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Patent # Description
2018/0243391 VACCINATIONS AGAINST LYME DISEASE
The presently disclosed subject matter relates to vaccinations against Lyme disease, in particular vaccinations including one or more isolated polypeptides of...
2018/0243390 INFLAMMASOME ACTIVATORS AND METHODS OF USE TO TREAT TUMORS
Compositions and treatments for inducing tumor regression by activating inflammasomes in tumor cells and tumor-associated cells. A tumor in a subject is...
2018/0243389 FUSION PROTEINS COMPRISING MODIFIED ALPHA VIRUS SURFACE GLYCOPROTEINS AND TUMOR ASSOCIATED ANTIGEN AND METHODS...
The present disclosure relates to fusion proteins that comprise one or more modified alpha virus surface glycoproteins and one or more tumor specific antigens....
2018/0243388 COMPOSITIONS AND METHODS FOR TREATING MELANOMA
Melanoma vaccines are provided. Compositions and methods are provided for making and using melanoma vaccine constructs, alone, or in combination with at least...
2018/0243387 TECHNOLOGY FOR CONTROLLING IMMUNE CELLS
The invention provides compositions or pharmaceutical compositions for use in inducing acquired immune lymphocytes to produce type I interferons, inhibiting...
2018/0243386 IDENTIFICATION OF CD8+ T CELLS THAT ARE CD161HI AND/OR IL18R(ALPHA)HI AND HAVE RAPID DRUG EFFLUX CAPACITY
This invention provides, among other things, methods for the identification and isolation of viable putative long-lived antigen-specific memory CD8.sup.+ T...
2018/0243385 METHODS FOR INDUCING SELECTIVE APOPTOSIS
Provided herein are methods for cell therapy by modifying transfused cells to express an inducible caspase 9 protein, so that the cells may be selectively...
2018/0243384 METHODS FOR INDUCING PARTIAL APOPTOSIS USING CASPASE POLYPEPTIDES
The technology relates in part to methods for inducing partial apoptosis of cells that express an inducible caspase polypeptide. The technology further relates...
2018/0243383 USE OF APC ANALOGUE FOR WOUND HEALING
The invention relates to wound repair and healing, particularly to dermal or cutaneous wounds including but not limited to acute and chronic wounds, burns and...
2018/0243382 TARGETING MDA-5 ACTIVATION FOR CANCER IMMUNOTHERAPY
Provided herein are methods and pharmaceutical compositions for treating cancer, such as prostate cancer. More specifically, MDA-5-encoding polynucleotides or...
2018/0243381 Formation of Bone
Compositions and methods for inducing or promoting repair of a bone fracture.
2018/0243380 RAPID ACTION INSULIN FORMULATIONS AND PHARMACEUTICAL DELIVERY SYSTEMS
The present invention provides rapid-acting insulin and insulin analogue formulations. The invention further provides delivery devices, particularly infusion...
2018/0243379 Treatment of Type 2 Diabetes Mellitus Patients
The present invention refers to lixisenatide for use in the reduction of progression of urinary albumin excretion in a type 2 diabetes mellitus patient.
2018/0243378 TREATING CARDIOVASCULAR OR RENAL DISEASES
This document provides methods and materials for treating cardiovascular and/or renal diseases. For example, AAV9 vectors designed to express natriuretic...
2018/0243377 IFN-ALPHA/BETA-INDEPENDENT MECHANISM OF ANTIVIRAL PROTECTION THROUGH A NOVEL LIGAND-RECEPTOR PAIR: IFN-LAMBDA...
A novel IFN-.alpha./ independent ligand receptor system which upon engagement leads, among other things, to the establishment of an anti-viral state is...
2018/0243376 METHODS AND NON-IMMUNOGENIC COMPOSITIONS FOR TREATING INFLAMMATORY DISORDERS
Methods for making non-immunogenic anti-inflammatory cytokine compositions, comprising (a) obtaining a liquid comprising cytokine producing cells from a...
2018/0243375 Modified FGF-21 Polypeptides and Uses Thereof
Modified FGF-21 polypeptides and uses thereof are provided, for example, for the treatment of diseases associated with fibrosis. Modified FGF-21 polypeptides...
2018/0243374 COMPOSITION FOR DIAGNOSING, PREVENTING, OR TREATING VASCULAR SMOOTH MUSCLE CELL PROLIFERATIVE DISEASES USING FGF12
The present invention directs to a method for treating a smooth muscle cell proliferative disease by using a recombinant expression vector comprising a...
2018/0243373 TOPICAL ERYTHROPOIETIN FORMULATIONS AND METHODS FOR IMPROVING WOUND HEALING WITH AND COSMETIC USE OF THE...
Topical formulations containing erythropoietin (EPO), and also preferably fibronectin (FN), especially gel formulations, are used to accelerate wound healing,...
2018/0243372 B7-H1 Fusion Polypeptides for Treating and Preventing Organ Failure
The present invention pertains to a fusion polypeptide for use in treating and/or preventing organ failure in a subject suffering from sepsis, said fusion...
2018/0243371 MUSSEL ADHESIVE PROTEIN PRODUCT AND USE THEREOF FOR TREATING MUCOSAL INFLAMMATION
The invention relates to a mussel adhesive protein (MAP) and an application thereof in inhibiting catarrh, and specifically, to applications of a MAP or a...
2018/0243370 METHODS AND COMPOSITIONS FOR TREATMENT OF GAUCHER DISEASE VIA MODULATION OF C5A RECEPTOR
Disclosed are compositions and methods for the reduction of C5a mediated immune inflammation. The methods, in various aspects, may include the step of...
2018/0243369 ALPHA-1-MICROGLOBULIN FOR USE IN THE PROTECTION OF KIDNEYS IN RADIONUCLIDE THERAPY
This invention relates to .alpha..sub.1-microglobulin (A1M) for use in the diagnosis or treatment of malignancies requiring radionuclide diagnostics (RD),...
2018/0243368 MOLECULAR SIGNATURE OF CANCER
The present invention provides compounds, compositions, and methods for detecting, diagnosing and treating cancers such as glioblastoma multiforme.
2018/0243367 Inhibitor of IGFBP3/TMEM219 Axis and Diabetes
The present invention relates to the role of the IGFBP3/TMEM219 axis in the onset of diabetes and the related use of IGFBP3/TMEM219 axis inhibitors for the...
2018/0243366 DRUG CONTAINING RECOMBINANT MISTLETOE LECTINS FOR TREATING MALIGNANT MELANOMA
The invention relates to a drug and/or pharmaceutical composition for treating metastatic tumors, in particular of malignant melanoma, above all of stage IV...
2018/0243365 PEPTIDE INHIBITORS OF CLOSTRIDIUM DIFFICILE TCDB TOXIN
Disclosed are synthetic peptides and peptide compositions, including peptide conjugates, that can ameliorate and/or block the cytotoxicity of C. difficile TcdB...
2018/0243364 MODULATION OF TUMOR IMMUNITY BY PROTEIN-MEDIATED 02 DELIVERY
The invention provides methods to modulate hypoxia-mediated tumor immunity by administration of an O.sub.2 carrier polypeptide (e.g., an H-NOX protein). The...
2018/0243363 NEUROKININ 1 RECEPTOR AGONIST MEDIATED PROTECTION OF THE EYE
Neurokinin 1 receptor (NK1R) agonist mediated protection of the eye is described. The protection can reduce dry eye and ocular infections, particularly in...
2018/0243362 METHOD FOR PRODUCING DRY EXTRACTS
The invention relates to a method for producing dry extracts of plants and to pharmaceutical preparations containing the same, more particularly ...
2018/0243361 COMPOSITION COMPRISING NATURAL COMPLEX EXTRACT AS ACTIVE INGREDIENT
The present invention relates to a composition comprising a natural complex extract. It is confirmed that the composition has synergistic effects on...
2018/0243360 ANTI-FATIGUE COMPOSITION USED FOR INCREASING ENDURANCE PERFORMANCE, AND USE OF THE SAME
A composition and its use in anti-fatigue are provided, wherein the composition comprises a first component being a Cistanche tubulosa extract and a second...
2018/0243359 SYNERGISTIC ANTIBACTERIAL EFFECTS OF MAGNOLIA BARK EXTRACT AND L-ARGININE, N-ALPHA-LAUROYL ETHYL ESTER ON...
The present disclosure relates generally to oral compositions and methods for inhibiting the formation of plaque biofilm by salivary bacteria, and more...
2018/0243358 COMPOSITION CONTAINING ANGELICA EXTRACT FOR PROMOTING PROLIFERATION OF STEM CELLS DERIVED FROM BONE MARROW
The present invention relates to a composition for promoting proliferation of bone marrow derived stem cells using an angelicae gigantis radix extract, and...
2018/0243357 COMBINED COMPOSITIONS FOR CONTROLLING BLOOD SUGAR LEVELS, HEPATOPROTECTION, AND FOR PREVENTION AND TREATMENT OF...
The invention relates to compositions and methods using various combinations of at least one of phytosterols, lunasin peptide and plant extracts, optionally in...
2018/0243356 INTEGRATIVE FUNGAL SOLUTIONS FOR PROTECTING BEES
The present invention is based on a plurality of benefits from the extracts of mycelia of individual fungal species, and mixtures of species, to provide an...
2018/0243355 ANTI-CANCER AGENT COMPRISING HVJ-E AND CXCL2
The present invention provides, as a new anti-cancer agent obtained by combining HVJ-E and a molecule synergistically acting therewith, an anti-cancer agent...
2018/0243354 PROCESS FOR THE MANUFACTURE OF PATHOGEN INHIBITING BACTERIA
Processes to produce microorganisms that can be incorporated into a microbial-based product that results in high viable cell yields and shelf-stable products...
2018/0243353 COMPOSITION AND METHOD FOR TREATMENT AND PROPHYLAXIS OF INTESTINAL INFECTION AND INFLAMMATION
The present invention relates to a composition for use in the treatment and/or prevention of a gastrointestinal condition, comprising at least one...
2018/0243352 LACTIC ACID BACTERIA, NATURAL IMMUNOACTIVATOR AND INFECTION PREVENTATIVE/THERAPEUTIC DERIVED FROM SAID LACTIC...
Lactic acid bacteria having high natural immunity activation ability and infection preventative/therapeutic containing said lactic acid bacteria or elements...
2018/0243351 BACTERIOTHERAPY FOR CLOSTRIDIUM DIFFICILE COLITIS
This document discusses, among other things, receiving a plurality of donor fecal samples from a plurality of donors and storing and indexing each respective...
2018/0243350 THERAPEUTIC AND PROPHYLACTIC COMPOSITION PRODUCED BY MICROBIOTA
The invention regards a biochemical composition obtained after separating microbes and solid, fibrous matter from a microbial ecosystem (=microbiota) by...
2018/0243349 MICROBIOTA RESTORATION THERAPY (MRT) COMPOSITIONS AND METHODS OF MANUFACTURE
Microbiota restoration therapy (MRT) compositions (e.g., oral MRT compositions) and methods for manufacturing MRT compositions are disclosed. An example method...
2018/0243348 HUMAN-DERIVED BACTERIA THAT INDUCE PROLIFERATION OR ACCUMULATION OF REGULATORY T CELLS
Species of human-derived bacteria belonging to the Clostridia class have been shown to induce accumulation of regulatory T cells (Treg cells) in the colon and...
2018/0243347 IMMUNOMODULATORY COMPOSITIONS AND METHODS OF USE THEREOF
The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present...
2018/0243346 Discovery of Root Cause of Autoimmune Disease; Rheumatoid Arthritis and Osteoarthritis
The root causes of autoimmune diseases are deformed human good bacteria that are done by chemical, environmental, X-Rays, microwave, UAV agents.
2018/0243345 METHOD FOR INCREASING MUSCLE GROWTH USING KRILL EXTRACT
The present invention relates to methods for conferring mTOR mediated physiological benefits by administering a composition having phospholipids, omega-3 fatty...
2018/0243344 OXYGENATED DEMINERALIZED BONE MATRIX FOR USE IN BONE GROWTH
An improved composition for inducing bone growth is provided that is a combination of at least DBM and an oxygen carrier. Injection/implantation of a...
2018/0243343 METHODS AND COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PARKINSON'S DISEASE
Provided are methods and compositions for the treatment and/or prevention of Parkinson's disease in humans. Specifically, the compositions comprising: (a) a...
2018/0243342 METHODS FOR PRODUCING AND USING REJUVENATED RED BLOOD CELLS
Methods for treating blood. The methods comprise obtaining whole blood from a donor, mixing the whole blood with a red blood cell enhancement composition, and...
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