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| Patent # | Description |
|---|---|
| 2018/0250380 |
TREATMENT OF PIGS WITH PCV2 ANTIGEN The present invention relates to a method for the treatment or prophylaxis of a PCV2 infection or for reduction of clinical symptoms caused by or associated... |
| 2018/0250379 |
GENERATION OF HPV-SPECIFIC T-CELLS Embodiments of the disclosure concern methods and compositions for immunotherapy for human papillomavirus infection and diseases associated therewith. In... |
| 2018/0250378 |
COMBINATION OF THERAPEUTIC VACCINE AND PD-1-RELATED BLOCKADE FOR TREATING
HUMAN PAPILLOMAVIRUS-ASSOCIATED DISEASES The present disclosure relates to an immunostimulatory combination comprising a therapeutic vaccine and a PD-1-related blockade for treating human... |
| 2018/0250377 |
BACILLUS BASED DELIVERY SYSTEM AND METHODS OF USE Herein a Bacillus exosporium antigen delivery (BEAD) system that provides a means to introduce recombinant proteins or small molecules into the exosporium of... |
| 2018/0250376 |
MODIFIED ANTHRAX TOXIN PROTECTIVE ANTIGEN Disclosed is a Bacillus anthracis protective antigen (PA) comprising a PA amino acid sequence, wherein one or more of amino acid residues I207, I210, E654,... |
| 2018/0250375 |
NOVEL METHODS FOR INDUCING AN IMMUNE RESPONSE The present invention relates to methods for inducing an immune response, in particular methods for inducing an immune response against mycobacterial... |
| 2018/0250374 |
NOVEL PEPTIDES, COMBINATION OF PEPTIDES AND SCAFFOLDS FOR USE IN
IMMUNOTHERAPEUTIC TREATMENT OF VARIOUS CANCERS The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates... |
| 2018/0250373 |
NOVEL PEPTIDES, COMBINATION OF PEPTIDES AND SCAFFOLDS FOR USE IN
IMMUNOTHERAPEUTIC TREATMENT OF VARIOUS CANCERS The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates... |
| 2018/0250372 |
COMPOSITIONS FOR TREATING AN ARTHRITIC CONDITION Methods for treating an arthritic condition in a subject by administering to the subject at least one human Tr1 cell population directed to a joint-associated... |
| 2018/0250371 |
CRYSTALLIZED OXALATE DECARBOXYLASE AND METHODS OF USE Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a... |
| 2018/0250370 |
TREATMENT OF RETINITIS PIGMENTOSA USING ENGINEERED MEGANUCLEASES Disclosed are recombinant meganucleases engineered to recognize and cleave recognition sequences present in a mutant RHO P23H allele. The invention further... |
| 2018/0250369 |
LACTOFERRIN COMPOSITIONS AND METHODS FOR MODULATION OF T CELL SUBTYPES AND
TREATMENT OF AUTOIMMUNE DISEASES Provided herein are improved compositions comprising lactoferrin and methods for modulating T cell subtypes and their activities in a subject, to improve the... |
| 2018/0250368 |
LIQUID COMPOSITION OF HUMAN ALBUMIN FOR THERAPEUTIC USE Disclosed is a liquid composition of human albumin for therapeutic use, in which at least 50% of the albumin has a molecular weight of 66.438 Da, plus or minus... |
| 2018/0250367 |
POLYMER-FACTOR VIII MOIETY CONJUGATES Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a... |
| 2018/0250366 |
COMPOSITIONS AND METHODS FOR PROTECTING THE KIDNEY FROM ISCHEMIA
REPERFUSION INJURY The effects of hepcidin treatment on mitigating IRI and acute kidney injury by decreasing iron availability and ROS-mediated cell death were tested. C57Bl/6... |
| 2018/0250365 |
ACTH FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS Provided herein are methods of treatment of Amyotrophic Lateral Sclerosis comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog,... |
| 2018/0250364 |
Methods of Using Interleukin-10 for Treating Diseases and Disorders Methods of treating subjects having a disease or disorder responsive to IL-10, including methods of administration and dosing regimens associated therewith,... |
| 2018/0250363 |
Pegylated Interleukin-10 Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for... |
| 2018/0250362 |
Methods of Treating Fungal Infections The invention relates to methods of treating a fungal infection in a subject in need thereof comprising administering to the subject a therapeutically... |
| 2018/0250361 |
Methods, Compounds and Compositions for Modulating Blood Brain Barrier
Integrity and Re-myelination Disclosed herein are methods and compositions for increasing and decreasing the permeability of the blood brain barrier for the treatment of diseases and... |
| 2018/0250360 |
METHOD FOR DETECTING CANCER CELLS, REAGENT FOR INTRODUCING SUBSTANCE INTO
CANCER CELLS, AND COMPOSITION FOR... As a technique for specifically detecting cancer cells, provided is a method for detecting cancer cells, including the steps of: bringing BC2LCN lectin into... |
| 2018/0250359 |
COMBINATION THERAPY USING GLIADIN AND GAMMA AMINOBUTYRIC ACID The present invention relates to the use of gliadin in medicine, in combination with gamma aminobutyric acid, and/or an antigen such as a beta cell autoantigen. |
| 2018/0250358 |
GHRH AGONISTS FOR THE TREATMENT OF ISCHEMIC DISORDERS Disclosed herein are compositions of GHRH agonists and peptides, and methods to treat disorders, such as ischemia and reperfusion injury. In one embodiment, a... |
| 2018/0250357 |
METHODS COMPRISING DESMOPRESSIN The present disclosure is directed to gender, age, and dose effects of desmopressin on reducing nocturnal voids, increasing an initial period of undisturbed... |
| 2018/0250356 |
TARGETING G3BP PROTEINS TO ACCELERATE NERVE REGENERATION Methods for using a peptide to effectively increase axon growth in both naive and injury-conditioned neurons. |
| 2018/0250355 |
COMPOSITIONS AND METHODS FOR IMPROVING SEXUAL FUNCTION The embodiments include methods of improving sexual function in a male with benign prostatic hyperplasia (BPH), using compositions containing compounds based... |
| 2018/0250354 |
COMPOSITIONS AND METHODS FOR LONG TERM RELEASE OF GONADOTROPIN-RELEASING
HORMONE (GnRH) ANTAGONISTS The invention provides compositions and methods for long term release of Gonadotropin-releasing hormone (GnRH) antagonists and uses thereof. Specifically, the... |
| 2018/0250353 |
CEACAM BASED ANTIBACTERIAL AGENTS Prophylactic and/or therapeutic antipathogen agents are provided that disrupt or prevent the formation of at least one homotypic and/or heterotypic... |
| 2018/0250352 |
TREATMENT OF CANCER BY INFUSION OF ONCOLYTIC HERPES SIMPLEX VIRUS TO THE
BLOOD An oncolytic herpes simplex virus is disclosed for use in a method of treating cancer in a human subject, the method comprising administering to the human... |
| 2018/0250351 |
Cyanobacterial microalgae phycocyanin and phycocyanobilin to beneficially
inhibit the activity of the UDP-GDH... The present invention provides a method for inhibiting the UDP-GDH enzyme, which has in itself important beneficial implications, thus strongly enhancing the... |
| 2018/0250350 |
PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING INFLAMMATORY BOWEL
DISEASES The present invention relates to methods and pharmaceutical compositions for preventing or treating inflammatory bowel diseases. |
| 2018/0250349 |
METHODS AND COMPOSITIONS USING BIFIDOBACTERIUM LONGUM TO MODULATE
EMOTIONAL REACTIVITY AND TREAT OR PREVENT... Compositions and methods use Bifidobacterium longum NCC3001 (ATCC BAA-999) to stabilize or improve mood, modulate excessive emotional distress, reduce anxiety,... |
| 2018/0250348 |
METHODS AND COMPOSITIONS USING BIFIDOBACTERIUM LONGUM TO TREAT OR PREVENT
DEPRESSIVE SYMPTOMS Compositions and methods use Bifidobacterium longum NCC3001 (ATCC BAA-999) to treat or prevent a depressive symptom. Prolonged anti-depressive effects can... |
| 2018/0250347 |
USE OF PASTEURIZED AKKERMANSIA FOR TREATING METABOLIC DISORDERS The present invention relates to pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The... |
| 2018/0250346 |
COMPOSITIONS COMPRISING BACTERIAL STRAINS The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases. |
| 2018/0250345 |
VEGFR-2 TARGETING DNA VACCINE FOR COMBINATION THERAPY The present invention relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding a... |
| 2018/0250344 |
LITHIUM STIMULATION OF CORD BLOOD STEM CELL PROLIFERATION AND GROWTH
FACTOR PRODUCTION The present invention provides methods for expanding human umbilical cord blood stem cells and methods for stimulating growth factor production by cord blood... |
| 2018/0250343 |
THERAPEUTIC COMPOSITIONS A therapeutic composition can include an amount of amniotic fluid having a therapeutically effective amount of at least one protein, hyaluronic acid, or both.... |
| 2018/0250342 |
MODULATION OF SPLENOCYTES IN CELL THERAPY The invention provides methods for treating pathological conditions associated with an undesirable inflammatory component. The invention is generally directed... |
| 2018/0250341 |
METHOD OF REPAIRING DAMAGED BLOOD-SPINAL CORD BARRIER (BSCB) The disclosure provides methods of administering a composition comprising human bone marrow CD34+ (hBM34+) cells to a mammal in need thereof, whereby vascular... |
| 2018/0250340 |
METHODS FOR REJUVINATING RED BLOOD CELLS Methods and a system for transfusing blood to a mammalian subject. The method includes obtaining a volume of donated red blood cells (RBCs), adding an... |
| 2018/0250339 |
METHODS AND COMPOSITIONS FOR GENE EDITING IN HEMATOPOIETIC STEM CELLS The present invention relates to compositions and methods of generating modified hematopoietic stem or progenitor cells. One aspect of the invention includes a... |
| 2018/0250338 |
TUMOR INFILTRATING LYMPHOCYTES FOR TREATMENT OF CANCER Tumor infiltrating lymphocytes (TILs) are white blood cells that are actively recruited to the tumor site to mount an immune response against tumor growth and... |
| 2018/0250337 |
GENETICALLY ENGINEERED DRUG RESISTANT T CELLS AND METHODS OF USING THE
SAME The present disclosure provides novel cell compositions engineered to express at least a chimeric antigen receptor and a survival factor. Methods of using such... |
| 2018/0250336 |
COMPOSITIONS AND METHODS OF ENHANCING ANTI-TUMOR RESPONSE USING HYBRID
NEUTROPHILS The present invention relates to compositions and methods that provide novel anti-tumor therapies in cancer. In one aspect, the present invention features a... |
| 2018/0250335 |
MODIFIED CELLS EVOKING REDUCED IMMUNOGENIC RESPONSES Embodiments of this disclosure relate to techniques and systems for preparing modified cells evoking reduced immunogenic responses and application thereof. For... |
| 2018/0250334 |
TRACE ELEMENTS A trace element solution comprises at least the following metals: zinc; manganese; selenium; and copper; and which comprises a concentration of the metals of... |
| 2018/0250333 |
Nanoceria For The Treatment of Oxidative Stress A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and... |
| 2018/0250332 |
Polymer Conjugate Of Hexa-Coordinated Platinum Complex A DDS preparation of a platinum complex, which selectively releases a highly active platinum complex in cells that are under reducing conditions, and exhibits... |
| 2018/0250331 |
Method for Poly Signal Activation of Apoptosis of Malignant Solid Tumour
Cells The invention relates to medicine and concerns a method for the poly signal activation of apoptosis of malignant solid tumour cells, carried out by means of... |
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