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Patent # | Description |
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US-9,993,519 |
Anticancer peptide for inhibiting proliferation of cancer stem cells and
use thereof The present invention relates to an anticancer composition comprising a peptide that inhibits the proliferation of cancer stem cells present in tumor tissue and... |
US-9,993,518 |
Association of a tetrapeptide and a glyceryl ester for treating androgenic
alopecia An association comprising a peptide is described containing the sequence A-Lys-Gly-His-Lys-NH.sub.2 (SEQ ID NO: 1), wherein A is the radical corresponding to a... |
US-9,993,517 |
Methods and compositions for preserving retinal ganglion cells Provided are methods and compositions for maintaining the viability of retinal ganglion cells in a subject with an ocular disorder including, for example,... |
US-9,993,516 |
Treatment of left ventricular non-compaction and dilated cardiomyopathy by
inhibiting melanocortin receptor four The present disclosure provides methods and compositions for treatment of left ventricular non-compaction and dilated cardiomyopathies. |
US-9,993,515 |
Methods of treatment using water-soluble tryptophan-containing peptides
obtained by the hydrolysis of hens eggs... The present invention relates to a process to produce a composition comprising water-soluble peptides and having a Trp/LNAA ratio of more than 0.15, which... |
US-9,993,514 |
Compounds A compound of formula (I): ##STR00001## or a pharmaceutically acceptable salt thereof, compositions, combinations and medicaments containing said compounds... |
US-9,993,513 |
Preparation made from oatmeal and method for its use A preparation is disclosed, made of, preferably colloidal, oat flour, along with the same for use in the treatment of diseases, further cosmetic methods,... |
US-9,993,512 |
Use of escin The present invention provides the use of escin for the manufacture of a pharmaceutical preparation for the treatment diseases mediated or caused by activated... |
US-9,993,511 |
Pharmaceutical compositions for treating thermal injuries and wounds
combined with bone injuries The present invention relates to a pharmaceutical composition for treating thermal injuries and wounds combined with bone injuries. More specifically, the... |
US-9,993,510 |
Acne-removing traditional chinese medicine composition and preparation
method thereof Disclosed are an acne-removing traditional Chinese medicine composition and a preparation method thereof, wherein the traditional Chinese medicine composition... |
US-9,993,509 |
Method for regulating blood glucose level A method for increasing the expression of SIRT1 mRNA and/or decreasing the expression of SOCS3 mRNA, and especially for regulating blood glucose levels in a... |
US-9,993,508 |
Composition comprising banyan tree, lotus, and clover serum fractions
(aging) The present invention relates to compositions comprising banyan tree, lotus, and clover serum fractions. A method of improving the appearance of aging skin may... |
US-9,993,507 |
Methods of improving milk production and compositional characteristics The disclosure relates to isolated microorganisms--including novel strains of the microorganisms--microbial consortia, and compositions comprising the same.... |
US-9,993,506 |
Methods for the treatment of degenerative disc diseases by human birth
tissue material composition Methods for treating degenerative disc disease by administering a human birth tissue material composition are provided. The method includes the step of... |
US-9,993,505 |
Innervation of engineered structures Methods of generating an innervated muscle structures are disclosed as well as bioengineered structures for tissue repair or regeneration. The methods can... |
US-9,993,504 |
Methods and compositions for generating chondrocyte lineage cells and/or
cartilage like tissue A method for generating chondrocytes and/or cartilage, optionally articular like non-hypertrophic chondrocyte cells and/or cartilage like tissue and/or... |
US-9,993,503 |
Methods for production of platelets from pluripotent stem cells and
compositions thereof Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are... |
US-9,993,502 |
Genetically-modified cells comprising a modified human T cell receptor
alpha constant region gene Disclosed herein is a genetically-modified cell comprising in its genome a modified human T cell receptor alpha constant region gene, wherein the cell has... |
US-9,993,500 |
Proton-binding polymers for oral administration Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical... |
US-9,993,499 |
Product for and method of protecting and increasing friction of animal
paws An adhesive and solid particulates adhered to the pads of an animal's paw, the adhesive being cured, thereby increasing the friction of the surface of the pads;... |
US-9,993,498 |
Method for the prevention and treatment of gastrointestinal distress in
horses and other species Embodiments of a method and supplement for preventing and/or treating gastrointestinal distress, including ulcer conditions, in animals are disclosed. The... |
US-9,993,497 |
Use of alginate compositions in preventing or reducing liver damage caused
by a hepatotoxic agent Disclosed herein are compositions, methods and uses utilizing alginate compositions, for treating, preventing and/or reducing liver damage induced by a... |
US-9,993,496 |
Method of administering hyaluronan formulation for supporting joint health Disclosed is a method for mitigating or ameliorating osteoarthritis in vertebrate subjects including administering to a subject a therapeutically effective... |
US-9,993,495 |
Intrapulmonary administration of polynucleotide toll-like receptor 9
agonists for treating cancer of the lung The present disclosure relates to methods for treating cancer by intrapulmonary administration of a polynucleotide Toll-like receptor 9 agonist. The methods of... |
US-9,993,494 |
Compositions and methods for treating fibrotic disease The present disclosure relates to compositions and methods for treating or preventing a fibrotic disorder or disease. |
US-9,993,493 |
Composition for prevention, amelioration or treatment of metabolic
syndrome A composition comprising (a) and (b), and a food or drink or a medicine comprising the composition, wherein (a) is at least a kind of polyphenols selected from... |
US-9,993,492 |
Lysophospholipids and lysophospholipid analogues against honeybee brood
diseases The present invention refers to a compound selected from the group consisting of a lysophospholipid and a lysophospholipid analog for use in the treatment or... |
US-9,993,491 |
Guanine riboswitch binding compounds and their use as antibiotics The present invention includes novel compounds and pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against... |
US-9,993,490 |
Phosphonic acid compounds and screening method The present invention relates to pharmaceutical compositions comprising a phosphonic acid compound, such as a natural product. Such compounds can include, such... |
US-9,993,489 |
Methods for treating solid tumor cancers using a histone deacetylase
inhibitor and an I.kappa.B kinase inhibitor Methods for the treatment of solid tumor cancers, specifically ovarian cancer and drug-resistant solid tumors, are disclosed. A method comprises administering a... |
US-9,993,488 |
Dry powder formulations for inhalation A respirable dry powder including acetylsalicylic acid in particles having a mass median aerodynamic diameter (MMAD) within a range of about 0.5 .mu.m to about... |
US-9,993,487 |
Cyclodextrin and budesonide derivative compositions and methods The present invention relates to novel and useful pharmaceutical compositions formulated with a cyclodextrin compound and a budesonide derivative for the... |
US-9,993,486 |
Oral quetiapine suspension formulations with extended shelf life and
enhanced bioavailability A quetiapine fumarate composition for oral administration is provided comprising a pharmaceutically acceptable salt or solvate of quetiapine existing as a... |
US-9,993,485 |
Highly concentrated stable meloxicam solutions for needleless injection An aqueous cyclodextrin-free solution of meloxicam suitable is provided for administration by needleless injection, containing a pharmacologically acceptable... |
US-9,993,484 |
2-(morpholin-4-yl)-1,7-naphthyridines The present invention relates to substituted 2-(morpholin-4-yl)-1,7-naphthyridine compounds of general formula (I) or (1b), to methods of preparing said... |
US-9,993,483 |
Compositions and methods for treating ophthalmic, octic, or nasal
infections The present invention relates to methods for treating an ophthalmic, otic, or nasal infection comprising treating the infected tissue with a composition... |
US-9,993,482 |
Pharmaceutical combination comprising a class III receptor tyrosine kinase
inhibitor and the alkylating... The present invention is directed to a combination comprising a class III receptor tyrosine kinase inhibitor and a compound of formula I or a pharmaceutically... |
US-9,993,481 |
Methods and compositions for the treatment of metabolic disorders The present invention is directed to a novel methods and compositions for the therapeutic intervention in hyperphenylalaninemia. More specifically, the... |
US-9,993,480 |
mTOR/JAK inhibitor combination therapy Provided herein is a combination therapy comprising an mTOR inhibitor and a JAK inhibitor. The combination therapy is useful for the treatment of a variety of... |
US-9,993,479 |
Trk-inhibiting compound The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related... |
US-9,993,478 |
1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas
as P38 MAP knase inhibitors There are provided compounds of formula (I) which are inhibitors of the family of p38 mitogen-activated protein kinase enzymes, and to their use in therapy,... |
US-9,993,477 |
Substituted imidazo[1,5-a]pyrazines as PDE9 inhibitors This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically... |
US-9,993,476 |
Substituted 5-flouro-1H-pyrazolopyridines and their use The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations... |
US-9,993,475 |
Method for treating a pulmonary hypertension condition A method for treating a pulmonary hypertension condition such as pulmonary arterial hypertension (PAH) in a subject comprises administering to the subject a... |
US-9,993,474 |
Bromocriptine formulations The present application describes pharmaceutical formulations of bromocriptine mesylate and methods of manufacturing and using such formulations. The... |
US-9,993,473 |
Crystalline forms of tyrosine kinase inhibitors and their salts The invention relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol- ... |
US-9,993,472 |
Treatment for osteoarthritis in a joint by administering a means for
inhibiting MDM2 Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic... |
US-9,993,471 |
Ophthalmic formulations of cetirizine and methods of use The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in... |
US-9,993,470 |
Combination therapy Described herein are compounds and compositions for treating glaucoma and/or reducing intraocular pressure. Compositions may comprise an isoquinoline compound... |
US-9,993,469 |
Combination therapy comprising oxazolidinone-quinolones for use in
treating bacterial infections The present invention provides a combination of at least one oxazolidinone-quinolone hybrid with at least one further antibacterial compound and the use thereof... |