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Patent # Description
US-9,889,217 Device and method for the decontamination of hollow objects such as container caps using UV radiations
A device is provided for the decontamination of hollow objects with a cavity such as caps, including: (i) a first exposure apparatus including at least a UV...
US-9,889,216 Assembly consisting of a decontamination device and at least one preform, facility and method for producing a...
The invention relates to an assembly (1) composed of at least one preform (12) and of a device (10) for decontaminating the interior of a preform (12) by...
US-9,889,215 Thermal-treatment vessel for a liquid contaminated by pathogenic agents, decontamination facility comprising...
The invention relates to a thermal-treatment vessel (17) for pathogenic liquids intended for being filled to a predetermined level leaving a compression dome,...
US-9,889,214 Removal of microorganisms from fluid samples using nanofiber filtration media
A method for removing microorganisms from liquid samples and a nanofiber containing liquid filtration medium that simultaneously exhibits high liquid...
US-9,889,213 Multimodal imaging of fibrin
Fibrin-specific imaging agents that contain at least two imaging reporters are described, as well as methods of making and using the contrast agents.
US-9,889,212 Preparation method for magnetic composite for treating and diagnosing cancer
A preparation method for a magnetic composite for treating and diagnosing cancer. The method may include a step of pyrolyzing a precursor of a magnetic...
US-9,889,211 Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically...
US-9,889,210 Exosome transfer of nucleic acids to cells
Methods for introducing nucleic acids to cells via exosomes for use in gene modulation and therapy, such as for gene silencing and to introduce genetic material...
US-9,889,209 Nanoconjugates able to cross the blood-brain barrier
The present disclosure is directed to nanoconjugates that cross the blood-brain barrier and methods of their therapeutic use.
US-9,889,208 Lipid-based drug carriers for rapid penetration through mucus linings
Mucus-penetrating liposomal nanoparticles and methods of making and using thereof are described herein. The nanoparticles contain one or more lipids, one or...
US-9,889,207 Pyrrolobenzodiazepines and conjugates thereof
A compound which is either A: ##STR00001## or B: ##STR00002## and salts and solvates thereof, as well as their conjugates with a cell-binding agent.
US-9,889,206 C-Met targeting compound-bioactive material conjugate and use thereof
Disclosed is a conjugate in which a c-Met targeting compound and a bioactive material are chemically conjugated with each other, and methods of use thereof.
US-9,889,205 Glucose-responsive insulin conjugates
Insulin conjugates comprising an insulin molecule covalently attached to at least one bi-dentate linker having two arms, each arm independently attached to a...
US-9,889,204 Polymeric antibiotics
The disclosure provides, inter alia, polymeric antibiotic compounds such as modified chitosans and methods of use thereof.
US-9,889,203 Chemical crosslinkers
Disclosed herein are methods of chemical conjugation comprising contacting a lysosomal enzyme with a first crosslinking agent to introduce aldehyde groups;...
US-9,889,202 Compounds and methods for trans-membrane delivery of molecules
A novel delivery system for drugs, and especially macromolecules such as proteins or oligonucleotides through biological membranes is provided, and specifically...
US-9,889,201 Acid-labile lipophilic prodrugs of cancer chemotherapeutic agents
The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially...
US-9,889,200 Sphingolipid-polyalkylamine-oligonucleotide compounds
Provided herein are sphingolipid-polyalkylamine phosphoramidites, methods of generating sphingolipid-polyalkylamine-oligonucleotide compounds, pharmaceutical...
US-9,889,199 PSMA ligands and uses thereof
Compounds that are PSMA ligands, pharmaceutical compositions comprising these compounds, methods for treating and detecting cancers in a subject, methods for...
US-9,889,198 Fatty acid conjugates of quetiapine, process for making and using the same
The presently described technology provides a novel class of prodrugs of quetiapine that can be synthesized by chemically conjugating fatty acids to quetiapine....
US-9,889,197 Covalently-associated diabody complexes that possess charged coil domains and that are capable of enhanced...
Diabody molecules and uses thereof in the treatment of a variety of diseases and disorders, including immunological disorders, infectious disease, intoxication...
US-9,889,196 Adjuvanted vaccines for in ovo avian vaccination
A composition includes at least one mineral oil, a surfactant having a hydrophilic property characterized by an HLB value equal to 12 and a divalent inorganic...
US-9,889,195 Immunogenic composition and uses thereof
The present invention provides an immunogenic composition comprising an antigen and a dendritic cell targeting component. A charged group is covalently attached...
US-9,889,194 Immunogenic composition for MERS coronavirus infection
Described herein are immunogenic compositions for preventing infection with Middle East respiratory syndrome coronavirus (MERS-CoV) wherein the immunogenic...
US-9,889,193 Use of a genetically modified infectious measles virus with enhanced pro-apoptotic properties (MV-deltaC virus)...
The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the...
US-9,889,192 Immunization with rabies virus vector expressing foreign protein antigen
An immune response in a subject is elicited by a regiment comprising immunization with an attenuated recombinant rabies virus encoding at least one foreign...
US-9,889,191 Peptide sequences and compositions
Provided is a polypeptide having no more than 100 amino acids, which polypeptide comprises one or more sequences having at least 60% homology with any of SEQ ID...
US-9,889,190 Dps fusion proteins for use in vaccines and diagnostics
Novel nanoparticle fusion proteins comprising proteins or peptides fused to Dps (DNA binding protein from starved cells) proteins are provided which bring forth...
US-9,889,189 Universal influenza vaccine based on heterologous multiple M2E proteins
Disclosed are universal influenza A vaccines capable of providing broader crossprotection. The vaccine contains a fusion protein comprising tandem repeats of...
US-9,889,188 Ebola virus composition/vaccine
The present invention is directed to a composition and/or plasmid and/or vector vaccine which encodes four fragments of the GP1 Ebola protein attached to the...
US-9,889,187 Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs...
US-9,889,186 Oral vaccine having improved cellular immunity induction potency
An oral preparation for the prophylaxis or treatment of a disease with infection by a pathogen, containing a killed lactic acid bacterium expressing, on the...
US-9,889,185 Method for modulating a bacterial invasion switch
The subject matter disclosed herein pertains to the modulation of a bacterial invasion switch and the subsequent use of the bacterium to vaccinate an organism....
US-9,889,184 Anti-pathogen systems
Provided is a system for protecting plants from attack by pests, including pathogens such as fungi. Specifically, a plant defensin is provided in conjunction...
US-9,889,183 PKC activators and anticoagulant in regimen for treating stroke
The present disclosure provides a method for treating stroke by administering to a subject an anticoagulant, e.g., recombinant tissue plasminogen activator...
US-9,889,182 Assisted enzyme replacement therapy
Reagents and methods useful for the synthesis of conjugates comprising guanidinylated cyclic acetals are provided. Also provided are methods for increasing the...
US-9,889,181 Bacteriophage lysin and antibiotic combinations against gram positive bacteria
The present invention provides compositions and methods for prevention, amelioration and treatment of gram positive bacteria, particularly Staphylococcal...
US-9,889,180 Method of treating cancer
The present invention relates to a pharmaceutical composition comprising a histone-lysine N-methyltransferase EZH2 (enhancer of zeste homolog 2) inhibitor and...
US-9,889,179 FGF-18 compound dosing regimen
The present invention provides a new dosing regimen for administration of FGF-18 in the treatment of a cartilage disorder, such as osteoarthritis or cartilage...
US-9,889,178 Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid...
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of...
US-9,889,177 Methods of using compositions comprising variants and fusions of FGF19 polypeptides for modulating bile acid...
The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants and fusions of fibroblast growth factor 21 (FGF21), fusions of...
US-9,889,176 Treating renal and liver dysfunction with TLR4 antagonists
The present invention derives from the finding that increased levels of Toll like receptor 4 (TLR4) is associated with liver failure and renal dysfunction...
US-9,889,175 CEACAM based antibacterial agents
Prophylactic and/or therapeutic antipathogen agents are provided that disrupt or prevent the formation of at least one homotypic and/or heterotypic...
US-9,889,174 Compositions of herbal formulations and uses thereof
Disclosed herein are herbal formulations for relief from symptoms of skin disease. The formulations can also be combined with an active or inactive ...
US-9,889,173 Composition for improving macular pigment density and preventing or treating age-related macular degeneration
The present invention provides a composition for improving macular pigment optical density and preventing or treating age-related macular optical degeneration....
US-9,889,171 Topical compositions and methods for reducing oxidative stress
A composition for the topical application on a mammalian skin comprises one or more Brassica plant extracts selected from the group consisting of: Brassica...
US-9,889,170 Synthesis of nanoparticles using Balanites aegyptiaca
A method of preparing nanoparticles from desert date can include providing a metal salt solution comprising metal ions; providing desert date extract solution...
US-9,889,169 Cancer therapy with a parvovirus combined with a Bcl-2 inhibitor
Described is a pharmaceutical composition comprising (a) a parvovirus and (b) an Bcl-2 inhibitor and the use of said composition for treatment of cancer, e.g.,...
US-9,889,168 Respiratory syncytial virus with a genomic deficiency complemented in trans
The invention relates to pneumoviral virions comprising a viral genome that has a mutation in a gene coding for a protein that is essential for infectivity of...
US-9,889,167 Lactobacillus plantarum isolated from leaves of Camellia sinensis
Disclosed are novel Lactobacillus plantarum strains as well as a composition containing the novel Lactobacillus plantarum strains or a culture thereof.
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