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Patent # Description
2018/0250380 TREATMENT OF PIGS WITH PCV2 ANTIGEN
The present invention relates to a method for the treatment or prophylaxis of a PCV2 infection or for reduction of clinical symptoms caused by or associated...
2018/0250379 GENERATION OF HPV-SPECIFIC T-CELLS
Embodiments of the disclosure concern methods and compositions for immunotherapy for human papillomavirus infection and diseases associated therewith. In...
2018/0250378 COMBINATION OF THERAPEUTIC VACCINE AND PD-1-RELATED BLOCKADE FOR TREATING HUMAN PAPILLOMAVIRUS-ASSOCIATED DISEASES
The present disclosure relates to an immunostimulatory combination comprising a therapeutic vaccine and a PD-1-related blockade for treating human...
2018/0250377 BACILLUS BASED DELIVERY SYSTEM AND METHODS OF USE
Herein a Bacillus exosporium antigen delivery (BEAD) system that provides a means to introduce recombinant proteins or small molecules into the exosporium of...
2018/0250376 MODIFIED ANTHRAX TOXIN PROTECTIVE ANTIGEN
Disclosed is a Bacillus anthracis protective antigen (PA) comprising a PA amino acid sequence, wherein one or more of amino acid residues I207, I210, E654,...
2018/0250375 NOVEL METHODS FOR INDUCING AN IMMUNE RESPONSE
The present invention relates to methods for inducing an immune response, in particular methods for inducing an immune response against mycobacterial...
2018/0250374 NOVEL PEPTIDES, COMBINATION OF PEPTIDES AND SCAFFOLDS FOR USE IN IMMUNOTHERAPEUTIC TREATMENT OF VARIOUS CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2018/0250373 NOVEL PEPTIDES, COMBINATION OF PEPTIDES AND SCAFFOLDS FOR USE IN IMMUNOTHERAPEUTIC TREATMENT OF VARIOUS CANCERS
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates...
2018/0250372 COMPOSITIONS FOR TREATING AN ARTHRITIC CONDITION
Methods for treating an arthritic condition in a subject by administering to the subject at least one human Tr1 cell population directed to a joint-associated...
2018/0250371 CRYSTALLIZED OXALATE DECARBOXYLASE AND METHODS OF USE
Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a...
2018/0250370 TREATMENT OF RETINITIS PIGMENTOSA USING ENGINEERED MEGANUCLEASES
Disclosed are recombinant meganucleases engineered to recognize and cleave recognition sequences present in a mutant RHO P23H allele. The invention further...
2018/0250369 LACTOFERRIN COMPOSITIONS AND METHODS FOR MODULATION OF T CELL SUBTYPES AND TREATMENT OF AUTOIMMUNE DISEASES
Provided herein are improved compositions comprising lactoferrin and methods for modulating T cell subtypes and their activities in a subject, to improve the...
2018/0250368 LIQUID COMPOSITION OF HUMAN ALBUMIN FOR THERAPEUTIC USE
Disclosed is a liquid composition of human albumin for therapeutic use, in which at least 50% of the albumin has a molecular weight of 66.438 Da, plus or minus...
2018/0250367 POLYMER-FACTOR VIII MOIETY CONJUGATES
Conjugates of a Factor VIII moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a...
2018/0250366 COMPOSITIONS AND METHODS FOR PROTECTING THE KIDNEY FROM ISCHEMIA REPERFUSION INJURY
The effects of hepcidin treatment on mitigating IRI and acute kidney injury by decreasing iron availability and ROS-mediated cell death were tested. C57Bl/6...
2018/0250365 ACTH FOR TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
Provided herein are methods of treatment of Amyotrophic Lateral Sclerosis comprising administration of adrenocorticotropic hormone (ACTH), or fragment, analog,...
2018/0250364 Methods of Using Interleukin-10 for Treating Diseases and Disorders
Methods of treating subjects having a disease or disorder responsive to IL-10, including methods of administration and dosing regimens associated therewith,...
2018/0250363 Pegylated Interleukin-10
Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for...
2018/0250362 Methods of Treating Fungal Infections
The invention relates to methods of treating a fungal infection in a subject in need thereof comprising administering to the subject a therapeutically...
2018/0250361 Methods, Compounds and Compositions for Modulating Blood Brain Barrier Integrity and Re-myelination
Disclosed herein are methods and compositions for increasing and decreasing the permeability of the blood brain barrier for the treatment of diseases and...
2018/0250360 METHOD FOR DETECTING CANCER CELLS, REAGENT FOR INTRODUCING SUBSTANCE INTO CANCER CELLS, AND COMPOSITION FOR...
As a technique for specifically detecting cancer cells, provided is a method for detecting cancer cells, including the steps of: bringing BC2LCN lectin into...
2018/0250359 COMBINATION THERAPY USING GLIADIN AND GAMMA AMINOBUTYRIC ACID
The present invention relates to the use of gliadin in medicine, in combination with gamma aminobutyric acid, and/or an antigen such as a beta cell autoantigen.
2018/0250358 GHRH AGONISTS FOR THE TREATMENT OF ISCHEMIC DISORDERS
Disclosed herein are compositions of GHRH agonists and peptides, and methods to treat disorders, such as ischemia and reperfusion injury. In one embodiment, a...
2018/0250357 METHODS COMPRISING DESMOPRESSIN
The present disclosure is directed to gender, age, and dose effects of desmopressin on reducing nocturnal voids, increasing an initial period of undisturbed...
2018/0250356 TARGETING G3BP PROTEINS TO ACCELERATE NERVE REGENERATION
Methods for using a peptide to effectively increase axon growth in both naive and injury-conditioned neurons.
2018/0250355 COMPOSITIONS AND METHODS FOR IMPROVING SEXUAL FUNCTION
The embodiments include methods of improving sexual function in a male with benign prostatic hyperplasia (BPH), using compositions containing compounds based...
2018/0250354 COMPOSITIONS AND METHODS FOR LONG TERM RELEASE OF GONADOTROPIN-RELEASING HORMONE (GnRH) ANTAGONISTS
The invention provides compositions and methods for long term release of Gonadotropin-releasing hormone (GnRH) antagonists and uses thereof. Specifically, the...
2018/0250353 CEACAM BASED ANTIBACTERIAL AGENTS
Prophylactic and/or therapeutic antipathogen agents are provided that disrupt or prevent the formation of at least one homotypic and/or heterotypic...
2018/0250352 TREATMENT OF CANCER BY INFUSION OF ONCOLYTIC HERPES SIMPLEX VIRUS TO THE BLOOD
An oncolytic herpes simplex virus is disclosed for use in a method of treating cancer in a human subject, the method comprising administering to the human...
2018/0250351 Cyanobacterial microalgae phycocyanin and phycocyanobilin to beneficially inhibit the activity of the UDP-GDH...
The present invention provides a method for inhibiting the UDP-GDH enzyme, which has in itself important beneficial implications, thus strongly enhancing the...
2018/0250350 PHARMACEUTICAL COMPOSITIONS FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASES
The present invention relates to methods and pharmaceutical compositions for preventing or treating inflammatory bowel diseases.
2018/0250349 METHODS AND COMPOSITIONS USING BIFIDOBACTERIUM LONGUM TO MODULATE EMOTIONAL REACTIVITY AND TREAT OR PREVENT...
Compositions and methods use Bifidobacterium longum NCC3001 (ATCC BAA-999) to stabilize or improve mood, modulate excessive emotional distress, reduce anxiety,...
2018/0250348 METHODS AND COMPOSITIONS USING BIFIDOBACTERIUM LONGUM TO TREAT OR PREVENT DEPRESSIVE SYMPTOMS
Compositions and methods use Bifidobacterium longum NCC3001 (ATCC BAA-999) to treat or prevent a depressive symptom. Prolonged anti-depressive effects can...
2018/0250347 USE OF PASTEURIZED AKKERMANSIA FOR TREATING METABOLIC DISORDERS
The present invention relates to pasteurized Akkermansia muciniphila or fragments thereof for treating a metabolic disorder in a subject in need thereof. The...
2018/0250346 COMPOSITIONS COMPRISING BACTERIAL STRAINS
The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
2018/0250345 VEGFR-2 TARGETING DNA VACCINE FOR COMBINATION THERAPY
The present invention relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding a...
2018/0250344 LITHIUM STIMULATION OF CORD BLOOD STEM CELL PROLIFERATION AND GROWTH FACTOR PRODUCTION
The present invention provides methods for expanding human umbilical cord blood stem cells and methods for stimulating growth factor production by cord blood...
2018/0250343 THERAPEUTIC COMPOSITIONS
A therapeutic composition can include an amount of amniotic fluid having a therapeutically effective amount of at least one protein, hyaluronic acid, or both....
2018/0250342 MODULATION OF SPLENOCYTES IN CELL THERAPY
The invention provides methods for treating pathological conditions associated with an undesirable inflammatory component. The invention is generally directed...
2018/0250341 METHOD OF REPAIRING DAMAGED BLOOD-SPINAL CORD BARRIER (BSCB)
The disclosure provides methods of administering a composition comprising human bone marrow CD34+ (hBM34+) cells to a mammal in need thereof, whereby vascular...
2018/0250340 METHODS FOR REJUVINATING RED BLOOD CELLS
Methods and a system for transfusing blood to a mammalian subject. The method includes obtaining a volume of donated red blood cells (RBCs), adding an...
2018/0250339 METHODS AND COMPOSITIONS FOR GENE EDITING IN HEMATOPOIETIC STEM CELLS
The present invention relates to compositions and methods of generating modified hematopoietic stem or progenitor cells. One aspect of the invention includes a...
2018/0250338 TUMOR INFILTRATING LYMPHOCYTES FOR TREATMENT OF CANCER
Tumor infiltrating lymphocytes (TILs) are white blood cells that are actively recruited to the tumor site to mount an immune response against tumor growth and...
2018/0250337 GENETICALLY ENGINEERED DRUG RESISTANT T CELLS AND METHODS OF USING THE SAME
The present disclosure provides novel cell compositions engineered to express at least a chimeric antigen receptor and a survival factor. Methods of using such...
2018/0250336 COMPOSITIONS AND METHODS OF ENHANCING ANTI-TUMOR RESPONSE USING HYBRID NEUTROPHILS
The present invention relates to compositions and methods that provide novel anti-tumor therapies in cancer. In one aspect, the present invention features a...
2018/0250335 MODIFIED CELLS EVOKING REDUCED IMMUNOGENIC RESPONSES
Embodiments of this disclosure relate to techniques and systems for preparing modified cells evoking reduced immunogenic responses and application thereof. For...
2018/0250334 TRACE ELEMENTS
A trace element solution comprises at least the following metals: zinc; manganese; selenium; and copper; and which comprises a concentration of the metals of...
2018/0250333 Nanoceria For The Treatment of Oxidative Stress
A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and...
2018/0250332 Polymer Conjugate Of Hexa-Coordinated Platinum Complex
A DDS preparation of a platinum complex, which selectively releases a highly active platinum complex in cells that are under reducing conditions, and exhibits...
2018/0250331 Method for Poly Signal Activation of Apoptosis of Malignant Solid Tumour Cells
The invention relates to medicine and concerns a method for the poly signal activation of apoptosis of malignant solid tumour cells, carried out by means of...
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