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Patent # Description
2018/0223361 CHARACTERIZATION OF MOLECULES IN NANOFLUIDICS
Methods are provided for detecting and quantitating molecules using fluidics. In preferred embodiments, the methods comprise analyzing blood to detect the...
2018/0223360 METHODS FOR ASSESSING RISK OF DEVELOPING A VIRAL DISEASE USING A GENETIC TEST
This document provides methods and materials related to treating a disease. For example, this document provides methods for treating a subject's disease based...
2018/0223359 CONJUGATED POLYMERIC PARTICLE AND METHOD OF MAKING SAME
A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule...
2018/0223358 STEPWISE SEQUENCING BY NON-LABELED REVERSIBLE TERMINATORS OR NATURAL NUCLEOTIDES
The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible...
2018/0223357 Device Preparation Using Condensed Nucleic Acid Particles
A method of sequencing a nucleic acid strand includes receiving particles having nucleic acid strands coupled to a polymer matrix, exposing the particles to a...
2018/0223356 NANOCHANNEL WITH INTEGRATED TUNNEL GAP
A device for electronic sequencing of polymers consisting of a tunnel gap that is self-aligned with a nanochannel.
2018/0223355 CYCLIC SINGLE MOLECULE SEQUENCING PROCESS
The invention relates to a process for parallel high throughput sequencing of nucleic acid molecules, in particular in the single molecule format.
2018/0223354 NANOFLUIDIC CHANNEL OPENING SIZE CONTROL USING ACTUATION
Apparatus and methods to a DNA sequencing device and related methods that includes a substrate, a nanochannel formed in the substrate, a first electrode, a...
2018/0223353 LOADING MOLECULES INTO SAMPLE WELLS FOR ANALYSIS
Methods of loading a molecule of interest into a sample well are provided. In some aspects, methods of loading a molecule of interest into a sample well...
2018/0223352 RECOMBINANT POLYMERASES FOR INCORPORATION OF PROTEIN SHIELD NUCLEOTIDE ANALOGS
Provided are compositions comprising recombinant DNA polymerases that include amino acid substitutions, insertions, deletions, and/or exogenous features that...
2018/0223351 Nanopore Based Molecular Detection and Sequencing
This disclosure provides systems and methods for molecular identification and polymer (e.g., nucleic acid) sequencing using nanopores. The polymer may be...
2018/0223350 DUPLEX ADAPTERS AND DUPLEX SEQUENCING
This invention pertains to the creation of a complex pool of adapters that contain complementary barcodes to be utilized in next generation sequencing library...
2018/0223349 LIGASE-ASSISTED NUCLEIC ACID CIRCULARIZATION AND AMPLIFICATION
Provided herein are methods for generation and amplification of a single-stranded DNA circle in a single reaction vessel from a linear DNA without any...
2018/0223348 DISTINGUISHING RARE VARIATIONS IN A NUCLEIC ACID SEQUENCE FROM A SAMPLE
The invention generally relates to methods for distinguishing a rare genetic variation in a nucleic acid sequence.
2018/0223347 Oligonucleotide Paints
Novel methods for making high resolution oligonucleotide paints are provided. Novel, high resolution oligonucleotide paints are also provided.
2018/0223346 DNA LIGATION ON RNA TEMPLATE
Disclosed are methods and compositions for detection and amplification of nucleic acids, wherein two DNA strands hybridized to an RNA strand are ligated. In...
2018/0223345 INTEGRATED MULTIPLEX TARGET ANALYSIS
This invention provides biochip cartridges and instrument devices for the detection and/or analysis of target analytes from patient samples.
2018/0223344 COMPOSITIONS AND METHODS FOR ANALYTE DETECTION USING NANOSWITCHES
Provided herein are nucleic acid-based nanoswitches that can detect specific nucleic acids and other analytes types by for example a simple gel electrophoresis...
2018/0223343 Profiling Expression at Transcriptome Scale
Oligonucleotides for detecting and profiling expression products at transcriptome scale.
2018/0223341 Primer Design for Retrieval of Stored Nucleotides
This disclosure describes techniques to improve the accuracy of random access of data stored in polynucleotide sequence data storage systems. Primers used in...
2018/0223340 PRIMER DESIGN FOR RETRIEVAL OF STORED POLYNUCLEOTIDES
This disclosure describes techniques to improve the accuracy of random access of data stored in polynucleotide sequence data storage systems. Primers used in...
2018/0223339 METHODS AND SYSTEMS FOR PHYLOGENETIC ANALYSIS
The present invention discloses methods and systems for designing and using organism-specific and/or operational taxon unit (OTU)-specific probes. The methods...
2018/0223338 MICROBIOME IDENTIFICATION AND USE IN DIAGNOSIS OF HEAD AND NECK SQUAMOUS CELL CANCER
Methods for analyzing the bacterial microbiome of a subject and triaging the subject into treatment for head and neck squamous cell cancer from a saliva or...
2018/0223337 METHODS FOR DETECTING AND TREATING LOW-VIRULENCE INFECTIONS
The invention provides a method for detecting a low-virulence infection in a patient, by distinguishing true infections from false positives. The method...
2018/0223336 GENETIC TESTING FOR PREDICTING RESISTANCE OF MORGANELLA SPECIES AGAINST ANTIMICROBIAL AGENTS
The invention relates to a method of determining an infection of a patient with Morganella species potentially resistant to antimicrobial drug treatment, a...
2018/0223335 REAL-TIME OPTICAL SYSTEM FOR POLYMERASE CHAIN REACTION
An improved device and system for facilitating polymerase chain reaction including a light source, detector, waveguide, and filters that occupy minimal space...
2018/0223334 NOVEL COMPOUNDS FOR USE IN PCR SYSTEMS AND APPLICATIONS THEREOF
This disclosure relates to novel compounds for use in various compositions, kits and methods, including, for example, use in polymerase storage buffers and in...
2018/0223333 Multiplex Amplification Methods
Compositions and methods for amplifying selected polynucleotides, including DNA and RNA, particularly in multiplex amplification reactions using common primers...
2018/0223332 Nucleic Acid Sample Preparation
This invention relates to the preparation of nucleic acid samples for analysis. The invention may be particularly useful for single stranded samples....
2018/0223331 System and Method for Targeted Depletion of Nucleic Acids
The present disclosure provides a system and method for depleting target nucleic acids from a nucleic acid sample. In one aspect, a kit according to the...
2018/0223330 COELENTERAZINE ANALOGUES
Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection...
2018/0223329 CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME
Functionalized chondroitin sulfate, cross-linked polymer matrices comprising functionalized chondroitin sulfate, and methods of making and using the same are...
2018/0223328 COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE FORMYL, SUCCINYL, METHYL SUCCINYL OR MYRISTOYL...
Provided is a compound that comprises the structure: ##STR00001## where SIG is a signaling molecule and R.sup.3 is a formyl, a succinyl, a methyl succinyl, or...
2018/0223327 METHOD FOR DETERMINING ANTIMICROBIAL SUSCEPTIBILITY OF A MICROORGANISM
The present invention provides methods for determining the antimicrobial susceptibility of a microorganism in a clinical sample said method comprising removing...
2018/0223326 Method For Measuring Complement-Dependent Bactericidal Function With Respect To Pneumococci
The present invention relates to a measurement method for complement-dependent bactericidal activity against Streptococcus pneumoniae, and provides a...
2018/0223325 METHODS, APPARATUSES AND SYSTEMS FOR ANALYZING MICROORGANISM STRAINS FROM COMPLEX HETEROGENEOUS COMMUNITIES,...
Methods, apparatuses, and systems for screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying...
2018/0223324 Method for Improving Measurement Accuracy and Devices and Systems Related Thereto
The present disclosure relates to methods and devices for providing accurate measurement of a property of a sample. The method comprises obtaining a plurality...
2018/0223323 ENZYME STABILIZATION IN ELECTROCHEMICAL SENSORS
The present invention relates to a composition for forming an electrode, an electrochemical sensor comprising the same, and a method for determining an analyte...
2018/0223322 Activated Formylglycine-Generating Enzymes and Methods of Producing and Using the Same
The present disclosure provides activated formylglycine-generating enzymes (FGE), methods of producing activated FGE, and their use in methods of producing a...
2018/0223321 METHODS AND COMPOSITIONS FOR SIZE-CONTROLLED HOMOPOLYMER TAILING OF SUBSTRATE POLYNUCLEOTIDES BY A NUCLEIC ACID...
The present invention is directed to methods and compositions for adding tails of specific lengths to a substrate poly--nucleotide. The invention also...
2018/0223320 PROCESSING BIOMASS
Provided herein are methods for processing biomass materials that are disposed in one or more structures or carriers, e.g., a bag, a shell, a net, a membrane,...
2018/0223319 PROTEIN THIOCARBOXYLATE-DEPENDENT L-METHIONINE PRODUCTION BY FERMENTATION
The present invention relates to a recombinant microorganism useful for the production of L-methionine and process for the preparation of L-methionine. The...
2018/0223318 METHOD FOR PRODUCING alpha-HYDROMUCONIC ACID
A method of producing .alpha.-hydromuconic acid using a metabolic pathway of a microorganism is disclosed. The method of producing .alpha.-hydromuconic acid...
2018/0223317 METHODS AND SYSTEMS FOR CHEMOAUTOTROPHIC PRODUCTION OF ORGANIC COMPOUNDS
The present disclosure identifies pathways, mechanisms, systems and methods to confer chemoautotrophic production of carbon-based products of interest, such as...
2018/0223316 COMPOSITIONS AND METHODS FOR IDENTIFYING AND MODIFYING CARBONACEOUS COMPOSITIONS
This invention generally relates to natural gas and methylotrophic energy generation, bio-generated fuels and microbiology. In alternative embodiments, the...
2018/0223315 THERAPEUTIC SERUM OBTAINED FROM CO-CULTURED CELLS
A therapeutic serum suitable for inclusion in a cosmetic preparation may be produced by stressing a co-culture including proliferative cells. The co-culture of...
2018/0223314 POTENT AND SHORT PROMOTER FOR EXPRESSION OF HETEROLOGOUS GENES
The invention provides an AoHV-1 promoter for use with plasmid vectors, viral vectors, viruses, and cell lines comprising the AoHV-1 promoter operably linked...
2018/0223313 LENTIVIRAL PROTEIN DELIVERY SYSTEM FOR RNA-GUIDED GENOME EDITING
The invention is directed to a system comprising a lentivirus vector particle which encodes at least one guide RNA sequence that is complementary to a first...
2018/0223312 CAPSID-MODIFIED, RAAV3 VECTOR COMPOSITIONS AND USES IN GENE THERAPY OF HUMAN LIVER CANCER
Disclosed are next-generation multi-mutated capsid protein-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical...
2018/0223311 METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION
Methods and compositions for a genetic disease are provided.
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