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Patent # Description
US-9,763,938 Substituted quinoxalines as positive allosteric modulators of mGluR4
The present invention relates to the use of novel quinoxaline derivatives of formula (I) ##STR00001## as positive allosteric modulators for modulating...
US-9,763,937 Aminoheteroaryl benzamides as kinase inhibitors
The present invention provides a compound of Formula (I) or a salt thereof; ##STR00001## and therapeutic uses of these compounds. The present invention...
US-9,763,936 Flibanserin for the treatment of urinary incontinence and related diseases
The invention relates to the use of Flibanserin for the treatment or prevention of urinary incontinence and related diseases. In a further embodiment, the...
US-9,763,935 Controlled release sterile injectable aripiprazole formulation and method
A controlled release sterile freeze-dried aripiprazole formulation is provided which is formed of aripiprazole of a desired mean particle size and a vehicle...
US-9,763,934 Synergistic effect of poloxamer-based composition and itraconazole on fungus and yeast
A pharmaceutical composition for the treatment of yeast and fungal infections is provided. The composition may include a micronized poloxamer composition as...
US-9,763,933 Tamper resistant dosage forms
The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of...
US-9,763,932 Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic...
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically,...
US-9,763,931 Buprenorphine-wafer for drug substitution therapy
The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral,...
US-9,763,930 Composition and methods for treating skin conditions
Compositions and methods for treatment of conditions affecting skin and/or mucosal surfaces of a subject that make use of an imidazoquinoline compound and a...
US-9,763,929 Tablettable chewing gums
The invention relates to certain nicotine chewing gums that provide for a high rate of buccal absorption and high plasma concentrations, in particular over the...
US-9,763,928 Multi-layer nicotine-containing pharmaceutical composition
The invention provides a multi-layered pharmaceutical composition comprising two or more formulations with varying properties. In some embodiments, the...
US-9,763,927 Indazole inhibitors of the Wnt signal pathway and therapeutic uses thereof
Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole...
US-9,763,926 Methylphenidate extended release chewable tablet
An oral methylphenidate extended release tablet is described, which can be scored and still retain its extended release profile. The tablet contains a...
US-9,763,925 Antibacterial compounds
Disclosed are compounds of formula (I): ##STR00001## which are of use in the treatment of bacterial diseases and infections, to compositions containing those...
US-9,763,924 Aminoester derivatives
Compounds of formula (I), defined herein, are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for the...
US-9,763,923 Composition for reducing senescence of cell or subject including BRAF inhibitor and use thereof
Provided is a method of reducing senescence in a cell or subject, or treating or preventing a symptom or disease associated therewith, by administering a BRAF...
US-9,763,922 Therapeutic compounds and uses thereof
The present invention relates to compounds of formula (I) or formula (II): ##STR00001## and to salts thereof, wherein R.sup.1-R.sup.4 of formula (I) and...
US-9,763,921 Dosing regimens of celgosivir for the treatment of dengue
Methods of treating a dengue virus (DENV) infection in a human subject, comprising administering to the human subject a compound of Formula (I), or...
US-9,763,920 Solid dispersions comprising tacrolimus
A pharmaceutical composition comprising tacrolimus (FK-506) dissolved and/or dispersed in a hydrophilic or water-miscible vehicle to form a solid dispersion or...
US-9,763,919 Detecting and treating growth hormone deficiency
Described herein is a new oral method for using MK-0677 for detecting growth hormone (GH) deficiency (GHD). Also described is a method of treating growth...
US-9,763,918 Compositions and methods for treating chronic urticaria
Disclosed herein are methods of treating conditions, which may be associated with elevated levels of mast cells, basophils, eosinophils, or a combination...
US-9,763,917 Clonidine formulations in a biodegradable polymer carrier
Effective treatments of pain for extended periods of time are provided. Through the administration of an effective amount of clonidine at or near a target site,...
US-9,763,915 Adjuvants in anti-cancer chemotherapy
The present invention provides a 1,2,4-trioxane or a pharmaceutically acceptable salt, ester, solvate, tautomer or stereoisomer thereof for use as an adjuvant...
US-9,763,914 Deuterated benzopyran compounds and application thereof
The present invention discloses deuterated benzopyran compounds having structure features as shown in Formula (I), or pharmaceutically acceptable salts or...
US-9,763,912 Compositions, methods of use, and methods of treatment
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or...
US-9,763,911 Prostacyclin compositions for regulation of fracture repair and bone formation
The present disclosure provides a prostacyclin coated implant to enhance fracture repair and bone formation comprising: an implant; and a prostacyclin coating...
US-9,763,910 Combination therapy for treating cancer
Disclosed is a method of treating a subject having non-small cell lung cancer. The method includes administering to the subject a therapeutically effective...
US-9,763,909 Methods for treating inflammation and pain
The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an ...
US-9,763,908 Composition containing monoacetyldiglyceride compound as active ingredient for preventing or treating atopic...
The present invention relates to a pharmaceutical composition, functional health food composition, quasi-drug composition, and cosmetic composition containing a...
US-9,763,907 Use of derivatives of polyunsaturated fatty acids as medicaments
Use of polyunsaturated fatty acid derivatives as medicaments or functional foods. The present invention relates to the use of 1,2-fatty acid derivatives in the...
US-9,763,906 Use of derivatives of polyunsaturated fatty acids as medicaments
Use of polyunsaturated fatty acid derivatives as medicaments or functional foods. The present invention relates to the use of 1,2-fatty acid derivatives in the...
US-9,763,905 Therapeutic target for the treatment of cancers and related therapies and methods
Disclosed herein are compositions and methods for treating or preventing certain cancers in a subject. In certain embodiments such compositions and methods...
US-9,763,904 Position-specific asymmetric deuterium enriched catecholamine derivatives and medicaments comprising said compounds
Herein described are deuterated catecholamine derivatives of the general Formula I ##STR00001## wherein, R.sub.1 is deuterium, R.sub.2, and R.sub.3 are...
US-9,763,903 Compositions and methods for treating intestinal hyperpermeability
The present invention provides methods, compositions, and kits for treating intestinal hyperpermeability in a subject in need thereof, including conditions such...
US-9,763,902 Method for preparation of N-acetyl cysteine amide
The present application discloses an efficient process for the preparation of N-acetyl-L-cysteine amide (NACA) starting with N-acetyl-L-cysteine.
US-9,763,901 Treatment of hepatitis C using histone deacetylase inhibitors
The present invention relates to method of treatment of hepatitis C using bufexamac or a derivative thereof. The methods of the present invention can be used in...
US-9,763,900 Chemical chaperonins as novel molecular modulators of beta protein aggregation present in conformational diseases
This invention relates to chemistry and biochemistry applied to the field of medicine and is referred to a new method of prevention and therapeutic treatment of...
US-9,763,899 Iron chelators and use thereof for reducing transplant failure during rejection episodes
Formulations and methods are provided for improving the function, i.e. clinical outcome, of solid organ transplants. Lung transplantation is of particular...
US-9,763,898 Nutritional composition for promoting musculoskeletal health in patients with inflammatory bowel disease (IBD)
A nutritional composition promotes musculoskeletal health in patients with inflammatory bowel disease. The nutritional composition contains casein protein,...
US-9,763,897 Therapeutic astaxanthin and phospholipid composition and associated method
A dietary supplement includes comprising a therapeutic amount of astaxanthin derived from a synthetic or natural ester or diol, and at least one of a...
US-9,763,896 Induced expression of brain derived neurotrophic factor (BDNF) for treatment of neuromuscular,...
A method of treating a host of neuromuscular, neurodegenerative, developmental, autoimmune and metabolic diseases/disorders related to aging, such as traumatic...
US-9,763,895 Tincture for infusing flavonoids and methods of use
Methods and formulations for infusing bioavailable flavonoid tinctures into food, beverage, cosmetic or drug products with minimal or no effect on the alcohol...
US-9,763,894 Inflammation therapy
A method is provided for treating a patient in need of therapy for central nervous system inflammation comprising administering to that patient a...
US-9,763,893 Monopolymer multifunctional sequenced cast polyurethane matrix and production method
The invention relates to a monopolymer multifunctional sequenced cast polyurethane matrix produced simply and efficiently, by sequentially pouring various...
US-9,763,892 Immediate release phospholipid-coated therapeutic agent nanoparticles and related methods
Phospholipid-coated nanoparticles containing a therapeutic agent, compositions that include the nanoparticles, and methods for making and using the...
US-9,763,891 Therapeutic nanoparticles and methods of use thereof
Provided herein are therapeutic nanoparticles having a diameter of between 10 nm to 30 nm, and containing a polymer coating, and a nucleic acid containing a...
US-9,763,890 Bacterial ghosts as carrier and targeting vehicles
The invention concerns the use of bacterial ghosts as carrier and targeting vehicles for active substances.
US-9,763,889 Oral delivery system for hemoglobin based oxygen carriers
A process for making hemoglobin based oxygen carrier (HBOC) containing pharmaceutical composition suitable for oral delivery and the composition formed thereby...
US-9,763,888 Rapidly dispersible, fine-particle film-coating composition which is in powder form, is not prone to...
A rapidly dispersible, fine-particle film-coating composition which is in powder form and is not prone to segregation for coating pharmaceutical dosage forms,...
US-9,763,887 Mesalamine pharmaceutical composition with multiple dosage elements for reduced delivery variability
A mesalamine pharmaceutical composition with reduced delivery variability for delivery of mesalamine to the colon that includes multiple dosage elements, and...
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