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Patent # Description
US-1,002,2426 Fibroblast growth factor mutants having improved functional half-life and methods of their use
Mutant fibroblast growth factor (FGF) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the Fgf-1 subfamily...
US-1,002,2425 Engineered nucleic acids and methods of use thereof
Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to kill or reduce the growth of ...
US-1,002,2424 Use of gelsolin to treat infections
The invention relates to the use of gelsolin to treat infections and to monitor the treatment of infections. The invention also provides methods up-regulating...
US-1,002,2423 Microcin and uses thereof
Microcin MccPDI and bacteria harboring the mcpM gene which encodes MccPDI limit growth of and/or kill pathogenic bacteria such as pathogenic Escherichia coli...
US-1,002,2422 Peptidomimetic macrocycles
Novel peptidomimetic macrocycles and methods of using such macrocycles for the treatment of viral diseases are described.
US-1,002,2421 Treatment of primary and metastatic carcinoma
Disclosed are methods of treating a chemotherapy-resistant cancer, of treating a cholangiocarcinoma, of treating a metastatic carcinoma, and of treating a...
US-1,002,2420 Methods of synthesizing .gamma.-AApeptides, .gamma.-AApeptide building blocks, .gamma.-AApeptide libraries, and...
Embodiments of the present disclosure provide for .gamma.-AApeptides, .gamma.-AApeptide building blocks, methods of making .gamma.-AApeptides and libraries of...
US-1,002,2419 Methods for treating spinal cord injury
Provided are methods for promoting axon regeneration of a Central Nervous System (CNS) neuron and promoting nerve function following injury to a CNS neuron, for...
US-1,002,2418 Compositions and methods for treating beta-amyloid related diseases
In alternative embodiments the invention provides compositions and methods for ameliorating diseases and conditions having a beta-amyloid component, including...
US-1,002,2417 Peptides and compositions thereof for improvement of glycaemic management in a mammal
A peptide having 12 to 60 amino acids and including (a) a sequence of SEQUENCE ID NO: 11, or (b) a fragment of SEQUENCE ID NO: 11 that includes the sequence of...
US-1,002,2416 Highly bioavailable, water soluble and sustained release nanoformulations hydrophobic plant derived compounds...
A highly bioavailable, water soluble, sustained release nanoformulation comprising a hydrophobic plant derived compound(s) in an emulsifier phase, and aqueous...
US-1,002,2415 External composition for skin containing an enzyme-treated saponin fraction derived from the root of Camellia...
The present invention relates to a composition comprising the saponin fraction derived from the root of camellia sinensis, and more specifically, a composition...
US-1,002,2414 Multi-carotenoids compositions and methods
A stable nutritional supplement composition for oral administration comprising, in one form, about 71% by weight, of a tomato extract containing therein at...
US-1,002,2413 Herbal supplements and methods of use thereof
In one embodiment, the present application provides an herbal supplement and method for treating bloating, constipation and/or weight gain in a human subject...
US-1,002,2412 Composition for preventing or alleviating periodontal diseases, containing, as active ingredient, mangosteen...
The present invention provides a composition for preventing, improving or treating periodontal diseases comprising extract of mangosteen. The composition of the...
US-1,002,2411 Hemostatic preparation containing an extract of golden moss
The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to an extract of a plant-based "Traditional...
US-1,002,2410 Hemostatic preparation containing an extract of golden moss
The present invention relates generally to agents and devices for promoting hemostasis and, more particularly, to an extract of a plant-based "Traditional...
US-1,002,2409 Compositions and methods for improving human health and nutrition
The present invention provides compositions and methods of promoting human health and nutrition.
US-1,002,2408 Probiotic Bifidobacterium adolescentis strains
The present invention relates to novel isolated strains of Bifidobacterium adolescentis which are capable of i) increasing the trans-epithelial electrical...
US-1,002,2407 Use of a lactobacillus rhamnosus strain for reducing weight gain and/or insulin resistance
Provided are the use of Lactobacillus rhamnosus strain CNCM I-3690 for reducing diet-induced weight gain and/or diet-induced insulin resistance, and treating...
US-1,002,2406 Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them
In alternative embodiments, the invention provides compositions, e.g., formulations, used for gastric, gastrointestinal and/or colonic treatments or lavage,...
US-1,002,2405 IL-12 immunotherapy for cancer
Compositions and methods far delivering immune modulatory molecules to result in a therapeutic effect are disclosed. The compositions and methods use stably...
US-1,002,2404 Chamber for encapsulating secreting cells
The invention relates to an encapsulating chamber for secreting cells, comprising a closed shell made of a semi-permeable membrane, said membrane comprising at...
US-1,002,2403 Methods, compositions, and kits for improving pancreatic beta cell viability and treating diseases or...
The present disclosure provides novel methods for increasing .beta.-cell viability in islets by delivering RLIP76 polypeptides or GSTA4 polypeptides, or a...
US-1,002,2402 Allogenic mesendritic vector for ovarian cancer
A method of preparing an allogenic dendritic stem cell vaccine for treating ovarian cancers is disclosed. The method comprises, (a) collecting blood sample from...
US-1,002,2401 Pharmaceutical containing dendritic cells, and method for producing same
[Problem] The purpose of the present invention is to provide a novel pharmaceutical for use in cellular immunotherapy for the prevention and/or treatment of...
US-1,002,2400 Methods of capturing tumor cells
The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention...
US-1,002,2399 Nutritional composition for providing relief from wine induced headaches
A dietary nutritional supplement that provides relief for light to moderate wine consumers who experience headaches triggered by light to moderate wine...
US-1,002,2398 Supplemented antacid formulation
A supplemented antacid formulation comprising at least one primary component and at least one supplemental component. In one embodiment, a primary component is...
US-1,002,2397 Treatment of rheumatoid arthritis using noble gas mixtures
The invention disclosed provides means of inhibiting, ameliorating, and/or treatment of rheumatoid arthritis through the use of Noble gas containing mixtures....
US-1,002,2396 Compositions and methods for treating conditions of compromised skin barrier function
Compositions and methods useful in treating dermatological disorders are described. The methods include applying to the skin a composition comprising a reactive...
US-1,002,2395 Application of maltotriose-coated 4th generation poly(propyleneimine) dendrimer PPI-G4-OS-Mal-III
The subject matter of the invention relates to the method of administering the polypropyleneimine dendrimer of the fourth generation, coated with maltotriose,...
US-1,002,2394 Antiinfective composition
The present invention relates to the use of hydroxymethyl-group-containing glycosaminoglycans, such as in particular hydroxymethyl-hyaluronic acid, for the...
US-1,002,2393 Methods for treatment or prevention of damage resulting from radiation, trauma or shock
Described herein are methods of treating a subject that has been or will be exposed to radiation, trauma or shock, the method comprising identifying a subject...
US-1,002,2392 Compositions based on methyl cyclodextrins for the treatment and/or prevention of diseases by increasing the...
The invention relates to a novel use of a pharmaceutical composition comprising at least one methyl cyclodextrin having a molar substitution (MS) degree of...
US-1,002,2391 Maintenance of platelet inhibition during antiplatelet therapy
A method for reducing or maintaining platelet inhibition in a patient by administering cangrelor prior to an invasive procedure is described. The method of this...
US-1,002,2390 Phosphoramidate derivatives of 5-fluoro-2'-deoxyuridine for use in the treatment of cancer
Phosphoramidate derivates of 5-fluoro-2'-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient...
US-1,002,2389 Prophylactic or therapeutic drug for constipation
New drugs useful in the prevention or treatment of constipation are provided, in which SGLT1 inhibiting compounds, in particular, a 4-isopropylphenyl glucitol...
US-1,002,2388 Oxidized lipids and treatment or prevention of fibrosis
The present invention is directed to methods of treating or preventing fibrosis comprising an oxidized lipid or pharmaceutical composition comprising the same.
US-1,002,2387 Aza-heteroaryl compounds as PI3K-gamma inhibitors
The present invention provides aza-heteroaryl derivatives of Formula I: ##STR00001## and pharmaceutically acceptable salts thereof, wherein X, Y, Z, A, W,...
US-1,002,2386 Tomatidine, analogs thereof, compositions comprising same, and uses for same
In one aspect, the invention relates to methods for promoting muscle hypertrophy or decreasing adiposity by providing to an animal in need thereof an effective...
US-1,002,2385 Thermo-kinetic mixing for pharmaceutical applications
Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical...
US-1,002,2384 17-hydroxyprogesterone ester-containing oral compositions and related methods
The present invention provides for bioavailable oral dosage forms containing esters of 17-hydroxyprogesterone as well as related methods. The oral dosage forms...
US-1,002,2383 Devices and methods of treating methamphetamine addiction and medical and behavioral consequences of...
A method of treating a condition of in a human patient comprising pharmacologically activating a translocator protein of 18 kDa (TSPO), wherein the condition is...
US-1,002,2382 RNA polymerase I inhibitors and uses thereof
Provided are novel compounds which are capable of inhibiting an activity of RNA polymerase I, and uses thereof in treating diseases or disorders modulated by...
US-1,002,2381 Triazine compounds as PI3 kinase and mTOR inhibitors
Compounds of formula I ##STR00001## wherein: R.sup.1 is ##STR00002## and R.sup.2, R.sup.4, and R.sup.6-9 are defined herein, and pharmaceutically...
US-1,002,2380 Treatment of solid tumours
A cell permeable iron chelator, optionally in combination with an autophagy inhibiting agent, is used for treating a solid cancer tumor in a person. A preferred...
US-1,002,2379 DPP-IV inhibitor combined with a further antidiabetic agent, tablets comprising such formulations, their use...
The present invention relates to pharmaceutical compositions comprising fixed dose combinations of a DPP-4 inhibitor drug and a partner drug, processes for the...
US-1,002,2378 Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections
Compounds, compositions, and methods of treatment and prevention of HIV infection are disclosed. The compounds are pyrrolo[2,3-b]pyridines and ...
US-1,002,2377 Method of treating hypertension
Disclosed herein are compositions and methods for the treatment of pulmonary hypertension, including pulmonary arterial hypertension. The methods include...
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