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Patent # Description
US-9,827,265 Method for attenuating free radical formation resulting from a bodily insult
A method is provided for attenuating free radical formation resulting from a bodily insult. The method includes administering bicarbonate to the body of a...
US-9,827,264 Method and system for the treatment of medical conditions by intravenous therapy
A method and system for identifying and treating various medical conditions caused by toxins, pathogens, hormonal imbalances and other factors involving...
US-9,827,263 2'-methoxy substituted oligomeric compounds and compositions for use in gene modulations
Compositions comprising first and second oligomers are provided wherein at least a portion of the first oligomer is capable of hybridizing with at least a...
US-9,827,262 Rutin-rich extract and method of making same
A method of obtaining a rutin-rich extract from a plant and a rutin-rich extract of Uncaria elliptica thus obtained.
US-9,827,261 Etoposide and prodrugs thereof for use in targeting cancer stem cells
The present invention pertains to the use of podophyllotox in derivatives, such as CAP7.1, in methods for inhibition of and/or prevention of the growth and/or...
US-9,827,260 Composition for buffered aminoalkyl glucosaminide phosphate compounds and its use for enhancing an immune response
There is provided a composition comprising an aminoalkyl glucosaminide phosphate compound or a pharmaceutically salt thereof and a buffer for use as an...
US-9,827,259 Methods of modulating the sialylation of Angptl4
The present disclosure provides a biochemical basis of nephrotic syndrome and provides and explanation for the observed proteinuria and other effects. As a...
US-9,827,258 Bicyclic aryl sphingosine 1-phosphate analogs
Compounds that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphin-gosine analogs that, after phosphorylation, can...
US-9,827,257 Antitumoral compounds
A compound of general formula (I) wherein A, Y, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and R.sub.6 take various meaning or use in the treatment of cancer.
US-9,827,256 Compositions for administration of zoledronic acid or related compounds for treating lower back pain
Oral dosage forms of osteoclast inhibitors, such as nitrogen-containing bisphosphonates, such as zoledronic acid, can be used to treat or alleviate pain or...
US-9,827,255 Fumagillol derivatives
Disclosed are compounds of Formula 1, ##STR00001## stereoisomers thereof and pharmaceutically acceptable salts of the compounds and stereoisomers, wherein...
US-9,827,254 Method of treating acute coronary syndromes
The present invention relates to methods and compositions designed for the treatment or management of acute coronary syndromes, particularly, unstable angina...
US-9,827,253 Prodrug salts
Provided are novel prodrug salts of selective aquaporin inhibitors, their use as pharmaceuticals, and pharmaceutical compositions comprising them, and novel...
US-9,827,252 Calmodulin inhibitors for the treatment of ribosomal disorders and ribosomapathies
The present invention relates generally to methods, compositions and kits for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia...
US-9,827,251 Dosing regimen for sedation with CNS 7056 (remimazolam)
The invention relates to a dosing regimen for sedation with the fast-acting benzodiazepine CNS 7056 in combination with an opioid, in particular fentanyl,...
US-9,827,250 Lens incorporating myopia control optics and muscarinic agents
Ophthalmic devices, such as contact lenses, may incorporate myopia control optics in combination with therapeutic agents also known to control myopia to create...
US-9,827,249 Use of condensed benzo[B]thiazine derivatives as cytoprotectants
The present invention relates to arylthiazine compounds, metabolites, N-oxides, amides, esters, pharmaceutically acceptable salts, hydrates and solvates thereof...
US-9,827,248 Therapeutic compounds and uses thereof
Described herein are compounds of Formula (I) or Formula (VI), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided...
US-9,827,247 Heterocyclyl compounds
The present invention is related to heteroaryl compounds as MEK inhibitors. The invention includes heteroaryl compounds of formula I, their tautomers and...
US-9,827,246 Biomarkers of response to NAE inhibitors
Disclosed herein are markers whose mutational status is associated with sensitivity to treatment with NAE inhibitors. Mutational status is determined by...
US-9,827,245 Keratin compositions comprising halofuginone
Described herein are compositions of keratin-based biomaterials together with halofuginone and methods of using thereof.
US-9,827,244 Cap/endo dual inhibitors and their use in the treatment, amelioration or prevention of a viral disease
The present invention relates to a compound having the general formula (V), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph,...
US-9,827,243 Pharmaceutical formulations, processes, solid forms and methods of use relating to ...
Provided herein are formulations, processes, solid forms and methods of use relating to ...
US-9,827,242 Method of treatment for mental disorders
The invention relates to a medicament or a method for treating mental disorders, in detail, ADHD comprising lurasidone, or a combination of lurasidone and a...
US-9,827,241 Injectable flowable composition comprising buprenorphine
The present invention is directed to a buprenorphine sustained release delivery system capable of delivering buprenorphine, a metabolite, or a prodrug thereof...
US-9,827,240 Polymorphic forms of naltrexone
This invention relates to the discovery of novel polymorphic forms of naltrexone, including solvates, hydrates, anhydrous and other crystalline forms and...
US-9,827,239 Oligomer-opioid agonist conjugates
The invention provides compounds that are chemically modified by covalent attachment of a water--soluble oligomer. A compound of the invention, when...
US-9,827,238 Drug treatment of overactive bladder
Provided are methods of treating an overactive bladder in a patient which include: administering a Myosin II ATPase inhibitor compound; or administering an X...
US-9,827,237 Compounds useful for treating diseases caused by retroviruses
Methods for preventing or treating retroviral infection not HIV and/or for preventing, inhibiting or treating a disease caused by the retroviral infection...
US-9,827,236 Method of inhibiting the glycation of nutrient and endogenous proteins and peroxidation of nutrient and...
Methods for reducing the glycation of nutrient and endogenous proteins and methods for reducing the peroxidation of nutrient and endogenous lipids are provided...
US-9,827,235 Pharmaceutical compositions comprising antibacterial agents
Pharmaceutical compositions comprising cefepime or a pharmaceutically acceptable derivative, and a compound of Formula (I) or a stereoisomer or a...
US-9,827,234 Dose-dumping resistant controlled release dosage form
The present invention provides a simple and improved dose form that is capable of providing a controlled release of methylphenidate contained in the core...
US-9,827,233 Methods of treating behavioral syndromes using pipradrol
Methods of treating behavioral syndromes by administering a pharmaceutical composition of pipradrol or a pharmaceutically acceptable salt thereof are provided....
US-9,827,232 Protein tyrosine phosphatase inhibitor, preparation method and uses thereof
Disclosed in the present invention is a protein tyrosine phosphatase inhibitor. The preparation method therefor is: extracting the crude product from the Isaria...
US-9,827,231 Liquid pharmaceutical composition
The present invention provides a physically and chemically stable pharmaceutical liquid composition including sodium picosulfate, magnesium oxide, citric acid...
US-9,827,230 Pharmaceutical compositions
The present invention relates to the field of methods for providing pharmaceutical compositions comprising poorly water-soluble drugs. In particular the present...
US-9,827,229 Small molecule securinine and norsecurinine analogs and their use in cancers, inflammatory diseases and infections
The present invention relates to novel securinine and norsecurine analogs and their applicapility in treating cellular proliferative disorders.
US-9,827,228 Opioid receptor modulators and use thereof
Disclosed is an in vitro screening method for identifying an antagonist-to-agonist allosteric modifier of a mu-opioid receptor and an in vivo method for...
US-9,827,227 Controlled release pharmaceutical formulations of nitazoxanide
Solid dosage formulations of nitazoxanide or a nitazoxanide analogue are provided that comprise a controlled release portion and an immediate release portion....
US-9,827,226 Substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-ones
Disclosed are substituted 5-(3,5-dimethylisoxazol-4-yl)indoline-2-one compounds, pharmaceutical compositions comprising at least one such 4 substituted...
US-9,827,225 Use of prostacyclin antagonists for treating ocular surface nociception
The present invention relates generally to the use of compositions and methods for treating nociceptive events that occur on the ocular surface in association...
US-9,827,224 Methods and compositions for ameliorating pancreatic cancer
Embodiments of the present invention include methods and compositions for ameliorating cancer. Some embodiments include methods and compositions for...
US-9,827,223 Selective ablation of pain-sensing neurons by administration of a vanilloid receptor agonist
The present invention provides methods and kits for the selective ablation of pain-sensing neurons. The methods comprise administration of a vanilloid receptor...
US-9,827,222 Treating or preventing nephrogenic diabetes insipidus
In certain embodiments, the disclosure relates to methods of treating or preventing nephrogenic diabetes insipidus comprising administering an effective amount...
US-9,827,221 Crystalline solids of a metAP-2 inhibitor and methods of making and using same
The disclosure is in part directed to crystalline forms of 6-O-(4-dimethylaminoethoxy)cinnamoyl fumagillol and variants thereof.
US-9,827,220 Treatment for ischemic stroke
Granulocyte colony-stimulating factor (G-CSF; a stem cell enhancer and facilitator), DETC-MeSO (a glutamate receptor partial antagonist and anti-excitotoxicity...
US-9,827,219 Compositions and methods for lowering levels of high-sensitivity C-reactive protein (HS-CRP) in a subject
The present disclosure provides methods for treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy...
US-9,827,218 Omega-3 fatty acid articles of manufacture, and methods and apparatus for making same
Embodiments of the present invention are directed to methods, apparatus and articles of manufacture that feature omega-3 fatty acids co-processed with flavonoid...
US-9,827,217 Pharmaceutically acceptable salts of B-guanidinopropionic acid with improved properties and uses thereof
The present invention relates to new pharmaceutical salts of .beta.-GPA which exhibit improved physical properties. In particular, the invention relates to...
US-9,827,216 Nutritional support to prevent and/or mitigate bone marrow toxicity from a cancerous tumor
The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or...
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