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Patent # Description
US-1,000,6096 Methods for detection of anti-cytomegalovirus neutralizing antibodies
The present disclosure provides methods useful for determining levels of HCMV infection in host cells and, by extension, determining levels of neutralizing...
US-1,000,6095 Method of detecting heat-resistant fungus
A method of detecting a heat-resistant fungus, which has a step of identifying the heat-resistant fungus using the following nucleic acid (I) or (II): (I) a...
US-1,000,6094 Methods for discriminating interspecific relationships and intraspecific relationships of lactic acid bacteria...
Degenerate primers for amplifying fragments of the nucleotide sequences of mutL and dnaJ genes of a lactic acid bacterium of Lactobacillus casei group are...
US-1,000,6093 Detecting gastric neoplasm
Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting...
US-1,000,6092 Method to detect prostate cancer in a sample
The present invention provides methods to detect prostate cancer by detecting the RNA encoded by PCA3. The disclosure provides a method for determining a...
US-1,000,6091 Method for the diagnosis, prognosis and treatment of lung cancer metastasis
The present invention relates to a method for the diagnosis or the prognosis of metastasis in lung cancer which comprises determining if the c-MAF gene is...
US-1,000,6090 Method for the quantification, qualitative genetic characterization and gene expression characterization of...
In the present invention, a method for the qualitative genetic characterization and/or gene expression characterization of predetermined cells in a fluid sample...
US-1,000,6089 MCL-1 as a therapeutic target in SCFFBW7 deficient neoplasm
Some embodiments are based on the discovery that proliferative diseases (e.g., neoplastic diseases, for example, tumors or cancers) having an FBW7 mutation or...
US-1,000,6088 Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof
The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present...
US-1,000,6087 Markers for prenatal diagnosis and monitoring
Methods and kits are provided for diagnosing, monitoring, or predicting preeclaimpsia in a pregnant woman, trisomy 18 and trisomy 21 in a fetus, as well as for...
US-1,000,6086 Sample processing apparatus and method
The invention relates to a sample processing apparatus comprising a holder for a microtiter plate comprising a plurality of microwells, optical measurement unit...
US-1,000,6085 Nanostructured arrays on flexible polymer films
The present invention relates to nanocones and nanomaterials. In one embodiment, the present invention provides a method of fabricating an array of...
US-1,000,6084 Methods to reduce evaporation during elevated temperature
A method including contacting a tissue or cellular sample with a reagent including an evaporation reducing agent(s) having the general formula ...
US-1,000,6083 Nucleic acid sample preparation
The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices...
US-1,000,6082 On-slide straining by primer extension
A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an...
US-1,000,6081 End modification to prevent over-representation of fragments
The invention relates to a method of preparing a 5' and 3' modified library of template polynucleotides and also the use of the 5' and 3' modified library of...
US-1,000,6080 High-selectivity contact activation inhibitor based on infestin-4
The present invention relates to medicine, hematology, biotechnology and fundamental biological research; it can be used for diagnostic and research purposes...
US-1,000,6079 Method for establishing the anti-diabetic potential of bitter melon
A method is disclosed for determining the hypoglycemic potential of Momordica charantia (bitter melon) extracts through an in vitro test representative of the...
US-1,000,6078 Use of phospho-Akt as a biomarker of drug response
Use of phospho-Akt as a biomarker for predicting the response, such as resistance, to a compound, wherein phospho-Akt is Akt that has been phosphorylated on one...
US-1,000,6077 Compositions and cell-based methods for monitoring the activity of a Dengue Virus protease
The invention is directed to compositions, e.g., cell-based and multiplexed platforms, to screen for small molecule drugs that inhibit enzymes such as...
US-1,000,6076 Mass spectrometric diagnosis of sepsis without blood culture
The invention relates to methods and instruments for the rapid detection and rapid mass spectrometric identification of microbial infective agents in blood or...
US-1,000,6075 Automated loading mechanism for microbial detection apparatus
The present invention is directed to a method and automated loading mechanism for loading an apparatus. The apparatus of the present invention may include a...
US-1,000,6074 Automated microbial detection apparatus
A method and automated apparatus for rapid non-invasive detection of a microbial agent in a test sample is described herein. The apparatus may include one or...
US-1,000,6073 Use of Bacillus composition for increasing the amount of available sugars in animal feed
Methods are provided for assaying whether a Bacillus composition comprising at least one Bacillus strain is capable of increasing the amount of sugar available...
US-1,000,6072 Method for measuring resistance of biofilms
The present invention relates to a method for measuring the effect of a force on a film. In particular, the present invention relates to a method for measuring...
US-1,000,6071 Methods to control secretion of metabolic byproducts in algae to enhance recovery of said byproducts
Methods are provided to control the harvesting of desired metabolic byproducts from hypersaline photosynthetic algae. Methods are presented to control secretion...
US-1,000,6070 Fucosylation-deficient cells
An isolated nucleic acid encoding an FX protein having a serine at position 79, a lysine at position 90, a leucine at position 136, an arginine at position 211,...
US-1,000,6069 Engineered ketoreductase polypeptides
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme....
US-1,000,6068 Method for producing pulverulent ceramide
Disclosed herein is a pulverulent ceramide producing method that enables easily and efficiently extracting and separating ceramide from sugar beet pulp, and...
US-1,000,6067 Method for producing DHA through solid culture and liquid fermentation of Schizochytrium
The invention relates to a method for fermentation production of DHA, in particular a method for producing DHA through solid culture and liquid fermentation of...
US-1,000,6066 Modified cyanobacteria
Provided is a cyanobacterium with improved productivity of fatty acid. A method for producing a modified cyanobacterium, comprising causing loss of functions of...
US-1,000,6065 Microbial engineering for the production of fatty acids and fatty acid derivatives
Some aspects of this invention relate to methods useful for the conversion of a carbon source to a biofuel or biofuel precursor using engineered microbes. Some...
US-1,000,6064 Biosynthetic pathways, recombinant cells, and methods
This disclosure describes engineered biosynthetic pathways, recombinant cells, and methods relating to biosynthesis of esters. The recombinant cells may be...
US-1,000,6063 Recombinant Escherichia coli for producing succinate acid and application thereof
The invention relates to the field of producing succinate by E. coli fermentation. Specifically, the invention provides an engineered recombinant E. coli for...
US-1,000,6062 Methods for control of flux in metabolic pathways through enzyme relocation
Genetically manipulated cells, lysates of such cells, systems, and methods of use thereof are provided, where one or more enzymes in a pathway of interest are...
US-1,000,6061 Lyase and lyase-encoding DNA, vectors containing the DNA, and method for the asymmetric synthesis of...
The invention relates to a lyase and a lyase-encoding DNA, to vectors containing the DNA and to a method for the asymmetric synthesis of ...
US-1,000,6060 Selectivity of the production of vanilloids in a recombinant unicellular host
The present invention relates to methods for producing vanilloid compounds in a recombinant host, and in particular for converting a protocatechuic aldehyde...
US-1,000,6059 Selective microbial production of xylitol from biomass based sugar stream with enriched pentose component
The present invention utilizes yeast Candida tropicalis (NRRL 12968) for xylitol production, as an alternative and unexplored strain with high bioconversion...
US-1,000,6058 Recombinant host cells comprising phosphoketalase
The present invention is related to recombinant host cells comprising: (i) at least one deletion, mutation, and/or substitution in an endogenous gene encoding a...
US-1,000,6057 Recombinant yeast having enhanced gamma valerolactone tolerance and methods of use
The present invention relates to materials and methods for the production of ethanol. More particularly, the present invention provides genetically modified...
US-1,000,6056 Yeast having enhanced xylose fermentation ability, and use therefor
The present invention pertains to: mutant genes having a mutation such as a base substitution in the MTH1, GRR1 and/or CDC19 coding regions thereof; mutant...
US-1,000,6055 Microorganisms for producing butadiene and methods related thereto
The invention provides non-naturally occurring microbial organisms having a butadiene or crotyl alcohol pathway. The invention additionally provides methods of...
US-1,000,6054 Systems and methods for one-shot guide RNA (ogRNA) targeting of endogenous and source DNA
Engineered nucleic acids encoding genome editing system components are provided, as are engineered RNA-guided nucleases that include inserts encoded in part by...
US-1,000,6053 Use of chimeric nucleases to stimulate gene targeting
Gene targeting is a technique to introduce genetic change into one or more specific locations in the genome of a cell. For example, gene targeting can introduce...
US-1,000,6052 Laglidadg homing endonuclease cleaving the C-C chemokine receptor type-5 (CCR5) gene and uses thereof
Disclosed herein are compositions for inactivating the human CCR5 gene comprising engineered LAGLIDADG homing endonucleases (LHEs) and their derivatives,...
US-1,000,6051 Versatile genetic assembly system (VEGAS) to assemble pathways for expression
Provided are compositions and methods for use in assembling and expressing a plurality of transcription units using, in one aspect, homologous recombination in...
US-1,000,6050 Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom
The present invention provides vectors that contain and co-express in vivo or in vitro immunogenic polypeptides or antigens together with an OX40L polypeptide,...
US-1,000,6049 Hairpin mRNA elements and methods for the regulation of protein translation
The present invention provides novel mRNA elements capable of forming hairpin, double-stranded RNA structures independent of other non-coding RNAs. These mRNAs...
US-1,000,6048 Synthetic genes and genetic constructs
The present invention relates generally to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in...
US-1,000,6047 Non-silencing selectable marker genes and methods of use
Provided are nucleic acids and expression vectors having a non-silencing selectable marker gene, and methods of using the same. A subject expression vector...
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