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Patent # Description
US-9,855,282 Method for scheduling ovulation
The invention relates to a method for scheduling ovulation in a female subject, which method comprises administering ulipristal acetate (UPA) to the female...
US-9,855,281 Libido-enhancing therapeutic and use
A composition for enhancing libido of a pharmaceutically effective amount of a libido-enhancing therapeutic of ...
US-9,855,280 Nanoparticles containing azolium and N-heterocyclic carbene compounds and use thereof
The present application provides a composition comprising a core formed by gold nanoparticle, a compound of Formula (I): ##STR00001## wherein dashed lines in...
US-9,855,279 Methods of treating oral mucositis
Methods and kits for treating oral mucositis are disclosed. The treatment comprises administering to a patient in need thereof a Reactive Oxygen Species...
US-9,855,278 Modified release preparations containing oxcarbazepine and derivatives thereof
Controlled-release preparations of oxcarbazepine and derivatives thereof for once-a-day administration are disclosed. The inventive compositions comprise...
US-9,855,277 Use of 5H-dibenz/b,f/azepine-5-carboxamide derivatives for treating fibromyalgia
The use of 5H-dibenz/b,f/azepine-5-carboxamide derivatives for treating fibromyalgia. Useful 5H-dibenz/b,f/azepine-5-carboxamide derivatives include compounds...
US-9,855,276 Combination therapies for the treatment of Alzheimer's disease and related disorders
The present invention relates to combination therapies for treating Alzheimer's disease or an amyloidosis-associated pathological condition comprising...
US-9,855,275 Aryl-or heteroaryl-substituted benzene compounds
The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing...
US-9,855,274 Phenoxy acetic acids and phenyl propionic acids as PPAR delta agonists
Phenoxy acetic acids and phenyl propionic acids and their use in treating type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, or...
US-9,855,273 Combination therapy for MDS
Disclosed are compositions and methods for the treatment of disorders such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). The disclosed...
US-9,855,272 1H-pyrazolo[3,4-B]pyridines and therapeutic uses thereof
Provided herein are compounds according to Formula I and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various...
US-9,855,271 Quinazolinones as bromodomain inhibitors
The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy. ...
US-9,855,270 Methods and compositions for modulating estrogen receptor mutants
Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an...
US-9,855,269 Aminoquinazoline and pyridopyrimidine derivatives
The invention provides a method of inhibiting angiogenesis in a patient by administering a compound of formula (I): ##STR00001## wherein R.sup.1 R.sup.2 and...
US-9,855,268 Triazolo[4,5-d]pyrimidine derivatives
Compounds of the formula I ##STR00001## in which R.sup.1 and R.sup.2 have the meanings indicated in claim 1, are inhibitors of GCN2, and can be employed,...
US-9,855,267 Histone deacetylase inhibitors and compositions and methods of use thereof
Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use. ##STR00001##
US-9,855,266 Treatment for osteoarthritis by intra-articular administration of a cis-imidazoline
Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic...
US-9,855,265 Methods for treating cancer with TrkA receptor tyrosine kinase antagonists
The present disclosure relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same, said compounds being...
US-9,855,264 Pharmaceutical compositions
Methods and compositions are provided which comprise effective amounts of an analgesic to treat a subject, including reducing or eliminating an adverse effect...
US-9,855,263 Tamper-resistant dosage form with immediate release and resistance against solvent extraction
A tamper-resistant pharmaceutical dosage form comprising a multitude of particles which comprise a pharmacologically active compound, a polyalkylene oxide, and...
US-9,855,262 Systems and methods for treating an opioid-induced adverse pharmacodynamic response
Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient...
US-9,855,261 Polymeric compound having camptothecin compound and anti-cancer effect enhancer bound thereto, and use of same
The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP...
US-9,855,260 Quinolinone derivatives
The present invention relates to compounds of the formula (I), ##STR00001## salts thereof, to pharmaceutical compositions containing them and their use in...
US-9,855,259 Processes of making and crystalline forms of a MDM2 inhibitor
The present invention provides processes for making 2-((3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsu- ...
US-9,855,258 Dose-dumping resistant controlled release dosage form
The present invention provides a simple and improved dosage form that is capable of providing a controlled release of methylphenidate contained in the core...
US-9,855,257 4-alkynyl imidazole derivative and medicine comprising same as active ingredient
There are provided 4-alkynylimidazole derivatives represented by the following general formula (I) or pharmaceutically acceptable salts thereof; the derivatives...
US-9,855,256 Cyclooxygenase inhibitor and calcium channel antagonist compositions and methods for use in urological procedures
Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the urinary tract during...
US-9,855,254 Methods of treating hepatic encephalopathy
The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic...
US-9,855,253 Pharmaceutical composition containing FK506 derivative for treating fungal infection caused by genus...
The present invention relates to a pharmaceutical composition containing FK506 derivative for treating a fungal infection caused by the genus Cryptococcus or...
US-9,855,252 Methods of treating keratin hyperproliferation disorders using mTOR inhibitors
A method of treating or preventing keratin hyperproliferation skin disorders is set forth. The method includes the administration of an mTOR inhibitor to a...
US-9,855,251 Use of metformin in combination with a glucokinase activator and compositions comprising metformin and a...
The present invention provides uses of a glucokinase activator in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose,...
US-9,855,250 Method to treat lung cancer
One example embodiment relates to a method of treating lung cancer by administering a compound of formula I to a subject in need thereof. Another embodiment...
US-9,855,249 Isoxazole compounds and methods for the treatment of cystic fibrosis
The invention relates to a compound of Formula I and methods of treating cystic fibrosis comprising the step of administering a therapeutically effective amount...
US-9,855,248 Polymorph of itraconazole with improved pharmaceutical properties
The present invention provides a new crystalline form of itraconazole as well as the method of making same.
US-9,855,247 Dental anesthetic comprising tetracaine and a vasoconstrictor for intranasal administration
The present invention relates to tetracaine based anesthetic formulations and methods of use thereof. The invention further relates to topical formulations of...
US-9,855,246 Stable preservative-free mydriatic and anti-inflammatory solutions for injection
The present invention relates to stable, preservative- and antioxidant-free liquid formulations of phenylephrine and ketorolac for injection.
US-9,855,245 Methods for improving lipid profiles using atrasentan
The present disclosure is directed to methods for reducing cardiovascular risk in a human subject by administering atrasentan, or a pharmaceutically acceptable...
US-9,855,244 O/W-emulsion-type topical pharmaceutical compositions containing a retinoid
O/W-emulsion-type topical pharmaceutical compositions including a retinoid are described. Also described, is a topical pharmaceutical composition including by...
US-9,855,243 Topical anti-inflammatory pharmaceutical composition with zileuton cream formulation
Provided herein is a zileuton cream type topical anti-inflammatory pharmaceutical composition, and more particularly, a zileuton cream type topical...
US-9,855,242 Composition for an immunomodulation
The present invention relates to a composition for the immunomodulation and uses and methods associated therewith.
US-9,855,241 Treatment of circadian rhythm disorders
Embodiments of the invention relate to the use of a melatonin agonist in the treatment of free running circadian rhythms in patients, including light perception...
US-9,855,240 Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or...
US-9,855,239 Methods for the treatment and prevention of age-related retinal dysfunction
A method of treating or preventing age-related retinal dysfunction involves administering to a patient a pharmaceutically effective amount of a synthetic...
US-9,855,238 Compositions comprising 15-HEPE and methods of using the same
The present invention relates to the compositions comprising 15-HEPE and methods of treatment relating to same.
US-9,855,237 Methods of treating mixed dyslipidemia
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
US-9,855,236 Pharmaceutical compositions comprising DGLA and/or 15-HETrE and methods of use thereof
The present disclosure provides compositions comprising fatty acids, or derivatives thereof (e.g., C1-C4 esters) including, for example, DGLA, and/or 15-HETrE,...
US-9,855,235 Compositions and methods for modulating metabolic pathways
Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or...
US-9,855,234 Diclofenac sublingual spray
The present invention is directed to diclofenac sublingual spray formulations. The present invention is also directed to methods for treating pain and...
US-9,855,233 Methods of quantifying N.sup.2-(1-carboxyethyl)-2'-deoxy-guanosine (CEdG) and synthesis of oligonucleotides...
Methods of quantifying a N.sup.2-carboxyethyl-2'-deoxyguanosine (CEdG) levels in biological samples and comparing those levels to known normal levels can...
US-9,855,232 Crystalline forms of bimatoprost acid, methods for preparation, and methods for use thereof
The invention provides new crystalline forms of 7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-e- noic acid. This compound is commonly...
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