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Patent # Description
US-9,771,407 Pharmaceutical preparation
Preparations including recombinant FSH (rFSH).
US-9,771,406 Peptidic dual GLP-1/glucagon receptor agonists derived from exendin-4
The present invention relates to dual GLP-1/glucagon receptor agonists or optionally trigonal GLP-1/glucagon/GIP receptor agonists and their medical use, for...
US-9,771,405 Nucleic acids encoding for chimeric natriuretic polypeptides with unique pharmacologic profiles
This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide...
US-9,771,404 Multi-level specific targeting of cancer cells
A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R.alpha.2 binding ligand; at least one effector...
US-9,771,403 Methods and compositions for treating hemophilia
Disclosed herein are methods and compositions for insertion of transgene sequences encoding proteins involved in clotting into the genome of a cell for treating...
US-9,771,402 Fluorescent and colored proteins and methods for using them
The field of this invention relates to methods for combining genetic elements such that the activity of one of the elements provides a means for identifying,...
US-9,771,401 Green fluorescent protein (GFP) peptides from Rhacostoma
The present technology is directed to the nucleic acid molecule encoding novel fluorescent proteins, in particular, green fluorescent proteins (GFPs), such as...
US-9,771,400 Photoactive silk protein and fabrication of silk protein structures using photolithography
A natural protein, specifically silk fibroin or sericin, is chemically modified such that it can be rendered photoactive, but which otherwise has similar...
US-9,771,399 Immunogenic bacterial vesicles with outer membrane proteins
Knockout of the meningococcal mltA homolog gives bacteria that spontaneously release vesicles that are rich in immunogenic outer membrane proteins and that can...
US-9,771,398 Method of protein extraction from cells
Methods for producing a protein extract from cells, such as cells containing viral proteins, are provided. In general terms, the methods involve: increasing the...
US-9,771,397 HPV chimaeric particle
This invention relates to a chimaeric human papillomavirus (HPV) virus like particle (VLP) having a diameter of about 30 nm. The invention further relates to...
US-9,771,396 Phase transition biopolymers and methods of use
The present disclosure describes environmentally responsive polypeptides capable of displaying stimuli-triggered conformational changes in a reversible or...
US-9,771,395 Enhanced influenza hemagglutinin binders
Designed polypeptides having the amino acid sequence of SEQ ID NQ: 1 are described that bind with high affinity and selectivity to the influenza hemagglutinin...
US-9,771,394 Antimicrobial polymyxins for treatment of bacterial infections
The present invention provides antimicrobial polymyxin compounds of the following formula I: ##STR00001## or pharmaceutically acceptable salts, hydrates, or...
US-9,771,393 Bioactive peptides having insecticide activity
Disclosed are novel bioactive peptides derived as antagonists to a fire ant receptor for a pheromone biosynthesis-activating neuropeptide/pyrokinin...
US-9,771,392 Compounds which inhibit neuronal exocytosis
Compounds of general formula (I): R.sub.1-W.sub.n-X.sub.m-AA.sub.1-AA.sub.2-AA.sub.3-AA.sub.4-AA.sub.5-AA.s- ...
US-9,771,391 Process for preparing tubulysins
The invention described herein pertains to processes for preparing tubulysins and derivatives thereof. The invention described herein also pertains to processes...
US-9,771,390 Process for the preparation of regadenoson
The present invention provides novel processes for the preparation of regadenoson having the formula (I). In some embodiments, the intermediates for the...
US-9,771,389 Tylosin derivatives and method for preparation thereof
The present invention relates to new macrolide derivatives, in particular new tylosin derivatives of the formula (IIa), a pharmaceutical or veterinary...
US-9,771,388 Metal complexes
The present invention provides novel metal complexes, methods of making, and methods of using the same.
US-9,771,387 Platinum compounds having a heterocycle ligand, nanoparticles, and uses thereof
The present disclosure relates to novel platinum compositions having a heterocycle ligand and nanoparticles and methods using such compositions, e.g. for...
US-9,771,386 Z-selective ring-closing metathesis reactions
The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.
US-9,771,385 Oxidized lipids
The present invention is directed to oxidized lipids and pharmaceutical compositions comprising the same. The present invention is also directed to methods of...
US-9,771,384 Fluorochemical surface treating agent and article treated therewith
A fluorochemical surface treating agent comprising a hydrolyzable group-containing silane modified with a fluorooxyalkylene-containing polymer and/or a partial...
US-9,771,383 Modified opioids containing silicon
A modified opioid is provided comprising modified morphine molecules, wherein for each morphine molecule, one or more carbon atoms are replaced with silicon...
US-9,771,382 Beta-lactamase inhibitors
Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit...
US-9,771,381 Derivatives of 1-amino-2-cyclobutylethylboronic acid
The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds...
US-9,771,380 Gold nanoparticles and methods of making and using gold nanoparticles
Disclosed herein are embodiments of gold nanoparticles and methods of making and using the gold nanoparticles. The disclosed gold nanoparticles have core sizes...
US-9,771,379 N-(2-(2-amino-6-substituted-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]OXAZIN-8a- (8H)-yl)-thiazol-4-yl) amides
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have...
US-9,771,378 Fused morpholinopyrimidines and methods of use thereof
The present disclosure relates to Fused Morpholinopyrimidines, pharmaceutical compositions comprising an effective amount of a Fused Morpholinopyrimidine and...
US-9,771,377 Synthesis of FR901464 and analogs with antitumor activity
The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an...
US-9,771,375 Indazole compounds useful as ketohexokinase inhibitors
The present invention is directed to substituted indazole compounds, pharmaceutical compositions of these compounds and methods of use thereof. The compounds of...
US-9,771,374 Benzimidazole retinoic acid receptor-related orphan receptor modulators and uses thereof
Provided herein are compounds of the formulas (I) and (II): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those...
US-9,771,373 Condensed cyclic compound and organic light-emitting device including the same
A condensed cyclic compound represented by one of Formulae 1A to 1C, wherein Formulae 1A to 1C are disclosed in the detailed description.
US-9,771,372 Compounds useful as S100-inhibitors
A compound of formula (I) or a pharmaceutically acceptable salt thereof and a pharmaceutical composition comprising the compound. The compound is an inhibitor...
US-9,771,371 Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
Provided herein are Heteroaryl Compounds having the following structure: ##STR00001## wherein R.sup.1-R.sup.4 are as defined herein, compositions comprising an...
US-9,771,370 Compounds for the inhibition of indoleamine-2,3-dioxygenase
The present invention relates to compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of IDO, and for the treatment of...
US-9,771,369 Compounds and methods for kinase modulation, and indications therefor
Compounds active on c-kit protein kinases or mutant c-kit protein kinases having any mutations are described, wherein the compounds are of Formula (I): ...
US-9,771,368 .sup.18F-labelled folates
The present invention is directed towards new .sup.18F-folate radiopharmaceuticals, wherein the fluorine-18 is covalently linked to the aminobenzoyl moiety,...
US-9,771,367 Method for preparation of alkylated or fluoro, chloro and fluorochloro alkylated compounds by heterogeneous...
The invention discloses a method for preparation of alkylated or fluoro, chloro and fluorochloro alkylated compounds by a heterogeneous Pt/C-catalyzed...
US-9,771,366 Substituted tetrahydropyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine-2-carboxamides as RSK inhibitors
Described herein are carboxamide derivatives of Formula (II) that are useful as inhibitors of p90 ribosomal S6 kinase (RSK), pharmaceutical compositions...
US-9,771,365 Spiroheterocyclic N-oxypiperidines as pesticides
A compound of the formula I ##STR00001## wherein the substituents are as defined in claim 1, are useful as a pesticides.
US-9,771,364 Process for preparation of (2S,5R)-6-sulphooxy-7-oxo-2-[((3R)-piperidine-3-carbonyl)-hydrazinocarbon- ...
A process for preparation of a compound of Formula (I) is disclosed. ##STR00001##
US-9,771,363 Heterocyclic compounds and uses thereof
Provided herein are heterocyclic compounds of Formula (I), pharmaceutical compositions containing such a compound and their therapeutic uses, methods for their...
US-9,771,362 [1,2,4]triazolo[1,5-a]pyridine and [1,2,4]triazolo[1,5-c]pyrimidine compounds and their use
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain triazolo compounds (referred to herein as TAZ...
US-9,771,361 Inhibitors of influenza viruses replication
Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula: ...
US-9,771,360 Cyano-substituted imidazo[1,2-A]pyridinecarboxamides and their use
The present application relates to novel substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or...
US-9,771,359 Substituted oxazole- and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II
The invention relates to oxazole and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing...
US-9,771,358 Dihydropyrimidine compounds and their application in pharmaceuticals
Provided herein are dihydropyrimidine compounds and their pharmaceutical applications, especially for use in treating and preventing HBV diseases. Specifically,...
US-9,771,357 ALXR agonist compound
The present invention provides a compound having ALXR agonist activity. Specifically, the invention provides a compound having ALXR agonist activity represented...
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