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Patent # Description
2018/0250431 METHOD AND DEVICE FOR ENHANCING THE REDUCTION OF PATHOGENS, ALLERGENS AND ODOR-CAUSING AGENTS
Disclosed are methods and apparatus that help reduce and prevent infection by controlling and/or reducing the level of contaminants, which include pathogens,...
2018/0250430 AIR MONITORING AND FILTRATION DEVICE FOR DETECTING AND REMOVING ODORS
An odor detection and filtration device is provided including a housing enclosing a void and having and air inlet and air outlet. The void contains, and the...
2018/0250429 DEVICE AND METHOD FOR STERILIZATION OF INSTRUMENTS AND SURFACES
A device for decontaminating a medical device, the device including a compartment adapted to contain a medical device and a solution, the solution comprising a...
2018/0250428 ULTRASOUND SYSTEM WITH DISINFECTING FEATURE
An ultrasound imaging system (100) including a disinfection system is disclosed. The disinfection system may include one or more ultraviolet light sources...
2018/0250427 SYSTEM AND METHOD FOR ELECTRICAL CONTROL OF BACTERIA
A system and method for controlling microbial growth on and in medical devices and implants, especially biofilm infections, involves using pulsed electric...
2018/0250426 CONTRAST AGENTS, METHODS FOR PREPARING CONTRAST AGENTS, AND METHODS OF IMAGING
Embodiments of the present disclosure provide for contrast agents, methods of making contrast agents, and methods of using contrast agents, and the like.
2018/0250425 TRIFUNCTIONAL AND COMPLETELY CLEARABLE SPECIFIC TARGETING AGENTS AND METHODS THEREOF
The invention provides a novel trifunctional targeting construct and related compositions and methods that are useful in therapeutic, diagnostic (including...
2018/0250424 COMPOSITIONS AND METHODS FOR PROMOTING HOMOLOGY DIRECTED REPAIR
This application provides improved methods of genome editing. Cas9 molecules can be used to create a break in a genomic region of interest. To increase the...
2018/0250423 METHODS AND MATERIALS FOR GALGT2 GENE THERAPY
The present disclosure relates to recombinant adeno-associated virus (rAAV) delivery of a GALGT2 polynucleotide. The disclosure provides rAAV and methods of...
2018/0250422 METHODS OF TREATING NEURODEGENERATIVE DISORDERS
The present disclosure is directed to adeno -associated viral vector monoclonal antibody constructs and compositions thereof, methods of improving locomotor...
2018/0250421 COMPOSITION FOR TREATING PAIN
The present invention relates to: a composition for alleviating or treating pain, the composition comprising glutamate decarboxylase and a gene coding for an...
2018/0250420 MULTIPLE HUMAN ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS OF FORMATION
A nanoconjugate that includes multiple antibody agents bonded to a single nanoparticles via a linker to form a conjugate having either electrostatic or...
2018/0250419 COMPOSITIONS AND METHODS FOR TREATING CARDIOVASCULAR RELATED DISORDERS
The present invention relates to nanoparticles complexed with therapeutic agents configured for treating cardiovascular related disorders, and methods of...
2018/0250418 ANTI-cMet ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE
The present disclosure provides antibody drug conjugates that bind human cMET, their methods of making, and their uses to treat patients having cancer.
2018/0250417 PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES
Conjugates of an antibody that binds to CD19 with PBD dimers.
2018/0250416 COMPOSITIONS, METHODS AND USES FOR ALPHA-1 ANTITRYPSIN FUSION MOLECULES
Embodiments herein report compositions of and methods for making and using alpha-1 antitrypsin (AAT) fusion molecules or peptide derivatives thereof. In...
2018/0250415 DUAL VARIABLE DOMAIN IMMUNOCONJUGATES AND USES THEREOF
Dual variable domain (DVD) immunoconjugates and uses thereof are provided. Aspects of the subject immunoconjugates include a DVD immunoglobulin molecule having...
2018/0250414 PEPTIDE-BASED MULTIPLE-DRUG DELIVERY VEHICLE
A molecular structure comprising a targeting moiety, a multi-functional peptide platform and a plurality of controllably released bioactive agents attached...
2018/0250413 TARGETED DELIVERY OF DRUGS, THERAPEUTIC NUCLEIC ACIDS AND FUNCTIONAL NUCLEIC ACIDS TO MAMMALIAN CELLS VIA...
A composition comprising intact killed bacterial cells that contain a therapeutic nucleic acid, a drug or a functional nucleic acid is useful for targeted...
2018/0250412 FUNCTIONAL HYDRATED HYALURONIC ACID AND METHOD FOR PRODUCING COATED LACTIC ACID BACTERIA HAVING EXCELLENT...
The present invention relates to a functional hydrated hyaluronic acid and a method for producing 5.sup.th generation coated lactic acid bacteria having...
2018/0250411 DERMATOLOGICAL COMPOSITIONS AND METHODS USING SAME
The present invention provides topical compositions that are useful in treating and/or preventing at least one disease selected from the group consisting of...
2018/0250410 MODIFIED POLY (BETA-AMINO ESTER)S FOR DRUG DELIVERY
Disclosed are polymers that are poly(beta-amino ester)s (PBAEs) modified with at least one oligopeptide. The polymers may be used in any field where polymers...
2018/0250409 PHARMACEUTICAL COMPOSITION CONTAINING ANIONIC DRUG, AND PREPARATION METHOD THEREFOR
Disclosed are a pharmaceutical composition for anionic drug delivery, and a preparation method therefor, the pharmaceutical composition for anionic drug...
2018/0250408 OPHTHALMIC COMPOSITION
The present invention relates to ophthalmic compositions for treatment of conditions in the eye. More specifically, the present invention relates to ophthalmic...
2018/0250407 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM
Disclosed herein are compositions comprising an NSAID such as meloxicam in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These...
2018/0250406 RS7 Antibodies
This invention relates to monovalent and multivalent, monospecific binding proteins and to multivalent, multispecific binding proteins. One embodiment of these...
2018/0250405 COMPOSITIONS, COMBINATIONS AND RELATED METHODS FOR PHOTOIMMUNOTHERAPY
Provided herein are conjugates, compositions and methods for use in photoimmunotherapy, such as photoimmunotherapy induced by activation of a phthalocyanine...
2018/0250404 HIGH-Z NANOPARTICLES AND THE USE THEREOF IN RADIATION THERAPY
Methods for sensitizing target cells to ionizing radiation are provided comprising the administration of high-Z particles (e.g., gold nanoparticles) in...
2018/0250403 CONJUGATES
The present invention relates to improved compositions for photodynamic therapy (PDT) for the selective destruction of malignant, diseased, or infected cells...
2018/0250402 LIGHT-RESPONSIVE POLYPEPTIDES AND METHODS OF USE THEREOF
The present disclosure provides variant light-responsive polypeptides, and nucleic acids comprising nucleotide sequences encoding the light-responsive...
2018/0250401 STABILIZATION OF IMMUNOGLOBULINS THROUGH AQUEOUS FORMULATION WITH HISTIDINE AT WEAK ACIDIC TO NEUTRAL PH
The present invention provides, among other aspects, storage stable aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH....
2018/0250400 Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a CDK4/6 Inhibitor
Therapeutic combinations of a phosphoinositide 3-kinase (PI3K) inhibitor, including PI3K inhibitors selective for the .gamma.- and .delta.-isoforms and...
2018/0250399 VACCINE
The disclosure relates to polypeptides and pharmaceutical compositions comprising polypeptides that find use in the prevention or treatment of cancer, in...
2018/0250398 CO-THERAPY COMPRISING A SMALL MOLECULE CSF-1R INHIBITOR AND AN AGONISTIC ANTIBODY THAT SPECIFICALLY BINDS CD40...
The present invention is directed to methods for treating cancer, preferably a solid tumor or hematological malignancy, including for example pancreatic...
2018/0250397 ADJUVANT TREATMENT OF HER2-POSITIVE BREAST CANCER
Methods are provided for the adjuvant treatment of operable HER2-positive primary breast cancer in human patients by administration of pertuzumab in addition...
2018/0250396 BISPECIFIC ANTIBODIES FOR USE IN CANCER IMMUNOTHERAPY
The present invention concerns the field of cancer immunotherapy, and in particular drugs with low toxicity which can overcome drug-resistance. The present...
2018/0250395 CD47 ANTIBODIES, METHODS, AND USES
The present disclosure relates generally to monoclonal antibodies that specifically bind to CD47, more specifically to CD47 antibodies that do not have...
2018/0250394 MIT BIOMARKERS AND METHODS USING THE SAME
Provided are therapies related to the treatment of pathological conditions, such as cancer.
2018/0250393 MANIPULATION OF T CELL AND MAST CELL ACTIVATION BY PIK3IP1
The present disclosure relates to compounds and compositions useful as PIK3IP1 agonists and methods of treating inflammatory diseases or allergic conditions or...
2018/0250391 COMPOSITIONS AND METHODS FOR INDUCING AND ENHANCING AN IMMUNE RESPONSE
The present invention relates to compositions and methods for modulating immune responses using at least one cycli di-nucleotide synthetase enzyme gene. Such...
2018/0250390 PROCESS FOR PREPARING PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATES
An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate...
2018/0250389 VACCINE COMPRISING STREPTOCOCCUS PNEUMONIAE CAPSULAR POLYSACCHARIDE CONJUGATES
The present invention discloses an immunogenic composition comprising S. pneumoniae capsular saccharide conjugates from serotypes 19A and 19F wherein 19A is...
2018/0250388 TREATMENT OF INSECT BITE HYPERSENSITIVITY
The present invention relates to compositions, immunogenic or vaccine compositions and pharmaceutical compositions for the prevention or treatment of insect...
2018/0250387 COMPOSITIONS AGAINST CAT ALLERGY
The present invention relates to the use of a composition in a method of reducing the allergenicity of a cat. Moreover, the present invention relates to the...
2018/0250386 COMBINATION THERAPIES FOR HUMAN PAPILLOMAVIRUS-ASSOCIATED DISEASES COMPRISING ADMINISTRATION OF THERAPEUTIC...
The present disclosure relates to a combination therapy comprising a therapeutic vaccine and a recombinant vaccinia virus for treating HPV-associated diseases....
2018/0250385 METHODS FOR INDUCING PROTECTIVE IMMUNITY AGAINST HUMAN IMMUNODEFICIENCY VIRUS INFECTION
Compositions, vaccines and methods for inducing protective immunity against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine...
2018/0250384 IMMUNOGENIC ANTIGEN IDENTIFICATION FROM A PATHOGEN AND CORRELATION TO CLINICAL EFFICACY
Embodiments of the disclosure concern methods of identifying whether or not antigens from a particular pathogen are immunogenic, including the order of their...
2018/0250383 Methods of Treating and Preventing Influenza Infections
The invention relates to composite antigens comprising a peptide with contiguous amino acid sequence derived from a plurality of antigenic epitopes of one or...
2018/0250382 Inactivated Canine Influenza Vaccines and Methods of Making and Uses Thereof
The present invention relates to canine influenza virus strains, and vaccines and compositions. The present invention also relates to reagents and methods...
2018/0250381 SOLUBLE NEEDLE ARRAYS FOR DELIVERY OF INFLUENZA VACCINES
Influenza vaccines are administered using solid biodegradable microneedles. The microneedles are fabricated from the influenza vaccine in combination with...
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