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Patent # Description
2018/0305745 SYSTEMIC LUPUS ERYTHEMATOSUS BIOMARKER AND DIAGNOSTIC KIT THEREOF
Disclosed are a systemic lupus erythematosus (SLE) biomarker and diagnostic kit thereof. The SLE biomarker is a segment within 1500 bp upstream from a...
2018/0305744 METHOD FOR SIMULTANEOUS SEQUENCE-BASED TYPING OF 14 FUNCTIONAL KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR (KIR) GENES
Based on the structural features of KIR full genomic sequences, the distribution of single nucleotide polymorphisms in their coding regions and the length of...
2018/0305743 METHOD OF DETECTING AND IDENTIFYING MICROBIAL SOURCES OF CONTAMINATION IN WATER SYSTEMS
The present invention relates to a method of detecting contaminants of microbial origin in a water distribution system and, more particularly, to a method of...
2018/0305742 USE OF ESTROGENIC COMPOUNDS TO MANIPULATE THE BACTERIAL COMPOSITION OF VAGINAL COMMUNITIES
Disclosed herein are embodiments of a method for using estrogenic compounds to manipulate the bacterial composition of vaginal communities of female subjects....
2018/0305741 METHOD FOR ASSESSING JUICE/CIDER QUALITY AND/OR SAFETY
A novel method for isolating DNA from juices and ciders is described. This method is low cost and yield large quantities of highly purified DNA even though one...
2018/0305740 BEAD BEATING TUBE AND METHOD FOR EXTRACTING DEOXYRIBONUCLEIC ACID AND/OR RIBONUCLEIC ACID FROM MICROORGANISMS
The present disclosure provides improved methods for bead beating and a bead beating system useful therefor. The bead beating system comprises a sample tube,...
2018/0305739 RNA AMPLIFICATION METHODS
Methods of detecting and amplifying short RNAs are provided.
2018/0305738 METHODS OF ATTACHING ADAPTERS TO SAMPLE NUCLEIC ACIDS
Methods of preparing double-stranded nucleic acids with single-stranded overhangs for amplification and sequencing are disclosed. Contacting a blunt-ended...
2018/0305737 Method for Fragmenting a Nucleic Acid for Sequencing
Providing herein, among other things, is a method for preparing a nucleic acid for sequencing. In some embodiments, the method comprises a) amplifying a...
2018/0305736 METHOD FOR EXTRACTING SUBSTANCE FROM FECES SAMPLE
A method for extracting substances from a fecal sample using mass spectrometry or nuclear magnetic resonance spectrometry, and metagenomic analysis using a...
2018/0305735 A METHOD OF INACTIVATING MICROBES BY CITRACONIC ANHYDRIDE
The present invention provides inactivated microbes, methods of preparing and using the same, as well as compositions and kits containing the same. The...
2018/0305734 BLOOD GLUCOSE MEASUREMENT REAGENT, SENSOR CHIP, AND BLOOD GLUCOSE METER SET
A blood glucose measurement reagent includes: an enzyme having glucose as a substrate; a mediator; a chromogenic indicator; and an aromatic hydrocarbon having...
2018/0305733 CAPACITOR FOR DETECTING VIABLE MICROORGANISMS
This invention relates to a capacitor comprising two electrical conductors separated by a dielectric, the dielectric comprising microorganisms. The dielectric...
2018/0305732 KIT AND DISCS FOR USE IN DISC DIFFUSION ANTIBIOTIC SENSITIVITY TESTING
The present invention provides methods and kits for performing microbial sensitivity tests. Specifically, the invention relates to methods for identifying the...
2018/0305731 CONSERVED CHAPERONE DOMAIN FOR TYPE VI SECRETION SYSTEM
The present invention provides a method for identifying a T6SS effector as well as the corresponding T6SS effector immunity protein. The present invention also...
2018/0305730 ASSAY FOR THE COMPREHENSIVE IDENTIFICATION OF ANTIBIOTIC SENSITIVITY
Disclosed herein are methods determining susceptibility of bacteria in a sample from a subject suspected of having an infection to a plurality of antibiotics...
2018/0305729 APPARATUS AND METHOD FOR DETERMINING THE BACTERIAL CHARGE IN A LIQUID OR SEMI-LIQUID PRODUCT
A method for determining the bacterial charge in a liquid or semi-liquid product, including: preparing a quantity of liquid or semi-liquid product to be...
2018/0305728 NOVEL GENE REGULATING VIRULENCE OF CRYPTOCOCCUS NEOFORMANS, AND USE THEREOF
The present invention relates to a novel gene regulating the virulence of Cryptococcus neoformans, and a use thereof. According to the present invention,...
2018/0305727 ENZYMATIC CIRCUITS FOR MOLECULAR SENSORS
In various embodiments a molecular circuit is disclosed. The circuit comprises a negative electrode, a positive electrode spaced apart from the negative...
2018/0305726 METHOD FOR SELECTIVELY PRODUCING GINSENOSIDE F2, COMPOUND Mc OR COMPOUND O FROM SAPONINS OF GINSENG BY...
The present invention relates to a method for selectively producing ginsenoside F2, compound Mc or compound O, which is originally present in ginseng in a...
2018/0305725 Sialylated Glycoproteins
Glycoproteins having particular sialylation patterns, and methods of making and using such glycoproteins, are described.
2018/0305724 PRODUCTION OF HUMAN MILK OLIGOSACCHARIDES IN MICROBIAL HOSTS WITH ENGINEERED IMPORT / EXPORT
The present invention relates to methods for the production of oligosaccharides in genetically modified bacterial host cells, as well as to the genetically...
2018/0305723 METHODS FOR OBTAINING A GENETICALLY MODIFIED PLANT OR MICROBE AND FOR INCREASING OIL YIELD
Methods are provided for obtaining a genetically modified plant, wherein the plant exhibits an increased oil yield relative to a corresponding control plant...
2018/0305722 MICROORGANISM HAVING PHA SYNTHASE-CODING GENES AND METHOD FOR PRODUCING PHA USING SAME
An object of the invention is to improve the crystallization speed of a PHA copolymer which is to be slowly crystallized, and improve the melt workability and...
2018/0305721 Biocatalytic Synthesis of Strained Carbocycles
Provided herein are methods for producing products containing strained carbocycles, such as cyclopropene moieties and/or bicyclobutane moieties. The methods...
2018/0305720 A METHOD FOR PRODUCING A BIOPRODUCT SELECTED FROM ACETONE, ISOPROPANOL AND COMBINATIONS THEREOF
Methods for producing a bioproduct selected from acetone, isopropanol and a combination thereof with a microorganism in a fermentor are disclosed. The methods...
2018/0305719 Vectors For Integration Of DNA Into Genomes And Methods For Altering Gene Expression And Interrogating Gene...
The present disclosure provides vectors and methods for rapid and efficient integration of DNA at target sites in genomes with high efficiency. The present...
2018/0305718 SITE-SPECIFIC DNA MODIFICATION USING A DONOR DNA REPAIR TEMPLATE HAVING TANDEM REPEAT SEQUENCES
A method of site-specific modification of an endogenous target DNA of a eukaryotic cell is provided. The method includes contacting the endogenous target DNA...
2018/0305717 BACULOVIRUS SYSTEM FOR THE EXPRESSION OF A GENE THERAPY VECTOR
The invention relates to a recombinant baculoviral genome useful for the production of viral vectors for gene therapy, allowing said production from a single...
2018/0305716 METHODS AND COMPOSITIONS FOR THE ACTIVATION OF GAMMA-DELTA T-CELLS
The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular,...
2018/0305715 NUCLEIC ACID MOLECULES CONTAINING SPACERS AND METHODS OF USE THEREOF
The present invention relates nucleic acid molecules and concatemers containing spacer sequences useful for the efficient packaging of viral particles so as to...
2018/0305714 INDUCIBLE MODIFICATION OF A CELL GENOME
The present disclosure is directed, in some embodiments, to compositions and methods for inducible modification of a cell genome.
2018/0305713 PARENTAL RNAI SUPPRESSION OF CHROMATIN REMODELING GENES TO CONTROL COLEOPTERAN PESTS
This disclosure concerns nucleic acid molecules and methods of use thereof for control of hemipteran pests through RNA interference-mediated inhibition of...
2018/0305712 TRANSGENIC PLANT OF THE SPECIES SOLANUM TUBEROSUM WITH RESISTANCE TO PHYTOPHTHORA
The present invention concerns a transgenic plant of the species Solanum tuberosum with a resistance to an oomycete of the genus Phytophthora, transgenic parts...
2018/0305711 WHEAT STEM RUST RESISTANCE GENES AND METHODS OF USE
Compositions and methods and for enhancing the resistance of wheat plants to wheat stem rust caused by Puccinia graminis f. sp. tritici are provided. The...
2018/0305710 VACCINE COMPOSITION FOR CLASSICAL SWINE FEVER FROM PLANT AND MANUFACTURING METHOD THEREOF
A recombinant vector for transforming a plant, a plant transformed with the recombinant vector, a plant-made classical swine fever virus antigen pmE2 protein...
2018/0305709 USE OF HETEROLOGOUS EXPRESSED POLYKETIDE SYNTHASE AND SMALL MOLECULE FOLDASES TO MAKE AROMATIC AND CYCLIC COMPOUNDS
A method for producing individual or libraries of tri- to pentadecaketide-derived aromatic compounds of interest by heterologous expression of polyketide...
2018/0305708 Polypeptide for Genome Shuffling in Plants, and Use Therefor
Provided is a genome shuffling technology suited to creating a useful next-generation plant body. Genome shuffling is performed using a polypeptide comprising a...
2018/0305707 GOS2 REGULATORY ELEMENTS AND USE THEREOF
The disclosure relates to gene expression regulatory sequences from Sorghum and Setaria, specifically to the regulatory regions of GOS2 gene and fragments...
2018/0305706 METHODS FOR PRODUCING A COMPLEX TRANSGENIC TRAIT LOCUS
Methods for producing in a plant a complex transgenic trait locus comprising at least two altered target sequences in a genomic region of interest are...
2018/0305705 CONSTRUCTS FOR GENE EXPRESSION ANALYSIS
The present invention relates generally to constructs and their use in gene expression or gene regulation assays. More particularly, the present invention...
2018/0305704 CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and...
2018/0305702 Listeria-Based Immunogenic Compositions And Methods Of Use Thereof in Cancer Prevention And Treatment
Disclosed herein are recombinant Listeria strains comprising nucleotides encoding two or more heterologous antigens each fused to a truncated LLO, an...
2018/0305701 TARGETING MINIVECTORS TO SPECIFIC TISSUE USING SHAPE
Minivectors having defined, non-transient shapes as determined by sequence are provided, along with uses in the targeting delivery of such minivectors to...
2018/0305700 CLEAVABLE FUSION TAG FOR PROTEIN OVEREXPRESSION AND PURIFICATION
Provided are compositions and methods for enhancing recombinant protein production. The compositions and methods involve use of Ribose Binding Protein (RBP) as...
2018/0305699 HEAT-INDUCIBLE SELF-ASSEMBLING PROTEIN DOMAINS
A heat-inducible self-assembling fusion protein that includes a self-assembly domain and a target protein, wherein the self-assembly domain remains folded...
2018/0305698 PHARMACEUTICAL COMPOSITION FOR METABOLIC DISEASE COMPRISING EXPRESSION OR ACTIVITY INHIBITOR OF MKRN1 AS AN...
A pharmaceutical composition for preventing and treating metabolic diseases, which includes an MKRN1 expression or activity inhibitor as an active ingredient,...
2018/0305697 COMPOSITIONS AND METHODS FOR ENHANCING CRISPR ACTIVITY BY POLQ INHIBITION
Provided are approaches to improving CRISPR-based DNA editing by performing the editing in cells in which pol .THETA. ("POLQ") enzyme and/or its function is...
2018/0305696 METHODS AND COMPOSITIONS FOR PREVENTING ISCHEMIA REPERFUSION INJURY IN ORGANS
The invention, in some embodiments, relates to compounds and methods for the prevention of ischemia reperfusion injury (IRI) in organs, and in particular to...
2018/0305695 DNA APTAMER THAT BINDS TO vWF
The purpose of the present invention is to provide an aptamer for vWF, which is superior in a binding ability, a dissociation rate, and/or stability to the...
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