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Patent # Description
US-9,782,489 MetAP-2 inhibitor polymersomes for therapeutic administration
The present invention provides methods to treating inflammation related disease and disorders such as an autoimmune disease and autoimmune related uveitis by...
US-9,782,488 Oligomer-beta blocker conjugates
The invention provides water-soluble oligomer-beta blocker drug conjugates. A drug conjugate of the invention can be administered by any of a number of...
US-9,782,487 Glycerophospholipids for the improvement of cognitive functions
The invention described herein provides a preparation comprising a non-mammalian derived mixture of serine glycerophospholipid conjugates with a specific...
US-9,782,486 Albumin conjugated temperature and pH-sensitive multi-block copolymer, a method of preparation thereof and drug...
The present invention relates to a conjugate of albumin and a temperature- and pH-sensitive multi-block copolymer, a method of preparation thereof, and a...
US-9,782,485 Topical gel compositions including polycaprolactone polymer and methods for enhancing the topical application...
A composition comprising: a benefit agent; at least one polymer including a polycaprolactone polymer; at least one lower alcohol; and at least one co-solvent;...
US-9,782,484 Method for producing a composite organic compound powder for medical use
The purpose of present invention is to provide a medicine which has low contamination with a fine-pulverizing medium, is safe and has improved bioavailability....
US-9,782,483 Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy
The invention refers to the use of a sigma ligand, preferably a sigma ligand of formula (I), to prevent or treat emesis induced by a chemotherapeutic agent or...
US-9,782,482 Transdermal device for the controlled administration of at least one active ingredient to a patient
A transdermal device (1) comprising at least one substrate (2) arranged to be applied against the dermal surface or the mucous membrane. The at least one active...
US-9,782,481 Nanoparticle delivery system for targeted anti-obesity treatment
A magnetic nanoparticles including a TRPV1 agonist, as well as methods of preparation and use, are described herein. A magnetically responsive pharmaceutical...
US-9,782,480 Stable aqueous formulations of adalimumab
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
US-9,782,479 Stable aqueous formulations of adalimumab
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these...
US-9,782,478 Prostate-specific membrane antigen binding proteins and related compositions and methods
The present invention relates to mono-specific and multi-specific polypeptide therapeutics that specifically target cells expressing prostate-specific membrane...
US-9,782,477 Fraction I-IV-1 precipitation of immunoglobins from plasma
Among other aspects, the present invention provides methods for the manufacture of blood protein compositions from pooled plasma. In one embodiment, the...
US-9,782,476 Human iNKT cell activation using glycolipids with altered glycosyl groups
Glycosphingolipids (GSLs) bearing .alpha.-glucose (.alpha.-Glc) that preferentially stimulate human invariant NKT (iNKT) cells are provided. GSLs with...
US-9,782,475 Method of treating food allergies by administering a nanoparticle comprising heparin and chitosan encapsulating...
Provided are nanoparticles comprising heparin, chitosan, and at least one immunomodulatory agent, e.g. a cytokine. The cytokine can be selected from the group...
US-9,782,474 Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
Herpes Simplex Virus-2 (HSV-2) infection is a major health concern. Highly effective vaccines and immunogenic compositions against HSV-2, which can be used...
US-9,782,473 Compositions and methods for the treatment or prevention of human immunodeficiency virus infection
Disclosed are yeast-based immunotherapeutic compositions, human immunodeficiency virus (HIV) antigens, and fusion proteins for the treatment and/or prevention...
US-9,782,472 Therapeutic compositions and methods for treating HIV including identification and manipulation of particular...
Therapeutic compositions and methods for treating HIV including identification and manipulation of particular domains associated with immunogenicity.
US-9,782,471 EV71 virus-like particles and preparation method and application thereof
The present invention provides EV71 virus-like particles and a preparation method and application thereof. The method comprises: connecting a P1 protein gene...
US-9,782,470 Method of obtaining thermostable dried vaccine formulations
This present invention relates to compositions and methods for stabilizing a dried vaccine formulations. In particular, the invention provides a method for...
US-9,782,469 Anti-inflammatory, skin-regenerative, whitening, antioxidant, or wound-healing composition containing culture...
The present invention relates to an anti-inflammatory, skin-regenerative, whitening, antioxidant, or wound-healing composition containing a culture medium of...
US-9,782,468 Purification of polysaccharide protein conjugates
The invention describes a method of purifying polysaccharide protein conjugates using mixed mode chromatography. The method involves contacting a crude...
US-9,782,467 Capsular polysaccharide solubilisation and combination vaccines
Precipitated bacterial capsular polysaccharides can be efficiently re-solubilized using alcohols as solvents. The invention provides a process for purifying a...
US-9,782,466 Capsular polysaccharide solubilisation and combination vaccines
Precipitated bacterial capsular polysaccharides can be efficiently re-solubilized using alcohols as solvents. The invention provides a process for purifying a...
US-9,782,465 Serologic correlates of protection against Bacillus anthracis infection
Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to Bacillus...
US-9,782,464 Methods and compositions for inhibiting diseases of the central nervous system
Methods and compositions for treating central nervous system diseases and disorders are disclosed.
US-9,782,463 Method for allogeneic cell therapy
A method of manipulating allogeneic cells for use in allogeneic cell therapy providing a composition of highly activated allogeneic T-cells which are infused...
US-9,782,462 Modified polynucleotides for the production of proteins associated with human disease
The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
US-9,782,461 Human coagulation factor light chain protein and use of the same
In the invention, the minimum inhibitory concentrations of human coagulation factor light-chain proteins against different Gram-negative bacteria are detected...
US-9,782,460 Treatment of diseases related to hyperactivity of the complement system
Raising the level of Factor I above physiological levels can be used to treat diseases in which the underlying pathology is linked to overactivity of the...
US-9,782,459 Eosinophil peroxidase compositions and methods of their use
Eosinophil peroxidase compositions and methods of their use for killing and/or inhibiting the growth of susceptible microorganisms are provided. The...
US-9,782,458 Composition for tissue/cell repair
The composition for tissue/cell repair facilitates healing of damaged tissues, promoting tissue and cell growth, protecting cells and tissues, and reducing scar...
US-9,782,457 Flowable formulations for tissue repair and regeneration
A formulation and method are provided for treating wounds by promoting healing and tissue repair and/or regeneration therein. The formulation is a topically...
US-9,782,455 Solid phase synthesis of h(Gly2)GLP-2
The present invention relates to a method of preparing a peptide comprising the amino acid sequence ...
US-9,782,454 Highly active polypeptides and methods of making and using the same
This invention relates to novel compositions comprising analogs of naturally occurring polypeptides, wherein the analog comprises an .alpha.-amino acid and at...
US-9,782,453 Use of hepcidin as a regulator of iron homeostasis
The invention concerns the use of hepcidin for the diagnosis and therapy of disorders of iron homeostasis. Hepcidin can be used in the treatment of disorders...
US-9,782,452 Methods for stimulating hematopoietic recovery by inhibiting TGF.beta. signaling
This disclosure demonstrates that blockade of TGF.beta. signaling after a hematopoietic stress (e.g., chemotherapy, transplantation, and infection) accelerates...
US-9,782,451 Romidepsin formulations and uses thereof
Provided herein are liquid concentrate formulations of romidepsin. Also provided are methods for producing these formulations and uses thereof. In one...
US-9,782,450 Composition comprising scirpusin A and scirpusin B and anti-obesity potential thereof
Disclosed are methods of managing obesity and hypercholesterolemia using a composition of matter comprising the ethyl acetate fraction of the extract of Cyperus...
US-9,782,449 Method for the treatment of addiction to tobacco
A method for the treatment of addiction to tobacco includes the stages of i) interviewing and training of a tobacco user (patient) and an accompanying person...
US-9,782,448 Methods and compositions for treating skin
A method for treating intact irritated or inflamed skin with a composition comprising at least one Histamine Receptor pathway inhibitor; at least one...
US-9,782,447 Method to prepare Hirsutella sinensis polysaccharides possessing protective activities on fatty liver disease
The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides can reduce liver size, weight and the...
US-9,782,446 Lactobacillus plantarum isolated from leaves of Camellia sinensis
Disclosed are novel Lactobacillus plantarum strains as well as a composition containing the novel Lactobacillus plantarum strains or a culture thereof.
US-9,782,445 Microbiota restoration therapy (MRT), compositions and methods of manufacture
Microbiota restoration therapy compositions and methods for manufacturing, processing, and/or delivering microbiota restoration therapy compositions are...
US-9,782,444 Preparation and use of fish skin fermentation liquid obtained by fermenting fish skin with Aspergillus
The present invention relates to a method for fermenting fish skin by using Aspergillus. Also provided is a use of the fermentation liquid obtained by...
US-9,782,443 Preparing tooth-like structure using stem cell
The usage of a stem cell in preparation of a tooth-like structure is provided. And a culture medium, a method for preparing an epithelial-like cell, a kit for...
US-9,782,442 Core-shell capsules for encapsulation of particles, colloids, and cells
Methods for preparing capsules, such as micro- and/or nanocapsules from all-aqueous emulsions are described herein. The method includes mixing, combining, or...
US-9,782,441 Stromal cell therapy in treatment of radiation injury
Methods are provided for treating, mitigating or protecting from radiation-induced injury using bone marrow stromal cells expanded in culture, adipose-tissue...
US-9,782,440 Methods for treating genitourinary disorders
One aspect of the present disclosure can include a therapeutic composition useful for treatment of a genitourinary disorder. The composition can be derived from...
US-9,782,439 Cell sheet containing mesenchymal stem cells
Mesenchymal stem cells are pluripotent cells capable of differentiating into myocardial and vascular endothelial cells. The present invention demonstrates that...
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