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Patent # Description
US-9,840,721 Recombinant retrovirus pseudotyped with E2 alphavirus glycoprotein
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus...
US-9,840,720 Materials and methods relating to packaging cell lines
Lentiviral packaging cells and methods for producing the same are provided herein. Specifically, lentiviral packaging cells capable of producing lentiviral...
US-9,840,719 Variant AAV and compositions, methods and uses for gene transfer to cells, organs and tissues
The invention relates to adeno-associated virus (AAV) serotype AAV-Rh74 and related AAV vectors, and AAV-Rh74 and related AAV vector mediated gene transfer...
US-9,840,718 Minimal piggyBac vectors for genome integration
Disclosed are genetic delivery systems that utilize genetic elements of the piggyBac family transposon system, and methods of introducing nucleic acid into...
US-9,840,717 Plant with reduced protein productivity in seeds and method for producing same
According to the present invention, a gene having a novel function that can cause an increase or decrease in seed protein content is searched for. A chimeric...
US-9,840,716 Resveratrol-enriched rice and the use thereof
The present invention relates to resveratrol-enriched transgenic rice for biosynthesizing resveratrol at high concentration, in which resveratrol synthase genes...
US-9,840,715 Methods and compositions for delaying senescence and improving disease tolerance and yield in plants
The present invention provides novel compositions for use to enhance crop performance. Specifically, the present invention provides for delayed senescence...
US-9,840,714 Method for promoting efficiency of gene introduction into plant cells
A method for gene introduction by which higher efficiency for gene introduction than that by the conventional Agrobacterium method may be attained simply and...
US-9,840,713 CRISPR-Cas component systems, methods and compositions for sequence manipulation
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and...
US-9,840,712 CD133 aptamers for detection of cancer stem cells
The present disclosure relates to RNA aptamers and uses thereof, in particular, aptamers which specifically bind to CD133 and which demonstrate superior tumor...
US-9,840,711 Methods of treating cancer
A method of treating cancer is disclosed. The method comprises administering to the subject a therapeutically effective amount of a pharmaceutical composition...
US-9,840,710 Antisense compounds targeting leucine-rich repeat kinase 2 (LRRK2) for the treatment of parkinsons disease
The present disclosure relates generally to compounds comprising oligonucleotides complementary to a Leucine-Rich-Repeat-Kinase (LRRK2) RNA transcript. Certain...
US-9,840,709 Antisense compounds targeting genes associated with cystic fibrosis
The present disclosure relates generally to compounds comprising oligonucleotides complementary to a cystic fibrosis transmembrane conductance regulator (CFTR)...
US-9,840,708 Compositions and methods for the modulation of DNA damage responses using BAL1 and BBAP
The invention provides methods and compositions for enhancing the efficacy of cancer therapies through modulation of BAL1 and/or BBAP. Also provided are methods...
US-9,840,707 Modified TGF-beta2 oligonucleotides
The invention refers to an oligonucleotide consisting of 10 to 18 nucleotides of selected regions of the TGF-beta2 nucleic acid sequence, which comprises...
US-9,840,706 Antisense nucleic acids
Provided is a drug that allows highly-efficient skipping of exon. The present invention provides an antisense oligomer wherein two or more unit oligomers...
US-9,840,705 Materials and methods for treatment of pulmonary arterial hypertension
The invention relates to the use of microRNA 96 and precursors and mimics thereof for the inhibition of vascular cell proliferation and/or vascular remodelling,...
US-9,840,704 Molecular targets for the prevention and/or treatment of fibrosis, hypertrophic scars or keloids
The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting...
US-9,840,703 Methods and compositions for the production of siRNAs
The technology described herein relates to siRNAs, e.g., methods and compositions relating to the production of siRNAs in bacterial cells.
US-9,840,702 CRISPR-based compositions and methods of use
This invention pertains to modified compositions for use in CRISPR systems, and their methods of use. In particular, length-modified and chemically-modified...
US-9,840,701 Porous membrane having immobilized enzyme, porous membrane composite including the same, and preparation method...
Disclosed herein is a porous membrane having an immobilized enzyme wherein the enzyme is immobilized within pores which are three-dimensionally connected to...
US-9,840,700 DNA cleavage enzyme
There is provided an enzyme which has an activity of cleaving a phosphodiester bond of deoxyribonucleotide having a damaged base and deoxyribonucleotide...
US-9,840,699 Methods for nucleic acid editing
Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including...
US-9,840,698 DNA polymerases with increased 3'-mismatch discrimination
Disclosed are mutant DNA polymerases having increased 3'-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are...
US-9,840,697 Fusion polymerases
Fusion polypeptides having a heterologous 5'-3' exonuclease domain linked to a polymerase that does not naturally have 5'-3' exonuclease activity, as well as...
US-9,840,696 Nucleic acids encoding SB10 variants
The present invention refers to hyperactive variants of a transposase of the transposon system Sleeping Beauty (SB). The invention further refers to...
US-9,840,695 Plant technology
Genetic constructs capable of manipulating fructan biosynthesis in photosynthetic cells of a plant, said genetic constructs include a promoter operatively...
US-9,840,694 Removal of contaminating viruses from AAV preparations
The present invention relates to a separation of viruses of an essentially spherical shape from viruses with a rod-like shape that are comprised in a sample,...
US-9,840,693 Polypeptide hydrogels and uses related thereto
This disclosure relates to self-assembling peptides that form hydrogels comprising peptide sequences for the activation of signaling pathways. In certain...
US-9,840,692 Closed system device and methods for gas permeable cell culture process
Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media,...
US-9,840,691 One-way separator for retaining and recirculating cells
The invention relates to the use of single- or multilayer plastic web plates in a sloped channel-type solid material separator with a lamella package.
US-9,840,690 Systems and methods for autologous biological therapeutics
An autologous cell concentrating system and method are disclosed. The system has a blood separation component, a first vessel, a second vessel, a first valve, a...
US-9,840,689 Container for biopharmaceutical content
A container (10) for receiving biopharmaceutical content (C) in liquid, fluid or gaseous form, includes a peripheral wall (12) that is closed on itself, at...
US-9,840,688 Bioreactor chamber
A bioreactor system includes a sample chamber capable of receiving a specimen and a cover which can be placed on the chamber to enclose the specimen within the...
US-9,840,687 Artificial aging apparatus for spirits and other alcoholic beverages
An artificial aging apparatus for spirits and other alcoholic beverages to decrease the time it takes for alcoholic beverages to mature. The artificial aging...
US-9,840,686 Wrinkle reducing and deodorizing dryer sheet and methods of making and using
Provided are wrinkle reducing and deodorizing dryer sheets and methods of making and using the dryer sheets. In one form of the dryer sheet, the wrinkle...
US-9,840,685 Ternary compositions of methyl perfluoroheptene ethers and trans-1,2-dichloroethylene, and uses thereof
Disclosed are compositions comprising 90 to 99 weight percent trans-1,2-dichloroethylene, from 0.1 to 8 weight percent methylperfluoroheptene ethers and from...
US-9,840,684 Compositions containing alkyl sulfates and/or alkoxylated alkyl sulfates and a solvent comprising a diol
The present invention relates generally to compositions containing an anionic surfactant selected from the group consisting of alkyl sulfates, alkoxylated alkyl...
US-9,840,683 Alkaline detergent composition containing a carboxylic acid/polyalkylene oxide copolymer for hard water scale...
An alkaline detergent is described which includes the use of a copolymer in combination with an alkali metal hydroxide. The detergent maintains cleaning...
US-9,840,682 Cleaning compositions with improved sudsing profile comprising a cationic polymer and silicone mixture
The present invention relates to detergent or cleaning compositions with improved sudsing profile, which comprise a cationic polymer, an organomodified silicone...
US-9,840,680 Fragrance compositions comprising ionic liquids
The present invention relates to a fragrance composition comprising ionic liquids for enhanced evaporation of the perfume raw materials. The invention also...
US-9,840,679 Gelling nanofluids for dispersion stability
A gelling nanofluid and methods for manufacture are provided. The composition and methods for manufacture produce nanofluid gels so that the settlement of...
US-9,840,678 Methods of inhibiting precipitation of biodiesel fuel components
Embodiments of the invention provide a method of inhibiting precipitation of biodiesel fuel components. The method includes providing a biodiesel fuel...
US-9,840,677 Biofuel product and method for the production thereof
The invention relates to a method for producing a biofuel from an aqueous mixture of carbonized biomass obtained by means of a method for the hydrothermal...
US-9,840,676 Diesel and turbine fuels from ethanol
A three step method for the conversion of ethanol into fuels that can be utilized as full-performance military jet or diesel fuels. Embodiments of the invention...
US-9,840,675 System and method for recovering gas containing CO.sub.2 and H.sub.2S
The system is provided with: a first heat exchanger which is interposed at an intersection between a rich solution supply line and a lean solution supply line,...
US-9,840,674 Process for converting petroleum feedstocks comprising an ebullating-bed hydrocracking stage, a maturation...
The invention relates to a process for converting a hydrocarbon-containing feedstock containing at least one hydrocarbon fraction having a sulphur content of at...
US-9,840,673 Systems and methods for removing sulfur and halogens
Provided herein are systems and methods for removing halogens and sulfur from used oil. The used oil is heated and aerated, followed by rapid vaporization and...
US-9,840,672 ZSM-22 zeolite, hydroisomerization catalyst and method for producing same, and method for producing hydrocarbon
A method for producing a hydroisomerization catalyst includes a first step of preparing a support precursor by heating a mixture containing an ion-exchanged...
US-9,840,671 Delayed coking process
The present invention provides a delayed coking process comprising a step of subjecting a mixed feed comprises residual heavy hydrocarbon feedstock and bio oil...
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