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Patent # Description
US-9,878,012 IL-12 formulations for enhancing hematopoiesis
Provided are formulations for proteins to be injected into mammals. Specifically, formulations for recombinant IL-12 in mice and primates.
US-9,878,011 Treatment of inflammatory respiratory disease using biological solutions
Methods and therapeutic compositions for treating respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and devices for administering the...
US-9,878,010 Methods of treating metabolic disorders
Methods of treating metabolic and/or lipid disorders are provided comprising administering to a patient in need thereof a therapeutically effective amount of...
US-9,878,009 Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid...
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of...
US-9,878,008 Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid...
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of...
US-9,878,007 Syndecan peptides and polypeptides as inhibitors of vascular endothelial growth factor receptor-2 (VEGFR2) and...
Peptides derived from amino acid residues 210 to 240 of human syndecan 1 and methods of use of such peptides are described. These peptides can inhibit...
US-9,878,006 Treatment of obesity and obesity related disorders by pharmalogical targeting of Kv1.3 potassium channels
Activation of brown adipose tissue, treatment of obesity and/or treatment of obesity-related disorders in human or non-human animal subjects by administering to...
US-9,878,005 Method of promoting wound healing with hyodxia-induced mitogenic factor
We found that FIZZ1/RELM.alpha. is inducible by hypoxia in lung. The hypoxia-upregulated expression of FIZZ1/RELM.alpha. was located in the pulmonary...
US-9,878,004 Compositions and formulations for treatment of gastrointestinal tract malabsorption diseases and inflammatory...
Nutritive polypeptides are provided herein. Also provided are various other embodiments including nucleic acids encoding the polypeptides, recombinant...
US-9,878,003 Method of treating bone disorders using TSG-6
A method for inhibiting cartilage degradation comprising administering to a subject a therapeutically effective amount of a polypeptide comprising or consisting...
US-9,878,002 Compositions and methods involving endogenous retrovirus proteins
This disclosure describes methods and compositions that involve endogenous retrovirus proteins as diagnostic markers and/or therapeutic agents. The detection of...
US-9,878,001 Immunosuppressive Tat derivative polypeptides
The present specification provides immunosuppressive Tat derivative polypeptides, compositions, and methods of using such polypeptides and compositions to treat...
US-9,878,000 Mucoadhesive nanoparticle composition comprising immunosuppresant and methods of use thereof
Disclosed is a mucoadhesive nanoparticle delivery system for delivering an immunosuppressant, such as cyclosporine A, to a mucosal site for treatment of a...
US-9,877,999 Methods for treating metastatic stage prostate cancer
The invention provides methods and dosing regimens for eating metastatic stage prostate cancer in a subject using degarelix, as well as related methods of using...
US-9,877,998 Uses of hypoxia-inducible factor inhibitors
The present invention relates to treating a hematologic cancer using a Hypoxia-Inducible Factor (HIF inhibitor). The invention also relates to inducing acute...
US-9,877,997 Methods and compositions for regulating SRCA2A expression levels in myocardial infarction
The disclosure provides methods and compositions for increasing SERCA2a expression levels in a mammalian subject in need thereof. The methods comprise...
US-9,877,996 Biotechnological production of cyanophycin dipeptides
The present invention relates to a process for the enzymatic production of a dipeptide composition from a cyanophycin (CGP) or CGP-like polymer preparation by...
US-9,877,995 Fractions of whey permeate and use thereof for the prevention and therapy of type 2 diabetes and the metabolic...
Fractions of whey permeate, preferably made of sweet whey permeate and more preferably of hydrolyzed or partially hydrolyzed sweet whey permeate are provided,...
US-9,877,994 Methods and compositions for treatment of ADD/ADHD, depression, memory problems and other conditions
Disclosed herein are compositions and methods for treating a variety of mood and behavioral disorders, including attention deficit hyperactivity disorder...
US-9,877,993 Composition for cognitive and cosmetic purposes
The present invention relates to a composition containing an extract from the Polygonum minus for cognition and cosmetic purposes. The extract of Polygonum...
US-9,877,992 Water extracts of cinnamon and Radix Astragali
This invention relates to methods and compositions for providing improved insulin-sensitivity and/or enhanced insulin-like action, which leads to improved...
US-9,877,991 Reaction platform and method for making pollen based materials in combination with beeswax and uses thereof
A two stage reaction platform is provided to produce a pollen-based extract material, comprising the steps of a first stage including: opening and/or...
US-9,877,990 Compositions and methods for the treatment of wounds, disorders, and diseases of the skin
The present disclosure relates, in part, to pharmaceutical compositions comprising one or more polynucleotides suitable for enhancing, increasing, augmenting,...
US-9,877,989 Use of preparations comprising exosomes derived from mesenchymal stem cells (MSCs) in the prevention and...
The present invention relates to the use of exosome-preparations derived from neonatal or adult tissue-derived mesenchymal stem-cells (MSCs) for the prevention...
US-9,877,988 Method of treating lysosomal storage diseases using nucleases and a transgene
Nucleases and methods of using these nucleases for inserting a sequence encoding a therapeutic protein such as an enzyme into a cell, thereby providing proteins...
US-9,877,987 Orally administered adsorbent, therapeutic agent for renal disease, and therapeutic agent for liver disease
An object of the present invention is to provide spherical activated carbon exhibiting excellent adsorption ability for uremic substances in the body, and...
US-9,877,986 Portable, nitric oxide generator
An apparatus for portable delivery of nitric oxide without the need for pressurized tanks, power supplies, or other devices provides a single therapy session by...
US-9,877,985 Application of maltotriose-coated 4th generation polypropyleneimine dendrimer PPI-G4-OS-MAL-III
The application of maltotriose-coated 4th generation polypropyleneimine dendrimer PPI-G4-OS-Mal-III containing 25-45% of peripheral amines groups coated with...
US-9,877,984 Controllably degradable compositions and methods
Methods for treating, adhering, or sealing biological tissue are provided. The methods include combining solutions containing a polymer component and a...
US-9,877,983 Use of alginate oligomers in combating biofilms
The invention provides a method for combating biofilm, said method comprising contacting a biofilm with an alginate oligomer. The biofilm may be on an animate...
US-9,877,982 Immunoassay of S-adenosylmethionine using analogs thereof and personalized therapeutics
A method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine...
US-9,877,981 NAD biosynthesis and precursors for the treatment and prevention of cancer and proliferation
Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the...
US-9,877,980 Method and composition for treatment or prevention of type 2 diabetes and hyperlipidemia
The present invention provides a method of treating or preventing type 2 diabetes and hyperlipidemia in a subject in need thereof, comprising administrating to...
US-9,877,979 Method of treating neurological conditions with oleandrin
A method of treating neurological condition in a subject by administration of a cardiac glycoside is provided. Alzheimer's disease, Huntington's disease or...
US-9,877,978 Compositions comprising NDGA derivatives and sorafenib and their use in treatment of cancer
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and...
US-9,877,977 Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain...
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
US-9,877,976 Methods and compositions for protection of cells and tissues from computed tomography radiation
Described are methods for preventing or inhibiting genomic instability and in cells affected by diagnostic radiology procedures employing ionizing radiation....
US-9,877,975 Agent for treating meibomian gland dysfunction
The present invention aims to provide an agent for treating meibomian gland dysfunction. The present invention provides an agent for treating meibomian gland...
US-9,877,974 Topical formulations comprising a steroid
The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are...
US-9,877,973 Intraocular drug delivery device and associated methods
An intraocular active agent delivery device can include an active agent homogenously combined with a biodegradable active agent matrix such that the entire...
US-9,877,972 Treatment methods using pharmaceutical solid state forms
The invention provides and describes solid state 17.alpha.-ethynyl-androst-5-ene-3.beta., 7.beta.,17.beta.-triol including amorphous and crystalline forms and...
US-9,877,971 Soft lozenges comprising corticosteroids
Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising non-systemic corticosteroid soft lozenges,...
US-9,877,970 Therapeutic compounds and uses thereof
Described herein are compounds of Formula (I) or Formula (VI), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided...
US-9,877,969 Treatments with triazines
The invention relates to improved methods for protecting non-human animals with triazine compounds by intramuscular or subcutaneous injection(s). The invention...
US-9,877,968 6-amino-purin-8-one compounds
Compounds of formula (I): ##STR00001## wherein R.sup.1 is C.sub.1-6alkylamino, C.sub.1-6alkoxy, or C.sub.3-7cycloalkyloxy; m is an integer having a value of 3...
US-9,877,967 Methods and pharmaceutical compositions for preventing and treating renal impairment
The present invention relates to methods for treating and preventing renal impairment by administering to a subject a therapeutically effective amount of an...
US-9,877,966 Combination therapy for the inhibition of metastasis and tumorigenesis
The invention provides therapeutic compositions and methods for the inhibition of metastasis and for treatment of cancers in human and non-human mammals that...
US-9,877,965 Vitamin receptor drug delivery conjugates for treating inflammation
Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing...
US-9,877,964 Methods and compositions for treating dry eye disease and other eye disorders
The present invention relates to a method for treating a dry eye syndrome using an alpha 2 adrenergic agonist, pharmaceutically acceptable salt thereof or a...
US-9,877,963 GlyT1 inhibitors for use in the treatment of hematological disorders
The invention is related to compounds, which are GlyT1 inhibitors, for use in the treatment of hematological disorders, in particular for use in the treatment...
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