement-dependent cytotoxic response in an...
2018/0214537 METHOD FOR PRODUCING RNA COMPOSITIONS
The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or...
2018/0214536 VACCINE COMPOSITION AGAINST CHLAMYDIACEAE INFECTIONS
The invention relates to vaccine compositions for treating and/or preventing infections by a bacterium of the Chlamydiaceae family, said compositions...
2018/0214535 NOVEL TARGETS OF ACINETOBACTER BAUMANNII
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising...
2018/0214534 NOVEL TARGETS OF ACINETOBACTER BAUMANNII
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising...
2018/0214533 NOVEL TARGETS OF ACINETOBACTER BAUMANNII
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising...
2018/0214532 NEISSERIA MENINGITIDIS COMPOSITIONS AND METHODS THEREOF
In one aspect, the invention relates to a composition including a factor H binding protein (fHBP) and a Neisseria meningitidis non-serogroup B capsular...
2018/0214531 MENINGOCOCCUS VACCINES
Meningococcal vaccines can be improved by including multiple alleles or variants of fHbp, in order to provide broader coverage of the diversity which is known...
2018/0214530 Streptococcus Pneumoniae Protein Antigen, and Preparation Method and Use Thereof
Provided are a fusion protein of a pneumococcal surface adhesin A (PsaA) and a pneumococcal surface protein A (PspA), and preparation method and use thereof....
2018/0214529 EDIBLE VACCINATION AGAINST MICROBIAL PATHOGENS
The present invention relates to animals and more specifically to insects. In more details the invention relates to an edible composition or insect artificial...
2018/0214528 PHARMACEUTICAL COMPOSITION FOR INHIBITING EXPRESSION OF CD47 IN TUMOR CELLS AND USE OF SAME
The pharmaceutical composition for inhibiting expression of CD47 in tumor cells provided by the present invention contains: exosomes produced by cultured...
2018/0214527 BI-SPECIFIC TARGETED CHIMERIC ANTIGEN RECEPTOR T CELLS
T cells expressing a chimeric antigen receptor and a T cell receptor specific for CMV (bi-specific T cells) are described as a methods for using such cells in...
2018/0214526 IMMUNOTHERAPY WITH BINDING AGENTS
Binding agents that modulate the immune response are disclosed. The binding agents may include soluble receptors, polypeptides, and/or antibodies. Also...
2018/0214525 MODIFIED YEAST-BRACHYURY IMMUNOTHERAPEUTIC COMPOSITIONS
Disclosed are improved yeast-based immunotherapeutic compositions comprising modified Brachyury antigens, and methods for the prevention and/or treatment of...
2018/0214524 NON-GENOTOXIC CONDITIONING REGIMEN FOR STEM CELL TRANSPLANTATION
The present invention provides a clinically applicable method of stem cell transplantation that facilitates engraftment and reconstitutes immunocompetence of...
2018/0214523 INJECTION SOLUTION FOR RNA
The invention relates to the use of RNA and an aqueous injection buffer containing a sodium salt, a calcium salt and optionally a potassium salt and optionally...
2018/0214522 CRYSTALLIZED OXALATE DECARBOXYLASE AND METHODS OF USE
Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a...
2018/0214521 METHODS AND COMPOSITIONS FOR RNA-GUIDED TREATMENT OF HIV INFECTION
A method of immunizing a subject at risk of HIV-1 virus infection, by administering to the subject a prophylactically effective amount of a composition...
2018/0214520 TISSUE MATRIX MATERIALS AND ENZYMATIC ADHESIVES
The present application relates to use of transglutaminases to treat various tissue matrix products. The methods can include application of a transglutaminase...
2018/0214519 COMBINATION THERAPIES FOR MODULATION OF HISTONE METHYL MODIFYING ENZYMES
Provided herein are pharmaceutical compositions comprising an EZH2 inhibitor and a type I interferon, processes for preparing such pharmaceutical compositions,...
2018/0214518 USING NUCLEIC ACIDS ENCODING NAP-2 AND TGF-ALPHA POLYPEPTIDES TO IMPROVE CARDIAC FUNCTION
This document provides methods and materials for reducing the risk of major adverse cardiac events. For example, methods and materials for identifying patients...
2018/0214517 COLONY STIMULATING FACTOR FOR USE IN PANCREATIC OR COLON CANCER TREATMENT
There is provided a Colony Stimulating Factor (CSF) as an active ingredient for use in the treatment of colon or pancreatic cancer through an increase in...
2018/0214516 APOAEQUORIN-CONTAINING COMPOSITIONS AND METHODS OF USING SAME TO TREAT NEURONAL INFLAMMATION
The present invention is directed to methods of preconditioning neurons to reduce neuronal inflammation in a subject. Such methods include a step of...
2018/0214515 PEPTIDYLIC INHIBITORS TARGETING C9ORF72 HEXANUCLEOTIDE REPEAT-MEDIATED NEURODEGENERATION
The present invention provides for a novel peptide inhibitor and method for treating neurological disorders related to a hexanucleotide (GGGGCC) repeat...
2018/0214514 Compositions and Treatments of Metabolic Disorders Using FGF Binding Protein 3
The invention relates to methods of treating a metabolic disorder in a subject, the method comprising administering fibroblast growth factor binding protein 3...
2018/0214513 Restoration of Visual Responses by In Vivo Delivery of Rhodopsin Nucleic Acids
Nucleic acid vectors encoding light-gated cation-selective membrane channels, in particular channelrhodopsin-2 (Chop2), converted inner retinal neurons to...
2018/0214512 ANTI-PATHOGENIC METHODS
The protection of plants and human and non-human subjects from pathogens enables a multivalent approach to inhibiting pathogen infection in plant and human and...
2018/0214511 ENGINEERED ANTHRAX PROTECTIVE ANTIGEN PROTEINS FOR CANCER THERAPY
Engineered anthrax protective antigen (PrAg) proteins are provided wherein the native furin activation site is replaced by the activation site of a...
2018/0214510 NON-IRRITANT OPHTHALMIC COMPOSITION CONTAINING CYCLOSPORIN, AND CONVENIENT PREPARATION METHOD
Provided is an aqueous-medium ophthalmic composition containing: cyclosporin as an active ingredient; and a polyoxyethylene stearate as a solubilizing agent.
2018/0214509 USE OF A BACTERIUM ISOLATED FROM THE GENUS PSEUDOALTEROMONAS, CYCLOLIPOPEPTIDES AND USES THEREOF
The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative,...
2018/0214508 COMPOSITION CONTAINING CYCLIC DIPEPTIDE AND SWEETENING AGENT
Provided a composition excellent in biological safety and capable of enhancing GLP-1 secretion-accelerating effect due to a sweetening agent. The content ratio...
2018/0214507 COMPOSITIONS AND METHODS FOR LONG TERM RELEASE OF GONADOTROPIN-RELEASING HORMONE (GnRH) ANTAGONISTS
The invention provides compositions and methods for long term release of Gonadotropin-releasing hormone (GnRH) antagonists, and uses thereof. Specifically, the...
2018/0214506 COMBINATION ADMINISTRATION OF GNRH ANTAGONISTS
Disclosed herein are methods of administering to a subject a GnRH antagonist with enhanced bioavailability. Also disclosed herein are methods of treating or...
2018/0214505 INFLAMMATION-SUPPRESSING COMPOSITION INCLUDING PEPTIDE
An oligopeptide having a good anti-inflammation effect on microglia has been found, and based on this finding, a composition to be used for suppressing the...
2018/0214504 HEALTH SUPPLEMENT FOOD FOR PROMOTION OF HAIR GROWTH, MITIGATION AND ALLEVIATION OF HAIR LOSS, REGULATION OF...
The present invention relates to a health supplement food. More particularly, the present invention relates to a health supplement food prepared by mixing...
2018/0214503 COMPOSITION FOR WOUND TREATMENT CONTAINING EXTRACT OF STELLERA CHAMAEJASME OR FRACTION THEREOF AND METHOD FOR...
Provided are a composition including Stellera chamaejasme extract for treating wound, a method of treating wound of a subject, a cosmetic composition for wound...
2018/0214502 FORMULATIONS FOR WEIGHT LOSS AND METHODS OF USE
A weight loss composition including banaba leaf extract, apple fruit extract, Rhodiola root extract, zinc chelate, and magnesium chelate are described. The...
2018/0214501 Colloidal suspension for the healing of various cancers
The present invention pertains to a herbal formulation with potent antineoplastic properties, in humans and animals. The composition consists of the powdered...
2018/0214500 BEAUTYBERRY TOTAL GLYCOSIDES EXTRACT AND PREPARATION METHOD AND USE THEREOF
Disclosed is a composition comprising an beautyberry total glycosides extract, and a method of preparation thereof, and the use of the composition thereof in...
2018/0214499 COMPOSITIONS FOR ANTITUSSIVE, EXPECTORANT OR ANTI-INFLAMMATION
The present invention provides a composition containing, as active ingredients, Panax ginseng, Adenophora triphylla, Wolfiporia extensa, Rehmannia glutinosa,...
2018/0214498 METHOD FOR REGULATING, PREVENTING AND/OR TREATING PULMONARY INJURY
A method for regulating, preventing, and/or treating pulmonary injury, and/or for regulating, preventing, and/or treating pulmonary injury-related diseases is...
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