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Patent # Description
US-7,192,757 Subtilase variants
The present invention relates to subtilase variants having a reduced tendency towards inhibition by substances present in eggs, such as trypsin inhibitor type...
US-7,192,756 Sialyltransferases from C. jejuni
This invention provides prokaryotic glycosyltransferases, including a bifunctional sialyltransferase that has both an .alpha.2,3- and an .alpha.2,8-activity. A...
US-7,192,755 Nicotianamine synthase and gene encoding the same
A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined....
US-7,192,754 Nomuraeae rileyi-origin ecdysteroid 22-oxidase and molt hormone inactivation system with the use of the same
A material and a system are provided that efficiently inactivate a molting hormone by means of a protein having ecdysteroid 22-oxidase activity.
US-7,192,753 Modified threonine deaminase
Nucleic acid sequences, vectors, recombinant host cells, transgenic plants, and methods for their preparation are disclosed. The nucleic acid sequences encode...
US-7,192,752 Real time electronic cell sensing systems and applications for cell-based assays
The present invention includes devices, systems, and methods for assaying cells using cell-substrate impedance monitoring. In one aspect, the invention provides...
US-7,192,751 Biosynthesis of amorpha-4,11-diene
Methods for synthesizing amorpha-4,11-diene synthase from isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism...
US-7,192,750 Mutant Actinosynnema pretiosum strain with increased maytansinoid production
A microorganism that is a mutant bacterial strain of the species Actinosynnema pretiosum, designated PF4-4, (ATCC PTA-3921), being capable of producing...
US-7,192,749 Use of the repressor glxR for the synthesis of lysine in Corynebacterium glutamicum
Isolated polypeptide sequence having the sequence of SEQ ID NO:1 or muteins thereof having the ability to bind cAMP and repress the expression of the aceB gene...
US-7,192,748 Isolated polynucleotides encoding phosphohexuloisomerase from Methylophilus methylotrophus
The present invention provides polypeptides and polynucleotides involved in C1 assimilation in Methylophilus methylotrophus and methods of producing amino acids...
US-7,192,747 Methods for producing L-amino acids
A methane-utilizing microorganism capable of producing L-amino acid, for example, bacteria belonging to type I, type X or type II in the taxonomic categorization...
US-7,192,746 .alpha.-Isomaltosyltransferase, process for producing the same and use thereof
The object of the present invention is to provide an .alpha.-isomaltosyl-transferring enzyme which forms a cyclotetrasaccharide having the structure of ...
US-7,192,745 Method for the determination of a nucleic acid using a control
The present invention is directed to a method for the determination of a target nucleic acid using a special control nucleic acid, a method for the amplification...
US-7,192,744 Targeted transfection of cells using a biotinylated dendrimer
The present invention relates to processes for the targeted transfection of cells, compositions which may be used for such processes, and corresponding...
US-7,192,743 Method of producing teicoplanin
Disclosed is a method of producing teicoplanin. The method includes purifying teicoplanin from a culture broth, obtained by culturing microorganisms capable of...
US-7,192,742 FO-6979 substances and process for producing the same
(Beauveria) sp. FO-6979 (FERM BP-6681), which belongs to the genus Beauveria and is capable of producing FO-6979-M0, -M1, -M2, -M3 and -M4 substances, is...
US-7,192,741 DNA sequences comprising gene transcription regulatory qualities and methods for detecting and using such DNA...
The invention is concerned with the systematic elucidation and identification of regulatory sequences. The invention provides among others screenings and...
US-7,192,740 Recombinant viral nucleic acids
The present invention relates to a recombinant viral nucleic acid selected from a (+) sense, single stranded RNA virus possessing a native subgenomic promoter...
US-7,192,739 Ligand-dependent protein splicing
Ligand-dependent inteins allow for modulation of a protein's activity in vivo. Upon binding of the ligand to the ligand-dependent intein inserted into the...
US-7,192,738 IGF binding proteins
IGFBP-3 fusion proteins are provided that are useful, for example, in cell-based assays, as IGF antagonists, and in mapping IGF-I and IGF-II binding sites on...
US-7,192,737 Methods and materials for increasing expression of recombinant polypeptides
The present invention provides novel methods and materials for increasing the expression of recombinant polypeptides. Methods and materials of the invention...
US-7,192,736 Nucleic acid molecules encoding cytotoxic conjugates that contain a chemokine receptor targeting agent
Nucleic acid moleucles that encode conjugates containing as a ligand a chemokine receptor targeting agent, such as a chemokine, and a targeted agent, such as a...
US-7,192,735 Phosphopantetheinyl transferases and uses thereof
The invention pertains to isolated phosphopantetheinyl transferases, such as the E. coli acyl carrier protein synthase, which transfer a phosphopantetheinyl...
US-7,192,734 Method of testing for the presence of microorganisms in a gaseous environment comprising hydrogen peroxide
The invention relates to a method of testing for the presence of microorganisms in a gaseous environment comprising hydrogen peroxide, comprising the following...
US-7,192,733 Methods and means for modulating PGE synthase activity
Isolated PGE synthase, provided from encoding nucleic acid. Methods of production and use. Assays for modulators, especially inhibitors, of PGE synthase activity.
US-7,192,732 Regulation of human caspase-1-like protease
Screening methods to identify candidate therapeutic agents using a newly identified human caspases-1-like protease.
US-7,192,731 Methods for efficient extraction of carotenoids using an esterase
A method of increasing a fraction of free carotenoids in a source of carotenoids in which at least some of the carotenoids are fatty acid esterified carotenoids...
US-7,192,730 Thermostable proteolytic enzymes and uses thereof in peptide and protein synthesis
The subject invention pertains to new thermostable enzymes and the use of these enzymes both in proteolysis as well as protein and polypeptide synthesis. The...
US-7,192,729 Methods for assaying homocysteine
The present invention relates to compositions and methods for assaying homocysteine (Hcy) and thus related moieties, e.g., S-adenosylhomocysteine (SAH) or...
US-7,192,728 Screening assays for agents that alter inhibitor of apoptosis (IAP) protein regulation of caspase activity
The present invention relates to an action between an inhibitor of apoptosis (IAP) protein and members of the caspase family of cell death proteases, for...
US-7,192,727 Reagent for measuring alanine aminotransferase activity
A reagent for measuring an alanine aminotransferase activity comprising L-alanine, 2-oxoglutaric acid, lactate dehydrogenase, and reduced nicotinamide adenine...
US-7,192,726 Method of using platelet contractile force and whole blood clot elastic modulus as clinical markers
Platelet contractile force and/or clot elastic modulus measurements are used to identify patients at risk for atherosclerosis or for bleeding during surgical...
US-7,192,725 Flagellin gene, flaC of Campylobacter
Purified and isolated nucleic acid molecules are provided which encode a FlaC flagellin protein of a strain of Campylobacter, particularly C. jejuni, or a...
US-7,192,724 Method for differentiating irritable bowel syndrome from inflammatory bowel disease (IBD) and for monitoring...
A method for aiding in differentiating irritable bowel syndrome from inflammatory bowel disease by determining the level of total endogenous human lactoferrin in...
US-7,192,723 G protein-coupled receptor protein, its DNA and ligand thereof
The polypeptides in the present invention possess the effects of promoting and inhibiting the secretion of prolactin, and are thus useful as drugs for the...
US-7,192,722 Phenethanolamine-derived haptens, immunogens, antibodies and conjugates
The present invention relates to a method for preparing haptens of formulae I and II that are useful in the preparation of immunogens, antibodies and conjugates,...
US-7,192,721 Universal rapid test and method for detection of tuberculosis in multiple host species
A universal test apparatus for detecting tuberculosis (TB) in any of many different species of non-primate mammals is provided. The universal test apparatus...
US-7,192,720 Array-based epitope-captured antibody display
Reagents and methods for detecting target proteins in a sample are provided. The reagents include a replicable genetic package, a protein displayed on an...
US-7,192,719 Antibodies specific for papillary fibroblasts as markers for skin quality
Whether or not a sample of skin or of a skin equivalent contains such amount of a papillary fibroblast population as to be considered a normal skin is determined...
US-7,192,718 Methods for identifying a substance which specifically binds to an osteoclastogenesis inhibitory factor-binding...
The present invention relates to a novel protein which binds to Osteoclastogenesis Inhibitory Factor (OCIF-binding molecule; OBM), a process for preparing the...
US-7,192,717 GASP1: a follistatin domain containing protein
The present invention relates to the use of a protein, GASP1, comprising at least one follistatin domain to modulate the level or activity of growth and...
US-7,192,716 Organ transplant rejection and associated conditions
Protein markers associated with organ transplant rejection and associated conditions are disclosed, and in particular materials and methods relating to the...
US-7,192,715 Diagnostics and therapy of epstein-barr virus in autoimmune disorders
Data consistent with autoimmune disease being caused by Epstein-Barr virus are shown. Based on this evidence, an effective vaccine would prevent the autoimmune...
US-7,192,714 LDL receptor signaling assays
The invention provides methods and compositions for modeling and detecting LDL receptor transmembrane signaling by detecting proteolysis of an LDL receptor...
US-7,192,713 Stabilized compounds having secondary structure motifs
The present invention provides novel stabilized crosslinked compounds having secondary structure motifs, libraries of these novel compounds, and methods for the...
US-7,192,712 Common marmoset-derived beta-actin gene and use thereof
The present invention provides a common marmoset-derived beta-actin gene and use thereof.
US-7,192,711 Compositions and methods involving methyladenosine phosphorylase in the diagnosis and treatment of...
Disclosed are novel nucleic acid and peptide compositions comprising methylthioadenosine phosphorylase (MTAP) and methods of use for MTAP amino acid sequences...
US-7,192,710 Methods and compositions for high throughput identification of protein/nucleic acid binding pairs
Methods and compositions for high-throughput identification of protein/nucleic acid binding pairs are provided. In the subject methods, a nucleic acid probe...
US-7,192,709 Methods for identification, assessment, prevention, and therapy of cancer
The present invention relates to the newly identified cancer therapeutic targets and biomarkers. These targets/biomarkers are overexpressed in carcinomas...
US-7,192,708 Nucleic acid enzyme biosensors for ions
A method of detecting the presence of an ion includes contacting a nucleic acid enzyme with a sample suspected of containing the ion, where the enzyme contains a...
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