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Patent # | Description |
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2018/0250431 |
METHOD AND DEVICE FOR ENHANCING THE REDUCTION OF PATHOGENS, ALLERGENS AND
ODOR-CAUSING AGENTS Disclosed are methods and apparatus that help reduce and prevent infection by controlling and/or reducing the level of contaminants, which include pathogens,... |
2018/0250430 |
AIR MONITORING AND FILTRATION DEVICE FOR DETECTING AND REMOVING ODORS An odor detection and filtration device is provided including a housing enclosing a void and having and air inlet and air outlet. The void contains, and the... |
2018/0250429 |
DEVICE AND METHOD FOR STERILIZATION OF INSTRUMENTS AND SURFACES A device for decontaminating a medical device, the device including a compartment adapted to contain a medical device and a solution, the solution comprising a... |
2018/0250428 |
ULTRASOUND SYSTEM WITH DISINFECTING FEATURE An ultrasound imaging system (100) including a disinfection system is disclosed. The disinfection system may include one or more ultraviolet light sources... |
2018/0250427 |
SYSTEM AND METHOD FOR ELECTRICAL CONTROL OF BACTERIA A system and method for controlling microbial growth on and in medical devices and implants, especially biofilm infections, involves using pulsed electric... |
2018/0250426 |
CONTRAST AGENTS, METHODS FOR PREPARING CONTRAST AGENTS, AND METHODS OF
IMAGING Embodiments of the present disclosure provide for contrast agents, methods of making contrast agents, and methods of using contrast agents, and the like. |
2018/0250425 |
TRIFUNCTIONAL AND COMPLETELY CLEARABLE SPECIFIC TARGETING AGENTS AND
METHODS THEREOF The invention provides a novel trifunctional targeting construct and related compositions and methods that are useful in therapeutic, diagnostic (including... |
2018/0250424 |
COMPOSITIONS AND METHODS FOR PROMOTING HOMOLOGY DIRECTED REPAIR This application provides improved methods of genome editing. Cas9 molecules can be used to create a break in a genomic region of interest. To increase the... |
2018/0250423 |
METHODS AND MATERIALS FOR GALGT2 GENE THERAPY The present disclosure relates to recombinant adeno-associated virus (rAAV) delivery of a GALGT2 polynucleotide. The disclosure provides rAAV and methods of... |
2018/0250422 |
METHODS OF TREATING NEURODEGENERATIVE DISORDERS The present disclosure is directed to adeno -associated viral vector monoclonal antibody constructs and compositions thereof, methods of improving locomotor... |
2018/0250421 |
COMPOSITION FOR TREATING PAIN The present invention relates to: a composition for alleviating or treating pain, the composition comprising glutamate decarboxylase and a gene coding for an... |
2018/0250420 |
MULTIPLE HUMAN ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS OF FORMATION A nanoconjugate that includes multiple antibody agents bonded to a single nanoparticles via a linker to form a conjugate having either electrostatic or... |
2018/0250419 |
COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR RELATED DISORDERS The present invention relates to nanoparticles complexed with therapeutic agents configured for treating cardiovascular related disorders, and methods of... |
2018/0250418 |
ANTI-cMet ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE The present disclosure provides antibody drug conjugates that bind human cMET, their methods of making, and their uses to treat patients having cancer. |
2018/0250417 |
PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES Conjugates of an antibody that binds to CD19 with PBD dimers. |
2018/0250416 |
COMPOSITIONS, METHODS AND USES FOR ALPHA-1 ANTITRYPSIN FUSION MOLECULES Embodiments herein report compositions of and methods for making and using alpha-1 antitrypsin (AAT) fusion molecules or peptide derivatives thereof. In... |
2018/0250415 |
DUAL VARIABLE DOMAIN IMMUNOCONJUGATES AND USES THEREOF Dual variable domain (DVD) immunoconjugates and uses thereof are provided. Aspects of the subject immunoconjugates include a DVD immunoglobulin molecule having... |
2018/0250414 |
PEPTIDE-BASED MULTIPLE-DRUG DELIVERY VEHICLE A molecular structure comprising a targeting moiety, a multi-functional peptide platform and a plurality of controllably released bioactive agents attached... |
2018/0250413 |
TARGETED DELIVERY OF DRUGS, THERAPEUTIC NUCLEIC ACIDS AND FUNCTIONAL
NUCLEIC ACIDS TO MAMMALIAN CELLS VIA... A composition comprising intact killed bacterial cells that contain a therapeutic nucleic acid, a drug or a functional nucleic acid is useful for targeted... |
2018/0250412 |
FUNCTIONAL HYDRATED HYALURONIC ACID AND METHOD FOR PRODUCING COATED LACTIC
ACID BACTERIA HAVING EXCELLENT... The present invention relates to a functional hydrated hyaluronic acid and a method for producing 5.sup.th generation coated lactic acid bacteria having... |
2018/0250411 |
DERMATOLOGICAL COMPOSITIONS AND METHODS USING SAME The present invention provides topical compositions that are useful in treating and/or preventing at least one disease selected from the group consisting of... |
2018/0250410 |
MODIFIED POLY (BETA-AMINO ESTER)S FOR DRUG DELIVERY Disclosed are polymers that are poly(beta-amino ester)s (PBAEs) modified with at least one oligopeptide. The polymers may be used in any field where polymers... |
2018/0250409 |
PHARMACEUTICAL COMPOSITION CONTAINING ANIONIC DRUG, AND PREPARATION METHOD
THEREFOR Disclosed are a pharmaceutical composition for anionic drug delivery, and a preparation method therefor, the pharmaceutical composition for anionic drug... |
2018/0250408 |
OPHTHALMIC COMPOSITION The present invention relates to ophthalmic compositions for treatment of conditions in the eye. More specifically, the present invention relates to ophthalmic... |
2018/0250407 |
PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These... |
2018/0250406 |
RS7 Antibodies This invention relates to monovalent and multivalent, monospecific binding proteins and to multivalent, multispecific binding proteins. One embodiment of these... |
2018/0250405 |
COMPOSITIONS, COMBINATIONS AND RELATED METHODS FOR PHOTOIMMUNOTHERAPY Provided herein are conjugates, compositions and methods for use in photoimmunotherapy, such as photoimmunotherapy induced by activation of a phthalocyanine... |
2018/0250404 |
HIGH-Z NANOPARTICLES AND THE USE THEREOF IN RADIATION THERAPY Methods for sensitizing target cells to ionizing radiation are provided comprising the administration of high-Z particles (e.g., gold nanoparticles) in... |
2018/0250403 |
CONJUGATES The present invention relates to improved compositions for photodynamic therapy (PDT) for the selective destruction of malignant, diseased, or infected cells... |
2018/0250402 |
LIGHT-RESPONSIVE POLYPEPTIDES AND METHODS OF USE THEREOF The present disclosure provides variant light-responsive polypeptides, and nucleic acids comprising nucleotide sequences encoding the light-responsive... |
2018/0250401 |
STABILIZATION OF IMMUNOGLOBULINS THROUGH AQUEOUS FORMULATION WITH
HISTIDINE AT WEAK ACIDIC TO NEUTRAL PH The present invention provides, among other aspects, storage stable aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH.... |
2018/0250400 |
Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2
Inhibitor, and/or a CDK4/6 Inhibitor Therapeutic combinations of a phosphoinositide 3-kinase (PI3K) inhibitor, including PI3K inhibitors selective for the .gamma.- and .delta.-isoforms and... |
2018/0250399 |
VACCINE The disclosure relates to polypeptides and pharmaceutical compositions comprising polypeptides that find use in the prevention or treatment of cancer, in... |
2018/0250398 |
CO-THERAPY COMPRISING A SMALL MOLECULE CSF-1R INHIBITOR AND AN AGONISTIC
ANTIBODY THAT SPECIFICALLY BINDS CD40... The present invention is directed to methods for treating cancer, preferably a solid tumor or hematological malignancy, including for example pancreatic... |
2018/0250397 |
ADJUVANT TREATMENT OF HER2-POSITIVE BREAST CANCER Methods are provided for the adjuvant treatment of operable HER2-positive primary breast cancer in human patients by administration of pertuzumab in addition... |
2018/0250396 |
BISPECIFIC ANTIBODIES FOR USE IN CANCER IMMUNOTHERAPY The present invention concerns the field of cancer immunotherapy, and in particular drugs with low toxicity which can overcome drug-resistance. The present... |
2018/0250395 |
CD47 ANTIBODIES, METHODS, AND USES The present disclosure relates generally to monoclonal antibodies that specifically bind to CD47, more specifically to CD47 antibodies that do not have... |
2018/0250394 |
MIT BIOMARKERS AND METHODS USING THE SAME Provided are therapies related to the treatment of pathological conditions, such as cancer. |
2018/0250393 |
MANIPULATION OF T CELL AND MAST CELL ACTIVATION BY PIK3IP1 The present disclosure relates to compounds and compositions useful as PIK3IP1 agonists and methods of treating inflammatory diseases or allergic conditions or... |
2018/0250391 |
COMPOSITIONS AND METHODS FOR INDUCING AND ENHANCING AN IMMUNE RESPONSE The present invention relates to compositions and methods for modulating immune responses using at least one cycli di-nucleotide synthetase enzyme gene. Such... |
2018/0250390 |
PROCESS FOR PREPARING PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATES An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate... |
2018/0250389 |
VACCINE COMPRISING STREPTOCOCCUS PNEUMONIAE CAPSULAR POLYSACCHARIDE
CONJUGATES The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is... |
2018/0250388 |
TREATMENT OF INSECT BITE HYPERSENSITIVITY The present invention relates to compositions, immunogenic or vaccine compositions and pharmaceutical compositions for the prevention or treatment of insect... |
2018/0250387 |
COMPOSITIONS AGAINST CAT ALLERGY The present invention relates to the use of a composition in a method of reducing the allergenicity of a cat. Moreover, the present invention relates to the... |
2018/0250386 |
COMBINATION THERAPIES FOR HUMAN PAPILLOMAVIRUS-ASSOCIATED DISEASES
COMPRISING ADMINISTRATION OF THERAPEUTIC... The present disclosure relates to a combination therapy comprising a therapeutic vaccine and a recombinant vaccinia virus for treating HPV-associated diseases.... |
2018/0250385 |
METHODS FOR INDUCING PROTECTIVE IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY
VIRUS INFECTION Compositions, vaccines and methods for inducing protective immunity against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine... |
2018/0250384 |
IMMUNOGENIC ANTIGEN IDENTIFICATION FROM A PATHOGEN AND CORRELATION TO
CLINICAL EFFICACY Embodiments of the disclosure concern methods of identifying whether or not antigens from a particular pathogen are immunogenic, including the order of their... |
2018/0250383 |
Methods of Treating and Preventing Influenza Infections The invention relates to composite antigens comprising a peptide with contiguous amino acid sequence derived from a plurality of antigenic epitopes of one or... |
2018/0250382 |
Inactivated Canine Influenza Vaccines and Methods of Making and Uses
Thereof The present invention relates to canine influenza virus strains, and vaccines and compositions. The present invention also relates to reagents and methods... |
2018/0250381 |
SOLUBLE NEEDLE ARRAYS FOR DELIVERY OF INFLUENZA VACCINES Influenza vaccines are administered using solid biodegradable microneedles. The microneedles are fabricated from the influenza vaccine in combination with... |