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Patent # Description
2018/0251746 MODIFIED CASPASE POLYPEPTIDES AND USES THEREOF
The technology relates in part to compositions comprising modified Caspase-9 polypeptides, compositions comprising nucleic acids coding for modified Caspase-9...
2018/0251745 Compositions and Methods for Modulating Hemostasis
Factor Xa variants and methods of use thereof are disclosed.
2018/0251744 FACTOR IX VARIANTS WITH CLOTTING ACTIVITY IN ABSENCE OF THEIR COFACTOR AND/OR WITH INCREASED F.IX CLOTTING...
The present invention relates to variants of factor IX (F.IX) or activated factor IX (F.IXa), wherein the variant is characterized in that it has clotting...
2018/0251743 SERINE PROTEASES OF BACILLUS SPECIES
The present disclosure relates to serine proteases cloned from Bacillus Akibai and Bacillus Clarkii, and variants thereof. Compositions containing the serine...
2018/0251742 THERMOLYSIN VARIANTS
The present invention provides methods and compositions comprising at least one thermolysin-like neutral protease enzyme with improved storage stability and/or...
2018/0251741 METHOD FOR PRODUCING BOTULINUM TOXIN
The present invention relates to a method for producing a botulinum toxin comprising:(a) treating a culture of a botulinum toxin-producing strain with acid to...
2018/0251740 COMPOSITIONS AND METHODS FOR TREATMENT OF PAIN
Embodied herein are engineered fusion proteins that bind and target nociceptor neurons, compositions comprising these engineered fusion proteins, and methods...
2018/0251739 METHODS FOR SCREENING AND USING CRISPR/CAS9 GUIDANCE RNA SEQUENCE FROM HIV PROVIRUS GENOME
The invention pertains to compositions and methods for identifying gRNAs that are effective in treating a latent HIV infection. An embodiment of the invention...
2018/0251738 INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES
The present invention relates to the production of chemical species in bacterial host cells. Particularly, the present invention provides for the production of...
2018/0251737 COMPOSITIONS, METHODS AND USES FOR INDUCING VIRAL GROWTH
Embodiments herein report methods, compositions and uses for inducing and/or accelerating viral growth. In certain embodiments, methods, compositions and uses...
2018/0251736 SYNTHETIC CHIMERIC POXVIRUSES
The invention relates, in general, to synthetic chimeric poxviruses, compositions comprising such viruses, and the development and use of systems and methods...
2018/0251735 Compositions And Methods For Differentiation Of Human Pluripotent Stem Cells Into Desired Cell Types
In related-art methods of differentiating pluripotent stem cells into a desired cell type, there has not been established a differentiation induction method...
2018/0251734 AN IN VITRO METHOD OF DIFFERENTIATING A HUMAN PLURIPOTENT STEM CELL POPULATION INTO A CARDIOMYOCYTE CELL POPULATION
The current invention relates to a method of differentiation of human pluripotent stem cells into a human stem-cell derived population of cardiomyocytes. The...
2018/0251733 BASE MATERIAL FOR CELL CULTURE AND CELL CULTURE METHOD USING SAME, CELL CULTURE CONTAINER, AND USE AS BASE MATERIAL
The present invention provides a base material for cell culture comprising a polyester resin comprising a dicarboxylic acid unit and a diol unit, wherein 1 to...
2018/0251732 NOVEL METHOD FOR CHONDROGENIC INDUCTION
Provided is a method for producing chondrocytes from pluripotent stem cells, the method comprising the steps of: (i) culturing pluripotent stem cells under...
2018/0251731 SUBPOPULATION OF CD8+CD45RCLOW TREGS AND USES THEREOF
Disclosed is a new subpopulation of CD8.sup.+CD45RC.sup.low Tregs, namely IFN.gamma..sup.+IL-10.sup.+IL-34.sup.+ secreting population of ...
2018/0251730 COMPOSITIONS AND METHODS FOR GENERATING OLIGODENDROCYTE PRECURSORS
The present disclosure provides a three-dimensional culture system comprising a biocompatible polymer and a combination of factors in an amount effective to...
2018/0251729 CULTURE METHOD FOR DIFFERENTIATING PRIMORDIAL GERM CELLS INTO FUNCTIONALLY MATURE OOCYTES
A problem of this invention it to provide a method for differentiate a primordial germ cell into a functional GV stage oocyte by in vitro culture. This...
2018/0251728 ANDROGENETIC HAPLOID EMBRYONIC STEM CELL, AND PREPARATION METHOD AND USE THEREOF
The present invention relates to an AG-haESCs in which H19 DMR and IG-DMR are knocked out, a method for preparing the AG-haESCs, and use of the AG-haESCs in...
2018/0251727 TISSUE-ENGINEERED CONSTRUCTS
The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular...
2018/0251726 MICROWELL PLATE WITH LAMINATED MICRO EMBOSSED FILM BOTTOM
The current disclosure describes a method of fabricating a n.times.n where n=1 to 100 micro well plate that has a transparent film bottom where the film has...
2018/0251725 SYSTEMS AND METHODS FOR ENRICHING A BACTERIAL STRAIN FROM A TARGET BACTERIAL SYSTEM
The present invention is a method of enriching at least one bacterial species from a target bacterial system, including: culturing the target bacterial...
2018/0251724 METHOD FOR AFFECTING PHENOTYPIC ACTIVITY OF ENDOPHYTIC FUNGI
Described herein are methods for the alteration and/or transfer of fungal functional traits, e.g., phenotypic activity, via the controlled transfer of...
2018/0251723 Systems For Producing Cellular Immunotherapeutics And Methods Of Use Thereof
Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from...
2018/0251722 Improvements in and Relating to Biomanufacturing Apparatus
Disclosed is a biomanufacturing apparatus (1) comprising a housing (20) including top (22) and bottom (24) faces which allow stacking of plural housings, an...
2018/0251721 CELL CULTURE MODULE
A cell culture module includes a cell culture substrate that has, on a surface thereof, a recessed portion that cultures a cell, in which at least a bottom...
2018/0251720 METHOD FOR HUMIDIFYING AN INCUBATOR, AND INCUBATOR
A method for the regulated humidification and temperature control of a gas mixture in an inner chamber of an incubator, which inner chamber is sealed off from...
2018/0251719 MECHANICAL BIOREACTOR
A mechanical bioreactor for transferring vibrations to cell cultures for the purpose of stimulating various biological processes across a relatively large...
2018/0251718 METHOD AND BIOREACTOR FOR PRODUCING A CULTURE OF MICROORGANISMS
A bioreactor (1) is described of producing a culture of microorganisms (4) comprising at least one cylindrical container (2) and shaking and mixing means (11)...
2018/0251717 3D POLYMERIC INSERT TO APPLY UNIFORM ELECTRIC FIELD IN CIRCULAR CULTUREWARE
A disclosed insert for a circular-shaped petri dish can generate a substantially uniform electric field across the petri dish that is filled with a fluid...
2018/0251716 BIOREACTOR SYSTEM AND METHOD FOR PRODUCING A BIOPOL YMER
Provided is a bioreactor system and a fermentation process employing continuous inline medium dilution in which concentrated medium and nutrients are blended...
2018/0251715 Improvements in and Relating to Biomanufacturing Apparatus
Disclosed is biomanufacturing apparatus 1 comprising a housing 20 including top 22 and bottom 24 faces which allow stacking of plural housings, an access door...
2018/0251714 Tissue Fragment
Provided is a method for producing a tissue-like construct having cultured cells organized in an aligned manner, especially, a cardiac tissue-like construct....
2018/0251713 Field-deployable Multiplexed Sampling and Monitoring Device and Bacterial Contamination Measurement Method
A system for processing samples from a body of fluid. The system includes one or more sample bottles for acquiring a sample from the body of fluid. Each sample...
2018/0251712 POST CHEMICAL MECHANICAL POLISHING FORMULATIONS AND METHOD OF USE
A cleaning composition and process for cleaning post-chemical mechanical polishing (CMP) residue and contaminants from a microelectronic device having said...
2018/0251711 TiN Hard Mask and Etch Residue Removal
Composition, method and system for PVD TiN hard mask removal from 28/20 nm pattern wafers have been disclosed. The composition uses peroxide as oxidizing agent...
2018/0251709 METHOD FOR PRODUCING POLYASPARTIC ACID UNDER REFLUX COOLING
Provided herein is a method for producing polyaspartic acid under reflux cooling. Further provided herein are compositions including polyaspartic acid...
2018/0251708 HARD SURFACE CLEANING COMPOSITIONS COMPRISING PHOSPHINOSUCCINIC ACID ADDUCTS AND METHODS OF USE
Methods employing detergent compositions effective for reducing hard water scale and accumulation on hard surfaces, namely within food, beverage and...
2018/0251707 Gutter Cleaning Composition and Method
Cleaning compositions including one or more non-ionic surfactants; one or more quaternary ammonium compounds; at least one citrus terpene; one or more...
2018/0251706 ORGANIC COMPOUNDS
An aryl-substituted alkanal compound having a molecular weight of less than 300 g/mol and which bears a substituent on the aryl ring ortho to a substituent...
2018/0251705 FRAGRANCE MIXTURES
Suggested is a fragrance mixture comprising specific esters of (-)-carveol and/or (-)-dihydro-carveol.
2018/0251704 COMPOSITIONS AND METHODS FOR OIL DEGUMMING
The present disclosure provides compositions and methods for enzymatic oil degumming.
2018/0251703 Compositions for Engine Carbon Removal from Lubricated components
The engine lubricating system can become contaminated with carbon deposits and sludge. Sludge is where the combustion by-products that have entered the oil...
2018/0251702 ESTOLIDE COMPOSITIONS EXHIBITING SUPERIOR HIGH-PERFORMANCE PROPERTIES
Compounds and compositions, including engine oils and lubricant formulations comprising at least one estolide compound. Exemplary compositions comprise an...
2018/0251701 Viscosity Index Improver Concentrates
A viscosity index improver containing, in non-ester diluent oil, one or more hydrogenated, functionalized linear block copolymers having at least one block...
2018/0251700 LUBRICATING OIL COMPOSITIONS
A lubricating oil composition, a method of reducing low-speed pre-ignition (LSPI) in a direct-injected spark-ignited internal combustion engine, and a use of a...
2018/0251699 POWDER LUBRICANT BASED ON FATTY ACIDS AND FATTY ACID GLYCERIDES AND USE THEREOF
A dry lubricant composition in powder form is provided based on a mixture of alkali metal salts of fatty acids and fatty acid glycerides which is useful in the...
2018/0251698 Lubricant Composition
A lubricant composition includes a base oil present in an amount of greater than 70 parts by weight per 100 parts by weight of the lubricant composition and an...
2018/0251697 Lubricant Composition
A lubricant composition includes a base oil present in an amount of greater than 70 parts by weight per 100 parts by weight of the lubricant composition and an...
2018/0251696 LUBRICATING OIL COMPOSITIONS CONTAINING AMINE COMPOUNDS HAVING IMPROVED SEAL PERFORMANCE
Provided is an internal combustion engine lubricating oil composition which comprises a major amount of an oil of lubricating viscosity; one or more oil...
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