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Patent # Description
US-9,877,962 Piperazinyl derivatives for the treatment of cancer
Piperazinyl derivatives of formula (I) and their use as a drug, particularly for the treatment of cancer, are disclosed. Also disclosed are pharmaceutical...
US-9,877,961 Anticoagulant reversal agents
Novel anticoagulant reversal compounds are disclosed, as well as methods of making the compounds, pharmaceutical compositions including the compounds, methods...
US-9,877,960 Learning and memory improver
The present invention aims to provide antidementia agents which are free from the problem of side effects and are excellent in safety. The present invention...
US-9,877,959 Pharmaceutical composition containing palonosetron
Provided are a pharmaceutical composition with improved stability including palonosetron, a preparation method thereof, and a pharmaceutical package including...
US-9,877,958 Apoptosis-induced agents for the treatment of cancer and immune and autoimmune diseases
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases...
US-9,877,957 Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2
The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are inhibitors...
US-9,877,956 Antiviral compounds and methods of use thereof
Inhibitors of retroviral propagation, methods of treatment and prevention of retroviral infections using the inhibitors, and pharmaceutical compositions...
US-9,877,955 Compositions and methods for treating diseases of the nail
Methods and compositions for treating disorders of the nail and nail bed. Such compositions contain a vehicle in which all components of the composition are...
US-9,877,954 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group
The present invention relates to 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group of general formula (I) as described and...
US-9,877,953 Rifaximin
Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to...
US-9,877,952 Methods for dosing an orally active 1,2,4-oxadiazole for nonsense mutation suppression therapy
The present invention relates to specific doses of and dosing regimens for using a 1,2,4-oxadiazole benzoic acid compound in treating or preventing diseases...
US-9,877,951 Method for treating dementia
Methods are disclosed for treating dementia, including mild cognitive impairment, via administration of D-cycloserine, or a prodrug thereof, on a...
US-9,877,950 Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
This invention relates to topical compositions for combating ectoparasites and endoparasites in animals, comprising at least one isoxazoline active agent and a...
US-9,877,949 Anticancer treatment methods involving analogs and derivatives of 3-(2-substituted-ethyl) indole compounds
Methods for inhibiting cancer cell proliferation and killing cancer cells are disclosed. Such methods comprise treating cancer cells with an indole compound...
US-9,877,948 Rotigotine-containing transdermal absorption preparation with improved stability
A method for preparing a transdermal absorption composition includes mixing rotigotine and an antioxidant at a weight ratio of 1:0.0001 to 0.1. A transdermal...
US-9,877,947 C-terminal HSP90 inhibitors to treat pituitary adenomas
The present invention relates to C-terminal HSP90 inhibitors, like silibinin, novobiocin and derivatives thereof, stereoisomeric forms, prodrugs, solvates,...
US-9,877,946 Method for treating, managing, inhibiting, or preventing obesity
A composition for inducing differentiation into beige adipocytes from white adipocytes, including butein, a butein derivative, or a pharmaceutically available...
US-9,877,945 Composition preventing necrotic enteritis in galloanserans
The present invention refers to the use of a glycerol ester composition of at least one short chain fatty acid for preventing and/or alleviating necrotic...
US-9,877,944 Use of a composition comprising fish oil and juice for the treatment and/or post treatment of cancer
Disclosed is a composition including a fish oil and a juice in an oil-in-water emulsion for use in treatment and post-treatment of cancer.
US-9,877,943 Compositions and methods comprising C16:1n7-palmitoleate
One embodiment described herein is related to methods and compositions, such as nutraceutical formulations and dietary supplements, comprising ...
US-9,877,942 Co-crystals of substituted glycine and uses thereof
The present disclosure provides co-crystals of a substituted glycine compound and a co-former compound of Formula (I): ##STR00001## compositions comprising...
US-9,877,941 Treatment of nervous system disorders using combinations of RXR agonists and thyroid hormones
Disclosed herein are methods of treating disease with a combination of a RXR agonist and a thyroid hormone.
US-9,877,940 Anthraquinone compounds and their uses
The present invention relates to a compound comprising a substituted or unsubstituted anthraquinone, or a salt or isomer thereof, for use in treating a disorder...
US-9,877,939 Composition and methods for the production of S-adenosylmethionine within the body
Described herein is a method for increasing levels of S-adenosylmethionine within the human body without administering S-adenosylmethionine directly. The method...
US-9,877,938 Modified taurine, and pharmaceutical composition for preventing or treating metabolic diseases containing same
The present invention relates to a modified taurine, and a pharmaceutical composition for preventing or treating metabolic disease or a food composition, which...
US-9,877,937 Compounds and methods for treating aberrant adrenocortical cell disorders
Methods and compositions are provided for treatment of disorders associated with aberrant adrenal cortex cell behavior, including (but not limited to) treatment...
US-9,877,936 Quinone compounds for treating Ape1 mediated diseases
The invention described herein pertains to compounds and compositions for treating Ape1 mediated diseases. In particular, the invention described herein...
US-9,877,935 Parenteral dosage form of norepinephrine
The present invention relates to a ready-to-administer parenteral dosage form of norepinephrine which comprises an aqueous solution of norepinephrine, having an...
US-9,877,934 Therapy for leukemia
A pharmaceutically acceptable composition and method for leukemia therapy in a patient in need of such therapy. The composition contains, as the only active...
US-9,877,933 Method of administering amantadine prior to a sleep period
Methods of nighttime administration of amantadine to reduce sleep disturbances in patient undergoing treatment with amantadine are described, as well as...
US-9,877,932 Treatment of prostate carcinoma
Disclosed herein are naphthoquinone analogs, such as plumbagin, pharmaceutical compositions that include naphthoquinone analogs, such as plumbagin, and methods...
US-9,877,931 Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of...
The present invention relates to a polyphenol derivative of the stilbenoid family, namely trans-3,5,4'-trihydroxybibenzyl, also known as dihydro-resveratrol, as...
US-9,877,930 Topical ubiquinol oral supplement compositions with amorphous calcium phosphate
Topical, UBIQUINOL, adjunctive, supplement compositions, containing amorphous calcium phosphate fluoride (ACPF), useful in: reducing oxidative stress, relieving...
US-9,877,929 Topical vitamin D and ubiquinol oral supplement compositions
A topical vitamin D and UBIQUINOL supplement composition useful in treating oral inflammation and reducing oxidative stress comprising: a supplement mixture of...
US-9,877,928 Gear drive damper
An air damper assembly for regulating an air flow includes a frame, a plurality of elongated damper blade rotatably mounted to the frame, and a drive mechanism...
US-9,877,927 Inhibitor of odor caused by Furaneol
Provided is a substance inhibiting an odor caused by 2,5-dimethyl-4-hydroxy-3(2H)-furanone. An inhibitor of an odor caused by ...
US-9,877,926 Formulations and kits for forming bioadhesive matrices
A bioadhesive formulation, comprising gelatin, alginate and a coupling agent, capable of forming a bioadhesive matrix, which is characterized by rapid curing,...
US-9,877,925 Alcohol-resistant oral pharmaceutical form
A sustained release oral pharmaceutical form suitable for single daily dose administration has a neutral microgranule coated with a mounting layer of active...
US-9,877,924 Pharmaceutical formulation containing gelling agent
Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together...
US-9,877,923 Process for preparing therapeutic nanoparticles
The present disclosure generally relates to a process for preparing therapeutic nanoparticles, where the process includes combining a therapeutic agent with an...
US-9,877,922 Process of preparing microspheres for sustained release having improved dispersibility and syringeability
Disclosed is a process of preparing sustained release microspheres, containing a biodegradable polymer as a carrier and a drug, using spray drying. The process...
US-9,877,921 Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of...
The invention provides compositions including epinephrine nanoparticles and methods for therapeutic use of the compositions in the treatment of conditions...
US-9,877,920 Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography
The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in...
US-9,877,919 Lipid-derived neutral nanoparticles
Disclosed herein are novel lipids and liposomal compositions prepared using such compounds and related methods of neutralizing or otherwise modifying such...
US-9,877,918 Long-lasting controlled-release liposome composition and method for producing same
A liposome composition, which is obtained by mixing a water-miscible organic solution in which a phospholipid and cholesterol are contained in a total...
US-9,877,917 Liposome formulation suitable for treating or preventing tuberculosis
The invention provides liposome formulations comprising fragments from a Mycobacterium tuberculosis-complex strain. It also provides a Mycobacterium...
US-9,877,916 Methods and compositions for treating aged skin
A composition comprising an extract from damaged plant parts from the Moringaceae genus, at least one oligopeptide, at least one extract from the Laminaria...
US-9,877,915 Skin external composition for skin moisturization containing red yeast rice extract
Disclosed herein is a skin external composition containing a red yeast rice extract. More particularly, disclosed is a skin external composition containing a...
US-9,877,914 Compositions of marine botanicals to provide nutrition to aging and environmentally damaged skin
Disclosed is a topical skin composition comprising water, a first algae extract comprising Crithmum maritimum, a second algae extract comprising Ulva lactuca,...
US-9,877,913 Alkalizing delivery system for promoting an optimal oral salivary pH
An alkalizing delivery system for promoting healthier saliva is provided. The alkalizing delivery system may take many portable forms that include a saliva...
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