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Patent # Description
2018/0243290 MORPHINAN COMPOUNDS FOR TREATING AGITATION
This invention relates to methods of treating agitation comprising administering a morphinan compound or a pharmaceutically acceptable salt thereof. This...
2018/0243289 DEUTERATED MORPHINAN COMPOUNDS FOR TREATING AGITATION
This invention relates to methods of treating agitation comprising administering a morphinan compound or a pharmaceutically acceptable salt thereof. This...
2018/0243288 COMPOSITIONS AND METHODS FOR WEIGHT LOSS IN AT RISK PATIENT POPULATIONS
The present disclosure relates to compositions, kits, uses, systems and methods related to naltrexone plus bupropion for treating an overweight or obese...
2018/0243287 METHODS AND THERAPEUTIC COMBINATIONS FOR TREATING TUMORS
Methods and therapeutic combinations useful for increasing cell-mediated anti-tumor responses are described. The methods include administering to a subject a...
2018/0243286 Antibacterial compositions of a beta-lactamase inhibitor with a cephalosporin
Pharmaceutical compositions comprising: (a) at least one cephalosporin antibacterial agent and (b) a compound of Formula (I) or a stereoisomer or a...
2018/0243285 3-(1-OXO-4-((4-((3-OXOMORPHOLINO)METHYL)BENZYL)OXY)ISOINDOLIN-2-YL)PIPERID- INE-2,6-DIONE AND ISOTOPOLOGUES THEREOF
Provided are 4'-arylmethoxy isoindoline compounds, e.g., 3-(1-oxo-4-((4-((3-oxomorpholino)methyl)benzyl)oxy)isoindolin-2-yl)piperi- dine-2,6-dione, or an...
2018/0243284 THERAPEUTIC AGENT OR TREATMENT METHOD FOR PHILADELPHIA CHROMOSOME-POSITIVE (PH+) ACUTE LYMPHOCYTIC LEUKEMIA...
According to the present invention, there is provided a pharmaceutical composition for treating Philadelphia chromosome positive lymphocytic leukemia,...
2018/0243283 PHARMACEUTICAL COMPOSITION CAPABLE OF THE INCORPORATION OF LENALIDOMIDE IN VARIOUS CRYSTALLINE MODIFICATIONS
The present invention relates to pharmaceutical compositions comprising the active substance Lenalidomide in one of the modifications selected from...
2018/0243282 Preparation and Use of Combination Enzyme and Gastrointestinal Modulator Delivery Systems
Pharmaceutical compositions comprising one or more digestive enzymes and one or more gastrointestinal modulators of acid are provided. The one or more...
2018/0243281 SOLID FORMS OF AN ASK1 INHIBITOR
Crystalline forms of 5-(4-cyclopropyl-1H-imidazol-1-yl)-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-y- l)pyridin-2-yl)-2-fluoro-4-methylbenzamide (Compound I) were...
2018/0243280 A PHARMACEUTICAL COMBINATION COMPRISING THE PI3K INHIBITOR ALPELISIB AND THE CDK4/6 INHIBITOR RIBOCICLIB, AND...
The present disclosure pertains to a pharmaceutical combination comprising (a) an alpha-isoform specific P13K inhibitor, (b) a cyclin dependent kinase 4/6...
2018/0243279 PHARMACEUTICAL COMBINATION COMPRISING THE PI3K INHIBITOR ALPELISIB AND THE B-RAF INHIBITOR DABRAFENIB; THE USE...
The present disclosure relates to a pharmaceutical combination comprising (a) alpha-isoform specific PI3K inhibitor and (b) a B-RAF inhibitor; combined...
2018/0243278 COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION
Provided herein are pharmaceutical compositions that are useful for the treatment of hypertension comprising an angiotensin II receptor blocker, a diuretic,...
2018/0243277 GRANULATE FORMULATION OF 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE AND METHOD OF MAKING THE SAME
The disclosure relates to granulate formulations of pirfenidone and methods of making such formulations.
2018/0243276 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THE TREATMENT OF HYPOXIA-RELATED DISEASES
A pharmaceutical composition including N,N,N',N'-tetrakis-(2-pyridylmethyl)-ethylenediamine (TPEN) or a pharmaceutically acceptable salt thereof, an alginate...
2018/0243275 COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES
Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a...
2018/0243274 ANTIBACTERIAL COMPOSITIONS
Pharmaceutical compositions comprising: (a) at least one antibacterial agent selected from cefixime, cefpodoxime, ceftibuten, cefuroxime or a pharmaceutically...
2018/0243273 Composition for Intravesical Administration for Treating Bladder Pain
The invention relates to a pharmaceutical composition comprising cis-(E)-4-(3-fluorophenyl)-2',3',4',9'-tetrahydro-N,N-dimethyl-2'-(1-oxo-- ...
2018/0243272 METHODS FOR TREATING IRRITABLE BOWEL SYNDROME (IBS)
The present invention provides new methods and kits for treating IBS; treating IBS in females; treating IBS in older subjects; and treating IBS in non-white...
2018/0243271 Method for Treating or Preventing Diabetic Nephropathy
The present invention provides a method for treating or preventing a renal injury-related disease such as diabetic nephropathy comprising administering to a...
2018/0243270 METHODS FOR TREATING CNS LESIONS
Provided herein are methods for repairing central nervous system, particularly brain, lesions in a subject comprising orally administering a carbonic anhydrase...
2018/0243269 FORAZOLINES, COMPOSITIONS THEREOF AND USES THEREOF
An isolated compound of Formula I and salts thereof are provided: ##STR00001## wherein X is Cl or Br. A compound isolated from Actinomadura and having a chemical...
2018/0243268 COMBINATION OF TAFIa INHIBITOR WITH PLASMINOGEN ACTIVATOR
The present invention provides a pharmaceutical composition for treatment or prevention of thrombosis or embolism or a sequela thereof, comprising a particular...
2018/0243267 AUTOTAXIN INHIBITOR COMPOUNDS
Described herein are compounds that are autotaxin inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such...
2018/0243266 METHODS OF TREATING SEIZURE DISORDERS
Methods of treating a seizure disorder with a maxi-K channel opener or a pharmaceutically acceptable salt thereof are provided. In embodiments, suitable maxi-K...
2018/0243265 COMPOSITIONS AND METHODS FOR TREATMENT OF RENAL DISEASE
The invention relates to methods, compositions, and kits for the treatment of proteinuria and/or hypertension (e.g., proteinuria and/or hypertension arising...
2018/0243264 INDOLINE DERIVATIVES FOR TREATMENT AND/OR PREVENTION OF FIBROSIS DISEASES
The invention relates to the use of Indoline derivatives, and their effective dose in the prevention and/or treatment of fibrosis diseases. The compound can...
2018/0243263 TREATMENT FOR PRIMARY BILIARY CHOLANGITIS
The present invention provides therapeutic compound for prevention and treatment of primary biliary cholangitis, (PBC). Specifically, the present invention...
2018/0243262 Method for the Treatment of Neuropathies and/or Neuropathic Pain
A method of treating a subject having neuropathies and/or neuropathic pain, that includes administering a pharmaceutical composition or dietary supplement...
2018/0243261 Compositions Comprising Urolithin Compounds
The invention provides compositions comprising a medium chain triglyceride and a urolithin. The invention also provides uses and methods associated with, or...
2018/0243260 METHODS OF TREATING COGNITIVE AND BEHAVIORAL IMPAIRMENT IN DOWN SYNDROME AND ALZHEIMERS DISEASE PATIENTS
Disclosed herein are methods of treating cognitive and behavioral impairment in Down syndrome and/or Alzheimer's disease patients, Alzheimer's disease,...
2018/0243259 Metered Dose Inhaler Compositions, Systems, and Methods
Compositions, systems, and methods that can be used with a pressurized metered dose inhaler are disclosed. A pharmaceutical composition for use in a...
2018/0243258 MELATONIN AGONIST TREATMENT
Melatonin Agonist, MA-1, is administered at effective doses.
2018/0243257 COMBINATION OF FUROSEMIDE AND STEROIDS AND USES THEREFOR
A composition of furosemide, or a pharmaceutically acceptable salt, solvate, or physiologically functional derivative thereof is combined with a steroid, or a...
2018/0243256 SOLID SOLUBLE FERRIC PYROPHOSPHATE FORMULATIONS, KITS, AND METHODS USING THE SAME
A solid particulate formulation comprising soluble ferric pyrophosphate and a sachet comprising the solid particulate formulation of soluble ferric...
2018/0243255 ANTI-CANCER AGENT COMPRISING AMINOACETONITRILE COMPOUND AS ACTIVE INGREDIENT
The present invention relates to an anticancer agent having a high safety and a superior anticancer activity, and anticancer agent containing, as an active...
2018/0243254 MIXTURE OF FATTY ACIDS AND PALMITOYLETHANOLAMIDE FOR USE IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC PATHOLOGIES
The present invention relates to a mixture containing up to two fatty acids selected from palmitic acid, oleic acid, stearic acid, linoleic acid,...
2018/0243253 FORMULATIONS CONTAINING OMEGA-3 FATTY ACIDS OR ESTERS THEREOF AND MAQUI BERRY EXTRACT AND THERAPEUTIC USES THEREOF
Provided herein are methods, formulations, and compositions related to omega-3 fatty acids or esters thereof and maqui berry extract. Methods, formulations,...
2018/0243252 METHODS AND COMPOSITIONS FOR IMPROVING MICROVASCULAR FUNCTION, SUPPRESSING CYCLOOXYGENASE ACTIVITY, REDUCING...
Methods of suppressing cyclooxygenase activity or reducing platelet aggregation of a mammal in need thereof by administering to a mammal in need thereof an...
2018/0243251 Composition and Method for Improving Cognitive Function
Embodiments of the invention provide a composition for improving cognitive function in a subject. The composition includes caffeine, mood enhancers, and...
2018/0243250 METHOD OF TREATING A DOPAMINE RELATED DISORDER IN A SUBJECT BY ADMINISTERING LEVODOPA, IN COMBINATION WITH A...
The invention relates to a method of treating a dopamine related disorder in a subject, the method comprises the steps of administering therapy to a subject,...
2018/0243249 METHODS OF TREATING PARKINSON'S DISEASE USING VIRAL VECTORS
Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection...
2018/0243247 DRUG COMBINATIONS FOR CEREBROVASCULAR DISEASE
The invention provides a drug combination of at least two compounds selected from the group consisting of Valproate, Ketamine, Tacrolimus, Clevidipine and Joro...
2018/0243246 Compositions and Methods for the Treatment and Prevention of Chronic Hypoxemia and Dyspnea.
The present invention has shown that not all salts of pyruvic acid enhance lung functions or enhance the synthesis of lung surfactants and that certain salts...
2018/0243245 LRH-1 MODULATORS
Disclosed herein are compositions and methods for modulating the liver receptor homolog-1.
2018/0243244 Prevention and Treatment of Neurodegenerative Diseases Through Autophagy Activity Mediated by A Synthetic...
The pharmacokinetics and key technologies of the present invention are summarized in FIG. 1. Particularly, malignant misfolded proteins such as mutant...
2018/0243243 Norepinephrine Compositions and Methods Therefor
The inventive subject matter is directed to compositions and methods for ready-to-inject norepinephrine compositions with improved stability. Most preferably,...
2018/0243242 COMPOSITIONS AND METHODS FOR TRANSDERMAL DELIVERY OF AMPHETAMINE
Compositions for the transdermal delivery of amphetamine in a flexible, finite form are described. The compositions comprise a polymer matrix that includes...
2018/0243241 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS
The invention also relates to pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of...
2018/0243240 TOPICAL DAPSONE AND DAPSONE/ADAPALENE COMPOSITIONS AND METHODS FOR USE THEREOF
Dapsone and dapsone/adapalene compositions can be useful for treating a variety of dermatological conditions. The compositions of this disclosure include...
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