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Patent # Description
US-1,002,3913 SR-BI as a predictor of elevated high density lipoprotein and cardiovascular disease
The present invention relates to the field of single nucleotide polymorphisms (SNPs) and uses therefore as a predictor of diseases and conditions. Specifically,...
US-1,002,3912 In situ hybridization method and buffer
An improved method of in situ hybridization which relies on an improved formulation of the in situ hybridization buffer is described. In at least some...
US-1,002,3911 Methods and processes for calling bases in sequence by incorporation methods
Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in...
US-1,002,3910 Multiple tagging of individual long DNA fragments
This disclosure provides methods and compositions for tagging long fragments of a target nucleic acid for sequencing and analyzing the resulting sequence...
US-1,002,3909 Methods and kits for detection of methylation status
The present invention relates to methods and kits for the detection of 5-hydroxymethylcytosine (5hmC) and/or 5-methylcytosine (5meC). In some embodiments, the...
US-1,002,3908 Nucleic acid amplification method using allele-specific reactive primer
A method is described for detecting a target nucleic acid, in which the target nucleic acid is amplified in the presence of a proofreading DNA polymerase and an...
US-1,002,3907 High throughput detection of molecular markers based on AFLP and high through-put sequencing
The present invention relates to a high throughput method for the identification and detection of molecular markers wherein restriction fragments are generated...
US-1,002,3906 Method for constructing nucleic acid single-stranded cyclic library and reagents thereof
Provided in the present invention are a method for constructing a nucleic acid single-stranded cyclic library and reagent kit thereof. The method comprises the...
US-1,002,3905 Polymerase driven NESA
The present invention relates to a novel method for detecting a target polynucleotide having a target sequence, comprising (a) exposing the target...
US-1,002,3904 Method for detection of KRAS mutations
The present invention is based on a detection method of the 9 KRAS mutations Gly12Ser, Gly12Arg, Gly12Cys, Gly12Asp, Gly12Ala, Gly12Val, Gly13Asp, Gln61His and...
US-1,002,3903 Saliva collection, processing, stabilization, and storage method
Provided herein is an all-in-one saliva collection apparatus that collects saliva to allow for the filtration of saliva in order to separate saliva components,...
US-1,002,3902 Methods for detecting enzyme activity using fluorescence lifetime imaging
Disclosed are methods of detecting enzymatic activity on a fluorophore-labeled substrate using by monitoring the fluorescence lifetime of the fluorophore.
US-1,002,3901 Characterization of lysosomal enzymes by capillary zone electrophoresis
The present invention provides, among other things, methods for the characterization of recombinant Heparan N-Sulfatase (HNS) during manufacture. The present...
US-1,002,3900 Method for quantification of allergens
The invention relates to method for quantification of the absolute amount of allergen in an allergen sample comprising: a) providing a known amount of one or...
US-1,002,3899 Composition from lobster hemocyte extracts for detection of lipopolysaccharides, peptidoglycans and...
The present invention relates to the pharmaceutics, biotechnological and chemical, and particularly to a process for preparing a composition for detecting and...
US-1,002,3898 Method for detecting Escherichia coli in a sample
A method of detecting Listeria monocytogenes. The method comprises providing a culture device with a selective culture medium and a detection article comprising...
US-1,002,3897 Biosensor chip, and biosensor device equipped with same
A biosensor chip is placed in a biosensor device and is rotated while a biochemical analysis specimen is measured, the biosensor chip comprising a main body, a...
US-1,002,3896 Cushioning device inspection system, a sampling device for inspection of a cushioning device and a cushioning...
A system for checking interior air contamination, the system including a sealed device including twin ports, a sampling device including a pump to extract at...
US-1,002,3895 Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing
A system for automated microorganism identification and antibiotic susceptibility testing comprising a reagent cartridge, a reagent stage, a cassette, a...
US-1,002,3894 Galactose-alpha-1, 3-galactose-containing n-glycans in glycoprotein products derived from CHO cells
Methods of producing recombinant therapeutic fusion proteins described herein can include culturing Chinese hamster ovary (CHO) cells under conditions suitable...
US-1,002,3893 Compositions and methods for making selenocysteine containing polypeptides
Non-naturally occurring tRNA.sup.Sec and methods of using them for recombinant expression of proteins engineered to include one or more selenocysteine residues...
US-1,002,3892 Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
The present disclosure relates to glycoproteins, particularly monoclonal antibodies, comprising a glycoengineered Fc region, wherein said Fc region comprises an...
US-1,002,3891 Process of chiral resolution of cyclic and acyclic acetates to enantiomerically pure (R)-alcohols
The patent discloses herein a process for the chiral resolution of racemic cyclic and acyclic acetates to obtain (R)-alcohol. Further, it discloses the...
US-1,002,3890 Genetically modified cell and process for use of said cell
The present invention relates to the field of biotransformation of furanic compounds. More particular the present invention relates to novel genetically...
US-1,002,3889 Microbial approach for the production of 5-hydroxytryptophan
5-hydroxytryptophan (5-HTP), a precursor of serotonin, is produced in a microbial host cell. A modified bacterial phenylalanine 4-hydroxylase (P4H) catalyzes...
US-1,002,3888 Microorganism for producing L-glutamine and method for producing L-glutamine using same
Provided are a Corynebacterium glutamicum mutant that is resistant to high concentrations of L-glutamine, and a method of producing L-glutamine by using the...
US-1,002,3887 Method of manufacturing an amino-acid composition using animal by-products
The present disclosure provides a method for preparing an amino acid composition using an animal byproduct, particularly a method for obtaining an amino acid...
US-1,002,3886 (R)-selective amination
The present invention relates to a method for the enzymatic synthesis of enantiomerically enriched (R)-amines of general formula [1][c] ##STR00001## from the...
US-1,002,3885 Process for the preparation of pregabalin
The present invention provides an improved process for the preparation of a compound of formula (I), which comprises the steps of: formula (I), (a) reacting...
US-1,002,3884 Microorganism producing docosahexaenoic acid and utilization thereof
According to the present invention, a microorganism belonging to the genus Aurantiochytrium having an 18S rRNA gene consisting of the base sequence represented...
US-1,002,3883 Method for treating sugar solution, hydrogenated sugar solution, method for producing organic compound, and...
Provided are a method for treating a saccharide solution, which comprises subjecting a saccharide solution containing at least one selected from the group...
US-1,002,3882 Hetero-oligomers of (S)-carbonyl reductases and their applications in catalyzing reduction of polyphenyl ketones
Provided are novel hetero-oligomers of (S)-carbonyl reductases and their application in catalyzing the reduction of polyphenyl ketones. Also provided are...
US-1,002,3881 Detoxifying pre-treated lignocellulose-containing materials
The invention relates to a process of detoxifying pre-treated lignocellulose-containing material comprising subjecting the pre-treated lignocellulose-containing...
US-1,002,3880 Methods and compositions for the activation of gamma-delta T-cells
The present invention relates generally to methods and compositions for gene therapy and immunotherapy that activate gamma delta T-cells, and in particular, can...
US-1,002,3879 Minimal volume reprogramming of mononuclear cells
The invention provides compositions and methods for reprogramming minimal volumes of mononuclear cells. In particular aspects, the invention provides methods...
US-1,002,3878 Method for the alteration of plants using CLE polypeptides/peptides
The present invention relates to altering the biomass and/or structure of a plant, in order to maximize its potential as a source of feedstock or increase its...
US-1,002,3877 PHI-4 polypeptides and methods for their use
Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal...
US-1,002,3876 Engineered pesticidal proteins
Engineered pesticidal polypeptides that are highly active against a wide range of pests and methods of making such polypeptides are disclosed. The nucleotide...
US-1,002,3875 Fungal resistant plants expressing HCP5
The present invention relates to a method of increasing resistance against fungal pathogens of the order Pucciniales, preferably the family Phacopsoraceae, in...
US-1,002,3874 Herbicide tolerance genes and methods of use thereof
Polypeptides and recombinant DNA molecules useful for conferring tolerance to AOPP herbicides, phenoxy acid herbicides, and pyridinyloxy acid herbicides are...
US-1,002,3873 Methods and compositions for transgenic plants with enhanced cold tolerance, ability to flower without...
The present invention provides transgenic plants having increased tolerance to cold and altered flowering characteristics. Also provided are methods and...
US-1,002,3872 Methods for producing heterologous polypeptides in mutants of trichoderma
The present invention relates to mutants of a parent Trichoderma strain, comprising a polynucleotide encoding a polypeptide and one or more genes selected from...
US-1,002,3871 Double-stranded polyC:poly(G/I) RNA for immunostimulation and cancer treatment
The present invention relates to polyC:poly(G/I) dsRNAs for triggering innate immunity, in particular through toll-like receptor 3 (TLR-3) and, optionally,...
US-1,002,3870 DNA aptamers binding the histidine tag and their application
A DNA aptamer was obtained which has an affinity for His-tag, and contains a nucleotide sequence selected from SEQ ID No. 1 and SEQ ID No. 2, which has clear...
US-1,002,3869 Bio-sensor for the detection of small molecules
This present invention provides methods for the detection of small molecules in samples comprising the steps a) coupling a nanoparticle (NP) or microparticle...
US-1,002,3868 MiRNA for treating diseases and conditions associated with neo-angiogenesis
The invention relates to the diagnostic and therapeutic uses of a miRNA molecule, an equivalent or a source thereof in a disease and condition associated with...
US-1,002,3867 Oligonucleotides for modulating gene expression and uses thereof
The present invention regards oligonucleotides for modulating the expression of a gene, in particular for modulating a gene responsible for a pathology of...
US-1,002,3866 Compositions and methods for inhibition of nucleic acids function
The invention relates generally to compositions and methods for inhibiting the function of target nucleic acids by sequence specific binding. The compositions...
US-1,002,3865 RNA-interference by single-stranded RNA molecules
The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid...
US-1,002,3864 Methods of treating a metabolic syndrome by modulating heat shock protein (HSP) 90-beta
The invention provides HSP90.beta. inhibitors comprising an antisense oligonucleotide targeting HSP90.beta., pharmaceutical compositions comprising said...
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