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Patent # Description
2018/0223310 Methods and Materials for Conferring Resistance to Pests and Pathogens of Plants
Methods and materials for conferring pest resistance to plants are provided. Plants are transformed with a silencing construct homologous to a gene of a plant...
2018/0223309 COPI COATOMER GAMMA SUBUNIT NUCLEIC ACID MOLECULES THAT CONFER RESISTANCE TO COLEOPTERAN AND HEMIPTERAN PESTS
This disclosure concerns nucleic acid molecules and methods of use thereof for control of insect pests through RNA interference-mediated inhibition of target...
2018/0223308 RAB5 NUCLEIC ACID MOLECULES THAT CONFER RESISTANCE TO COLEOPTERAN AND HEMIPTERAN PESTS
This disclosed subject matter concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated...
2018/0223307 COPY NUMBER VARIANT LEADING TO VIRUS RESISTANCE
The present invention relates to a genetic determinant which may comprise at least two copies of a combination of two closely linked RDR1 genes, which two...
2018/0223306 ARTIFICIAL SALT TOLERANT PROTEIN, ITS SYNTHETIC METHOD AND CODING GENE THEREOF AND USE OF SAID CODING GENE
This invention relates to an artificial salt tolerant protein NLEA with the amino acid sequence shown in SEQ ID No.1 and a synthetic method of salt tolerant...
2018/0223305 TRANSGENIC PLANTS HAVING INCREASED TOLERANCE TO ALUMINUM
Methods and materials for modulating aluminum tolerance in plants are disclosed. For example, nucleic acids encoding aluminum tolerance-modulating polypeptides...
2018/0223304 TRANSGENIC PLANTS HAVING INCREASED TOLERANCE TO ALUMINUM
Methods and materials for modulating aluminum tolerance in plants are disclosed. For example, nucleic acids encoding aluminum tolerance-modulating polypeptides...
2018/0223303 SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY
The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful...
2018/0223302 CARBON-NEUTRAL AND CARBON-POSITIVE PHOTORESPIRATION BYPASS ROUTES SUPPORTING HIGHER PHOTOSYNTHETIC RATE AND YIELD
The present invention relates to an organism, a tissue, a cell or an organelle expressing enzymes which allow the conversion of 2-phosphoglycolate (2-PG; also...
2018/0223301 OVEREXPRESSION OF PLANT GENES INVOLVED IN PROGRAMMED CELL DEATH FOR YIELD INCREASE
The present invention relates to a transgenic expression construct for plants, comprising an anti-apoptotic gene of the BAG family of plant genes and a...
2018/0223300 Methods and Materials for Producing Fruit of Altered Size
The invention provides materials and methods for producing fruit of altered size, or plants that produce fruit of altered size, by altering expression of...
2018/0223299 Method of Producing Lipid
A method of improving lipid productivity, containing the steps of: enhancing the expression of a gene encoding the following protein (A) or (B), and improving...
2018/0223298 TOUCH PANEL AND IMAGE DISPLAY DEVICE HAVING THE SAME
A touch panel may include: a sensing electrode part including a plurality of first sensing electrodes and a plurality of second sensing electrodes insulated...
2018/0223297 FAD2 PERFORMANCE LOCI AND CORRESPONDING TARGET SITE SPECIFIC BINDING PROTEINS CAPABLE OF INDUCING TARGETED BREAKS
A method of gene editing or gene stacking within a FAD2 loci by cleaving, in a site directed manner, a location in a FAD2 gene in a cell, to generate a break...
2018/0223296 METHOD FOR MODULATING EXPRESSION OF SPECIFIC PROTEIN USING SPECIFIC TRANSCRIPTION FACTOR, ISOPRENOID-PRODUCING...
The present invention provides methods for enhancing the polyisoprenoid biosynthesis pathway. The present invention further provides isoprenoid-producing...
2018/0223295 METHODS AND HYBRIDS FOR TARGETED NUCLEIC ACID EDITING IN PLANTS
The present invention relates to methods and hybrids for the targeted modification of a nucleic acid-target region in a plant target structure. The invention...
2018/0223294 PLANTS COMPRISING A LOW COPY NUMBER OF RI GENES
Described is a plant transformed with one or more genes originating from the Ri plasmid of Agrobacterium rhizogenes by infection with A. rhizogenes comprising...
2018/0223293 Promoter Variants
An isolated and/or artificial pG1-x promoter, which is a functional variant of the carbon source regulatable pG1 promoter of Pichia pastoris identified by SEQ...
2018/0223292 Novel Promoter
Provided is a promoter suitable for the high expression of a gene of interest. A promoter consisting of a DNA selected from the group consisting of the...
2018/0223291 BACTERIOPHAGE RECOMBINATION FOLLOWED BY BLOCKAGE OF NON-RECOMBINANT BACTERIOPHAGE REPLICATION
The present disclosure provides methods and kits for generating recombinant bacteriophage genomes. Specifically, the present technology provides methods of...
2018/0223290 METHOD FOR PROPAGATING ADENOVIRAL VECTORS ENCODING INHIBITORY GENE PRODUCTS
The invention provides a method of propagating an adenoviral vector. The method comprises (a) providing a cell comprising a cellular genome comprising a...
2018/0223289 MODULATION OF TMPRSS6 EXPRESSION
Disclosed herein are antisense compounds and methods for modulating TMPRSS6 and modulating an iron accumulation disease, disorder and/or condition in an...
2018/0223288 COMPOSITIONS AND METHODS FOR THE MODULATION OF DNA DAMAGE RESPONSES USING BAL1 AND BBAP
The invention provides methods and compositions for enhancing the efficacy of cancer therapies through modulation of BAL1 and/or BBAP. Also provided are...
2018/0223287 FIBROTIC TREATMENT
The present invention relates to a method for the treatment of fibrosis, in particular cardiac fibrosis, comprising the administration of an inhibitor of...
2018/0223286 INTERFERING RNA MOLECULES
The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand...
2018/0223285 C5a Binding Nucleic Acids
The present invention is related to a nucleic acid molecule capable of binding to human C5a, wherein the nucleic acid molecule comprises a central stretch of...
2018/0223284 MULTIMERIC OLIGONUCLEOTIDES HAVING DECREASED KIDNEY CLEARANCE
The present invention relates to methods of administering to a subject multimeric oligonucleotides having monomeric subunits joined by linkers. The multimeric...
2018/0223283 ANTISENSE FINGERLOOP RNAS AND USES THEREOF
The present disclosure relates to chimeric antisense nucleotides and methods for modulating protein expression levels and/or RNA stability from at least two...
2018/0223282 COMPOSITIONS AND METHODS FOR MODULATING MECP2 EXPRESSION
Aspects of the invention provide single stranded oligonucleotides for activating or enhancing expression of MECP2. Further aspects provide compositions and...
2018/0223281 STRUCTURALLY-ENHANCED miRNA INHIBITOR S-TuD
The present invention pertains to the improvement of a miRNA inhibitor (a synthesized Tough Decoy (S-TuD)). The present invention provides a miRNA inhibitory...
2018/0223280 NUCLEIC ACID COMPLEX
Provided is a nucleic acid complex, preferably a double-stranded nucleic acid complex, having an excellent effect of suppressing the expression of a target...
2018/0223279 THERAPEUTIC OLIGONUCLEOTIDES
The present invention relates to an oligonucleotide comprising one of the following sequence: (TTAGGG) SEQ ID No. 1, (TAGGGT) SEQ ID No. 2, (AGGGTT) SEQ ID No....
2018/0223278 Functionally-Modified Oligonucleotides And Subunits Thereof
Functionally-modified oligonucleotide analogues comprising modified intersubunit linkages and/or modified 3' and/or 5'-end groups are provided. The disclosed...
2018/0223277 NEW PRECURSOR MIRNA AND APPLICATIONS IN TUMOR THERAPY THEREOF
Provided are a new precursor miRNA and the applications in tumor therapy thereof. The precursor miRNA, from 5'- to 3'-end thereof, has the structure...
2018/0223276 Methods and Compositions for Preventing Concatemerization During Template-Switching
Compositions and methods for performing a template-switching reaction are provided that may include reducing or eliminating concatemerization of the...
2018/0223275 METHODS AND MATERIALS FOR CLONING FUNCTIONAL T CELL RECEPTORS FROM SINGLE T CELLS
This document provides methods and materials involved in cloning functional TCRs from single T cells. For example, methods and materials for obtaining nucleic...
2018/0223274 Molecular Sensor Selection
Provided herein, among other things, is an automatable procedure that employs in vitro directed evolution to create DNA sequences that encode a ...
2018/0223273 Therapeutic Cell Washing, Concentration, and Separation Utilizing Acoustophoresis
Multi-stage acoustophoretic devices for continuously separating a second fluid or a particulate from a host fluid are disclosed. Methods of operating the...
2018/0223272 METHOD AND DEVICE FOR NON-THERMAL EXTRACTION OF PHYTOCHEMICALS FROM MACROALGAE
A method is for the extraction of a phytochemical, e.g., peptide or protein, or a chemical element from a macroalgae, by applying pulsed electric field (PEF)-...
2018/0223271 XYLOSE ISOMERASE-MODIFIED YEAST STRAINS AND METHODS FOR BIOPRODUCT PRODUCTION
The present invention relates to a genetically engineered yeast (e.g., Crabtree negative) that express a heterologous xylose isomerase. In a fermentation...
2018/0223270 A NOVEL PURIFICATION PROCESS FOR ISOLATION AND COMMERCIAL PRODUCTION OF RECOMBINANT TNK-TPA TENECTEPLASE
The present invention relates to a novel process of isolating and purifying tissue plasminogen activator and its variants more specifically TNK-tPA from CHO...
2018/0223269 COMPOSITIONS AND METHODS COMPRISING VARIANT MICROBIAL PROTEASES
The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using...
2018/0223268 Polypeptides Having Cellobiohydrolase Activity And Polynucleotides Encoding Same
Disclosed herein are polypeptides having cellobiohydrolase activity, catalytic domains, carbohydrate binding modules and polynucleotides encoding the...
2018/0223267 POLYNUCLEOTIDES ENCODING MUTANT HYDROLASE PROTEINS WITH ENHANCED KINETICS AND FUNCTIONAL EXPRESSION
The invention provides a mutant hydrolase protein with enhanced kinetics and functional expression, as well as polynucleotides encoding the mutant proteins and...
2018/0223266 HIV KINASE VARIANTS
Described are HIV kinase variants showing an improved activity in converting 3-hydroxyisovalerate (HIV) into 3-phosphonoxyisovalerate (PIV), methods for the...
2018/0223265 ENGINEERED TRANSAMINASE POLYPEPTIDES FOR INDUSTRIAL BIOCATALYSIS
The present disclosure provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions....
2018/0223264 ENGINEERED GLYCOSYLTRANSFERASES AND STEVIOL GLYCOSIDE GLUCOSYLATION METHODS
The present invention provides engineered glycosyltransferase (GT) enzymes, polypeptides having GT activity, and polynucleotides encoding these enzymes, as...
2018/0223263 AGGREGATE-FREE URATE OXIDASE FOR PREPARATION OF NON-IMMUNOGENIC POLYMER CONJUGATES
A naturally occurring or recombinant protein, especially a mutein of porcine urate oxidase (uricase), that is essentially free of large aggregates can be...
2018/0223262 RECOMBINANT K1-5 BACTERIOPHAGES AND USES THEREOF
The present disclosure provides compositions including recombinant K1-5 bacteriophages, methods for making the same, and uses thereof. The recombinant K1-5...
2018/0223261 ATTENUATED INFLUENZA VACCINES AND USES THEREOF
Provided herein are attenuated influenza viruses and methods of making attenuated influenza viruses.
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