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Patent # Description
US-9,867,844 Peptide nucleic acid of subgroup J avian leukosis virus and uses thereof
A peptide nucleic acid of subgroup J avian leukosis virus and uses of the same are provided. The sequence of the peptide nucleic acid is one or more selected...
US-9,867,843 Defibrotide for use in prophylaxis and/or treatment of graft versus host disease (GVHD)
Defibrotide for use in prophylaxis and/or treatment of Graft versus Host Disease (GVHD) in humans is disclosed, preferably in hematopoietic stem cell...
US-9,867,842 Methods and compositions for reversing disruption of the glycocalyx, inflammation, and oxidative damage
A composition for treating multiple disease causes including a glycocalyx restoring and maintaining compound in an oral dosage form. A method of treating...
US-9,867,841 Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells
Methods are provided herein for use of E-selectin antagonists for mobilizing cells, such as hematopoietic cells, hematopoietic stem cells and progenitor cells,...
US-9,867,840 Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain...
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
US-9,867,839 Osteoclast inhibitors for joint conditions
Oral dosage forms of osteoclast inhibitors, such as neridronic acid and zoledronic acid, in an acid or a salt form, can be used to treat or alleviate pain or...
US-9,867,838 Methods for treating heart failure using bisphosphonate compositions
The present invention provides for methods for treating and/or reducing cardiac dysfunction by administering to subject a therapeutically effective amount of a...
US-9,867,837 Compositions for treating neurological disorders
The present invention relates to compositions and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid .beta....
US-9,867,836 Lavage and/or infusion using CSA compounds for increasing fertility in a mammal
Increasing fertility in a mammal utilizes cationic steroidal antimicrobial (CSA) compounds and CSA-containing compositions. Such treatment in a mammal includes...
US-9,867,835 Methods and compositions for treating and preventing viral infections
A method of treating or preventing a systemic viral infection in a mammal by administering a pharmaceutically acceptable composition selected from the group...
US-9,867,834 Non-systemic topical compositions comprising corticosteroids
Described herein are topical, non-systemic, slow releasing oral pharmaceutical compositions, methods for making the same, and methods for treating subjects in...
US-9,867,833 Serine/threonine kinase inhibitors
Compounds having the formula I wherein R.sup.1, X.sup.1, X.sup.2, X.sup.3 and X.sup.4 as defined herein are inhibitors of ERK kinase. Also disclosed are...
US-9,867,832 Pharmaceutical composition for inhibiting immune response through inducing differentiation into regulator T...
The present invention relates to new medical use of (tetrahydropyran-4-yl)-[2-phenyl-5-(1,1-dioxo-thiomorpholine-4-yl)methyl-- 1H-indol-7-yl]amine, and more...
US-9,867,831 Combination treatment of acute myeloid leukemia and myelodysplastic syndrome
The present invention relates to the use of Volasertib or a salt thereof or the hydrate thereof in combination with Quizartinib or a salt thereof or the hydrate...
US-9,867,830 Use of (2R, 6R)-hydroxynorketamine, (S)-dehydronorketamine and other stereoisomeric dehydro and hydroxylated...
The disclosure provides pharmaceutical preparations containing (2R,6R)-hydroxynorketamine, or (R)- or (S)-dehydronorketamine, or other stereoisomeric dehydro or...
US-9,867,829 Stable pharmaceutical composition containing ...
The present invention relates to a stable pharmaceutical composition comprising amorphous or crystalline linagliptin or a pharmaceutically acceptable salt of...
US-9,867,828 Aminopterin dosage forms
Embodiments of the present invention provide dosage forms and methods for treating a patient with an inflammatory disorder with a therapeutically effective...
US-9,867,827 Methods and formulations for topical treatment of psoriasis
A pharmaceutical formulation and topical administration thereof for the treatment of psoriasis or any one or more symptoms associated therewith. The formulation...
US-9,867,826 Heterocycles as modulators of kinase activity
The invention provides novel heterocyclic amines according to Formula (I) their manufacture and use for the treatment of hyperproliferative diseases, such as...
US-9,867,825 Pharmaceutical combination comprising binimetinib
A combination of a CDK4/6 inhibitor and a MEK inhibitor for the treatment of diseases such as cancer.
US-9,867,824 Heterocyclic compounds and uses thereof
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
US-9,867,823 Neuroprotective bicyclic compounds and methods for their use in treating autism spectrum disorders and...
Embodiments of this invention provide compositions and methods for therapeutic use of diketopiperazines including cyclic G-2-Allyl Proline and other cyclic...
US-9,867,822 Cannabinoid receptor modulators
Provided are certain methods useful in the treatment of pain comprising administering a compound of Formula Ia and pharmaceutical compositions thereof that...
US-9,867,821 Hexahydro-1H-4,7-methanoisoindole-1,3-dione compounds
The present invention is directed to therapeutic agents which are atypical antipsychotics and which are useful in the treatment of neurological and psychiatric...
US-9,867,820 Role of N-2-hydroxy-ethyl-piperazine-N'-2-ethane sulfonic acid (HEPES) in pain control and reversal of...
Compositions and therapeutic uses of HEPES and derivatives in the treatment of pain associated with cancers and side-effects including post-chemotherapy...
US-9,867,819 Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic...
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems,...
US-9,867,818 Sublingual buprenorphine spray
The invention provides sublingual formulations containing buprenorphine, a pharmaceutically acceptable salt thereof, or a derivative thereof. The invention...
US-9,867,817 Systems and methods for treating an opioid-induced adverse pharmacodynamic response
Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient...
US-9,867,816 PPAR.gamma. agonists for treatment of multiple sclerosis
Methods of treatment of multiple sclerosis (MS) with PPAR.gamma. agonists, and in particular with the compound of formula (I) known as INT131: ##STR00001##
US-9,867,815 Pharmaceutical compositions and methods of using the same
Novel pharmaceutical compositions including cocaine hydrochloride and methods of treating patients using those pharmaceutical compositions are described.
US-9,867,814 Use of non-peptidic NK1 receptor antagonists for the production of apoptosis in tumour cells
The invention relates to the use of substance P antagonists and, in particular, the use of non-peptidic NK1 receptor antagonists for the treatment of cancer...
US-9,867,813 Aminopyridine based buffers with wide buffering ranges, antibiotics and myelin disease therapy
Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be...
US-9,867,812 N-biarylamides
The invention relates to N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of...
US-9,867,811 Method of treating atherosclerosis in high triglyceride subjects
The present invention provides a compound of Formula I: ##STR00001## for use in the treatment, amelioration and/or prevention of diseases and conditions...
US-9,867,810 Ophthalmic pharmaceutical compositions and uses relating thereto
The disclosure relates to ophthalmic pharmaceutical compositions comprising pilocarpine or a pharmaceutically acceptable salt. Aspects of the disclosure further...
US-9,867,809 Encapsulated active ingredients for controlled enteric release
A method of forming a granule having an internal three-dimensional framework of channels to control and sustain the release of an active ingredient for enteric...
US-9,867,808 Compositions and methods for non-surgical treatment of Ptosis
Provided are pharmaceutical compositions, and methods of use of the compositions, for the non-surgical treatment of ptosis (eyelid droop). In one embodiment the...
US-9,867,807 Compositions and methods for drug-sensitization or inhibition of a cancer cell
The disclosure provides rifamycin and rifamycin derivative compositions, including rifabutin and rifabutin derivative compositions able to cause ...
US-9,867,806 Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis
The present invention discloses compounds according to Formula I: ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, L, and the subscript m are as defined herein....
US-9,867,805 Gelatinase inhibitors and prodrugs
The invention provides compounds, compositions, and methods for the treatment of diseases, disorders, or conditions that are modulated by matrix...
US-9,867,804 Sodium ascorbate stimulation of elastogenesis
Embodiments provide methods for using ascorbate for the stimulation of production of elastic fibers by cells.
US-9,867,803 IRE-1.alpha. inhibitors
Compounds which directly inhibit IRE-1.alpha. activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful...
US-9,867,802 Method of treating Scedosporium spp. infection
The present invention provides a method of treatment of Scedosporium spp. infection in an animal comprising the step of administering to the infected animal an...
US-9,867,801 Amorphous solid dispersion comprising taxane, tablet comprising the same, and method for preparing the same
Provided is an amorphous solid dispersion including a taxane or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and a...
US-9,867,800 Method of quenching singlet and triplet excited states of pigments, such as porphyrin compounds, particularly...
A method of quenching excited state energy from a pigment that has been excited by absorption of light having a wavelength in the wavelength range of 290-800...
US-9,867,799 Diethyl-[6-(4-hydroxycarbamoyl-phenyl-carbamoyloxy-methyl)-naphthalen-2-yl- -methyl]-ammonium chloride for use...
The present invention relates to a method for treating muscular dystrophy which comprises administering ...
US-9,867,798 Ladostigil therapy for immunomodulation
Methods for treating individuals suffering from inflammation, specifically systemic inflammation including septic shock and inflammatory conditions affecting...
US-9,867,797 Benzonatate modified release solid tablets and capsules
A 12-hour anti-tussive modified release solid tablet or capsule is described which comprises a benzonatate adsorbate in a matrix with a sufficient amount of one...
US-9,867,796 Combination of a leucine source and an omega-3 unsaturated fatty acid source for use in the treatment of...
The present invention relates to a combination of a leucine source and at least one unsaturated fatty acid source for prophylactic or therapeutic treatment of...
US-9,867,795 Nitrated lipids and methods of making and using thereof
Described herein are nitrated lipids and methods of making and using the nitrated lipids.
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