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Patent # Description
US-9,814,731 Method for the induction of phase 2 related genes in a mammal comprising administering exemestane
In addition to its potent mechanism-dependent inhibition of estrogen biosynthesis, in accordance with the embodiments of the present invention, it has now been...
US-9,814,730 Pharmaceutical composition or group of compositions for inhibiting autocrine HCG production in adult human cells
A pharmaceutical composition for use as medicament that inhibits autocrine Human Chorionic Gonadotropin (HCG) production and thus carcinogenesis in adult human...
US-9,814,729 Nerve agent antidotes
The present invention includes compositions that are useful in treating, ameliorating, or preventing nerve agent poisoning. The present invention also includes...
US-9,814,728 Inhibition of DUX4 expression using bromodomain and extra-terminal domain protein inhibitors (BETi)
The use of BETi as a potential treatment for FSHD is provided. Specifically, the use of BETi, and particularly selective BETi for BRD4, are shown to inhibit...
US-9,814,727 Piperazine phenothiazine derivatives for treating spasticity
The present invention relates to piperazine phenothiazine derivatives useful as therapeutic agents for treating spasticity, particularly following an ischemia...
US-9,814,726 Composition for preventing or treating fatty liver diseases
The present invention relates to a pharmaceutical composition for preventing or treating fatty liver diseases, containing ...
US-9,814,725 Imidazopyridine compounds and uses thereof
This invention generally relates to substituted imidazopyridine compounds, particularly substituted 4-(imidazo[1,2-a]pyridin-2-yl)benzamide compounds and salts...
US-9,814,724 Antitumor effect potentiator and antitumor agent
The present invention provides an antitumor effect potentiator for enhancing antitumor activity of an antitumor agent comprising tegafur in a therapeutically...
US-9,814,723 Compositions and methods for prophylaxis and therapy for Meniere's disease
Provided are articles of manufacture, compositions and methods for prophylaxis and/or therapy for disorders involving dizziness and/or vertigo. The articles of...
US-9,814,722 Heteroaryl substituted pyrrolo[2,3-B] pyridines and pyrrolo[2,3-B] pyrimidines as janus kinase inhibitors
The present invention provides heteroaryl substituted pyrrolo[2,3-b]pyridines and heteroaryl substituted pyrrolo[2,3-b]pyrimidines that modulate the activity of...
US-9,814,721 Use of inhibitors of bruton'S tyrosine kinase (BTK)
Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance...
US-9,814,720 Compositions and methods of inhibiting IL-17 expression of neutrophils
A method of inhibiting IL-17 expression in neutrophils of a subject in need thereof includes administering to neutrophils of the subject a therapeutically...
US-9,814,719 Methods and compositions for treating bacterial infection
The present disclosure relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present disclosure...
US-9,814,718 MNK inhibitors and methods related thereto
The present invention relates to compounds according to Formula (I): ##STR00001## or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof,...
US-9,814,716 Treatment of autoimmune disease
Provided herein are compositions and methods for the treatment of autoimmune diseases, including lupus, uveitis and encephalitis. Said compositions useful for...
US-9,814,715 Liver X receptor modulators
Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions...
US-9,814,714 Kinase modulation, and indications therefor
The present disclosure provides methods of treating a subject suffering from or at risk of a BRAF V600 mutation or BRAF fusion mutation related disease or...
US-9,814,713 Solid forms of 2-(tert-butylamino)-4-((1R,3R,4R)-3-hydroxy-4-methylcyclohexylamino)-pyri- ...
Provided herein are formulations, processes, solid forms and methods of use relating to 2 ...
US-9,814,712 (S)-pirlindole and its pharmaceutically acceptable salts for use in medicine
(S)-pirlindole or its pharmaceutically acceptable salts, as well as pharmaceutical compositions comprising the same for use in the therapeutic treatment and...
US-9,814,711 Antitubercular composition comprising rifampicin, isoniazid, ethambutol and pyrazinamide and its process of...
The present invention relates to a monolayer tablet for use in the treatment of tuberculosis comprising a mixture of: --granules comprising isoniazid,...
US-9,814,710 Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome
The present invention relates to prolonged release pharmaceutical dosage forms comprising hydromorphone or a pharmaceutically acceptable salt thereof and...
US-9,814,709 Bruton's tyrosine kinase inhibitor
The present invention provides a Bruton's tyrosine kinase inhibitor, which is a compound represented by formula (I) or a pharmaceutically acceptable salt,...
US-9,814,708 Formulations and pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2...
US-9,814,707 Cancer stem cell proliferation inhibitor and intracellular active oxygen accumulation inducer
The present invention is directed to provide cancer stem cell proliferation inhibitors and inducers of intracellular accumulation of reactive oxygen species. To...
US-9,814,706 Hydrobromide salt of pridopidine
This invention relates to a new salt of Pridopidine, a drug substance currently in development for the treatment of Huntington's disease. More specifically the...
US-9,814,705 Intranasal spray device containing pharmaceutical composition
An intranasal spray device contains a composition for the intranasal delivery of fentanyl or a pharmaceutically acceptable salt thereof to an animal includes an...
US-9,814,704 Substituted pyrrolo[2,3-b]pyridines as MLK inhibitors
Provided are compounds having an inhibitory effect on Mixed Lineage Kinases. The compounds include substituted pyrrolo[2,3-b]pyridines having Formula IX ...
US-9,814,703 Methods for treating cancer by activation of BMP signaling
Methods for treating cancer by activation of the Bmp pathway are disclosed. In particular, the invention relates to methods of treating cancer using agents that...
US-9,814,702 Ocular formulations for drug-delivery and protection of the anterior segment of the eye
The present application relates to topical formulations comprising Compound-I ##STR00001## or its free base, and a second active agent selected from nicotinic...
US-9,814,701 Compositions and methods for the treatment of macular degeneration
The present invention is directed to topical ophthalmic compositions of a lipophilic compound and an oligomeric or polymeric carrier wherein the compositions...
US-9,814,700 Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents
The present invention is directed to inhibitors of S-nitrosoglutathione reductase (GSNOR), pharmaceutical compositions comprising such GSNOR inhibitors, and...
US-9,814,699 Chemical compounds
Disclosed are compounds of Formula III. Also disclosed are salts of the compounds, pharmaceutical composition comprising the compounds or salts, and methods for...
US-9,814,698 Selective androgen receptor degrader (SARD) ligands and methods of use thereof
This invention provides novel indole, indazole, benzimidazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD)...
US-9,814,697 Composition for nonalcoholic fatty liver disease (NAFLD)
The present invention provides a compound of Formula (I) or pharmaceutical acceptable thereof, wherein `R` is herein described. In addition, the invention...
US-9,814,696 Use of coumarin derivatives for the preparation of drugs for treating skin diseases
A compound of formula (I-1) ##STR00001## wherein n equals 0 or 1, Z represents O or S, R1 represents one group chosen among the group consisting of hydrogen,...
US-9,814,695 Ophthalmic solutions for glaucoma and conjunctivitis treatment
This invention generally relates to an ophthalmic solution comprising cannabinoids for the treatment of glaucoma. Also disclosed is an ophthalmic solution...
US-9,814,694 Lipidic furan, pyrrole, and thiophene compounds for treatment of cancer, neurological disorders, and fibrotic...
Compounds, methods, and compositions are provided for the treatment of cancer, neurological disorders, and fibrotic disorders. Specifically, the invention...
US-9,814,693 Veterinary use of dianhydrogalactitol, diacetyldianhydrogalactitol, and dibromodulcitol to treat malignancies
The present invention is directed to methods for treatment of malignancies in companion animals employing dianhydrogalactitol, diacetyldianhydrogalactitol, and...
US-9,814,692 Fumarate ester dosage forms
Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In...
US-9,814,691 Fumarate ester pharmaceutical compositions
Described herein are pharmaceutical compositions comprising fumarate esters, methods for making the same, and methods for treating subjects in need thereof. In...
US-9,814,690 Gel composition for treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or...
Dermatological/cosmetic compositions suited for preventing or treating cell differentiation and/or proliferation and/or keratinization disorders, including...
US-9,814,689 Enterically coated cysteamine, cystamine and derivatives thereof
The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations...
US-9,814,688 Antimicrobial compositions and methods for their use
Topical and wash compositions comprising a polymeric biguanide or a bis(biguanide) compound, a chelating agent and a buffering agent and methods for using these...
US-9,814,687 Transdermal pharmaceutical compositions including C-SERMs for low testosterone levels in men
Formulations for transdermal pharmaceutical compositions including clomiphene-like selective estrogen receptor modulators (C-SERMs) in combination with...
US-9,814,686 Rolled collagen carrier
The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen...
US-9,814,685 Taxane particles and their use
Compositions are provided that include having at least 95% by weight of a taxane, or a pharmaceutically acceptable salt thereof, where the particles have a mean...
US-9,814,684 Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s)
The invention relates to liquid pharmaceutical formulations for oral administration with the modified release of active principle(s), excluding amoxicillin,...
US-9,814,683 Shell-forming compositions for soft capsules and soft capsules
A shell-forming composition for a soft capsule comprising a non-gelatin component as the chief component, wherein the shell-forming composition is able to...
US-9,814,682 Vaccination with immuno-isolated cells producing an immunomodulator
The present invention relates to immuno-protected encapsulated cells producing an immunomodulator, for example GM-CSF (granulocyte-macrophage colony stimulating...
US-9,814,681 Delayed release drug formulation
In a delayed release formulation comprising a core containing a drug and a delayed release coating for providing intestinal release, release of the drug in the...
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