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Patent # Description
2019/0167723 SERUM FRACTION OF PLATELET-RICH FIBRIN AS A CELL CULTURE ADDITIVE
A method of preparing an isolated serum fraction of platelet rich fibrin, cell cultures comprising said serum fraction and its use as a cell culture additive....
2019/0167722 TRANSFECTION OF DENDRITIC CELLS AND METHODS THEREFOR
Immunotherapeutic methods and compositions are contemplated where one or more neoepitopes and/or tumor associated antigens are produced in, or delivered to...
2019/0167721 SINGLE-CHAIN ANTIBODY SPECIFICALLY BINDING MG7, HIGHLY GLYCOSYLATED CEA AND USE THEREOF IN DETECTION AND THERAPY
The present invention provides a glycosylated CEA-specific single-chain antibody, and a chimeric antigen receptor (CAR) targeting a glycosylated CEA, which can...
2019/0167720 GENE EDITING FOR IMMUNOLOGICAL DESTRUCTION OF NEOPLASIA
Disclosed are methods, protocols, and compositions of matter useful for induction and/or propagation of antitumor immune responses through gene editing of...
2019/0167719 Blood Plasma and Plasma Fractions as Therapy for Tumor Growth and Progression
The invention relates to treating individuals with cancer by using blood plasma or blood plasma fractions as treatment.
2019/0167718 COMPOSITIONS AND METHODS FOR ACTIVATING ANTIGEN PRESENTING CELLS WITH CHIMERIC POLIOVIRUS
Chimeric poliovirus is capable of activating antigen presenting cells. The activation of the antigen presenting cells may be in vitro, ex vivo, or in vivo. The...
2019/0167717 METHODS FOR TREATING SKIN IRRITATION
The present invention provides a stabilized hypohalous acid solution (or formulation thereof), which may be conveniently packaged for sale, or stored for later...
2019/0167716 Use of Electrolyzed Water for Treatment and Prevention of Common Livestock Diseases and Conditions, Including PRRS
Respiratory symptoms resulting from disease states such as PRRS and Streptococcus infections can be alleviated by administration of electrolyzed water via fog...
2019/0167715 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING PROTEINURIA AND ENDOTHELIAL EROSION
In some embodiments, a system and/or method may inhibit and/or ameliorate proteinuria and related comorbidities in a subject. In some embodiments, proteinuria...
2019/0167714 HYDROGEL COMPOSITIONS AND USES THEREOF
The present application provides compositions configured to be provided in a flowable, liquid form but that are configured to transition to a solid or...
2019/0167713 Medicament for the Treatment of Acute Liver Failure
The present invention relates to a compound for use as a medicament in the treatment or prevention of acute liver failure, which acute liver failure is induced...
2019/0167712 MICRO-RNAS AND COMPOSITIONS COMPRISING SAME FOR THE TREATMENT AND DIAGNOSIS OF SEROTONIN-, ADRENALIN-,...
microRNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing...
2019/0167711 METHODS FOR DIAGNOSIS AND TREATMENT OF ACUTE LYMPHOBLASTIC LEUKEMIA
Provided herein is the use of miR-451 as a biomarker in prognosis of anti-ALL treatment modalities, in early diagnosis of ALL relapse risk, and/or in...
2019/0167710 Methods of Treating Conditions Involving Elevated Inflammatory Response
A method of treating a patient having an elevated inflammatory response, such as an elevated Type I interferon response, is provided. The method can be used to...
2019/0167709 COMPOSITIONS AND METHODS FOR INDUCING APOPTOSIS
In an aspect, the invention relates to compositions, method, and kits for inducing apoptosis. This abstract is intended as a scanning tool for purposes of...
2019/0167708 TUMOR SUPPRESSOR TET1 AND USES THEREOF
The present invention provides a method for assessing the risk of cancer in a subject by detecting elevated methylation level in the genomic sequence of the...
2019/0167707 Cladribine regimen for treating progressive forms of Multiple Sclerosis
Specific oral dosings, specific oral dosage forms, and/or specific oral dose regimens including Cladribine can be effective for the treatment of progressive...
2019/0167706 Solid Pharmaceutical Composition Comprising Amorphous Sofosbuvir
It is provided a solid pharmaceutical composition comprising sofosbuvir, one or more pharmaceutically acceptable excipients and optionally at least one...
2019/0167705 COMPOSITIONS CONTAINING PUFA AND-OR URIDINE AND METHODS OF USE THEREOF
This invention provides methods of enhancing brain development; increasing or enhancing intelligence; increasing or enhancing synthesis and levels of...
2019/0167704 THERAPEUTIC COMBINATIONS COMPRISING ANTI-FOLR1 IMMUNOCONJUGATES
Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-VEGF agents (e.g., bevacizumab), a platinum-based agent, and/or...
2019/0167703 COMPOSITIONS FOR ORAL ADMINISTRATION OF ZOLEDRONIC ACID OR RELATED COMPOUNDS FOR TREATING DISEASE
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
2019/0167702 USE OF DERIVATIVES CONTAINING C-O-P BONDS IN PATIENTS WITH KIDNEY FAILURE
Use of a derivative containing C--O--P bonds in a controlled release form to treat patients with kidney failure. Moreover, it comprises the use of said...
2019/0167701 Methods of Treating Eye Pain With Aminophosphinic Derivatives
The disclosure relates to a method of treating or preventing eye pain in a subject in need thereof. The method includes administering a compound of formula...
2019/0167700 METHOD FOR THE MANAGEMENT OF DYSMENORRHEA AND MENSTRUAL PAIN
The present invention relates to a method for the management of dysmenorrhea involving administration of an estrogenic component which is preferably selected...
2019/0167699 PROSTATE FUNCTION SUPPORT FORMULA
The invention provides unit dosage forms and methods that are effective to improve prostate function. Such unit dosage forms and methods are useful to decrease...
2019/0167698 Methods of Treating Certain Depressive Disorders and Delirium Tremens
The disclosure provides a method of treating a patient having postpartum depression, premenstrual dysphoric disorder, menopausal depression, or delirium...
2019/0167697 Methods of Reducing Mammographic Breast Density and/or Breast Cancer Risk
The present disclosure is directed to generally methods and/or compositions for treating mammographic breast density and/or breast stiffness in a patient in...
2019/0167696 METHOD OF TREATING HYPERTENSION
Disclosed herein are methods of treating pulmonary hypertension, including pulmonary arterial hypertension, by administering to a patient in need thereof an...
2019/0167695 COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS
Provided herein are compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy. In some embodiments, the compositions...
2019/0167694 NEW THERAPEUTICS USES
New uses of an EGFR inhibitor are disclosed. Methods of treatment using the EGFR inhibitor are also disclosed.
2019/0167693 METHOD OF TREATING PATIENTS COADMINISTERED A FACTOR Xa INHIBITOR AND VERAPAMIL
The present disclosure in various embodiments teaches methods of treating patients in need of treatment with a Factor Xa inhibitor, and who are also...
2019/0167692 SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)- IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE AND...
The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor ...
2019/0167691 TRANSIENT PROTECTION OF HEMATOPOIETIC STEM AND PROGENITOR CELLS AGAINST IONIZING RADIATION
This invention is in the area of improved compounds and methods for transiently protecting healthy cells, and in particular hematopoietic stem and progenitor...
2019/0167690 Immuno-Gene Combination Therapy
"In situ vaccination" using immuno-gene therapy has the ability to induce polyclonal anti-tumor responses directed by the patient's immune system. Patients...
2019/0167689 MODULATION OF THE NITRIC OXIDE SYNTHASE PATHWAY FOR ORAL HEALTH
Pharmaceutical compositions and methods of treatment or prevention of diseases and conditions associated with or characterized by at least one of xerostomia...
2019/0167688 POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4
Disclosed herein are tricyclic compounds, including thieno[2,3-d:4,5-d']dipyrimidin-4-amine and pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-8-amine compounds,...
2019/0167687 METHODS FOR THE TREATMENT OF HER2 AMPLIFIED CANCER
Described herein are methods and compositions for treating HER2-amplified cancer. The methods include administering to an individual in need thereof ibrutinib.
2019/0167686 SMALL MOLECULE INHIBITORS OF EGFR AND PI3K
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or...
2019/0167685 SELECTIVE CALCIUM CHANNEL ANTAGONISTS
The present invention relates to compositions and methods for the treatment and/or prevention of neurodegenerative disorders, e.g., Parkinson's disease (PD)....
2019/0167684 COMPOSITIONS AND METHODS FOR TREATING HCV
This disclosure is directed to pharmaceutical compositions that comprise two or more therapeutic agents that, inter alia, are useful for inhibiting hepatitis C...
2019/0167683 PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING OR PREVENTING A RESPIRATORY SYNCYTIAL VIRUS INFECTION
Pyrimidine derivatives of formula (I) wherein: Z is a direct bond or --(CH.sub.2).sub.n-- wherein n is 1 or 2; one of X and Y is N, CH or CF, and the other of...
2019/0167682 PYRIDINE SULFONAMIDES
The present invention provides compounds of Formula (I), as defined in the specification, or pharmaceutically acceptable salts thereof, that are inhibitors of...
2019/0167681 SULFONYL PYRIDYL TRP INHIBITORS
The invention provides compounds of formula I: ##STR00001## and pharmaceutically acceptable salts thereof where R.sup.1 is a substituted or unsubstituted phenyl...
2019/0167680 Inhibition of JAK-STAT Signaling Inhibits Formation of Neutrophil Extracellular Traps (NETs)
The methods described herein include methods for the treatment of subjects who have Clonal Hematopoiesis of Indeterminate Potential (CHIP) or a...
2019/0167679 sGC STIMULATORS
Compounds of Formulae I' and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds...
2019/0167678 SOLID FORMS OF 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRI- ...
Provided herein are formulations, processes, solid forms and methods of use relating to ...
2019/0167677 Method Of Treating Metabolic Disorders And Depression With Dopamine Receptor Agonists
This invention relates to methods and formulations for treating metabolic disorders and depression. In some embodiments, the methods comprise administering a...
2019/0167676 METHODS FOR IMPROVING RESISTANCE TO SKELETAL MUSCLE FATIGUE
Provided are compounds, compositions and methods for improving resistance to skeletal muscle fatigue comprising administering an effective amount of a skeletal...
2019/0167675 METHODS AND COMPOSITIONS FOR APPETITE CONTROL AND WEIGHT MANAGEMENT
The present invention provides methods and compositions for modulation of appetite, or for treatment of an appetite disorder or a metabolic disorder such as...
2019/0167674 VIGOR ENHANCEMENT VIA ADMINISTRATION OF PYRIMIDINE DERIVATIVES
Disclosed herein are methods for increasing the overall vigor of a subject, and/or vigor of target tissues of a subject. Exemplified herein is the utilization...
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