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Patent # Description
2019/0167673 ARIPIPRAZOLE FORMULATIONS HAVING INCREASED INJECTION SPEEDS
The present invention relates to pharmaceutical compositions comprising a compound of Formula (I) that are useful for the intramuscular delivery of ...
2019/0167672 PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS
Provided is a superior, novel heterocyclic compound with improved solubility in oil such as sesame oil and benzyl benzoate, which has a broader treatment...
2019/0167671 OXABICYCLOHEPTANES AND OXABICYCLOHEPTENES FOR THE TREATMENT OF DIABETES
A method of increasing the insulin sensitivity of a mammalian cell by contacting the cell with a protein phosphatase 2A (PP2A) inhibitor having the structure...
2019/0167670 METHODS OF TREATING OR PREVENTING ZIKA VIRUS INFECTION
This document relates to methods and materials for treating a mammal having a Zika virus (ZIKV) infection. For example, a composition including one or more...
2019/0167669 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL
The present methods treat neurofibromatosis by a administering to a subject perillyl alcohol or iso-perillyl alcohol. The present methods also treat...
2019/0167668 Analgesic therapeutic and method, 1-(3-4(((1R,3S,5S)-adamantan-1-yl)(phenyl)methyl)propyl)-4-methylpiperazi- ...
A method for the treatment and/or prevention of pain which comprises administering to a subject in need of such treatment a therapeutically effective amount...
2019/0167667 Liquid Formulations of Salts of 1-[2-(2,4-Dimethylphenylsulfanyl)Phenyl]-Piperazine
Liquid formulations of lactic acid addition salts of 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine are provided.
2019/0167666 METHODS FOR TREATING DEPRESSIVE SYMPTOMS
The present application relates methods for treating a depressive symptom comprising administering an effective amount of a .mu. opioid receptor agonist or a...
2019/0167665 MORPHINE FORMULATIONS
Provided herein, generally, are pharmaceutical formulations, e.g., injectable pharmaceutical formulations with improved stability, comprising morphine sulfate...
2019/0167664 Polymorphic Forms of Naltrexone
This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and...
2019/0167663 Abuse Resistant Pharmaceutical Compositions
The present invention relates to a composition comprising pharmaceutical active ingredients which are susceptible to, or have potential for, abuse. The...
2019/0167662 TAMPER-RESISTANT PHARMACEUTICAL COMPOSITIONS OF OPIOIDS AND OTHER DRUGS
Tamper-resistant pharmaceutical compositions have been developed to reduce the likelihood of improper administration of drugs, especially drugs such as...
2019/0167661 Nanoliposomal Irinotecan for Use in Treating Small Cell Lung Cancer
Novel therapies for the treatment of small cell lung cancer (SCLC) include the administration of an antineoplastic therapy consisting of liposomal irinotecan...
2019/0167660 PPAR-gamma AGONIST FOR TREATMENT OF BONE DISORDERS
Methods of treatment of bone disorders, including osteoporosis or its symptoms, with PPAR.UPSILON. agonists, and in particular, the compound of formula (I)...
2019/0167659 CCR6 COMPOUNDS
Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6: ##STR00001##
2019/0167657 NUTRITIONAL SUPPLEMENT FOR IMPROVING SEXUAL HEALTH IN MEN AND WOMEN
The invention provides compositions and methods that are effective to improve NO production in vivo and/or to increase NO levels in blood. Such compositions...
2019/0167656 NUTRITIONAL SUPPLEMENT FOR INCREASING COGNITIVE FUNCTIONS
The invention provides compositions and methods that are effective to improve NO production in vivo and/or to increase NO levels in blood. Such compositions...
2019/0167655 Transdermal Administration Of Fentanyl And Analogs Thereof
A method and a non-rate controlled, monolithic, subsaturated patch for transdermally administering fentanyl and analogs thereof, for analgetic purposes, to a...
2019/0167654 DOSE-DUMPING RESISTANT CONTROLLED RELEASE DOSAGE FORM
The present invention provides a simple and improved dosage form that provides a controlled release of methylphenidate contained in the core thereof. The...
2019/0167653 MATERIALS AND METHODS FOR DIAGNOSIS, PREVENTION AND/OR TREATMENT OF STRESS DISORDERS AND CONDITIONS ASSOCIATED...
The subject invention concerns materials and methods for treating and/or preventing diseases associated with accumulation of A.beta. peptide in neural tissue....
2019/0167652 PHARMACEUTICAL COMBINATION COMPRISING LSZ102 AND ALPELISIB
The present invention relates to a pharmaceutical combination comprising LSZ102 and alpelisib; pharmaceutical compositions comprising the same; and methods of...
2019/0167651 HETEROARYL SULFONAMIDES AND CCR2/CCR9
Compounds are provided that act as potent antagonists of the CCR2 receptor. Animal testing demonstrates that these compounds are useful for treating...
2019/0167650 METHODS OF TREATING PANCREATIC CANCER
The present disclosure describes methods of treating pancreatic cancer and limiting over-expression of oncogenes, activating tumor suppressor genes or...
2019/0167649 TOPICAL RAPAMYCIN THERAPY
A topical composition containing rapamycin and an alcohol-free carrier is used to deliver rapamycin to skin cells while preventing systemic absorption,...
2019/0167648 GLUTAMINASE INHIBITORS
A compound, or a pharmaceutically acceptable salt thereof, having a structure of: ##STR00001## wherein A is a ring; Y.sup.1 and Y.sup.2 are each independently...
2019/0167647 PHARMACEUTICAL COMPOSITION FOR STROKE TREATMENT BASED ON AMPK INHIBITION
A method for treating stroke in a subject includes administering to the subject a composition that includes a compound having a structure represented by...
2019/0167646 TREATMENT OF HEPATITIS DELTA VIRUS INFECTION
Methods of reducing hepatitis delta virus (HDV) viral loads in a patient are provided. In some embodiments, the method comprises treating the patient with...
2019/0167645 THERAPEUTIC AGENT FOR DYSLIPIDEMIA
The present invention addresses the problem of providing a pharmaceutical combination composition and drug combinations for the prevention and/or treatment of...
2019/0167644 AGENT FOR REDUCING VISCERAL FAT WEIGHT
An FGF21 production promoting agent containing, as an active ingredient, a compound represented by the following formula (1): ##STR00001## wherein each of...
2019/0167643 FORMULATIONS OF DEFERASIROX AND METHODS OF MAKING THE SAME
The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the...
2019/0167642 COMPOUNDS AND METHODS FOR TREATING AN EPILEPTIC DISORDER
Provided, inter alia, are methods for treating an epilepsy disorder using clemizole, a clemizole analog, or pharmaceutical salts thereof.
2019/0167641 USE OF VCP INHIBITOR AND ONCOLYTIC VIRUS IN THE PREPARATION OF AN ANTI-TUMOR DRUG
The present invention belongs to the field of biomedicine and relates to use of VCP (valosin-containing protein, VCP) inhibitor and oncolytic virus in the...
2019/0167640 METHODS FOR TREATMENT OF MUSCULAR DYSTROPHIES
The present invention relates to, inter alia, treatment of muscle dystrophy (e.g., Duchenne Muscular Dystrophy), for example, using a composition, e.g., a...
2019/0167639 SYNERGISTIC PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF SQUAMOUS CELL CARCINOMA OF HEAD AND NECK
The present invention relates to a pharmaceutical combination for use in the treatment of squamous cell carcinoma, comprising a CDK inhibitor selected from the...
2019/0167638 USE OF PRODRUGS OF FUMARATES IN TREATING HEART FAILURE DISEASES
Methods and pharmaceutical compositions comprising one or more prodrugs (e.g., aminoalkyl prodrugs) of monomethyl fumarate (MMF) thereof are provided herein...
2019/0167637 NOVEL INHIBITORS OF BACTERIAL GROWTH
New antimicrobials targeting L,D-transpeptidases, non-classical cysteine peptidases, have been developed and their unique chemical structures identified....
2019/0167636 METHODS FOR TREATING PULMONARY EMPHYSEMA USING SUBSTITUTED 2-AZA-BICYCLO[2.2.1]HEPTANE-3-CARBOXYLIC ACID ...
This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 ##STR00001## and their use as inhibitors of...
2019/0167635 NONRACEMIC MIXTURES AND USES THEREOF
Provided are compositions comprising unequal mixtures of (R)-amisulpride and (S)-amisulpride, or pharmaceutically acceptable salts thereof, where the amount of...
2019/0167634 METHOD OF TREATING CANCER WITH COMBINATIONS OF HISTONE DEACETYLASE INHIBITORS (HDAC1) SUBSTANCES
A method for treating cancer is described using combination therapies comprising the use of hyperbaric oxygen with histone deacetylase inhibitors, with and...
2019/0167633 COMBINATION THERAPY FOR EFFECTING WEIGHT LOSS AND TREATING OBESITY
The present invention features a novel therapy for effecting weight loss which involves treating a subject with a sympathomimetic agent (e.g., phentermine or a...
2019/0167632 METHODS OF TREATING AND PREVENTING/REDUCING THE LIKELIHOOD OF MESIAL TEMPORAL LOBE EPILEPSY (TLE)
The invention provides methods of treatment that prevent the onset of Mesial temporal lobe epilepsy (TLE) in a subject, or which reduce the severity of TLE in...
2019/0167631 Taxane- and Taxoid-Protein Compositions
Compositions comprising a taxane or taxoid, such as paclitaxel, and a protein, such as albumin or a metal-transferrin, such as gallium-transferrin, can be...
2019/0167630 EFFLUX INHIBITOR COMPOSITIONS AND METHODS OF TREATMENT USING THE SAME
The present invention relates to efflux inhibitor compositions and methods of using these agents for treating conditions where the activity of efflux...
2019/0167629 COMBINATION THERAPY METHODS FOR TREATING PROLIFERATIVE DISEASES
The present invention provides combination therapy methods of treating a proliferative disease (such as cancer) comprising a first therapy comprising...
2019/0167628 METHODS FOR TREATING SARCOMA
Molecular markers of response to various chemotherapies were measured in tumor samples of 5 sarcoma subtypes to identify effective treatment regimens based on...
2019/0167627 AZELAIC ACID ESTERS IN THE TREATMENT OF INSULIN RESISTANCE
A method of treating insulin resistance includes administering to a subject a pharmaceutical composition comprising diethyl azelate. For example, a method of...
2019/0167626 RETINAL DERIVATIVES AND METHODS FOR THE USE THEREOF FOR THE TREATMENT OF VISUAL DISORDERS
Compositions of and methods for using synthetic retinal derivatives as retinoid replacements and opsin agonists are provided.
2019/0167625 METHODS AND COMPOSITIONS FOR REDUCING OCULAR DISCOMFORT
The invention relates to compositions and devices which include an osmolytic agent, in particular a betaine or carnitine compound, for reducing ocular...
2019/0167624 PREVENTION AND/OR TREATMENT OF NEURODEGENERATIVE DISEASE
A method for the prevention and/or treatment of dementia in a human subject; the method comprising the step of administering an effective amount of a...
2019/0167623 IMMUNOTHERAPEUTIC AGENT
Compounds for use in the treatment of sepsis and/or the prevention or treatment of post-sepsis syndrome.
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