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Patent # Description
US-9,783,847 Nucleic acid constructs and methods of use
The present invention provides oligonucleotide constructs, sets of such oligonucleotide constructs, and methods of using such oligonucleotide constructs to...
US-9,783,846 Detection of immune cells, in particular T cells through DNA-methylation analysis of the genes CCR6 and BLR1
The present invention relates to a method, in particular an in vitro method, for identifying certain immune cells of a mammal, comprising analyzing the...
US-9,783,845 Detection of target nucleic acid sequence by PTO cleavage and extension-dependent non-hybridization assay
The present invention relates to the detection of a target nucleic acid sequence by a PCE-NH (PTO Cleavage and Extension-Dependent Non-Hybridization) assay. The...
US-9,783,844 Method for amplifying nucleic acid and method for detecting amplified nucleic acid
An object of the present invention is to provide methods for amplifying and detecting a nucleic acid that allow efficient hybridization, and devices and kits...
US-9,783,843 Encoded self-assembling chemical libraries (esachel)
The invention provides a chemical compound comprising a chemical moiety (p) capable of performing a binding interaction with a target molecule, and an...
US-9,783,842 STR genotyping by differential hybridization
In a method of deducing the number of repeat units in a selected short tandem repeat (STR) in a genomic sample, at least a single stranded target DNA generated...
US-9,783,841 Detection of target nucleic acids in a cellular sample
Methods of assaying cells of a cellular sample for the presence of a target nucleic acid are provided. Aspects of the methods include evaluating a cellular...
US-9,783,840 Decalcification solution with preservation of RNA
The present invention is directed to methods of decalcification and tissue sample preparation that allows for the reproducible quantitative analysis of gene...
US-9,783,839 Automated container management device for microbial detection apparatus
The present invention is directed to a method and container locator means for moving a container among one or more work-flow stations within an apparatus. The...
US-9,783,838 PmST3 enzyme for chemoenzymatic synthesis of alpha-2-3-sialosides
The present invention provides novel methods for preparing glycosylated molecules such as oligosaccharides, glycolipids, and glycoproteins/peptides. Novel...
US-9,783,837 Catecholamine-based versatility film and a preparation method thereof
The present invention relates to a method for preparing a double-sided film containing the step of 5 forming a film in the interface between air and the mixture...
US-9,783,836 Thioesterases and cells for production of tailored oils
The invention features plant acyl-ACP thioesterase genes of the FatB class and proteins encoded by these genes. The genes are useful for constructing...
US-9,783,835 Method for producing a lipid in a fermentation process
The invention provides methods and systems for the production of lipid products from a gaseous substrate using a two stage fermentation process. The method...
US-9,783,834 Dicarboxylic acid fermentation process
The present invention relates to a process for producing a dicarboxylic acid, comprising fermenting a recombinant fungal cell in a suitable fermentation medium,...
US-9,783,833 Biocatalytic methods to convert cyclohexane oxidation process waste streams to useful products
The invention relates to methods for enriching monomer content in a cycloalkane oxidation process mixed organic waste stream. In particular, the methods involve...
US-9,783,832 Method for producing 2,3-butanediol using improved strains of Raoultella planticola
The invention relates to a method for producing 2,3-butanediol using improved strains of Raoultella planticola, and to novel mutant strains obtained by random...
US-9,783,831 Cyclodextrin glucanotransferase
The present invention relates to a novel cyclodextrin glucanotransferase (CGTase) enzyme which is obtainable from Clostridium saccharoperbutylacetonicum N1-4,...
US-9,783,830 Process for microbial fermentation of sugary substrates and use of the hydrogen in atomic, ionic or gaseous...
A process for microbial fermentation of sugary substrates may include inoculating hydrogen into a microorganism of a genera fungus or a bacterium present in...
US-9,783,829 Process for enhancing biogenic methane production from a carbonaceous material using gaseous nitrogen combinations
A nutrient combination for enhancing biogenic methane production from a carbonaceous material is described. The nutrient combination comprises a source of...
US-9,783,828 Recombinant cell, and method for producing isoprene
To provide a series of techniques capable of producing isoprene from syngas or the like. Provided is a recombinant cell prepared by introducing a nucleic acid...
US-9,783,827 DNA-binding proteins and uses thereof
Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also...
US-9,783,826 Recombinant virus production using mammalian cells in suspension
The invention generally provides methods for producing recombinant AAV viral particles using cells grown in suspension. The invention provides recombinant AAV...
US-9,783,825 Recombinant adeno-associated vectors for targeted treatment
Novel adeno-associated virus (AAV) vectors in nucleotide and amino acid forms and uses thereof are provided. The isolates show specific tropism for certain...
US-9,783,824 Self-complementary parvoviral vectors, and methods for making and using the same
The teachings herein are generally directed to a method of enhancing the genetic stability of parvovirus vectors. The stability of conventional ss or dsAAV...
US-9,783,823 Cytomegalovirus vectors enabling control of T cell targeting
CMV vectors comprising a heterologous protein antigen, an active UL131 protein (or an ortholog thereof), and an active UL128 protein (or an ortholog thereof)...
US-9,783,822 Gene therapy methods
The present invention generally provides improved gene therapy vectors, cell-based compositions, and methods of using the same in methods of gene therapy. The...
US-9,783,821 Cell for use in immunotherapy which contains modified nucleic acid construct encoding wilms tumor gene product...
A cell of the present invention contains a nucleic acid construct encoding a WT1 gene product or a fragment of the WT1 gene product. The nucleic acid construct...
US-9,783,820 Methods and compositions to enhance activity of Cry endotoxins
Methods and compositions for enhancing the resistance of plants to plant pests are provided. Chimeric pesticidal polypeptides and nucleic acid molecules...
US-9,783,819 Plant tolerance to low water, low nitrogen and cold II
Polynucleotides incorporated into nucleic acid constructs have been introduced into plants and were ectopically expressed. The encoded polypeptides of the...
US-9,783,818 Use of ADP/ATP transporter genes to increase nitrogen use efficiency and low nitrogen tolerance to a plant
Provided are methods of increasing nitrogen use efficiency, fertilizer use efficiency, yield, growth rate, vigor, biomass, oil content and/or abiotic stress...
US-9,783,817 Methods of expressing and detecting activity of expansin in plant cells
A method of expressing heterologous expansin in a plant cell is provided where a nucleic acid molecule encoding expansin is introduced into the plant cell and...
US-9,783,816 Collagen producing plants and methods of generating and using same
A method of producing collagen in a plant and plants producing collagen are provided. The method is effected by expressing in the plant at least one type of a...
US-9,783,815 Gene for increasing plant weight and method for using the same
A gene having novel functions is searched for, by which plant weight (that is, biomass level) can be increased and by which substance productivity can be...
US-9,783,814 Genetic reduction of male fertility in plants
Genetic male sterile plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and...
US-9,783,813 Methods for rapidly transforming monocots
The present invention provides methods for transforming monocot plants via a simple and rapid protocol, to obtain regenerated plants capable of being planted to...
US-9,783,812 Algal elongase 6
Provided herein are exemplary isolated nucleotide sequences encoding polypeptides having elongase activity, which utilize fatty acids as substrates.
US-9,783,811 Inducible gene expression composition for using eukaryotic pol-2 promoter-driven transcription in prokaryotes...
Eukaryotic protein-coding messenger RNAs and non-coding microRNAs are naturally transcribed by type II RNA polymerases (pol-2) but not prokaryotic RNA...
US-9,783,810 Plasmid vector, method for detecting gene promoter activity, and assay kit
According to one embodiment, a first gene encodes a reporter protein. The first gene is disposed at the downstream of the gene promoter. A second gene is...
US-9,783,809 Eukaryotic cell and method for producing glycolic acid
The present invention concerns a eukaryotic host selected from microorganisms, and a method for producing glycolic acid using said eukaryotic host cells,...
US-9,783,808 Ovarian cancer-specific aptamers and applications thereof
The present invention provides ovarian cancer-specific aptamers, which are selected in vitro using SELEX and a microfluidic chip system. The aptamers can also...
US-9,783,807 Nucleic acid molecule capable of binding to Salmonella and use thereof
A nucleic acid molecule utilizable for Salmonella detection is provided. The nucleic acid molecule which binds to Salmonella includes any of the following...
US-9,783,806 TMPRSS6 iRNA compositions and methods of use thereof
The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the TMPRSS6 gene, and methods of using such RNAi agents to inhibit expression...
US-9,783,805 Replication capable rAAV vectors encoding inhibitory siRNA and methods of their use
In some embodiments, an antiviral vector is provided. The antiviral vector includes a replication competent adeno-associated virus (AAV) and an inhibitory...
US-9,783,804 Compositions and methods for inhibition of nucleic acids function
The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions...
US-9,783,803 Inhibition of NEAT1 for treatment of solid tumors
The application relates to the field of cancer, particularly to the field of solid tumors. It was found that a particular long non-coding RNA (lncRNA), NEAT1,...
US-9,783,802 Interfering RNA molecules
The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand and...
US-9,783,801 Methods for creating and identifying functional RNA interference elements
The invention relates to the control of gene expression. Specifically, the invention provides compositions and methods for the production and use of recombinant...
US-9,783,800 Method for producing peptides having azole-derived skeleton
Object of the present invention is to develop an artificial synthesis system of various peptides having an azole derivative structure and develop a library of...
US-9,783,799 Enrichment of small nucleic acids
Provided herein is technology related to processing samples of nucleic acids and particularly, but not exclusively, to methods for enriching samples for small...
US-9,783,798 Site-specific incorporation of redox active amino acids into proteins
Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and...
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