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Patent # Description
2018/0221438 MODULATING URACIL-DNA GLYCOSYLASE AND USES THEREOF
The present invention concerns a method for the prevention and/or treatment of an activation-induced deaminase (AID)-associated disease in a subject in need...
2018/0221437 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MYCOBACTERIUM SPECIES INFECTION AND METHOD USING THE SAME
Provided are a pharmaceutical composition for preventing or treating Mycobacterium sp. infection or a related symptom thereof, wherein the pharmaceutical...
2018/0221436 TREATMENTS OF OXIDATIVE STRESS CONDITIONS
The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the...
2018/0221435 ITCH TREATMENT USING A COMBINATION OF NEUROKININ-1, GASTRIN RELEASING PEPTIDE, AND GLUTAMATE RECEPTOR ANTAGONISTS
Methods, and compositions are provided for inhibition of histamine and non-histamine dependent itch signal transmission or scratch behavior. In one aspect, the...
2018/0221434 Multi-Peptide Composition
The invention relates to a specific peptide combination. The peptide combination may be present in a pharmaceutically acceptable composition. The peptide...
2018/0221433 ANGIOTENSINS IN MUSCULAR DYSTROPHY
The present invention provides, among other things, methods of treating a muscular dystrophy including administering to a subject suffering from or susceptible...
2018/0221432 A drug for the effective control of acute and or chronic pain and a method for its administration
The proposed drug relates to medicine and veterinary applications, in particular, as a means for effective control of acute and/or chronic pain, and may be...
2018/0221431 DIPEPTIDOMIMETICS AS INHIBITORS OF HUMAN IMMUNOPROTEASOMES
The compounds of the present invention are represented by the following compounds having Formula I, where the substituents R1, R4, L, M, X, Y, and s are as...
2018/0221430 FORMULATION CONTAINING AN EXTRACT OF ALPINIA GALANGA, A PROCESS FOR THE PREPARATION THEREOF, AND USES THEREOF
Various embodiments relate to formulations containing an extract of Alpinia galanga; a method of improving cognitive performance by administering an extract of...
2018/0221429 COMPOSITION COMPRISING CAFFEOYLSHIKIMIC ACIDS, PROTOCATECHUIC ACID, HYDROXYTYROSOL, HYDROXYBENZOIC ACID AND...
A composition comprising caffeoylshikimic acids, protocatechuic acid, hydroxytyrosol, hydroxybenzoic acid, said caffeoylshikimic acids and their derivatives...
2018/0221428 Quit Your Itching Cream
The present invention relates to compositions and methods for the treatment of topical skin conditions, comprising of peppermint oil, lavender oil, tea tree...
2018/0221427 TRANSDERMAL FORMULATIONS FOR DELIVERY OF CAPSAICINOIDS
The present application is directed to transdermal formulations comprising one or more capsaicinoinds, one or more 1,4-dialdehyde sesquiterpenes, a penetration...
2018/0221426 Compositions and Methods for Treating and Removing Seborrheic Keratoses
A method of diminishing the appearance of or effecting the removal or disappearance of seborrheic keratoses by the application of compositions containing a)...
2018/0221425 COMPOSITIONS AND METHODS FOR TREATING WOUNDS
Methods and compositions for treating wounds are described. The compositions include core active ingredients derived from the genera of: Calendula, Achillea...
2018/0221424 COMPOSITION FOR PREVENTION OR TREATMENT OF ARTHRITIS, CONTAINING SARGASSUM SERRATIFOLIUM EXTRACT AS ACTIVE...
The present invention relates to a composition for the prevention or treatment of arthritis, the composition containing a Sargassum serratifolium extract as an...
2018/0221423 SYNTHETIC ADENOVIRUSES WITH TROPISM TO DAMAGED TISSUE FOR USE IN PROMOTING WOUND REPAIR AND TISSUE REGENERATION
Synthetic adenoviruses having chimeric fiber proteins and liver detargeting mutations are described. The synthetic adenovirus vectors are capable of...
2018/0221422 STABLE DRY PROBIOTIC COMPOSITIONS FOR SPECIAL DIETARY USES
A dry stable probiotic composition is provided. The composition comprises one or more viable probiotic microorganisms, one or more hydrolyzed proteins, one or...
2018/0221421 COMPOSITIONS COMPRISING BACTERIAL STRAINS
The invention provides compositions comprising one or more bacterial strains for treating or preventing visceral hypersensitivity.
2018/0221420 Method to Suppress the Systemic Toxicity of Chemotherapeutic Drugs
This invention relates to the combination of manuka honey with other chemotherapeutic agents to treat cancer and reduce the toxicity of the treatment. The...
2018/0221419 Methods to Differentiate Stem Cells into Hormone-Producing Cells
Methods are described for differentiating stem and post-natal cells into sex hormone-producing cells that can be administered to a patient autologously or...
2018/0221418 MICRONIZED PLACENTAL TISSUE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
Described herein are compositions composed of micronized placental components, extracts of micronized placental components, and pharmaceutical compositions...
2018/0221417 TREATMENT OF DRY EYE USING AMNION RELEASED FACTORS
Disclosed are means, methods and compositions of matter for treatment of dry eye disease using factors released from placental amniotic tissue when cultured in...
2018/0221416 MUSCULAR DYSTROPHY CHIMERIC CELLS AND METHOD FOR TREATING MUSCULAR DYSTROPHIES
A Muscular Dystrophy Chimeric Cell generated by ex vivo fusion of a myoblast with a second myoblast, mesenchymal stem cell, or stromal cell is described as is...
2018/0221415 SCAFFOLD FOR GROWING NEURONAL CELLS AND TISSUE
The present invention provides a composition based on poly-l-lactic acid (PLLA) acid polylactic-co-glycolic-acid (PLGA) scaffold on which neuronal tissue can...
2018/0221414 EXTRACELLULAR MATRIX FROM PLURIPOTENT CELLS
Isolated extracellular matrix from marrow adherent stromal cells and their descendents, which stimulates the growth and survival of a number of different...
2018/0221413 Glycosaminoglycan Compositions and Methods for Treating Connective Tissue Damage
A pharmaceutical preparation and method for treating connective tissue damage in a mammal comprising administering to a mammal in need thereof a ...
2018/0221412 METHODS AND COMPOSITIONS RELATING TO MESENCHYMAL STEM CELL EXOSOMES
The invention provides compositions comprising mesenchymal stem cell (MSC) derived exosomes, and methods of their use in subjects having certain lung diseases...
2018/0221411 Improved Cell Therapies
The present invention relates to methods for the improved treatment of an inflammatory disorder, where the treatment comprises administration of sex-matched...
2018/0221410 COMBINED ORGAN AND HEMATOPOIETIC CELLS FOR TRANSPLANTATION TOLERANCE OF GRAFTS
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to a recipient, where tolerance to the graft is...
2018/0221409 COMBINED ORGAN AND HEMATOPOIETIC CELLS FOR TRANSPLANTATION TOLERANCE OF GRAFTS
Methods and compositions are provided for combined transplantation of a solid organ and hematopoietic cells to a recipient, where tolerance to the graft is...
2018/0221408 NOVEL CHEWABLE EYE HEALTH FORMULATION
Risk of visual impairment including Age-Related Macular Degeneration (AMD) and cataracts increase with age. This increased risk can be caused by changes in the...
2018/0221407 OPHTHALMIC COMPOSITIONS FOR THERAPEUTIC AND PROPHYLACTIC USES
Disclosed herein are topical ophthalmic compositions comprising ammonium chloride, a quaternary ammonium salt, and stabilized chlorine dioxide. Also disclosed...
2018/0221406 THERAPEUTIC COMBINATIONS OF ANTIVIRAL AND ANTI-INFLAMMATORY THERAPIES
In some embodiments, the invention includes therapeutic combinations of antiviral active pharmaceutical ingredients and anti-inflammatory active pharmaceutical...
2018/0221405 SILICATE CONTAINING COMPOSITIONS AND METHODS OF TREATMENT
The present invention relates to compositions comprising a silicate and methods of use thereof. In particular, the compositions of the present invention are...
2018/0221404 OPHTHALMIC FORMULATIONS COMPRISING COOPERATIVE COMPLEXES OF LOW- AND HIGH-MOLECULAR-WEIGHT HYALURONIC ACID
Disclosed are ophthalmic formulations which use complexes called L/H-HA, obtainable by subjecting at least two fractions of hyaluronic acids and/or other...
2018/0221403 NEW USE OF DEXTRAN SULFATE
The present embodiments relate to the use of dextran sulfate formulated for systemic administration for treatment, inhibition or prevention of cardiac fibrosis...
2018/0221402 METHODS, COMPOSITIONS, AND SYSTEMS FOR DELIVERING THERAPEUTIC AND DIAGNOSTIC AGENTS INTO CELLS
Disclosed are methods for delivering a therapeutic or diagnostic agent to the cytosol of a cell in a subject. The disclosed methods generally include...
2018/0221401 Sterile Formulation Comprising a Stable Phosphorothioate Oligonucleotide
The present invention relates to a composition comprising a phosphorothioate oligonucleotide and at least one fatty acid and/or at least one emulsifying agent,...
2018/0221400 COMPOSITIONS AND METHODS RELATING TO GALECTIN DETECTION
Compositions and methods for detection and assessment of galectins are provided by the present invention, including a labeled compositions, pharmaceutical...
2018/0221399 TLR4 agonists and compositions thereof and their use in the treatment of cancer
Disclosed is a TLR4 agonist alone or in combination with an anti-cancer agent and pharmaceutical compositions thereof, uses thereof, and methods of treatment...
2018/0221398 COMPOSITIONS AND METHODS FOR BOROCARBOHYDRATE COMPLEXES
Borocarbohydrate complex containing compositions are presented that have an improved di-complex to boric acid ratio. In some embodiments, compositions are...
2018/0221397 NOVEL FORMULATIONS AND COMPOSITIONS FOR REJUVENATION OF THE BODY
The present disclosure describes various formulations and compositions for improving one's vitality and health. The formulations may be particularly useful for...
2018/0221396 COMPOSITIONS AND METHODS COMPRISING A PSILOCYBIN DERIVATIVE
This disclosure pertains to new compositions and methods comprising a psilocybin derivative. In one embodiment, the compositions disclosed herein are used for...
2018/0221395 METHODS FOR CANCER AND IMMUNOTHERAPY USING PRODRUGS OF GLUTAMINE ANALOGS
The disclosure provides methods of treating cancer in a subject or preventing a relapse or reducing the incidence of relapse of cancer in a subject in...
2018/0221394 VETERINARY COMPOSITION COMPRISING TORASEMIDE FOR THE TREATMENT OF PULMONARY EDEMA ASSOCIATED WITH HEART...
The invention relates to novel veterinary compositions comprising torasemide or a pharmaceutically acceptable salt thereof and administered in domestic animals...
2018/0221393 CXCR4 BINDING AGENTS FOR TREATMENT OF DISEASES
A method of treating cancer in a subject is disclosed. The method comprises administering to the subject: (i) a therapeutically effective amount of an...
2018/0221392 PAIN-KILLING COMPOSITION COMPRISING A SALICYLIC ACID DERIVATIVE
The subject-matter of the present invention is the use of a therapeutic composition comprising, in an applying carrier, at least one essential oil for...
2018/0221391 SYNTHETIC BILE ACID COMPOSITIONS AND METHODS
Bile acids and related compositions and methods of synthesis and use. More specifically, deoxycholic acid and related compositions, said compositions being...
2018/0221390 Steroid Analogues for Neuroprotection
Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water...
2018/0221389 NATURAL COMBINATION HORMONE REPLACEMENT FORMULATIONS AND THERAPIES
Pharmaceutical compositions for co-administering estradiol and progesterone to a human subject in need thereof are provided. In some embodiments, the...
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