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| Patent # | Description |
|---|---|
| US-9,611,259 |
Substituted pyridine derivatives useful as C-FMS kinase inhibitors The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives... |
| US-9,611,258 |
Dual MEK/PI3K inhibitors and therapeutic methods using the same Dual inhibitors of MEK and PI3K and compositions containing the same are disclosed. Methods of using the dual MEK/PI3K inhibitors in the treatment of diseases... |
| US-9,611,257 |
PRMT5 inhibitors and uses thereof Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present... |
| US-9,611,256 |
Alkyne-, azide- and triazole-containing flavonoids as modulators for
multidrug resistance in cancers A triazole bridged flavonoid dimer compound library was efficiently constructed via the cycloaddition reaction of a series of flavonoid-containing azides (Az... |
| US-9,611,255 |
Process for total synthesis of flavonoid compounds and isomers thereof The present invention relates to the a process for total synthesis of flavonoid compounds of general formula I and isomers thereof ##STR00001## wherein R.sub.1... |
| US-9,611,254 |
Triazole compounds and their use as gamma secretase modulators The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical... |
| US-9,611,253 |
Solid forms comprising optically active pyrazolylaminoquinazoline,
compositions thereof, and uses therewith Solid forms comprising pyrazolylaminoquinazoline, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the... |
| US-9,611,252 |
Therapeutic inhibitory compounds Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting plasma... |
| US-9,611,251 |
Substituted piperidine compounds and their use as orexin receptor
modulators The present invention is directed to compounds of Formula I: wherein X is CR.sub.1 or N; Y is CR.sub.2 or N; Z is NH or O; R.sub.1 is alkoxy, triazolyl,... |
| US-9,611,250 |
Process for preparing
4-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridyl)-5-methoxypyridi-
... The present invention relates to a novel process for preparing the compound 4-(cyclopropylmethoxy)-N-(3,5-di-chloro-1-oxido-4-pyridyl)-5-met- ... |
| US-9,611,249 |
1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta
inhibitors The present invention relates to the 1H-indazole-3-carboxamide compounds having the following general formula (I) as glycogen synthase kinase 3 beta... |
| US-9,611,248 |
Chemical compounds The invention relates to pyrrolone compounds of the formula (I) ##STR00001## wherein X, R.sup.1, R.sup.2, R.sup.3 and A are as defined in the specification.... |
| US-9,611,247 |
Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine 3-(3-Chloro-1H-pyrazol-1-yl)pyridine is prepared by cyclizing 3-hydrazinopyridine-dihydrochloride with acrylonitrile to provide ... |
| US-9,611,246 |
Compositions, apparatus, systems, and methods for resolving electronic
excited states The present disclosure relates, according to some embodiments, to molecules, including conjugated fused polycyclic molecules, that may receive excited state... |
| US-9,611,245 |
Diarylalkylamine REV-ERB antagonists and their use as medicaments The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical... |
| US-9,611,244 |
Cyclic compounds The present invention provides compounds having a Toll-like receptor 4 (TLR4) signaling inhibitory action useful as preventive and therapeutic drugs of... |
| US-9,611,243 |
Method of producing beraprost An improved method is described for making single isomers of synthetic benzoprostacyclin analogue compounds, in particular the pharmacologically active 314-d... |
| US-9,611,242 |
Process for preparation of dronedarone by N-butylation The invention relates to a compound of formula (II) ##STR00001## and salts thereof. Also described herein are processes for the preparation of a compound of... |
| US-9,611,241 |
Conversion of fructose-containing feedstocks to HMF-containing product The present invention relates generally to processes for converting fructose-containing feedstocks to a product comprising 5-(hydroxymethyl)furfural (HMF) and... |
| US-9,611,240 |
14-hydroxy-docosahexaenoic acid compounds The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogs, their preparation, isolation, identification, purification and uses thereof. |
| US-9,611,239 |
14-hydroxy-docosahexaenoic acid compounds The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogues, their preparation, isolation, identification, purification and uses thereof. |
| US-9,611,238 |
14-hydroxy-docosahexaenoic acid compounds The invention describes novel 14-hydroxy docosahexaenoic acid (DHA) analogues, their preparation, isolation, identification, purification and uses thereof. |
| US-9,611,237 |
Phosphor materials and related devices A phosphor material is presented that includes a blend of a first phosphor, a second phosphor and a third phosphor. The first phosphor includes a composition... |
| US-9,611,236 |
Method for producing ethylene oxide [Problem] To provide a method by which an amount of production of ethylene glycol as a by-product is reduced and a yield of ethylene oxide can be improved in a... |
| US-9,611,235 |
Methods and compositions related to a retinoid receptor-selective pathway Provided herein are methods and compositions related to a retinoid receptor-selective pathway. As described herein, this pathway can be targeted to manipulate a... |
| US-9,611,234 |
Choline cocrystal of epalrestat The invention relates to a novel choline cocrystal of 5-[(1Z,2E)-2-methyl-3-phenylpropenylidene]-4-oxo-2-thioxo-3-thiazolidinea- cetic acid. The preparation and... |
| US-9,611,233 |
Organic compound The present invention provides an organic compound to be used in an electrochromic device. The organic compound has excellent oxidation-reduction repeating... |
| US-9,611,232 |
Oxazolidinone and imidazolidinone compounds The invention provides compounds having the general formula I ##STR00001## wherein n, R.sup.1, R.sup.2a, R.sup.2b, R.sup.3a and R.sup.3b are as herein defined,... |
| US-9,611,231 |
Method for preparing 3-trifluoromethyl chalcones Disclosed is a method for preparing a compound of Formula 1 wherein Q and Z are as defined in the disclosure comprising distilling water from a mixture... |
| US-9,611,230 |
1,3,4-oxadiazole benzoic acid compounds and their use for nonsense
suppression and the treatment of disease The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by... |
| US-9,611,229 |
1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor
related diseases and disorders The present invention relates to new 1,2,3-triazole-amine derivatives, having affinity for sigma receptors, especially sigma-1 receptor, as well as to the... |
| US-9,611,228 |
Stabilized compositions and methods of manufacture A method for stabilization of potent alkanone-heterocyclic flavorants in dry powder form is provided. Coordination of alkanone-heterocyclic flavorants to... |
| US-9,611,227 |
Antitumor effect potentiator and antitumor agent The present invention provides an antitumor effect potentiator for enhancing antitumor activity of an antitumor agent comprising tegafur in a therapeutically... |
| US-9,611,226 |
Preparation method for azoxystrobin Disclosed in the present invention is a preparation method of azoxystrobin having a structure as shown by formula (1), the method comprising: a) performing an... |
| US-9,611,225 |
Process for preparation of androgen receptor antagonist The present invention provides an isopropanol solvate of enzalutamide. The present invention also provides a process for the preparation of androgen receptor... |
| US-9,611,224 |
Antiproliferative benzo [B] azepin-2-ones Disclosed are compounds of Formula (I) or pharmaceutically acceptable salts thereof, wherein W, X, Y, Z, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are described in... |
| US-9,611,223 |
3-aryl-5-substituted-isoquinolin-1-one compounds and their therapeutic use The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain ... |
| US-9,611,222 |
Pyridine compounds and the uses thereof The invention relates to substituted pyridine compounds of Formula (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein... |
| US-9,611,221 |
Histone demethylase inhibitors The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted amidopyridine or... |
| US-9,611,220 |
Inhibitors of histone demethylases The present application discloses compounds capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment... |
| US-9,611,219 |
Inhibitors of histone demethylases The present application discloses compounds capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment... |
| US-9,611,218 |
Metal-organic materials and method for preparation The present invention provides metal-organic materials, more specifically organometallic polymers, comprising polypyridyl organic ligands such as ... |
| US-9,611,217 |
Synthetic processes of carprofen Methods and intermediates for the synthesis of carprofen and its derivatives starting from cyclohexanone are disclosed. |
| US-9,611,216 |
Compound with branching alkyl chains, method for preparing the same, and
use thereof in photoelectric device The invention discloses a compound having branching alkyl chains, the method for preparing the same and use thereof in photoelectric devices. By applying the... |
| US-9,611,215 |
Nucleophile-reactive sulfonated compounds for the (radio)labelling of
(bio) molecules; precursors and... Nucleophile-reactive sulfonated compounds used as precursors to (radio)labelled (bio)molecules are produced by pre-introduction of a nucleophilic compound R*... |
| US-9,611,214 |
N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake
inhibitors The present invention provides a pyrrolidine compound of General Formula (1) ##STR00001## or a salt thereof, wherein R.sup.101 and R.sup.102 are each... |
| US-9,611,213 |
Functionalized 1,3-benzene diols and their method of use for the treatment
of hepatic encephalopathy Pharmaceutical compositions of the invention include novel functionalized 1,3-benzenediols having a disease-modifying action in the treatment of hepatic... |
| US-9,611,212 |
Polyol estolides and methods of making and using the same Provided herein are polyol estolide compounds. Polyol estolides may be prepared by contacting a polyol with an estolide compound. Also provided are compositions... |
| US-9,611,211 |
1-(2-acyloxyethyl)cyclopropyl sulfonate compound, 3-halomethyl-3-butenyl
carboxylate compound, and method for... Provided is a simple, selective and efficient method for producing 4-alkyl-3-methylenebutyl carboxylates such as 7-methyl-3-methylene-7-octenyl propionate. More... |
| US-9,611,210 |
Single-pot synthesis of dialkyl carbonates using catalyst from natural
resource The present invention relates to a single-pot method for preparing dialkyl carbonates, the method comprises reaction of alkylene oxide with aliphatic or cyclic... |
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