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Patent # Description
US-9,707,255 Microporous zirconium silicate for the treatment of hyperkalemia in hypercalcemic patients and improved...
The present invention relates to novel calcium-containing microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions,...
US-9,707,254 Method for prevention and treatment of cancer, tuberculosis and related diseases
A method for preventing and treating one or more disease states including the steps of altering the diet of an individual and then administering a drug to the...
US-9,707,253 High-loading, controlled-release magnesium oral dosage forms and methods for making and using same
Disclosed are high loading, controlled-release dosage forms for oral administration of magnesium salts. For example, an oral dosage form can comprise from about...
US-9,707,252 Synthetic sealants
A biocompatible synthetic macromer composition is provided which includes a first polymer having stiffening linkages and at least one amine group, and a second...
US-9,707,251 Siloxane-based artificial blockage to control bleeding
Two siloxane-based mixtures combine to form a soft or semi-solid matrix for forming an artificial blockage to control bleeding, particularly moderate to severe...
US-9,707,250 Hydrophobically modified antisense oligonucleotides comprising a triple alkyl chain
The present invention concerns an oligonucleotide modified by substitution at the 3' or the 5' end by a moiety comprising at least three saturated or...
US-9,707,249 Trehalulose-containing composition, its preparation and use
A trehalulose-containing composition, its preparation and use.
US-9,707,247 Compositions for administration of zoledronic acid or related compounds for treating low back pain
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, such as zoledronic acid in an acid or a salt form, or in a molecular...
US-9,707,246 Substituted (3S,11AR)-N-[(2,4-difluorophenyl)methyl]-6-oxy-3-methyl-5,7-dioxo-2,3,5,7- ...
The invention is directed to a method for treatment of viral infections, particularly HIV infection. The method involves administering compounds which are...
US-9,707,245 Neridronic acid for treating complex regional pain syndrome
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, can be used to treat or alleviate pain or related conditions such as...
US-9,707,244 Compositions and methods for treating conditions that affect epidermis
The present invention relates to the compositions and methods for treating or alleviating conditions that affect the epidermis (e.g., wrinkles, sun damaged...
US-9,707,243 Topical composition with vitamin D3
The topical composition with Vitamin D3 includes Vitamin D3, one or more aromatic oils, and aloe vera gel. Vitamin D3 is soluble in aromatic oils, and aloe vera...
US-9,707,242 Use of 25-hydroxyvitamin D3 to enhance executive functions
This invention relates to the use of 25-hydroxyvitamin D3 (25-OH D3) to increase or maintain or alternatively, to lessen the decrease of the cognitive element...
US-9,707,241 Nutritional intervention for improving muscular function and strength
The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D...
US-9,707,240 Nutritional compositions with lipid globules with a core comprising vegetable lipids and a coating comprising...
The present invention relates to a nutritional composition for infants and/or toddlers comprising a lipid component which has a large lipid globule size. The...
US-9,707,238 Oil-in-water method for making polymeric implants containing a hypotensive lipid
Biocompatible microparticles include an ophthalmically active cyclic lipid component and a biodegradable polymer that is effective, when placed into the...
US-9,707,237 Compound useful for the treatment of degenerative and inflammatory diseases
A novel compound able to inhibit JAK is disclosed, that comprises a compound according to Formula I: ##STR00001## or a pharmaceutically acceptable salt...
US-9,707,236 Combination methods for treating cancers
Disclosed are methods for treating a cancer in a subject (e.g., a human) in need thereof, comprising administering to the subject a therapeutically effective...
US-9,707,235 Protection of cells from degeneration and treatment of geographic atrophy
Therapeutic uses P2X.sub.7 inhibition and inhibition of IRAK1 and/or IRAK4, methods protecting a cell, and screening methods for identifying inhibitors are...
US-9,707,234 Spirocyclic hetercycle compounds useful as HIV integrase inhibitors
The present invention relates to Spirocyclic Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, R.sup.1,...
US-9,707,233 Heterocyclylamines as PI3K inhibitors
The present invention provides heterocyclylamine derivatives of Formula I: ##STR00001## wherein the variables are defined herein, that modulate the activity...
US-9,707,231 Compositions and methods for reduction of amyloid-beta load
The present invention relates to methods and compositions for modulating levels of amyloid-.beta. peptide (A.beta.) exhibited by non-neuronal (i.e., peripheral)...
US-9,707,230 Activators of human pyruvate kinase
Disclosed are pyruvate kinase M2 activators, which are, bis sulfonamide piperazinyl compounds of Formula (I) and 2,4-disubstituted ...
US-9,707,229 Compositions and methods for treating an infection
The present application relates to compounded compositions, methods of making compounded compositions, kits comprising compounded compositions, containers...
US-9,707,228 Dry powder formulation
A dry powder formulation comprising a combination of at least a first pharmaceutically active quinolone and a second pharmaceutically active quinolone.
US-9,707,227 Treatment of T-cell mediated diseases
The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The...
US-9,707,226 Nasal drug products and methods of their use
Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are...
US-9,707,225 Combinations of opioid/TLR4 antagonist and acetyl-para-aminophenol (APAP) for use in the treatment of pain
Disclosed are compositions for the treatment of pain comprising a first compound and a second compound, the first compound is an opioid antagonist that treats...
US-9,707,224 Immediate release abuse-deterrent granulated dosage forms
Described are immediate release oral dosage forms that contain abuse-deterrent features. In particular, the disclosed dosage forms provide deterrence of abuse...
US-9,707,223 Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
The present invention provides heteroaryl ketone fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.
US-9,707,222 Isoquinoline alkaloid derivative for activating AMP-dependent protein kinase
The present invention provides a method for activating the AMP-dependent protein kinase (AMPK) in a subject comprising administering the subject with a...
US-9,707,221 Methods of treating cancer patients with farnesyltransferase inhibitors
The present invention relates to the field of molecular biology and cancer biology. Specifically, the present invention relates to methods of treating a subject...
US-9,707,220 Scopolamine for the treatment of depression and anxiety
Provided are methods and compositions for the treatment of depression and anxiety. The compositions contain scopolamine, or an analog thereof, and can...
US-9,707,219 Losmapimod for use in treating glomerular disease
The present invention relates to a method of treating a glomerular disease with 6-(5-cyclopropylcarbamoyl-3-fluoro-2-methyl-phenyl)-N-(2,2-dimethylpropyl- ...
US-9,707,218 Derivatives of pyrazole-substituted amino-heteroaryl compounds
This invention relates to novel pyrazole-substituted amino-heteroaryl compounds of Formula I: ##STR00001## and pharmaceutically acceptable salts thereof. This...
US-9,707,217 Dose-dumping resistant controlled release dosage form
The present invention provides a simple and improved dose form that is capable of providing a controlled release of methylphenidate contained in the core...
US-9,707,216 Topical retinoid compositions
The present application relates to topical compositions. In particular, the present application relates to a topical composition comprising retinoid as active...
US-9,707,215 Inhibitors of hepatitis C virus polymerase
The present invention provides, among other things, compounds represented by the general Formula I: and pharmaceutically acceptable salts thereof, wherein X, Y,...
US-9,707,213 Compositions, methods and kits for reducing lipid levels
Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of...
US-9,707,212 S-nitrosoglutathione reductase inhibitors
The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and...
US-9,707,211 Trifluoromethyl pyrazolyl guanidine F.sub.1F.sub.0-ATPase inhibitors and therapeutic uses thereof
The invention provides trifluoromethyl pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using trifluoromethyl pyrazolyl...
US-9,707,210 Methods of treating muscular dystrophy
Disclosed herein are .alpha.7.beta.1 integrin modulatory agents and methods of using such to treat conditions associated with decreased .alpha.7.beta.1 integrin...
US-9,707,209 Use of NK-1 receptor antagonists in pruritus
The invention relates to methods for treating pruritus with NK-1 receptor antagonists such as serlopitant. The invention further relates to pharmaceutical...
US-9,707,208 Use of NK-1 receptor antagonist serlopitant in pruritus
The invention relates to methods for treating pruritus with NK-1 receptor antagonists such as serlopitant. The invention further relates to pharmaceutical...
US-9,707,207 Method for diagnosing, preventing, and treating neurological diseases
The invention provides for methods of treating autism associated with Desulfovibrio overgrowth in the gastrointestinal tract of a patient, said method...
US-9,707,206 Mast cell stabilizers treatment for systemic disorders
Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders, are provided. Some embodiments...
US-9,707,205 S1P receptors modulators and their use thereof
The invention relates to novel compounds that have S1P receptor modulating activity. Further, the invention relates to a pharmaceutical comprising at least one...
US-9,707,204 Treatment of breast cancer
The present invention relates to the use of a liposomal preparation for the manufacture of a pharmaceutical composition and the use of such a composition for...
US-9,707,203 Methods of killing bacteria and preventing or treating bacterial infection with oxidation products of safranal...
A method of killing bacteria. The method includes contacting the bacteria with an effective amount of at least one oxidation product of safranal selected from...
US-9,707,202 Certain chemical entities, compositions, and methods
Chemical entities that are curcumin derivatives, pharmaceutical compositions and methods of treatment of cancer are described.
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