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Patent # Description
2018/0251442 PROCESSES AND INTERMEDIATES FOR THE PREPARATIONS OF ISOMER FREE PROSTAGLANDINS
Novel processes for the preparation of a compound of Formula I-2 substantially free of the 5,6-trans isomer: ##STR00001## wherein ##STR00002## R.sub.2,...
2018/0251441 ION-ACTIVATED PHOTOLABILE COMPOUNDS
The presently-disclosed subject matter relates to analyte-activated photolabile compounds. The compounds include the formula: wherein Z includes a maskable...
2018/0251440 DERIVATIVE OF INULA LINEARIIFOLIA LACTONE A
A derivative of inula lineariifolia lactone A, and in particular, a dimethylamine 4-O-acetyl inula lineariifolia lactone A or a salt thereof, preparation of...
2018/0251439 Process to Prepare Hydroxymethylfurfural Derivatives
The invention relates generally to the preparation of hydroxymethyl furfural derivatives such as 5-carboxymethyl furfural derivatives, ethers such as...
2018/0251438 PROCESS FOR THE PRODUCTION OF 1,4-BUTANEDIOL AND TETRAHYDROFURAN FROM FURAN
The present invention provides a process for the production of 1,4-BDO and THF from furan, said process comprising: (i) contacting furan with hydrogen and...
2018/0251437 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL...
The present invention relates to novel compounds represented by the formula I having histone deacetylase 6 (HDAC6) inhibitory activity, stereoisomers thereof...
2018/0251436 CERTAIN (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE 1 INHIBITORS
The present disclosure relates to certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable...
2018/0251435 COMPOUNDS FOR THERAPEUTIC USE
Chemical entities of Formula (I): ##STR00001## Including enantiomers thereof, wherein R.sup.1 has any of the values described herein, and compositions comprising...
2018/0251434 ANTIBACTERIAL HETEROCYCLIC DERIVATIVES
The invention relates to antibacterial compounds of formula I ##STR00001## wherein R.sup.1, M, R.sup.2, R.sup.3, and V are as described in the description, to...
2018/0251433 Novel formulation of metaxalone
The present invention relates to methods for producing particles of metaxalone using dry milling processes as well as compositions comprising metaxalone,...
2018/0251432 Novel Amino Pyrimidine Derivatives
The present invention describes new amino pyrimidine derivatives and pharmaceutically acceptable salts thereof which appear to interact with Bruton's tyrosine...
2018/0251431 1,3-SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL FOR REDUCTION OF VERY LONG CHAIN FATTY ACID LEVELS
Disclosed are chemical entities which are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein Formula (I) has the structure, ...
2018/0251430 1-(4-(2-((1-(3,4-DIFLUOROPHENYL)-1H-PYRAZOL-3-YL)METHOXY)ETHYL)PIPERAZIN-1- -YL)ETHANONE SALTS
The present invention relates to 1-(4-(2-((1-(3,4-difluorophenyl)-1 H-pyrazol-3-yl)methoxy)ethyl)piperazin-1-yl)ethanone salts, specifically to the...
2018/0251429 FARNESOID X RECEPTOR AGONISTS AND USES THEREOF
Described herein are compounds that are farnesoid X receptor agonists, methods of making such compounds, pharmaceutical compositions and medicaments comprising...
2018/0251428 METHOD FOR THE PRODUCTION OF PRAZIQUANTEL AND PRECURSORS THEREOF
The present invention provides methods of preparing Praziquantel, in particular (R)-Praziquantel and analogues thereof in a stereoselective manner. One method...
2018/0251427 Transition Metal-catalyzed Protocarboxylation of alpha-Halo-acrylic Acid Derivatives
The present invention relates to a method for the synthesis of a halo olefin of formula (I) ##STR00001## wherein Hal, R.sup.1, R.sup.2, R.sup.3, R.sup.4, X and Y...
2018/0251426 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases...
2018/0251425 2,3,5 TRISUBSTITUTED PYRROLE DERIVATIVES AS TOPOISOMERASE INHIBITORS AND THERAPEUTIC USES THEREOF
The compounds of Formula (1) having topoisomerase inhibitory effect includes ##STR00001## wherein, R1 is selected from a group consisting of H, OR5, optionally ...
2018/0251424 Method for Producing Alpha-substituted Cysteine or Salt Thereof or Synthetic Intermediate of Alpha-substituted...
According to the present invention, it becomes possible to perform a process for converting into an .alpha.-substituted cysteine represented by general formula...
2018/0251423 1-SULFONAMIDO-4-ARYLOXY COMPOUNDS, AND PREPARATION METHOD AND MEDICINAL APPLICATION THEREOF
Compounds of formula (I) having 1-sulfonamido-4-aryloxy as a basic backbone. A preliminary activity test showed that the compounds provide excellent...
2018/0251422 FORMULATIONS WITH IMPROVED STABILITY
Formulations containing pharmaceutically active compounds with improved stability.
2018/0251421 NOVEL BETA-HYDROXYLATED TERTIARY DIAMINES, A PROCESS FOR THEIR SYNTHESIS AND THEIR USE FOR ELIMINATING ACID...
The invention relates to novel nitrogen compounds belonging to the family of tertiary diamines of general formula (I) below, wherein R is an alkanediyl radical...
2018/0251420 METHOD FOR PREPARATION OF N-BUTYL NITRITE
The invention discloses a method for the continuous preparation of n-butyl nitrite with a low content of n-butanol comprising the reaction of n-butanol, an...
2018/0251419 EXTRACTIVE WORKUP OF A SODIUM-SALT-CONTAINING MMA-METHANOL MIXTURE
The present invention relates to a process for preparing methyl methacrylate by direct oxidative esterification of methacrolein. Methyl methacrylate is used in...
2018/0251418 SYNTHESIS OF METHACRYLIC ACID FROM METHACROLEIN-BASED ALKYL METHACRYLATE
The present invention relates to a process for preparing alkyl methacrylates, especially MMA, and methacrylic acid, based on methacrolein, which has been...
2018/0251417 A PROCESS FOR PREPARATION OF 1-[2-(DIMETHYL AMINO)-1-(4-HYDROXYPHENYL) ETHYL]-CYCLOHEXANOL AND SALTS THEREOF
A high yield process of preparation of, [1-[2-(Dimethylamino)-1-(4-hydroxyphenyl)ethy]-cyclohexanol] through potassium hydroxide mediated demethylation of...
2018/0251416 PROCESS FOR THE PREPARATION OF OLEFIN CONTAINING FLUORINE
The present invention relates to a process for preparation of olefins containing fluorine.
2018/0251415 METHOD FOR MAKING 1,1,3,3-TETRACHLOROPROPENE
A process for the manufacture of 1,1,3,3-tetrachloropropene, the process comprising dehydrochlorinating 1,1,1,3,3-pentachloropropane.
2018/0251414 PROCESS FOR PRODUCING HYDROFLUOROOLEFIN
A method for producing a hydrofluoroolefin is provided. The formation of by-products of an over-reduced product having hydrogen added to a material...
2018/0251413 Transalkylation Processes and Catalyst Compositions Used Therein
Disclosed are selectivated transalkylation catalyst compositions and methods of making the same. The selectivated transalkylation catalyst compositions have a...
2018/0251412 HEAT RECOVERY IN THE PROCESS OF PRODUCTION OF BUTADIENE
The process to recover heat in oxidative dehydrogenation of butene to butadiene is presented. The process utilizes heat recovered in oxidative dehydrogenation...
2018/0251411 PROCESS FOR MAKING RENEWABLE SURFACTANT INTERMEDIATES AND SURFACTANTS FROM FATS AND OILS AND PRODUCTS THEREOF
The present invention relates generally to methods for producing renewable detergent compounds. More specifically, the invention relates to methods for...
2018/0251410 SELECTIVE OLIGOMERIZATION OF OLEFINS
The invention relates to a catalyst system for oligomerizing olefins over a catalyst comprising nickel, to the use of this catalyst and to a method for...
2018/0251409 HIGH EFFICIENCY FUEL CELL
Fuel cell arrangement having an improved efficiency. The arrangement comprises one or more fuel cell units 110 and a methanation unit 200 and a control unit...
2018/0251408 Slow-Release Fertilizer Composition and Preparation Method
A method of making the slow-release fertilizer and the composition thereof includes the steps of adding Class A Exceptional Quality biosolids at a...
2018/0251407 PRECURSORS FOR CARBON-CARBON COMPOSITES
The present invention provides a precursor curable composition including (a) at least one first epoxy resin; (b) at least one latent catalyst, (c) optionally,...
2018/0251406 SINTERED CERAMIC PROTECTIVE LAYER FORMED BY HOT PRESSING
Disclosed herein are methods for fabricating layered ceramic materials via hot pressing. A method includes disposing a powder compact or a ceramic slurry onto...
2018/0251405 DIELECTRIC CERAMIC COMPOSITION
A dielectric ceramic composition includes a first inorganic component having a trigonal ditrigonal pyramidal crystal structure, a second inorganic component...
2018/0251404 Use of calcium sulfate in an inorganic mortar system based on aluminous cement to increase load values
An inorganic mortar system for a chemical fastening of an anchor in a mineral surface includes calcium sulfate, a component A, and a component B for initiating...
2018/0251403 COMPOSITIONS AND METHODS FOR WELL CEMENTING
A method for well cementing may include supplying a settable composition including a cement composition and water into a well bore, and allowing the settable...
2018/0251402 MASONRY BLOCKS
Crumb Rubber augmented masonry blocks including cement, aggregate, water, and crumb rubber. Crumb rubber is extracted from scrape tires after being processed...
2018/0251401 CEMENT ADDITIVE, CEMENT COMPOSITION, AND CEMENT ADDITIVE RAW MATERIAL
Provided is a cement additive that can suppress the production of Glauber's salt as a by-product, and that can express excellent retention when turned into a...
2018/0251400 ASYMMETRIC STRESS PROFILES FOR LOW WARP AND HIGH DAMAGE RESISTANCE GLASS ARTICLES
A glass article having an asymmetric stress profile exhibiting a high degree of asymmetry and a low degree or no warp. The glass article has a stress profile...
2018/0251399 ANTIMICROBIAL-ANTIREFLECTIVE ARTICLES AND METHODS FOR MAKING THE SAME
Described herein are antimicrobial articles having improved antimicrobial efficacy and antireflective properties. Further described are methods of making and...
2018/0251398 DISPLAY COVER MEMBER AND PRODUCTION METHOD THEREFOR
Provided is a display cover member that enables realization of a display having less reflection of the background and excellent anti-sparkle properties. The...
2018/0251397 OPTICAL FIBER WITH LOW LOSS AND NANOSCALE STRUCTURALLY HOMOGENEOUS CORE
An optical fiber has a core region that is doped with one or more viscosity-reducing dopants in respective amounts that are configured, such that, in a Raman...
2018/0251396 PROCESS FOR PRODUCING GRANULAR PELLETIZED GLASS MATERIAL WITH TRACE ELEMENTS, ESPECIALLY AS GROWTH SUPPORT FOR...
A pelletized expanded glass material is provided, which is particularly suitable as a growth support for microorganisms, especially for use in a biogas plant...
2018/0251395 OPTICAL GLASS
Provided is an optical glass suitable for an imaging lens or the like used for a vehicle-mounted camera exposed to harsh environment, having a high refractive...
2018/0251394 METHOD AND SYSTEM FOR REDUCING AGGLOMERATES IN A GLASS MELT
Disclosed herein are methods for making glass, comprising forming a slurry comprising at least one fining agent; adjusting the pH of the slurry to a value...
2018/0251393 WIRE-DRAWING OPTICAL FIBER BASE MATERIAL MANUFACTURING METHOD AND MANUFACTURING APPARATUS
A wire-drawing optical fiber base material manufacturing method of heating an optical fiber base material by a heater and forming a drawing shape portion at an...
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