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Patent # Description
2018/0245061 Modified Heterocyclase
This invention relates to an engineered leader-independent heterocyclase (also known as a cyclodehydratase) comprising a defined cyanobactin leader sequence...
2018/0245060 THERMOSTABLE CELLULASES
The present invention relates to a nucleic acid molecule which encodes a polypeptide having cellulase activity and which is thermostable, wherein said nucleic...
2018/0245059 CARBOHYDRATE DEGRADING POLYPEPTIDE AND USES THEREOF
The invention relates to a polypeptide having hemicellulase activity. The invention features the full length coding sequence of the novel gene as well as the...
2018/0245058 COMPOSITIONS FOR LINKING DNA-BINDING DOMAINS AND CLEAVAGE DOMAINS
Disclosed herein are compositions for linking DNA binding domains and cleavage domains (or cleavage half-domains) to form non-naturally occurring nucleases....
2018/0245057 SYSTEMS AND METHODS FOR SELECTION OF GRNA TARGETING STRANDS FOR CAS9 LOCALIZATION
The present invention provides systems and method of identifying optimal Cas9 guide strand targets to activate or repress a gene epigenetically.
2018/0245056 COMPOSITIONS FOR INCREASING POLYPEPTIDE STABILITY AND ACTIVITY, AND RELATED METHODS
This disclosure provides peptides, polypeptides, fusion polypeptides, compositions, and methods for enhancing or increasing the stability of a polypeptide...
2018/0245055 Enhanced hAT Family Transposon-Mediated Gene Transfer and Associated Compositions, Systems, and Methods
This disclosure provides various TcBuster transposases and transposons, systems, and methods of use.
2018/0245054 MUTATIONS THAT CONFER GENETIC STABILITY TO ADDITIONAL GENES IN INFLUENZA VIRUSES
The disclosure provides for an isolated recombinant influenza virus having at least one of: a PA gene segment encoding PA with a residue at position 443 that...
2018/0245053 VIRAL VACCINES AND METHODS OF FORMING THE SAME
Provided herein is a method for producing an inactivated virus including a) heating the virus to a temperature sufficient to disrupt the virus membrane; b)...
2018/0245052 ATTENUATED INFLUENZA VECTORS FOR THE PREVENTION AND/OR TREATMENT OF INFECTIOUS DISEASES AND FOR THE TREATMENT...
The present invention relates to the field of medicine and virology. An attenuated influenza A virus, an influenza virus vector based thereon, and a...
2018/0245051 METHODS FOR GENERATING INDUCED PLURIPOTENT STEM CELLS VIA CELL CYCLE SYNCHRONIZATION
The techniques described herein provide for improved efficiency of iPSC production from biological cells. The approach achieves improved iPSC production...
2018/0245050 THREE-DIMENSIONAL DIFFERENTIATION OF EPIBLAST SPHEROIDS TO KIDNEY ORGANOIDS MODELS STAGE-SPECIFIC EPITHELIAL...
Human pluripotent stem cells (hPSCs) have dual value as microphysiological laboratory models and regenerative therapeutics. hPSCs are epithelial cells, but the...
2018/0245049 METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS
A cell culture including a cell culturing medium for growing stem cells, a three-dimensional (3D) cell growth matrix and stem cells, wherein the cell culture...
2018/0245048 METHODS AND COMPOSITIONS FOR EXPANSION AND DIFFERENTIATION OF SKELETAL MUSCLE STEM CELLS OR PROGENITOR CELLS
The present disclosure describes compositions for preparing a myofiber or myotube from a skeletal muscle stem cell or progenitor cell comprising a carnitine...
2018/0245047 METHOD FOR REDUCING PLURIPOTENT STEM CELLS, METHOD FOR PRODUCING CELL POPULATION HAVING REDUCED PLURIPOTENT...
The present invention pertains to a method for culturing a cell population including pluripotent stem cells and differentiated cells derived from pluripotent...
2018/0245046 METHOD FOR PRODUCING MESENCHYMAL CELLS WITH PROMOTED c-MPL RECEPTOR EXPRESSION ON CELL SURFACE
An object of the present invention is to provide a method of simply and efficiently promoting expression of c-MPL on a surface of a mesenchymal cell. The...
2018/0245045 METHODS OF EXPANDING HEMATOPOIETIC STEM CELLS, COMPOSITIONS, AND METHODS OF USE THEREOF
Described herein are methods of expanding a population of hematopoietic stem cells by contacting the population of hematopoietic stem cells with an effective...
2018/0245044 METHOD FOR NATURAL KILLER CELL EXPANSION
The present invention provides a method for in-vitro culturing and expanding natural killer (NK) cells in a cell culture medium comprising a population of NK...
2018/0245043 METHOD OF BLOOD POOLING AND STORAGE
The disclosure provides methods of making a cell-containing product having a uniform amount of cells therein. The method comprises pooling red blood cells from...
2018/0245042 METHODS AND MATERIALS FOR EXPANDING ANTIGEN-SPECIFIC T CELLS IN CULTURE
This document provides methods and materials for expanding antigen-specific T cells (e.g., antigen-specific CD4+ T cells and/or antigen-specific CD8+ T cells)...
2018/0245041 PLURIPOTENT STEM CELL PRODUCTION SYSTEM
A stem cell production system provided with a preintroduction cell-feeding solution channel 20 through which a solution containing cells passes, an induction...
2018/0245040 PREPARATION METHOD FOR OLFACTORY ENSHEATHING CELLS
Provided is a preparation method for olfactory ensheathing cells. The method comprises the steps of formulation of a cell medium, collection and pretreatment...
2018/0245039 METHOD FOR PRODUCING RETINAL TISSUE
The present invention provides a production method of a retinal cell or retinal tissue, including the following steps: (1) a first step of culturing mammalian...
2018/0245038 METHOD FOR GENERATING SOMATIC STEM CELLS
The present invention provides a method for generating somatic stem cells out of differentiated cells, somatic stem cells obtained by this method and a vector...
2018/0245037 Non-Invasive Methods for Assessing Genetic Integrity of Pluripotent Stem Cells
The present invention relates to a novel non-invasive method for assessing pluripotent stem cells quality in culture. More specifically, the present invention...
2018/0245036 OOCYTES DERIVED FROM OVARIAN CULTURE INITIALLY CONTAINING NO OOCYTES
Ovarian germ-line-competent embryonic stem cells (GLC-ESC) are cultured, either in the presence or absence of a compound having estrogenic activity. The...
2018/0245035 CULTURE MEDIUM AND METHOD FOR PRODUCING CULTURE MEDIUM
Provided is a culture medium including fibers aligned in one direction, and a method for producing the same. The culture medium includes: a substrate; a frame...
2018/0245034 Biomass with bioengineered microorganism such as yeast, associated organic compounds, and related methods
Provided are various genetically engineered strains, TEKK microorganisms, e.g., yeast, in a container of industrial-scale volume, e.g., a reaction tank,...
2018/0245033 A METHOD OF CULTURING HAEMATOCOCCUS SPECIES FOR MANUFACTURING OF ASTAXANTHIN
A method of culturing Haematococcus species for manufacturing of astaxanthin comprising the steps of: providing a substrate, arranging the Haematococcus...
2018/0245032 CELL SUPPORT COMPOSITE AND METHOD FOR PRODUCING CELL SUPPORT COMPOSITE
A cell support composite includes: a substrate formed of an artificial material; a laminin molecule or a fragment thereof which adheres to at least a part of...
2018/0245031 TEMPERATURE ADJUSTMENT APPARATUS
Provided is a highly reliable temperature adjustment apparatus which uses a temperature adjustment element and quantitatively evaluates the temperature...
2018/0245030 AGING OF ALCOHOLIC BEVERAGES USING CONTROLLED MECHANICALLY INDUCED CAVITATION
An extreme acceleration of the process of aging spirits to obtain aged liquors includes circulating the spirits through a cavitation zone within a controlled...
2018/0245029 AUTOMATED BEER-BREWING SYSTEM AND METHOD WITH BREW CYCLE CONTROL VALVE ARRANGEMENT
A automated beer-brewing system and method includes plural brewing containers, supply containers, and post-beer-brewing containers to bottle the brewed beer...
2018/0245028 WATER-SOLUBLE FILM, CHEMICAL AGENT PACKAGE AND WATER-SOLUBLE FILM PRODUCTION METHOD
A water-soluble film contains a polyvinyl alcohol resin (A), and has a complete dissolution time (T) and a curl area percentage (S), wherein a product...
2018/0245027 CLEANING COMPOSITION HAVING HIGH SELF-ADHESION AND PROVIDING RESIDUAL BENEFITS
A composition for treating a hard surface. The composition has: (a) at least one adhesion promoter; (b) at least one surfactant selected from the group...
2018/0245026 SYSTEM FOR DISPENSING A SOLUTION OF NITRIC OXIDE IN DEIONIZED AND/OR DEOXYGENATED WATER FROM A VESSEL
A pressurized containment vessel for a gas/liquid mixture of nitric oxide in deionized and/or deoxygenated water and a system for dispensing the gas/liquid...
2018/0245025 Leuco Triphenylmethane Colorants As Bluing Agents In Laundry Care Compositions
This application describes laundry care compositions that contain leuco colorants and their use in the laundering of textile articles. These types of colorants...
2018/0245024 DETERGENT COMPOSITIONS WITH LIPASE AND BIOSURFACTANT
Compositions comprising lipases and biosurfactants, especially psychrophilic lipases and biosurfactants.
2018/0245023 LIQUID DETERGENCY COMPOSITION COMPRISING PROTEASE AND NON-PROTEASE ENZYME
A liquid detergency composition comprising: protease and non-protease enzyme wherein at least part of either the protease or the non-protease enzyme is...
2018/0245022 ALKALINE CLEANING COMPOSITION COMPRISING AN ALKYLAMINO HYDROXY ACID AND/OR SECONDARY AMINE AND METHODS OF...
The invention relates to compositions, methods of manufacture, and methods for reducing metal corrosion during alkaline cleaning. In particular, the method...
2018/0245021 ALKALINE CLEANING COMPOSITION COMPRISING A HYDROXYPHOSPHONO CARBOXYLIC ACID AND METHODS OF REDUCING METAL CORROSION
The invention relates to compositions, methods of manufacture, and methods for reducing metal corrosion during alkaline cleaning. In particular, the method...
2018/0245020 METHOD OF FORMING AN ANTIFOAM GRANULE
An antifoam granule includes a carrier and an antifoam compound deposited on the carrier. The antifoam granule is formed using a method that includes providing...
2018/0245019 EFFICIENT SURFACTANT SYSTEM ON PLASTIC AND ALL TYPES OF WARE
Surfactant systems and compositions incorporating the same are disclosed for use as rinse aids on plastics and other wares. The surfactant systems and...
2018/0245018 A SYNERGISTIC PERFUMING COMPOSITION
The present invention relates to the field of perfumery and more precisely it concerns a perfuming composition, and the consumer articles associated therewith,...
2018/0245017 LUBRICANT FORMULATIONS WITH ENHANCED ANTI-WEAR AND EXTREME PRESSURE PERFORMANCE
A lubricant formulation contains: (a) greater than 50 weight-percent hydrocarbon base oil; (b) 5 weight-percent or more and less than 50 weight-percent of one...
2018/0245016 FLUID WITH POLYALKYLENE GLYCOL AND UNSATURATED ESTER
A fluid contains a base oil consisting of an alcohol-initiated polyalkylene glycol where polyalkylene glycol component is selected from a homopolymer of...
2018/0245015 LUBRICATION OIL COMPOSITION WITH ENHANCED WEAR AND LOW SPEED PRE-IGNITION PROPERTIES
A lubricating oil composition having a sulfated ash content of from greater than 1.0 wt. % to about 2.0 wt. %, a phosphorus content of from about 0.07 to about...
2018/0245014 VISCOSITY INDEX IMPROVER, LUBRICANT COMPOSITION, AND METHOD FOR MANUFACTURING LUBRICANT COMPOSITION
The present invention provides a viscosity index improver having an excellent viscosity index improving effect, a lubricant composition having excellent...
2018/0245013 HYDROGENATED POLYBUTADIENES USEFUL AS LUBRICANT ADDITIVES
The invention relates to low molecular weight hydrogenated polybutadienes and to a method for the preparation of these polymers. The invention is also directed...
2018/0245012 Azole Derivatives as Lubricating Additives
Lubricating compositions comprising an azole-acrylic adduct formed by contacting an azole compound with an acrylic. The adduct formed has at least one...
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