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Patent # Description
US-9,782,438 Method of promoting hair growth by administration of BFGF
Disclosed are a method of promoting hair growth or preventing hair loss in a mammal. In one aspect, the method includes administering interdermally or...
US-9,782,437 Methods and compositions for targeted cleavage and recombination
Disclosed herein are methods and compositions for targeted cleavage of a genomic sequence, targeted alteration of a genomic sequence, and targeted recombination...
US-9,782,436 Flowable tissue matrices
Disclosed herein are flowable tissue matrix compositions comprising small pieces of partially or completely decellularized tissue suspended in a gelatinized...
US-9,782,435 Production of moldable bone substitute
Composites and methods of producing a mouldable bone substitute are described. A scaffold for bone growth comprises nanocrystalline hydroxyapatite (HA), a...
US-9,782,434 Methods of treating or preventing inflammation and hypersensitivity with oxidative reductive potential water...
Provided is a method for preventing or treating inflammation and associated states (e.g. infection, hypersensitivity, pain) by administering a therapeutically...
US-9,782,433 Co-network of high and low molecular weight 3-arm star cyanoacrylate-telechelic polyisobutylene and 2-octyl...
In one or more embodiments, the present invention relates to a substantially homogeneous miscible liquid adhesive composition comprising a relatively high...
US-9,782,432 Polymers and methods thereof for wound healing
Certain embodiments of the invention provide a copolymer having a backbone, wherein the backbone comprises a) one or more units that comprise a group that will...
US-9,782,431 Method to prepare hirsutella sinensis polysaccharides possessing anti-obesity properties and uses thereof
The present invention provides a method to prepare polysaccharides from Hirsutella sinensis. The prepared polysaccharides reduce body weight and fat...
US-9,782,430 Resorbable oxidized cellulose embolization solution
A method for forming an embolism within a blood vessel is disclosed. The method includes including: implanting an oxidized cellulose embolization solution into...
US-9,782,429 Formulation having mobilizing activity
The present innovation relates to a novel formulation capable of increasing the amount of stem cells and progenitor cells in circulation in the peripheral blood...
US-9,782,428 Method for generation of broadly neutralizing anti-pathogen antibodies
Methods and composition for potentiating germinal centers are disclosed herein. The methods include potentiating germinal centers to enhance antibody production...
US-9,782,427 Methods for treating cancer using TOR kinase inhibitor combination therapy
Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a TOR kinase inhibitor having the following...
US-9,782,426 Anti-viral therapeutic composition
This invention relates to a topical composition for prevention and treatment of viral infections.
US-9,782,425 Treatment of papulopustular rosacea with ivermectin
Methods and compositions for safe and effective treatment of papulopustular rosacea in a subject are described. The methods involve topically applying to an...
US-9,782,424 Synergistic combination comprising avermectins and a NSAID for tumor inhibition
The present invention includes a composition comprising an effective amount of an avermectin compound, and an effective amount of an imidazole antifungal...
US-9,782,423 Antibiotic compositions comprising an antibiotic agent and cysteamine
The invention relates to products comprising an antibiotic agent and a second agent being a dispersant or an anti-adhesive agent, in particular a mucolytic...
US-9,782,422 Treatment of conditions associated with mycotoxin exposure
We describe a composition comprising a non-digestible oligosaccharide for the treatment, prevention or alleviation of a trichothecene mycotoxin exposure...
US-9,782,421 Neridronic acid molecular complex for treating complex regional pain syndrome
Complexes of neridronic acid, in an acid or a salt form, with amino acids, can be used to treat or alleviate pain or related conditions, such as complex...
US-9,782,420 Method for treating eye diseases
The present invention provides a pharmaceutical composition for removing drusen, suppressing formation of drusen, and/or treating and/or preventing age-related...
US-9,782,419 Transdermal contraceptive hormones delivery
Dosing regimen for transdermal delivery of hormones comprising a variable treatment cycle and a variable rest interval.
US-9,782,418 Rationale-based design of a targeted therapy for cancer
The methods, compositions, and kits of the invention are related to the discovery that lestaurtinib reduces levels and pathway activity of an SPOP substrate....
US-9,782,417 Methods of increasing satellite cell proliferation with kinase inhibitors
The invention provides methods for inducing, enhancing or increasing satellite cell proliferation, and an assay for screening for a candidate compound for...
US-9,782,416 Pharmaceutical formulations of potassium ATP channel openers and uses thereof
Provided are immediate or prolonged administration of certain potassium ATP (K.sub.ATP) channel openers to a subject to achieve novel pharmacodynamic,...
US-9,782,415 Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors
Compounds of Formula I: ##STR00001## and salts thereof in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, X, Y and n have the meanings given in the specification,...
US-9,782,414 Crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-A]pyri- ...
A novel crystalline form of (S)--N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyri- midin-3-yl)-3-hydroxypyrrolidine-1-carboxamide,...
US-9,782,413 Composition for treatment of essential thrombocythemia
The present invention relates to a novel pharmaceutical composition free of gastric coating comprising anagrelide hydrochloride in combination with a non-pH...
US-9,782,412 Preventive and/or therapeutic agent of immune disease
Provided is a preventive and/or therapeutic agent for immune diseases containing a compound having a BTK inhibitory activity or a salt thereof, as an active...
US-9,782,411 {4-[5-(3-chloro-phenoxy)-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-phenox- y}-acetic acid for use in the...
{4-[5-(3-chloro-phenoxy)-oxazolo[5,4-d]pyrimidin-2-yl]-2,6-dimethyl-pheno- xy}-acetic acid or a pharmaceutically acceptable salt thereof for use in the...
US-9,782,410 Fluorocyclopentenylcytosine methods of use
The disclosed subject matter provides methods using and kits comprising a compound of formula (I) ##STR00001## or a hydrate, a solvate, or a pharmaceutically...
US-9,782,409 Treatment of cancer and benign proliferative disorders
Disclosed herein are compositions comprising lopinavir alone or in combination with ritonavir for use as a medicament in the treatment of cancer or benign...
US-9,782,408 Modulators of cystic fibrosis transmembrane conductance regulator
The present invention features a compound of formula I: ##STR00001## or a pharmaceutically acceptable salt thereof, where R.sub.1, R.sub.2, R.sub.3, W, X, Y,...
US-9,782,407 Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
The present invention provides a method for treating or preventing a condition or disease in a human or an animal subject wherein the condition or disease is...
US-9,782,406 Kinase inhibitor and method for treatment of related diseases
Disclosed is a compound of (aminophenylamino) pyrimidyl benzamides and a synthesis method thereof. The compound has Btk-inhibition activity and can be used to...
US-9,782,405 Heteroaryl pyridone and aza-pyrodine compounds
Heteroaryl pyridone and aza-pyridone compounds are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for...
US-9,782,404 Methods of treating disease-induced ataxia and non-ataxic imbalance
Methods for treatment of disease-induced ataxia and non-ataxic imbalance are disclosed. The methods involve treating a patient with a compound having nicotinic...
US-9,782,403 Treating sexual desire disorders with flibanserin
The invention relates to the use of fibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.
US-9,782,402 Injectable composition comprising buprenorphine
The present invention is directed to a buprenorphine sustained release delivery system capable of delivering buprenorphine, a metabolite, or a prodrug thereof...
US-9,782,401 Method of isolating phenanthroindolizidine alkaloids from Tylophora atrofolliculata with HIF-1 inhibitory...
A method of isolating at least one phenanthroindolizidine alkaloid, in particular with HIF-1 inhibitory activity, from Tylophora atrofolliculata is used to...
US-9,782,400 Oncogenic ROS1 and ALK kinase inhibitor
A compound suitable for treating cancer, in particular NSCLC, inhibits activity of oncogenic ROS1 kinase and ALK kinase. The compound has certain structural...
US-9,782,399 Pharmaceutical compositions which inhibit FKBP52-mediated regulation of androgen receptor function and methods...
Pharmaceutical compositions that bind to a predicted FK506 Binding Protein 52 (FKBP52) interaction surface on the androgen receptor hormone binding domain,...
US-9,782,398 Pharmaceutical compositions comprising an antipsychotic drug and a VMAT2 inhibitor and uses thereof
New methods of treating schizophrenia and schizoaffective disorder by administration of pharmaceutical compositions comprising an antipsychotic compound and a...
US-9,782,397 Treatment of corneal neovascularization
There is provided inter alia a compound which is an NK-1 receptor antagonist for use in the treatment or prevention of CNV. There is also provided a compound...
US-9,782,396 Alfentanil composition for the treatment of acute pain
There is provided pharmaceutical compositions for the treatment of pain e.g. short-term pain, which compositions comprise a mixture comprising: (a)...
US-9,782,395 2,4-thiazolidinedione derivatives in the treatment of central nervous system disorders
The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy) benzyl)thiazolidine-2,4-dione and novel stereoisomers of said compound for...
US-9,782,394 Inhibitors for ERG oncogene positive cancers
Alterations to the ERG gene are some of the most prominent genomic changes associated with many cancers including prostate cancer. Such cancer specific...
US-9,782,393 Pharmaceutical compositions and methods for treating cancer and biomarkers for drug screening
A pharmaceutical composition comprising sorafenib and GW5074. Said combination therapy inhibits cancer cell growth via c-Raf-PP2A-DAPK signaling transduction...
US-9,782,392 Azaindole derivative
A method for treating rheumatoid arthritis, multiple sclerosis, or a disease involving JAK3, including administering a compound of the formula (I) or a salt...
US-9,782,391 Substituted imidazo[1,2-a]pyridine compounds as tropomyosin receptor kinase a (TrkA) inhibitors
The present application relates to a series of substituted imidazo[1,2-a]pyridine compounds of formula (I), ##STR00001## pharmaceutically acceptable salts,...
US-9,782,390 Amidine substituted .beta.-lactam compounds, their preparation and use as antibacterial agents
The present invention relates to novel .beta.-lactam compounds, their preparation and use. In particular, this invention relates to novel .beta.-lactam...
US-9,782,389 Fungal mycobiome as probiotics, diagnostics and therapeutics
The present invention relates to methods of using fungal mycobiome as a means of treating and/or diagnosing diseases in a subject. In one embodiment, the...
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