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Patent # Description
US-9,708,625 Methods of controlling seed size in plants
This invention relates to the identification of a regulator protein (termed CYP78A6, or EOD3) which controls the size of plant seeds and organs in Arabidopsis...
US-9,708,624 Modulation of expression of acyltransferases to modify hydroxycinnamic acid content
The invention provides methods of engineering plants to modulate hydroxycinnamic acid content. The invention additionally provides compositions and methods...
US-9,708,623 Polysaccharide synthases
The present invention relates generally to polysaccharide synthases. More particularly, the present invention relates to (1,3;1,4)-.beta.-D-glucan synthases....
US-9,708,622 Transgenic plants with altered nitrate levels in leaves
The present invention relates to genetic constructs, which can be used in the preparation of transgenic plants. The constructs can have the ability of reducing...
US-9,708,621 Methods and means for obtaining modified phenotypes
Methods and means are provided for reducing the phenotypic expression of a nucleic acid of interest in eukaryotic cells by providing aberrant, preferably...
US-9,708,620 Recombinant DNA constructs and methods for controlling gene expression
The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs...
US-9,708,619 Methods for controlling gene expression using ta-siRNA
The present invention is in the field of genetics, especially plant genetics, and provides agents capable of controlling gene expression. More specifically the...
US-9,708,618 Constructs for expressing transgenes using regulatory elements from brachypodium ubiquitin genes
Provided are constructs and methods for expressing a transgene in plant cells and/or plant tissues using the regulatory elements, including the promoters and/or...
US-9,708,617 Method of anaerobic tissue-targeted gene expression initiated by alcohol dehydrogenase promoter and the...
A proteomic screening method for anaerobic-specific and expression-effective promoter, and a method of specially delivering and selectively stably expressing...
US-9,708,616 Production of recombinant proteins utilizing non-antibiotic selection methods and the incorporation of...
Provided herein are methods and compositions for expression of a nucleic acid construct comprising nucleic acids encoding a) a recombinant polypeptide, and b) a...
US-9,708,615 Therapeutic compositions
This application relates to therapeutic siRNA agents and methods of making and using the agents.
US-9,708,614 Antisense design
A novel class of pharmaceuticals which comprises a Locked Nucleic Acid (LNA) which can be used in antisense therapy. These novel oligonucleotides have improved...
US-9,708,612 Methods and compositions using miR-3151 in the diagnosis and treatment of thyroid cancer
Compositions comprising therapeutic oligonucleotide miR-3151 compounds that target the expression of genes associated with tumorigenesis or cell transformation...
US-9,708,611 RNA targeting in alpha-synucleinopathies
Therapies and assays to screen for small molecules that can have therapeutic use in the control of neurodegenerative diseases such as Parkinson's and other...
US-9,708,610 Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
The present invention provides compositions comprising at least one oligomeric compound comprising an alternating motif and further include a region that is...
US-9,708,609 Methods to screen compounds for regulating USF1 activity and methods and compounds to treat cardiometabolic and...
The deficiency of Usf1 confers a remarkable number of clinically relevant beneficial metabolic effects in mice via activation of brown adipose tissue. The Usf1...
US-9,708,608 Methods for producing a population of pancreatic beta-cells
The present invention relates to an in vitro or ex vivo method for producing a population of pancreatic beta-cells, comprising the step of inhibiting the...
US-9,708,607 Modified RNAi agents
One aspect of the present invention relates to double-stranded RNAi (dsRNA) duplex agent capable of inhibiting the expression of a target gene in vivo. The...
US-9,708,606 RNA products and uses thereof
The present invention relates to small RNAs, inhibitors thereof, inhibitors of enzymes producing thereof, and their use to modulate the response of a cell to a...
US-9,708,605 Methods and compositions for the specific inhibition of MCL1 by double-stranded RNA
This invention relates to compounds, compositions, and methods useful for reducing MCL1 target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate...
US-9,708,604 Treatment of delta-like 1 homolog (DLK1) related diseases by inhibition of natural antisense transcript to DLK1
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Delta-like (1) homolog (DLK1), in particular, by...
US-9,708,603 Method for amplifying cDNA derived from trace amount of sample
The problem to be solved by the present invention is to provide a method for preparing a sample for comprehensively and accurately analyzing gene expression in...
US-9,708,602 Screening for inhibitors of ribosome biogenesis
The invention relates to a method and a prokaryotic cell for identifying a compound, which interferes with ribosome biogenesis, assembly and/or degradation. The...
US-9,708,601 Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant...
The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method...
US-9,708,600 Biologic sample collection devices and methods of production and use thereof
Collection devices and kits for biological sample collection include a biologic sample collection device having a hydrophilic swab matrix that includes a...
US-9,708,599 Sample processing methods
A method of processing a sample may include introducing a sample into a vessel, the vessel having proximal and distal ends, the sample being introduced into the...
US-9,708,598 Methods of using improved polymerases
This invention provides for methods of sequencing and performing polymerase reactions using an improved generation of nucleic acid polymerases. The improvement...
US-9,708,597 Electric pulse generation systems using capacitive coupling
In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the...
US-9,708,596 Mutant CyaA polypeptides and polypeptide derivatives suitable for the delivery of immunogenic molecules into a cell
The invention relates to mutant CyaA/E570Q+K860 polypeptides suitable for use as proteinaceous vectors for delivering one or more molecules of interest into a...
US-9,708,595 Stabilized alpha-galactosidase and uses thereof
Multimeric protein structures comprising at least two alpha-galactosidase monomers being covalently linked to one another via a linking moiety are disclosed...
US-9,708,594 Thermostable .beta.-glucosidase
An isolated recombinant thermostable .beta.-glucosidase includes a polypeptide including the amino acid sequence of SEQ ID NO: 1 and at least one region...
US-9,708,593 Oleaginous bacterial cells and methods for producing lipids
This invention relates to cells and methods for producing lipids using cellulosic carbon source. More specifically the invention relates to oleaginous bacterial...
US-9,708,592 Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
Provided are isolated polypeptides having cellulolytic enhancing activity, and polynucleotides encoding the polypeptides. Also provided are nucleic acid...
US-9,708,591 Polypeptides having endoglucanase activity and polynucleotides encoding same
Provided are isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. Also provided are nucleic acid...
US-9,708,590 Crystal structure of human .alpha.-N-acetylglucosaminidase
The present invention provides the three-dimensional structure of human .alpha.-N-acetylglucosaminidase (NAGLU) protein. This crystallographic information is...
US-9,708,589 Compositions and methods for custom site-specific DNA recombinases
The invention relates to biotechnology and provides novel compositions and methods for sequence-specific or sequence-directed transcription activator-like...
US-9,708,588 Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs
The present disclosure provides engineered transaminase polypeptides for the production of amines, polynucleotides encoding the engineered transaminases, host...
US-9,708,587 P450-BM3 variants with improved activity
The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a...
US-9,708,586 Amadoriase having altered substrate specificity
This invention provides an amadoriase having high substrate specificity to fructosyl valyl histidine. Such amadoriase comprises substitution of one or more...
US-9,708,585 Influenza virus reassortment
New influenza donor strains for the production of reassortant influenza A viruses are provided.
US-9,708,584 Medium composition for rejuvenating stem cells
The present invention relates to a medium composition for transforming stem cells from an aged person into young stem cells, and more particularly to a medium...
US-9,708,583 Methods for stimulating antigen-specific T cell responses
The present invention relates to methods for stimulating antigen-specific T cell responses. In particular, the invention relates to a method for stimulating...
US-9,708,582 Method of differentiating stem cells
The present disclosure provides methods of generating germ layers from stem cells comprising culturing the stem cells in a culture media having osmolality...
US-9,708,580 Bacterial culture media and methods for their preparation and use
Provided herein are methods and compositions for bacterial cellulose production. In some embodiments, the methods and compositions involve or are made from...
US-9,708,579 Lactic acid bacteria fermented substance and fermented milk food product containing the same
An object of the invention is to provide a lactic acid bacteria fermentation product, which has been obtained by culturing lactic acid bacteria on a medium...
US-9,708,578 Measuring unit to be attached to cell culture container, cell culture container, and cultivation condition...
A measuring unit which is to be attached to a cell culture container configured to accommodate cells to be cultured and a culture solution, includes: a measurer...
US-9,708,577 Apparatus for controlling ammonia and a method for controlling ammonia
An method for controlling ammonia concentration of a culture medium contained in a culture tank, by using an ammonia-controlling apparatus comprising at least...
US-9,708,576 Culture flask
A culture flask comprising a culture chamber in a flask body comprising an even bottom wall with a growth surface on the top side, an even cover wall at a...
US-9,708,575 Systems and methods for wine processing
Embodiments of the present disclosure are directed to extracting the liquid from a container (such as a bottle of wine) in varying amounts at a desired serving...
US-9,708,574 Laundry scent additive
A laundry scent additive having polyethylene glycol and perfume. The laundry scent additive enables consumers to control the amount of scent imparted to their...
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