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Patent # Description
US-5,432,191 Allosteric hemoglobin modifiers to decrease oxygen affinity in blood
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The compounds are capable of acting on...
US-5,432,190 Pharmaceutical compositions containing triazoles and method of treating estrogen-dependent diseases
Azole derivatives (including stereoisomers and pharmaceutically acceptable salts) of the formula: ##STR1## wherein R.sub.1 and R.sub.2 each are H or C.sub.1...
US-5,432,189 Bis-aryl amide and urea antagonists of platelet activating factor
Bis-aryl amide and urea compounds of the general formula: ##STR1## wherein X is a divalent amide or urea substituent and Y is a nitrogen containing...
US-5,432,188 4-heteroaryl- and 4-aryl-1,4-dihydropyridine compounds
There are provided novel 1,4-dihydropyridine compounds, compositions containing them and methods of using them to treat congestive heart failure.
US-5,432,187 Benzimidazole anthelmintic in the treatment of microsporidial infections
The present inventions relates to the use of certain benzimidazole compounds in the treatment of diseases caused by microsporidia organisms, in particular the...
US-5,432,186 Cyclic amino acid derivatives
Disclosed are the compounds of formula I ##STR1## wherein R represents hydrogen, lower alkyl, carbocyclic or heterocyclic aryl-lower alkyl or...
US-5,432,185 Haemorheological use of N-alkylated 1,4-dihydropyridine-dicarboxylic acid esters, and some new compounds
Improving circulation, with minimal effect on blood pressure, using N-alkylated 1,4-dihydropyridines of the formula ##STR1## in which R.sup.1 represents...
US-5,432,184 Microbial inhibiting compositions and their use
A biocidal composition and method for inhibiting and controlling the growth of the fungus, Trichoderma viride, are disclosed. The composition comprises an...
US-5,432,183 Use of rapamycin prodrugs as immunosuppressant agents
The use of rapamycin prodrugs of formula I as immunosuppressant agents, intermediates formed in the preparation of its prodrugs as well as the prodrugs...
US-5,432,182 Compounds substituted quinoline derivatives
Substituted 4-aminoquinazoline derivatives which are inhibitors of gastric acid secretion. A compound of the invention are the salts of strong acids of...
US-5,432,181 Substituted heteroaryl analogs of 4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidines useful as ...
The present invention is novel compounds which are 4,6-di-tertiary-butyl-5-hydroxy-1,3-pyrimidine substituted 1,2,4- and 1,3,4-thiadiazoles and oxadiazoles, and...
US-5,432,179 Piperazine derivatives and pharmaceuticals containing the same
A piperazine derivative represented by the following formula: ##STR1## or a pharmaceutically acceptable salt thereof. The compound according to the present...
US-5,432,178 Amidinophenol derivatives
Amidinophenol derivatives of the formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are (i) H, (ii) C1-4 alkyl, (iii) C1-4 alkoxy, (iv) C2-5 acyl, (v)...
US-5,432,177 Pyrrolo-pyridine derivatives
A class of pyrrolo[2,3-b]pyridine derivatives, substituted at the 3-position by a substituted piperazinylmethyl moiety, are antagonists of dopamine receptor...
US-5,432,176 Method of retarding the progression of chronic renal failure
Progression of chronic renal failure can be retarded or arrested by administering to humans suffering from such disorder an agent which suppresses the production...
US-5,432,175 Pyridine and pyridine N-oxide derivatives of diaryl methyl piperidines or piperazines, and compositions and...
Pyridine and pyridine N-oxide derivatives of diaryl methyl piperidines or piperazines and pharmaceutically acceptable salts thereof are disclosed, which possess...
US-5,432,174 Treatment of ocular hypertension
A method for the treatment of ocular hypertension which comprises administering, to a subject in need of such treatment, (a) a .beta.-adrenergic blocker at the...
US-5,432,173 1-amidooctahydropyrido[2,1,-C][1,4]oxazine compounds
The invention relates to the compounds of general formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and A are as defined in the...
US-5,432,172 Biological applications of alkaloids derived from the tunicate Eudistoma sp.
Biological applications of synthetic and natural alkaloids derived from the tunicate Eudistoma sp. are disclosed. A method regulating cell growth includes...
US-5,432,171 Water soluble texaphyrin metal complexes for viral deactivation
The present invention involves water soluble hydroxy-substituted texaphyrins retaining lipophilicity, the synthesis of such compounds and their uses. These...
US-5,432,170 Process for the production of semisolid preparations containing micronized active ingredients
A process for the production of semisolid preparations containing micronized active ingredients is described which is characterized in that a mixture of one or...
US-5,432,169 Cyclopentanperhydrophenanthren-17.beta.-(3-furyl)-3-derivatives and pharmaceutical compositions comprising same...
Cyclopentanperhydrophenantren-17.beta.-(3-furyl)-3-derivatives and pharmaceutical compositions containing same for the treatment of cardiovascular disorders such...
US-5,432,168 Method of treatment of hormone-unresponsive metastatic prostate cancer
Prostate cancer particularly hormone-unresponsive metastatic prostate cancer, is treated by cyclophosphamide or other normally substantially inactive agent....
US-5,432,167 Cell proliferation matrix and use thereof
A cell proliferation matrix consisting of an aqueous gel of hyaluronic acid or a pharmaceutically acceptable salt thereof which is free from production-related...
US-5,432,166 Use of 1-(.beta.-D-arabinofuranosyl) -5-propynyluracil for lowering serum cholesterol
The use of 1-(.beta.-D-arabinofuranosyl)-5-propynyluracil or a pharmaceutically acceptable salt or physiologically labile ester thereof for lowering serum...
US-5,432,165 Methods for the treatment of infection caused by Hepatitis B virus (HBV)
The present invention relates to pharmaceutical compositions useful for the treatment of subjects suffering from an infection or disease caused by the hepatitis...
US-5,432,164 C2,N.sup.6 -disubstituted adenosine derivatives
A compound of formula (I), or a pharmaceutically acceptable salt thereof: ##STR1## wherein X is halogen, perhalomethyl, cyano, C.sub.1-6 -alkoxy, C.sub.1-6 ...
US-5,432,163 Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides
Compounds of this invention are derivatives of pentose monosaccharides which exhibit anti-proliferative and anti-inflammatory activity as well as intermediates...
US-5,432,162 Reducing post-prandial fluctuations in plasma concentrations of large neutral amino acids (LNAA)
Methods of reducing post-prandial fluctuations in plasma levels of large, neutral amino acids (LNAA), as well as compositions useful in that method. The foods...
US-5,432,161 Crystalline 2-O-.alpha.-d-glucopyranosyl-L-ascorbic acid, and its preparation and uses
2-O-.alpha.-D-Glucopyranosyl-L-ascrobic acid is crystallizable in its supersaturated solution. Crystalline 2-O-.alpha.-D-glucopyranosyl-L-ascorbic acid is...
US-5,432,160 Nutrient composition
A nutrient composition such as infusions and nutrient preparations, which contains .beta.-alanyl-L-glutamine.
US-5,432,159 N-(.alpha.-substituted-pyridinyl)carbonyl dipeptide antihypertensive agents
Dipeptide derivatives are taught which are of general formula (I) ##STR1## including tautomeric forms thereof, wherein: n is 0 or an integer of from 1 to...
US-5,432,157 Chrysospermins, active peptides from apiocrea chrysosperma having a pharmacological effect and a use thereof
The invention relates to the chrysospermin active peptides of the formula I in which x and y, independently of each other, denote Aib or Iva, which are synthesized by...
US-5,432,156 Therapeutic agent for digestive tract diseases
Therapeutic agents for the digestive tract diseases which comprise glicentin as active ingredients.
US-5,432,155 Conotoxins I
Substantially pure conotoxins are provided which inhibit synaptic transmissions at the neuromuscular junctions and which are useful both in vivo and in assays...
US-5,432,154 Ethers for aromatizing purposes
The invention relates to novel ethers and their use as aroma precursors. The ethers are derived from ionol and related compounds. These aroma precursors do not...
US-5,432,153 Gelling compositions useful for oil field applications
A gelling composition and a process for wellbore treatment comprising injecting the composition into reservoirs are disclosed wherein the composition comprises a...
US-5,432,152 Invert drilling fluid
An environmentally friendly invert drilling fluid comprises a water-in-oil emulsion which includes (a) at least 50 volume percent of a low toxicity base oil, and...
US-5,432,151 Process for ion-assisted laser deposition of biaxially textured layer on substrate
A process for depositing a biaxially aligned intermediate layer over a non-single crystal substrate is disclosed which permits the subsequent deposition thereon...
US-5,432,150 High-Tc superconducting ceramic oxide products and macroscopic and microscopic methods of making the same
High-Tc superconducting ceramic oxide products and macroscopic and microscopic methods for making such high-Tc superconducting products. Completely sealed...
US-5,432,149 In-situ tunable Josephson weak links
A weak link is patterned from a high-temperature superconducting film using standard lithographic techniques. Once the area in which the weak link is to be...
US-5,432,148 Slow-release ammonium bicarbonate fungicide compositions
This invention provides a fungicide composition which is capable of in situ generation of ammonium bicarbonate when applied to plant foliage in the form of an...
US-5,432,147 Method of controlling fungal disease in cultivated plants
The present invention provides a method for controlling fungal disease in cultivated crops. The aqueous fungicide formulation which is applied to pre-harvest and...
US-5,432,146 Free-flowing bicarbonate fungicide compositions
The present invention provides a fungicidal fertilizer composition which contains ingredients which are biocompatible for purposes of agricultural applications,...
US-5,432,145 Protective layer transfer sheet
A protective layer transfer sheet, including a heat-resistant layer provided on one surface of a substrate film, and an adhesive layer, a releasable protective...
US-5,432,144 Thermal-transfer recording material and a thermal-transfer recording process
A thermal transfer recordimg material comprising a support having thereon a thermal transfer layer containing a dye represented by the following formula and a...
US-5,432,143 Method of producing an RBa.sub.2 Cu.sub.3 O.sub.y microcrystalline structure in which R denotes a lanthanide
A method of producing a microcrystalline RBa.sub.2 Cu.sub.3 O.sub.y structure where R denotes a lanthanide chosen from Y, La, Nd, Sm, Eu, Gd, Tb, Ho, Er, Tm, Yb...
US-5,432,142 Catalyst for alkene dimerization
A catalyst composition is disclosed that is useful for the dimerization of a normal 1-alkene containing 3-8 carbons. A supported alkali metal is employed as a...
US-5,432,141 Preparation of attrition resistant vanadium-antimony oxide catalysts
This invention relates to a process for preparing an attrition resistant vanadium-antimony oxide catalyst by adding to a vanadium-antimony oxide catalyst slurry...
US-5,432,140 Heat curable organopolysiloxane compositions, preformed latent platinum catalysts, and methods for making
Heat curable organopolysiloxane compositions are provided utilizing a vinyl silicone organopolysiloxane fluid, a silicon hydride siloxane and an effective amount...
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