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Patent # Description
2019/0167825 Devices Using Flexible Light Emitting Layer for Creating Disinfecting Illuminated Surface, and Related Method
A light emitting device which inactivates microorganisms is disclosed. The light emitting device may include a flexible light emitting layer emitting a light;...
2019/0167824 STERILIZATION TRAY
A sterilization tray is disclosed herein. A medical instrument, such as an endoscope, may be placed into the sterilization tray, and the sterilization tray...
2019/0167823 METHOD FOR TREATING SOLUTION CONTAMINATED WITH PORCINE CIRCOVIRUSES
The present invention provides a method for treating a solution contaminated with porcine circovirus, comprising the steps of: adjusting a pH of a solution...
2019/0167822 NON-IODINATED RADIOLABELED RADIOPAQUE MICROBEADS WITH MRI CONTRAST FOR RADIOEMBOLIZATION
The invention discloses non-iodinated radiopaque microbeads that may be used in image guided embolization in a subject ailing with tumor. The non-iodinated...
2019/0167821 PROBES FOR IMAGING HUNTINGTIN PROTEIN
Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use. ##STR00001##
2019/0167820 NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT
The present invention relates to an aryl ethene derivative, for inhibiting an estrogen-related receptor gamma (ERR.gamma.) activity, a prodrug of same, a...
2019/0167819 CONTRAST AGENTS
The present invention relates to new class of functionalized polyazamacrocycles including at least one phosphonic or phosphinic group linked to a nitrogen atom...
2019/0167818 FLUORESCENT SOLID LIPID NANOPARTICLES COMPOSITION AND PREPARATION THEREOF
The present invention discloses a solid lipid nanoparticle (SLN) comprising: a) a solid lipid core comprising at least a glyceride and/or at least a fatty add;...
2019/0167817 TREATING METASTATIC CANCER AND MODEL SYSTEMS FOR METASTATIC DISEASE
The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic...
2019/0167816 METHODS FOR PREVENTING OR TREATING FIBROTIC DISEASES
The present invention provides methods for preventing or treating a fibrotic disease in a subject. In some embodiments, the fibrotic disease is fatty liver...
2019/0167815 METHODS AND COMPOSITIONS FOR THE TREATMENT OF RARE DISEASES
The present disclosure is in the field of modulation of genes involved in rare diseases including for diagnostics and therapeutics for rare diseases such as...
2019/0167814 Treatment And/Or Prevention Of DNA-Triplet Repeat Diseases Or Disorders
The present invention refers to the field of DNA repair and to compositions, kits and methods for the treatment and/or prevention of DNA-triplet repeat...
2019/0167813 COMPOSITIONS AND METHODS OF REPLICATION DEFICIENT ADENOVIRAL VECTORS FOR VACCINE APPLICATIONS
The invention includes compositions and methods of generating a chimpanzee-derived adenovirus AdC6 or AdC7 vector vaccine comprising a deletion of E1, a...
2019/0167812 NUCLEIC ACID CONDENSING PEPTIDE, NUCLEIC ACID CONDENSING PEPTIDE SET, NUCLEIC ACID DELIVERY CARRIER, NUCLEIC...
According to one embodiment, a nucleic acid condensing peptide includes one terminal having a first sequence RRRRRR and another terminal having a second...
2019/0167811 LIPID COMPOSITIONS AND THEIR USES FOR INTRATUMORAL POLYNUCLEOTIDE DELIVERY
The present application provides a composition comprising (1) a lipid composition comprising an ionizable amino lipid and a quaternary amine compound and (2) a...
2019/0167810 EXOSOMES COMPRISING THERAPEUTIC POLYPEPTIDES
The present invention pertains to an inventive release mechanism for extracellular vesicle (EV)-mediated intracellular and intramembrane delivery of...
2019/0167809 METHODS OF TREATING A SUBJECT WITH mRNA ENCODING COAGULATION FACTOR VIII (F8)
The present invention relates to a complexed RNA, comprising at least one RNA complexed with one or more oligopeptides, wherein the oligopeptide has a length...
2019/0167808 METHODS OF TREATING PHENYLKETONURIA WITH MRNA ENCODING PHENYLALANINE HYDROXYLASE (PAH)
The present invention relates to a complexed RNA, comprising at least one RNA complexed with one or more oligopeptides, wherein the oligopeptide has a length...
2019/0167807 Adipose Tissue-Targeting Polypeptide-Verbascoside-Nanogold Particle Derivative, Preparation Method and...
Embodiments of the present disclosure provides a method of preparing an adipose tissue-targeting polypeptide-verbascoside-nanogold particle derivative,...
2019/0167806 DRUG CONJUGATES WITH SELF-STABILIZING LINKERS HAVING IMPROVED PHYSIOCHEMICAL PROPERTIES
Compounds and compositions are disclosed in which a Drug Unit is linked to a targeting Ligand Unit through a self-stabilizing Linker Unit from which a drug...
2019/0167805 Immunoconjugates with an Intracellularly-Cleavable Linkage
The present invention relates to therapeutic conjugates with improved ability to target various diseased cells containing a targeting moiety (such as an...
2019/0167804 GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF
Provided herein are glucocorticoid receptor agonist immunoconjugates, glucocorticoid receptor agonists, and methods of using the same.
2019/0167803 TLR9 TARGETED CYTOTOXIC AGENTS
Disclosed are compositions and methods for targeted treatment of TLR9-expressing cancers. In particular, molecules containing a TLR9 targeting ligand, such as...
2019/0167802 SELF-EMULSIFYING COMPOSITION OF OMEGA3 FATTY ACID
A self-emulsifying composition contains: 70 to 90% by weight of at least one compound selected from the group consisting of .omega.3 polyunsaturated fatty...
2019/0167801 Injectable, Non-Aqueous Suspension with High Concentration of Therapeutic Agent
An injectable, nonaqueous suspension including at least one therapeutic agent suspended in a single component vehicle. The single component vehicle is a single...
2019/0167800 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS
The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular,...
2019/0167799 ETHER TYPE GLYCEROPHOSPHOLIPID-CONTAINING COMPOSITION AND METHOD FOR PRODUCING THE SAME
To provide an ether-type glycerophospholipid-containing composition that has excellent heat stability and also has oxidation stability and storage stability....
2019/0167798 MEMBRANE FOR STICKING TO LIVING ORGANISM, AND METHOD FOR PRODUCING SAME
A cellulose membrane according to an embodiment of the present disclosure is a self-supporting cellulose membrane having a thickness of between 20 nm and 1300...
2019/0167797 STABILIZED FACTOR IX FORMULATIONS CONTAINING TREHALOSE
Methods of preparing lyophilized preparations of Factor IX which preserve more than 90% of the calcium binding property of Factor IX are disclosed. Factor IX...
2019/0167796 METHODS OF TREATING OR PREVENTING STENT THROMBOSIS
The present invention is directed to the following: methods of treating or preventing stent thrombosis using pharmaceutical compositions comprising cangrelor...
2019/0167795 CONJUGATED LIPOMERS AND USES THEREOF
The present invention provides inventive conjugated polyethyleneimine (PEI) polymers and conjugated aza-macrocycles (collectively referred to herein as...
2019/0167794 ATROPISOMERS OF HALOGENATED TETRAPHENYLBACTERIOCHLORINS AND CHLORINS AND THEIR USE IN PHOTODYNAMIC THERAPY
This invention relates to atroipsomers of reduced tetraphenylporphyrin derivatives with halogen atoms (F, Cl, Br) in the ortho positions of the phenyl groups,...
2019/0167793 NEAR-IR LIGHT-CLEAVABLE CONJUGATES AND CONJUGATE PRECURSORS
Embodiments of near-infrared light-cleavable heptamethine cyanine-based conjugates, particularly targeting agent-drug conjugates, according to Formula I and...
2019/0167792 Anaerobic Blood Storage and Pathogen Inactivation Method
A method for reducing hemolysis and microparticle formation during storage of pathogen reduced blood. Oxygen reduced blood compositions comprising SAGM and...
2019/0167791 IMMUNOTHERAPEUTIC USES OF EX VIVO GENERATED FOXP3+ REGULATORY T CELLS
The present invention relates to therapeutic uses of ex vivo generated Foxp3+ regulatory T cells. The inventors showed the presence of Foxp3+ expressing T...
2019/0167790 ABT-165 IN COMBINATION WITH FOLINIC ACID, 5-FLUOROURACIL, AND IRINOTECAN FOR THE TREATMENT OF CANCERS
This invention pertains to a method for the treatment of cancer in a subject comprising administering to the subject an effective amount of ABT-165 in...
2019/0167789 IMMUNOTHERAPY TREATMENTS AND COMPOSITIONS
The present invention relates to compositions and kits comprising a peptide that activate the immune response and methods of using the composition for...
2019/0167788 Composition and Method for Treating Cancer
Pharmaceutical compositions useful as vaccines are described containing a purified surface or excreted protein qualitatively or quantitatively associated with...
2019/0167787 Methods and Compositions for Inhibiting Akt3
Compounds and compositions for selectively inhibiting Akt3 are provided. Methods of using the compounds are also provided. Because Akt3 modulates the...
2019/0167785 METHODS OF ORAL IMMUNOTHERAPY
The present disclosure relates to improved oral immunotherapy methods for treating food allergies, and particularly peanut allergy. Biomarkers, such as a level...
2019/0167784 RECOMBINANT VIRUS WITH DIMINISHED LATENCY AND METHODS OF USING SAME
The disclosure provides recombinant herpes virus with diminished latency. In embodiments, the recombinant herpes virus comprises a latency gene or transcript...
2019/0167783 VACCINE
The present invention relates, in general, to an HIV-1 vaccine and, in particular, to a B cell lineage-based vaccination protocol.
2019/0167782 VACCINATION IN NEWBORNS AND INFANTS
The present invention relates to vaccines comprising at least one mRNA encoding at least one antigen for use in the treatment of a disease in newborns and/or...
2019/0167781 RECOMBINANT INFLUENZA VIRUSES WITH STABILIZED HA FOR REPLICATION IN EGGS
Modified influenza virus neuraminidases are described herein that improve viral replication, thus improving the yield of vaccine viruses. Expression of such...
2019/0167780 INFLUENZA VIRUS VACCINES
The invention provides a vaccine for protecting a human patient against infection by a human influenza virus strain, wherein the vaccine comprises an antigen...
2019/0167779 Synthetic Antigen Constructs Against Campylobacter Jejuni
The invention relates to immunogenic synthetic constructs capable of inducing an immune response against Campylobacter jejuni (C. jejuni) in a subject...
2019/0167778 IMMUNOMODULATORY MINICELLS AND METHODS OF USE
The present disclosure is related to immunomodulatory bacterial minicells and methods of using the minicells.
2019/0167777 ADJUVANT COMPOSITIONS AND RELATED METHODS
The present disclosure provides for an adjuvant composition that is suited for injectable as well as transdermal administration. The adjuvant composition...
2019/0167776 CAMKK2 INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAME
Provided herein are compositions including a CaMKK2 inhibitor and an anti-cancer therapeutic agent and methods of treating cancer in a subject by administering...
2019/0167775 METHODS AND COMPOSITIONS FOR TREATING CANCER
Provided herein, in some embodiments, are methods and composition for treating cancer in a subject. The methods may include administering to the subject a...
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