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Patent # Description
US-9,884,096 Compositions and methods related to graft versus host disease and treatments thereof
Embodiments of the present invention illustrate methods of treating and preventing transplantation and side effects associated with transplantation. In...
US-9,884,095 Milk-derived basic protein fraction as skin sensitivity improving agent
A skin sensitivity improving agent which is safe and, when routinely taken or applied to the skin, exerts an effect of improving deterioration in peripheral...
US-9,884,094 Method of treating diabetes mellitus
A combination comprising at least a first insulin-like compound and a second insulin-like compound for treating a condition or a disease in a subject in need...
US-9,884,093 Glucagon receptor agonists
The present invention relates to compounds with an extended duration of action at the glucagon receptor as compared to native glucagon. Specifically provided...
US-9,884,092 Methods for treating diabetes and reducing body weight
Methods for reducing body weight, altering body composition, treating diabetes, reducing HbA.sub.1c and reducing average daily blood glucose by the use of...
US-9,884,091 Treatment of neurological diseases
Methods treat neurological disorders, for example neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and stroke. Particularly although...
US-9,884,089 BPI and its congeners as radiation mitigators and radiation protectors
Described herein is a method of mitigating, in a subject (individual), tissue injury resulting from exposure to radiation (accidental/unintentional or...
US-9,884,088 TAFA4 compounds and uses thereof for treating pain
The present invention relates to a method of using a TAFA4 protein or an agonist thereof for preventing, alleviating or treating pain in a subject. In one...
US-9,884,087 Compositions and methods of improved wound healing
Compositions and methods are contemplated for treatment of a wound, and especially a sterile or TLR/NOD ligand-poor wound in which contemporaneous...
US-9,884,086 Administration method for anticancer drugs
Disclosed is a method for providing information used for comparing restoration rates of damaged DNA, wherein information about a time period when Ataxia...
US-9,884,085 Methods for the regulation of matrix metalloproteinase expression
The disclosure provides methods of reducing MMP-9 expression and/or MMP-9 activity in a mammalian subject. The disclosure also provides methods of increasing...
US-9,884,084 Bone loss preventing and bone regeneration or bone formation promoting pharmaceutical composition comprising...
The present invention relates to a bone regeneration or bone formation promoting pharmaceutical composition comprising muramyl dipeptide, an analog thereof, a...
US-9,884,083 Palm pollen for treatment of mucositis and inflammatory conditions
Compositions are provided that include date palm pollen or an extract thereof. The compositions may be formulated use in methods of treatment or prophylaxis of...
US-9,884,082 Compositions and methods for alleviating hyposalivation and for providing oral comfort
Various compositions and methods are provided to alleviate one or more symptoms associated with hyposalivation and/or xerostomia. Preferred compositions and...
US-9,884,081 Odor and smell free composition for moxibustion and method of making the same
Provided is a composition having moxibustion effects and a formulation acceptable in oriental medicine. More particularly, the composition has moxibustion...
US-9,884,080 Poxviral oncolytic vectors
The present invention relates to a poxvirus comprising a defective F4L and/or I4L gene, to composition comprising such poxvirus and to the methods and use of...
US-9,884,079 Biologically pure Lactobacillus mali strain and composition thereof for treating metabolic syndrome
A Lactobacillus mali strain that can be used for treating a metabolic syndrome is provided. A method for treating obesity, diabetes or a complication of...
US-9,884,078 Human amniotic fluid preparation having long-term stability
Methods of preparing sterile de-cellularized human amniotic fluid that is amenable for long-term storage without loss of biological functions have been...
US-9,884,077 Extract and preparation containing said extract
An extract from inflamed skins of rabbits inoculated with vaccinia virus is provided where the quality of the extract is more stabilized. A preparation, etc....
US-9,884,076 Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
The present disclosure relates generally to methods for the increased processing of tissue for the generation of cardiac stem cells, wherein the stem cells are...
US-9,884,075 Domain-swap T cell receptors
Disclosed herein are genetically engineered T cell receptors, and methods, vectors, and genetically engineered T cells related to genetically engineered T cell...
US-9,884,074 Bi-functional co-polymer use for ophthalmic and other topical and local applications
The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces....
US-9,884,072 Methods and compositions for modulating apolipoprotein (a) expression
Disclosed herein are antisense compounds and methods for decreasing apo(a) to treat, prevent, or ameliorate diseases, disorders or conditions related to apo(a)...
US-9,884,071 Compositions and methods for altering tissue specificity and improving AAV9-mediated gene transfer
A method of altering the targeting and/or cellular uptake efficiency of an adeno-associated virus (AAV) viral vector having a capsid containing an AAV9 cell...
US-9,884,070 Selective high-affinity polydentate ligands and methods of making such
This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use...
US-9,884,069 Osteoclast inhibitors for knee conditions
Oral, parenteral, and intravenous dosage forms of osteoclast inhibitors, such as neridronic acid, can be used to treat or alleviate pain or related conditions,...
US-9,884,068 Combination therapy for skin disorders
The present invention provides a novel therapeutic combination comprising one or more anti-androgen agents and one or more antibiotic/anti-inflammatory agents...
US-9,884,067 Androgen receptor down-regulating agents and uses thereof
The present disclosure provides the design and synthesis of novel steroidal compounds that cause down-regulation of the androgen receptor (AR), both full length...
US-9,884,066 Bile acid-basic amino acid conjugates and uses thereof
Compositions and methods for treating diseases or disorders associated with the metabolic syndrome using conjugates of bile acids with basic amino acids or a...
US-9,884,065 Inhibiting activity of senescent cells using a glucocorticoid
Methods are provided herein for enhancing the effectiveness of medical therapies by administering agents that suppress a biological damage response that is...
US-9,884,064 Orally disintegrating solid dosage unit containing an estetrol component
The present invention provides an orally disintegrating solid pharmaceutical dosage unit having a weight of 50-1,000 mg and containing at least 0.1 mg of an...
US-9,884,063 Amido-substituted azole compounds
The present invention relates to amido-substituted azole compounds of general formula (I), in which X.sub.1, X.sub.2, R.sup.1, R.sup.2, R.sup.4, R.sup.5,...
US-9,884,062 Salts and solid forms of (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidin- ...
Salts and solid forms of 3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,- 6-dione, or a stereoisomer thereof, are disclosed....
US-9,884,061 Injection preparation and method for producing same
Provided are an injection preparation which include: an aqueous composition containing pemetrexed or a salt thereof, at least one antioxidant agent which is...
US-9,884,060 KIF5B-RET fusion molecules and uses thereof
Novel RET fusion molecules and uses are disclosed. In one embodiment, a KIF5B-RET fusion includes an in-frame fusion of an exon of KIF5B (e.g., one or more...
US-9,884,059 Systems and methods for treating an opioid-induced adverse pharmacodynamic response
Disclosed in certain embodiments is a method of treating or preventing an opioid-induced adverse pharmacodynamic response comprising administering to a patient...
US-9,884,058 Use of Hsp70 as a regulator of enzymatic activity
The present invention concerns a method for modulating the enzymatic activity of an enzyme, wherein said enzyme interacts with BMP, said method comprising the...
US-9,884,057 Nonselective metabotropic glutamate receptor activators for treatment of attention deficit disorder and 22Q...
This application relates to methods of treating attention deficit hyperactivity disorder (ADHD), 22q deletion and/or duplication syndrome, and co-morbidities...
US-9,884,056 Oral pharmaceutical dosage forms
Controlled release oral dosage forms suitable for administration of methylphenidate are provided. Abuse-resistant controlled release oral dosage forms suitable...
US-9,884,055 Method of treating substance addictions
A pharmaceutical composition containing isomyosmine or a pharmaceutically acceptable salt thereof is administered to an individual in need thereof for treating...
US-9,884,054 Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
Described herein are methods of treating non-metastatic castrate-resistant prostate cancer with anti-androgens.
US-9,884,053 .beta.- and .gamma.-diketones and .gamma.-hydroxyketones as WNT/.beta.-catenin signaling pathway activators
The present application discloses a compound which is ##STR00001## which activates Wnt/.beta.-catenin signaling and thus treats or prevents diseases related to...
US-9,884,052 Compounds and methods to treat organophosphorus poisoning
Organophosphate (OP) nerve agents and pesticides are potent inhibitors of acetylcholinesterase (AChE). Though oxime nucleophiles can reactivate an AChE-phosphyl...
US-9,884,051 Demethylpenclomedine analogs and their use as anti-cancer agents
This disclosure concerns novel demethylpenclomedine analogs. Also disclosed are pharmaceutical compositions and methods for using such compositions to treat...
US-9,884,050 Inhibition of crystal growth of roflumilast
Roflumilast crystals have been shown to increase in size during storage. The size of the roflumilast crystals can affect the bioavailability and efficacy of a...
US-9,884,049 Microbicidal composition comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof
The present invention provides microbicidal compositions comprising an octoxynol and a quinolizidine alkaloid compound or a source thereof, and methods of using...
US-9,884,048 ERK inhibitors
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The...
US-9,884,047 Method of treating lung cancer
One example embodiment relates to a method of treating non-small cell lung cancer by administering a compound of formula (I) to a patient. Another example...
US-9,884,046 Method of treating lung cancer
One embodiment relates to a method of treating lung cancer by administering a compound of formula I to a patient. Another embodiment relates to a method of...
US-9,884,045 Transplantation adjuvant in cell therapy using neural progenitor cells
The present invention provides a transplantation adjuvant for neural progenitor cells containing valproic acid and/or zonisamide as an active ingredient.
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