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Patent # Description
US-9,777,330 mPCR methods for analyzing repeat sequences
Methods are provided for determining the methylation status of GC-rich templates. The methods include use of GC reference standards that allow simultaneous...
US-9,777,329 Non-invasive fetal genetic screening by digital analysis
The present methods are exemplified by a process in which maternal blood containing fetal DNA is diluted to a nominal value of approximately 0.5 genome...
US-9,777,328 Non-invasive fetal genetic screening by digital analysis
The present methods are exemplified by a process in which maternal blood containing fetal DNA is diluted to a nominal value of approximately 0.5 genome...
US-9,777,327 DNA conformation (loop structures) in normal and abnormal gene expression
Method of detection or diagnosis of abnormal gene expression in an individual comprising determining in a sample from the individual the presence or absence of...
US-9,777,326 Method of sequencing nucleic acid colonies formed on a patterned surface by re-seeding
A method of sequencing nucleic acids, which can include steps of (a) providing a substrate comprising a surface having a repeating pattern of features, wherein...
US-9,777,325 Fluidic system for reagent delivery to a flow cell
A fluidic system that includes a reagent manifold comprising a plurality of channels configured for fluid communication between a reagent cartridge and an inlet...
US-9,777,324 Method for high-throughput AFLP-based polymorphism detection
The invention relates to a method for the high throughput discovery, detection and genotyping of one or more genetic markers in one or more samples, comprising...
US-9,777,323 Assembly and method for analyzing nucleic acid sequences by way of so-called sequencing-by-synthesis
An assembly and a method are disclosed for analyzing nucleic acid sequences by way of so-called sequencing-by-synthesis. According to an embodiment of the...
US-9,777,322 Sequence based genotyping based on oligonucleotide ligation assays
The invention relates to a method for the detection of a target nucleotide sequence in a sample based on an oligonucleotide ligation assay wherein probes are...
US-9,777,321 Single molecule detection system and methods
Embodiments encompass a single-molecule detection system and methods of using the detection system to detect an object. Further, embodiments encompass a...
US-9,777,320 Molecular adaptors for dye conjugates
In various embodiments, the present invention provides fluorescent dyes that are linked to another species through an adaptor moiety. In an exemplary...
US-9,777,319 Method for isothermal DNA amplification starting from an RNA template
A method of amplifying RNA template is provided. The method comprises reverse-transcribing a ribonucleic acid (RNA) template to form a cDNA using a first...
US-9,777,318 Systems and methods for monitoring the amplification of DNA
A system and method for amplifying and detecting nucleic acids are disclosed. In one embodiment, the system includes: a microfluidic device comprising a channel...
US-9,777,317 Microfluidic PCR device
A microfluidic device (1000-1005), comprising: a semiconductor body (2) having a first side (2a) and a second side (2b) opposite to one another, and housing, at...
US-9,777,316 Amplification of complex nucleic acids
What is described is a method for quantitative and qualitative analysis of complex template nucleic acids to be analyzed. The method comprises the...
US-9,777,315 Exonuclease enabled proximity extension assays
The present invention relates to a proximity probe based detection assay ("proximity assay") for an analyte in a sample, specifically a proximity probe...
US-9,777,314 Analysis of heterogeneous nucleic acid samples
Methods for capturing and characterizing low frequency nucleic acid molecules indicative of diseases such as cancer (e.g. adenomas or early stage cancers) are...
US-9,777,313 Silver nanocluster probe and target polynucleotide detection method using same, and silver nanocluster probe...
The present invention provides a silver nanocluster probe which comprises a silver nanoparticle binding region and a specific nucleotide sequence region that...
US-9,777,312 Dual polarity analysis of nucleic acids
This invention provides methods for characterizing the amounts of nucleic acids, including plus/minus determinations, the use of different constructs, the use...
US-9,777,311 Synthetic Oplophorus luciferases with enhanced light output
A polynucleotide encoding a modified luciferase polypeptide. The modified luciferase polypeptide has at least 60% amino acid sequence identity to a wild-type...
US-9,777,310 Leukocyte esterase detection from throat swab
The present invention relates to the field of infectious diseases. The invention specifically relates to the diagnostic test for acute bacterial pharyngitis....
US-9,777,309 High throughput assay for monitoring AMP production and aminoacyl-tRNA synthetase activity
A method of conducting an enzymatic reaction assay involving adenosine 5'-monophosphate (AMP) comprising the steps of reacting one or more compounds and...
US-9,777,308 Device for analyzing the effect of a gaseous medium on a biological test system using an extracellular...
The invention relates to a method for analyzing the effect of a gaseous medium on a biological test system using an extracellular metabolization system. The...
US-9,777,307 Heterocyclic nitrogen containing polymer coated analyte monitoring device and methods of use
The present invention is directed to membranes composed of heterocyclic nitrogen groups, such as vinylpyridine and to electrochemical sensors equipped with such...
US-9,777,306 Modified arsenite oxidase and a biosensor for detecting arsenite
The present invention provides an arsenite oxidase enzyme modified to prevent translocation by modification of a translocation signal sequence. A microorganism...
US-9,777,305 Method for the assembly of a polynucleic acid sequence
Provided herein are methods for the assembly of a polynucleic acid sequence that is at least partially carried out on a microfluidic device; methods for the...
US-9,777,304 Enzymes for starch processing
The present invention relates to polypeptides comprising a carbohydrate-binding module amino acid sequence and an alpha-amylase amino acid sequence as well as...
US-9,777,303 Systems and methods for producing a sugar stream
An improved dry grind system and method for producing a sugar stream from grains or similar carbohydrate sources and/or residues, such as for biofuel...
US-9,777,302 Methods, reagents and cells for biosynthesizing compounds
This document describes biochemical pathways for producing 5-hydroxypentanoate methyl ester and pentanoic acid pentyl ester using one or more of a fatty acid...
US-9,777,301 Method for producing optically active amine compounds by deracemization
Disclosed are methods for producing optically active amino acids and amines. According to the methods, .alpha.-keto acids are generated as reaction...
US-9,777,300 Hybrid organic-inorganic system for producing biofuels
The present invention provides for a system for converting CO.sub.2 and H.sub.2 to one or more biologically derived compounds. In some embodiments, the system...
US-9,777,299 Oxidoreductase reaction control and use thereof
The present invention is intended to prove a technique useful for controlling the reaction of oxidoreductase, and to provide a reaction system allowing...
US-9,777,298 Use of Monascus in organic acid production
The present invention provides tools and methods for producing organic acids using strains of Monascus which are tolerant to high organic acid concentrations at...
US-9,777,297 Microbial production of n-butyraldehyde
Microorganisms and methods of producing n-butyraldehyde with enhanced yields are presented in which a microorganism is engineered to enhance the conversion of a...
US-9,777,296 Method for producing bioproducts using hydrolyzed organic wastes of fermentation
Provided is a method for producing bioproducts, including the steps of: culturing a first microorganism to produce bioalcohol; hydrolyzing the first...
US-9,777,295 Methods for biosynthesis of isobutene
The document provides methods for biosynthesizing isobutene using one or more isolated enzymes such as one or more of an enoyl-CoA dehydratase, a ...
US-9,777,294 Compositions and methods for producing isoprene free of C5 hydrocarbons under decoupling conditions and/or safe...
The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions...
US-9,777,293 Method for producing beta-santalene
The present invention provides a method of producing .beta.-santalene, said method comprising contacting at least one polypeptide with farnesyl pyrophosphate...
US-9,777,292 Methods for treating biosolids sludge with cavitation
Described herein are processes for increasing biogas yield and reducing volatile solids in biosolids sludge. The biosolids sludge is passed through a controlled...
US-9,777,291 Recombinant adeno-associated vectors for targeted treatment
Novel adeno-associated virus (AAV) vectors in nucleotide and amino acid forms and uses thereof are provided. The isolates show specific tropism for certain...
US-9,777,290 Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences
The present invention relates to expression vectors for the heterologous expression of a nucleic acid sequence of interest in mammalian cells, the vectors...
US-9,777,289 Insect inhibitory toxin family active against hemipteran and/or lepidopteran insects
The present invention discloses a genus of insect inhibitory proteins that exhibit properties directed to controlling Lepidopteran and/or Hemipteran crop pests,...
US-9,777,288 Compositions and methods for controlling leptinotarsa
Disclosed herein are methods of controlling insect pests, in particular Leptinotarsa spp. which infest crop plants, and methods of providing plants resistant to...
US-9,777,287 Nucleotide sequences and corresponding polypeptides conferring modified phenotype characteristics in plants
Methods and materials for modulating low-nitrogen tolerance levels in plants are disclosed. For example, nucleic acids encoding low nitrogen ...
US-9,777,286 Zea mays metallothionein-like regulatory elements and uses thereof
Provided are constructs and methods for expressing a transgene in plant cells and/or plant tissues using Zea mays metallothionein-like gene regulatory elements.
US-9,777,285 Promoter, promoter control elements, and combinations, and uses thereof
The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements,...
US-9,777,284 Modified FRT recombination site libraries and methods of use
Methods and compositions using populations of randomized modified FRT recombination sites to identify, isolate and/or characterize modified FRT recombination...
US-9,777,283 Engineering of hydrocarbon metabolism in yeast
The present invention relates to the development of genetically engineered yeasts that can produce hydrocarbons in a controllable and economic fashion. More...
US-9,777,282 Corynebacterium microorganism with improved ability to produce L-lysine and method for producing L-lysine using...
A microorganism of the genus Corynebacterium with an improved ability to produce L-lysine in which a septum formation initiator protein is inactivated and a...
US-9,777,281 Methods and compositions for regulation of transgene expression
Nucleases and methods of using these nucleases for expressing a transgene from a safe harbor locus in a secretory tissue, and clones and animals derived therefrom.
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