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Patent # Description
2018/0237390 IMPROVED PROCESS FOR THE PREPARATION OF APREMILAST
The present invention relates to novel processes for the preparation of apremilast of formula I, or a pharmaceutically acceptable salt thereof. ##STR00001##
2018/0237389 METHOD OF PRODUCING EPSILON-CAPROLACTAM
A method of producing .epsilon.-caprolactam from 3-oxoadipic acid includes: step 1 of mixing at least one selected from the group consisting of 3-oxoadipic...
2018/0237388 PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYCOXYLIC ACID
A process for the synthesis of lactams suitable for use in antimicrobial, anti-biofilm bacteriostatic compositions.
2018/0237387 CERAMIDE DIMER, METHOD FOR THE PRODUCTION THEREOF, AND USE OF SAME
The invention relates to ceramide dimers in which the amino alcohols are linked together by amide bonds via a dicarboxylic acid. The dicarboxylic acids have at...
2018/0237386 Process For Preparation Of Vortioxetine Hydrobromide
The present invention provides a process for preparation of Vortioxetine hydrobromide (I). The present invention also relates to the novel intermediate and its...
2018/0237385 AGONISTS OF PROTEIN TYROSINE PHOSPHATASE SHP-1
Some novel compounds are provided in this disclosure. These novel compounds have potential SHP-1 agonist activity for being used in treating cancer.
2018/0237384 3-PHENYLISOSERINE DERIVATIVE PRODUCTION METHOD
A method produces a 3-phenylisoserine derivative by protecting an amino group of a compound represented by General Formula (1) (wherein R.sup.1 represents a...
2018/0237383 NATURAL PRODUCT ANALOGS INCLUDING AN ANTI-INFLAMMATORY CYANOENONE PHARMACORE AND METHODS OF USE
This invention provides novel compounds comprising the following anti-inflammatory pharmacore: ##STR00001## wherein X, R.sub.1 and R.sub.2 are defined herein....
2018/0237382 NOVEL CARBOCYCLIC COMPOUNDS AS ROR GAMMA MODULATORS
The present disclosure is directed to novel carbocyclic compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2,...
2018/0237381 COMPOSITION AND METHODS OF USE OF NOVEL PHENYLALANINE SMALL ORGANIC COMPOUNDS TO DIRECTLY MODULATE PCSK9...
This invention is related to the field of PCSK9 biology and the composition and methods of use of small organic compounds as ligands for modulation of PCSK9...
2018/0237380 IMMUNOASSAY
Antibodies, immunoassay methods and kits for the detection and determination of 3,4,-dichloro-N-[2-(dimethylamino)cylohexyl]-N-methylbenzamide and ...
2018/0237379 SUBSTITUTED MALONAMIDES AND THEIR USE AS ANTIBACTERIAL DRUGS
Disclosed are a series of malonamide derivatives having a chemical structure(I), their synthesis, and evaluation of their bioactivities against bacterial cell,...
2018/0237378 Asymmetric Bisamidation of Malonic Ester Derivatives
The present invention relates to processes, process steps and intermediates useful in the asymmetric bisamidation of malonic ester derivatives wherein the new...
2018/0237377 Process for the Synthesis of Melphalan and the Hydrochloride Salt
The present invention relates to an improved process for the preparation of Melphalan, more specifically the invention relates to an efficient process for the...
2018/0237376 METHOD FOR PREPARING ARYL SUBSTITUTED P-PHENYLENEDIAMINE SUBSTANCE
A method for preparing an aryl substituted p-phenylenediamine substance is provided. A structural formula of the aryl substituted p-phenylenediamine substance...
2018/0237375 METAL COMPOUNDS OF CALIXARENES, DETERGENT COMPOSITIONS CONTAINING THEM AND USE THEREOF IN LUBRICANT COMPOSITIONS
The present invention relates to a metal compound of calixarene not containing sulfur and dispersible in oil, which can be partially salified, or neutral, or...
2018/0237374 Substituted Aromatic Compounds and Related Method for the Treatment of Fibrosis
The present invention relates to compounds of: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein A is C.sub.5 alkyl, C.sub.6 alkyl, C.sub.5...
2018/0237373 METHOD OF DETERMINING THE INERTNESS OF MATERIALS FOR USE IN MONOMER PRODUCTION
A method of determining the inertness of a material regarding the formation of heavy by-products during the reaction of propylene to acrolein and acrylic acid.
2018/0237372 METHOD FOR PRODUCING ACRYLIC ACID
A method for preparing acrylic acid, more specifically, to a method for preparing acrylic acid under a neutral condition at high yield in a short time without...
2018/0237371 METHOD OF CATALYTIC OXIDATION OF LIGNITE USING OXYGEN AS OXIDANT AT ATMOSPHERIC PRESSURE
Disclosed is a method of catalytic oxidation of lignite using oxygen as an oxidant at atmospheric pressure, belonging to a method of mild oxidation of lignite....
2018/0237370 GREEN METHOD FOR COATING A SUBSTRATE WITH SILVER NANOPARTICLES
The method for coating a substrate with silver nanoparticles includes reducing a silver nitrate solution with an ethanol extract of the traditional Indian...
2018/0237369 PROCESS FOR PREPARING 1,4-BIS(ETHOXYMETHYL)CYCLOHEXANE
The present invention relates to a process for preparing,4-bis(ethoxymethyl)cyclohexane, which comprises reacting1,4-bis(hydroxymethyl)cyclohexane with ethyl...
2018/0237368 CANNABIDIOL EXTRACTION AND CONVERSION PROCESS
A cannabidiol extraction and conversion process includes an extraction process including a sizing unit wherein raw Cannabis plant material is reduced to a...
2018/0237367 PROCESS AND SYSTEMS FOR OBTAINING 1,4-BUTANEDIOL FROM FERMENTATION BROTHS
A process of purifying 1,4-butanediol (1,4-BDO) from a fermentation broth including separating solid materials, salts and water, and subjecting the resulting...
2018/0237366 NOVEL PROCESS FOR METHANOL PRODUCTION FROM LOW QUALITY SYNTHESIS GAS
In a novel process for methanol production from low quality synthesis gas, in which relatively smaller adiabatic reactors can be operated more efficiently,...
2018/0237365 METHOD FOR PRODUCING HALOOLEFIN COMPOUND AND METHOD FOR REMOVING STABILIZER
The present invention provides a method for producing a fluorine-containing haloolefin compound, the method easily inhibiting catalyst deactivation, and the...
2018/0237364 CATALYTIC CHLORINATION OF 3,3,3-TRIFLUOROPROPENE TO 2,3-DICHLORO-1,1,1-TRIFLUOROPROPANE
The present invention relates to a process for preparing 1,1,1-trifluoro-2,3-dichloropropane which comprises contacting chlorine with 3,3,3-trifluoropropene in...
2018/0237363 METHOD FOR COUPLING AN AROMATIC COMPOUND TO AN ALKYNE
In one aspect, there is provided a method of coupling an aromatic compound having a fluorosulfonate substituent to an alkyne. In another aspect, there is...
2018/0237362 NOVEL POLYGODIAL ANALOGS FOR THE TREATMENT OF CANCER AND OTHER PROLIFERATIVE DISEASES
The present disclosure relates generally to derivatives of polygodial and methods of use thereof. In some aspects, the present disclosure relates to using...
2018/0237361 Aromatic Compositions and Methods for Obtaining Them
Aromatic compositions useful in various applications, such as aromatic fluid solvents and high temperature heat transfer fluids, are provided herein. Also...
2018/0237360 SELECTIVE OLIGOMERIZATION REACTION PROCESS OF ETHYLENE
The present invention relates to a commercial reaction process for the selective oligomerization reaction of ethylene, and a method for efficiently removing...
2018/0237359 HYBRID CHEM-BIO METHOD TO PRODUCE DIENE MOLECULES
A method 100 to produce one or more diene molecules 135 including steps of preparing a biomass hydrolysate 137 from biomass, producing an engineered organism...
2018/0237358 RADIOISOTOPE 18F SUBSTITUTED THIAMINE, AND SYNTHESIS METHOD AND USE THEREOF
The present invention discloses a radioisotope .sup.18F substituted thiamine, synthesis method, and use thereof in small animal PET/CT imaging. The...
2018/0237357 CROWD DISPERSING COMPOSITION
A crowd dispersing composition includes a mixture including limburger cheese, rotten eggs, sulfur compounds having a smell of rotten food, rotten fish and...
2018/0237356 GRANULAR FERTILIZERS COMPRISING MACRONUTRIENTS AND MICRONUTRIENTS, AND PROCESSES FOR MANUFACTURE THEREOF
Novel granular fertilizers and methods of making those fertilizers are provided. The method utilized involves recycling streams, including one that provides...
2018/0237355 MULTI-NUTRIENT GRANULAR FERTILIZER COMPOSITIONS AND METHODS OF USING THE SAME
Granular fertilizer compositions are described herein that are capable of supplying a wide array of beneficial nutrient and compounds to soil for uptake by the...
2018/0237354 COMPETITIVE AND EFFECTIVE BACTERIAL STRAINS
According to the present invention new isolates of bacterial strains have been shown to possess unique properties. These bacterial strains are plant...
2018/0237353 MICROBIAL CONSORTIA
Disclosed herein are microbial consortia and compositions including microbes, for example, for use in agricultural or biodegradation applications. In some...
2018/0237352 SOLUBLE FERTILIZER FORMULATION AND METHOD FOR USE THEREOF
A fertilizer including a growth enhancing component, in at least one example a co-polymer of fulvic acid and poly-metallic humates is present in the amount of...
2018/0237351 GRANULAR FERTILIZERS COMPRISING MACRONUTRIENTS AND MICRONUTRIENTS, AND PROCESSES FOR MANUFACTURE THEREOF
Novel granular fertilizers and methods of making those fertilizers are provided. The method utilized involves recycling streams, including one that provides...
2018/0237350 ARTIFICIAL SOILS AND METHODS FOR MANUFACTURING ARTIFICIAL SOILS
An artificial soil for growing vegetation includes a mixture of biosolids from a wastewater treatment plant, at least one of synthetic gypsum and a ...
2018/0237349 METHOD OF PRODUCTION OF EDGE PROTECTION STRIPS OF CERAMIC MATERIAL
A method of production of edge protection strips (10) of ceramic material, includes the steps of: arranging a sheet-like article (20) of ceramic material...
2018/0237348 CERAMIC BONDED BODY
A ceramic bonded body of the disclosure includes a first silicon carbide ceramics, a second silicon carbide ceramics, and a bonding layer positioned between...
2018/0237347 SILICON NITRIDE SINTERED BODY WITH HIGH THERMAL CONDUCTIVITY AND METHOD FOR MANUFACTURING SAME
Embodiments relate to a method for manufacturing a silicon nitride sintered body with high thermal conductivity, which includes the steps of: a) obtaining a...
2018/0237346 METHOD OF PRODUCING A COMPONENT OF A COMPOSITE OF DIAMOND AND A BINDER
A method of producing a component of a composite of diamond and a binder, wherein a Hot Isostatic gas Pressure process (HIP) is used, includes the step of...
2018/0237345 Shaded Zirconia Ceramic Material and Machinable Sintered Ceramic Bodies Made Therefrom
Shaded, zirconia ceramic materials are disclosed that are suitable for use in dental applications. Ceramic bodies are made from a zirconia-containing ceramic...
2018/0237344 UNSHAPED PRODUCT FOR REPAIRING GLASS MELTING FURNACES
An unshaped product including, as weight percentages, A) particles (a) of at least one refractory material other than a glass and a glass-ceramic, and the main...
2018/0237343 METHOD FOR PRODUCING ORIENTED SINTERED BODY
A method for producing an oriented sintered body according to the present invention includes the steps of: (a) preparing a multilayer body, the multilayer body...
2018/0237342 Binder Composition For Use With Aggregates
A binder composition substantially comprising between 68.7 and 93% by weight cement, between 0 and 20% by weight additional silicate bearing material, and...
2018/0237341 ULTRA-LIGHT CEMENTITIOUS COMPOSITIONS AND RELATED METHODS
An ultra-light, pourable, self-drying cementitious product with improved density control and ultra-low water demand is provided. Compositions and methods for...
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