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Patent # Description
US-1,002,3558 Compounds
Compounds of formula (I) defined herein exhibit human neutrophil elastase inhibitory properties and are useful for the treatment of disease or conditions in...
US-1,002,3557 Therapeutic inhibitory compounds
Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting plasma...
US-1,002,3556 Androgen receptor modulators and uses thereof
Described herein are compounds that are androgen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds...
US-1,002,3555 NSAIDs derivatives and uses thereof
The present invention discloses novel compounds derived from NSAIDs and pharmaceutically acceptable salts thereof. Other aspects of the invention relate to use...
US-1,002,3554 Halogen-substituted heterocyclic compound salt
The invention provides a novel .alpha.-halogen-substituted thiophene compound salt that has a potent LPA receptor antagonistic action and is useful as a...
US-1,002,3553 Method and device for manufacturing lactide
A method and a device for manufacturing lactide, whereby crude lactide, being prepared by means of depolymerization of lactic acid oligomers, is purified by...
US-1,002,3552 Method of preparing a liquiritigenin precursor
[Problem] To provide a process suitable for mass-producing of iso-liquiritigenin. [Solution] A process for preparing iso-liquiritigenin, which comprises steps...
US-1,002,3551 Glutathione-cleavable prodrug and methods of use thereof
A glutathione-cleavable prodrug is provided herein, as well as methods for its use in treating cancer, including triple negative breast cancer. The prodrug can...
US-1,002,3550 Production of 2-substituted 4-hydroxy-4-methyltetrahydropyrans having stable odoriferous quality
The present invention relates to a method for the production of 2-substituted 4-hydroxy-4-methyltetrahydropyrans from the acid-catalyzed reaction of...
US-1,002,3549 Process for the production of 1,4-butanediol and tetrahydrofuran from furan
The present invention provides a process for the preparation of 1,4-butanediol and tetrahydrofuran said process comprising contacting furan with hydrogen and...
US-1,002,3548 Energy efficient manufacturing process for preparing N,O-triglycidyl aminophenols
The invention relates to an improved process for making monomeric triglycidyl compounds, wherein the triglycidyl compounds include N, O-triglycidyl compounds...
US-1,002,3547 Multifunctional primary amine, process for its preparation, and use thereof
The invention relates to a hydrophilically modified multifunctional amine AC which has more than one primary amino group per molecule, and at least one group...
US-1,002,3546 Acesulfame potassium compositions and processes for producing same
Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g.,...
US-1,002,3544 Heterocyclic compound
A fused heterocyclic compound having an enteropeptidase inhibitory action and use of the compound as a medicament for treatment or prophylaxis of obesity,...
US-1,002,3543 Inhibitors of lysine specific demethylase-1
The present invention relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted heterocyclic...
US-1,002,3542 Ibrutinib intermediate compounds, preparation methods and uses thereof
The present invention relates to the technical field of ibrutinib, particularly to the technical field of ibrutinib intermediate compounds and preparation...
US-1,002,3541 Urea compounds and their use as enzyme inhibitors
A compound having the following structure: ##STR00001## or a pharmaceutically acceptable salt or derivative thereof. The compound may be used in the treatment...
US-1,002,3540 Hydrogen barrier agent, hydrogen barrier film forming composition, hydrogen barrier film, method for producing...
To provide a hydrogen barrier agent capable of imparting hydrogen barrier performance to various materials; a hydrogen barrier film forming composition...
US-1,002,3539 Aryl-cyanoguanidine compounds
The present invention relates to protein-lysine N-methyltransferase SMYD2 (SET and MYND domain-containing protein 2) inhibitors, in particular SMYD2-inhibitory...
US-1,002,3538 Compounds, compositions and associated methods comprising 3-aryl quinolines
Compounds, compositions and methods useful for treating infectious diseases are provided. In particular, 3-aryl quinoline compounds, their synthesis,...
US-1,002,3537 Heterocyclic compounds for the treatment of neurological and psychological disorders
Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety...
US-1,002,3536 Suprametallogels and uses thereof
The disclosure provides nanostructures (e.g., nanospheres and nano-paddlewheels) formed through transition metal-ligand (e.g., Pd(II)-, Ni(II)-, or...
US-1,002,3535 Method for the preparation of 1-(2-halogen-ethyl)-4 piperidine-carboxylic acid ethyl esters
The present invention refers to a process for the preparation of 1-(2-halogen-ethyl)-4-piperidinecarboxylic acid ethyl esters, in particular of...
US-1,002,3534 Carbazole and tetrahydrocarbazole compounds useful as inhibitors of BTK
Disclosed are compounds of Formula (I): or a salt thereof, wherein Q is: or; and X, R.sub.1a, R.sub.1b, R.sub.3, R.sub.4, and R.sub.5 are defined herein. Also...
US-1,002,3533 Process to produce paraffinic hydrocarbon fluids from light paraffins
A process for converting light paraffins to heavier paraffinic hydrocarbon fluids is disclosed. The process involves: (1) oxidation of iso-paraffins to alkyl...
US-1,002,3532 Alkyl phenyl sulfide derivative and pest control agent
An alkyl phenyl sulfide derivative represented by the general formula [I] or an agriculturally acceptable salt thereof, and a pest control agent containing the...
US-1,002,3531 Process for preparing alkanesulfonic acids
The present invention relates to a process for preparing alkanesulfonic acids from dialkyl disulfides with nitric acid and oxygen.
US-1,002,3530 Diamine, polyamic acid, and polyimide
To provide a novel diamine, and a polyimide precursor and a polyimide using it. A diamine represented by the formula (1): ##STR00001## wherein each of X.sup.1...
US-1,002,3529 Apparatus for removing catalyst surface substances
An apparatus for efficiently removing the exuded substance and/or the attached substance on the surface of a catalyst (catalyst surface substance) from the...
US-1,002,3528 Branched 3-phenylpropionic acid derivatives and their use
The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes...
US-1,002,3527 Uncatalyzed sigmatropic rearrangement of tyrosine-based compounds
A method for producing a compound of formula (I) or a pharmaceutically acceptable salt, solvate, tautomer or stereoisomer, such as compound 1 and compound 2 is...
US-1,002,3526 Process for the preparation of lomitapide
The present invention relates to a process for preparing Lomitapide or its pharmaceutically acceptable salt thereof having high purity with acceptable levels of...
US-1,002,3525 Preparation of 18F-fluciclovine
The present invention provides a method for the production of [.sup.18F]-FACBC which has advantages over know such methods. Also provided by the present...
US-1,002,3524 Process for producing nitrobenzene
The present invention relates to a process for the continuous production of nitrobenzene by the nitration of benzene with nitric acid and sulphuric acid under...
US-1,002,3523 Systems and methods for making bioproducts
Processes for continuous preparation of bioproducts are described herein. The processes include contacting fatty acid glycerides with alcohols in the presence...
US-1,002,3522 Hydroxyalkyl acrylate and method for producing same
The hydroxyalkyl acrylate according to the present invention is characterized in that a content amount of an ester generated from acrylic acid dimer and an...
US-1,002,3521 Process and intermediates for preparing poly(anhydride-esters)
Certain embodiments of the invention provide a method comprising treating a hydroxy-carboxylic acid compound with a compound of formula (I) in the absence of a...
US-1,002,3520 Preparation of tert-butyl esters of aliphatic carboxylic acids
A process for continuously preparing the tert-butyl ester of an aliphatic C.sub.1-C.sub.4 carboxylic acid comprises: a) the reaction of an aliphatic...
US-1,002,3519 Cyclobutane containing carboxylic acid GPR120 modulators
The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as...
US-1,002,3518 Substituted aromatic compounds and related method for the treatment of fibrosis
The present invention relates to compounds of: ##STR00001## or a pharmaceutically acceptable salt thereof, wherein A is C.sub.5 alkyl, C.sub.6 alkyl, C.sub.5...
US-1,002,3517 Lactylate purification process
A method for separation of fatty acid from a mixture having fatty acid, the corresponding acyl lactylate and lactic acid, method having steps of: a) providing...
US-1,002,3516 Hydroformylation process
Catalytic metal loss when using a hydroformylation catalyst comprising an organophosphite ligand is ameliorated by adding CO to a strip gas vaporizer.
US-1,002,3515 Method for preparing cyclohexanone by hydrogenating phenol
A method of preparing cyclohexanone by hydrogenating phenol is provided. The method includes a step of introducing an additional flammable gas to dilute...
US-1,002,3514 Odorants of the violet type
The present invention relates to the use as perfuming ingredient, in particular to confer odor notes of the violet, violet leaves type, of a compound of formula...
US-1,002,3513 Telomerization methods of using ethylene and/or propylene to make telomers of limited molecular weight
The principles of the present invention are useful in telomerization reactions in which ethylene and/or propylene taxogen is used in free radical reactions to...
US-1,002,3512 Production of organic materials using oxidative hydrothermal dissolution method
Methods of producing organic materials, and in particular methods of producing petroleum materials and organic compounds such as aromatic acids, phenols, and...
US-1,002,3511 Process for the production of ethylene, vinylidene, and hydrogen chloride from ethane
A process is provided for the chlorination of ethane using chlorine as the chlorinating agent to produce vinylidene (1,1-dichloroethylene), hydrogen chloride...
US-1,002,3510 Method for producing 2,3,3,3-tetrafluoropropene
This invention provides a method for producing 2,3,3,3-tetrafluoropropene or 2-chloro-1,1,1,2-tetrafluoropropane, which is a precursor of ...
US-1,002,3509 Processes and apparatuses for production of aromatic products
Processes and apparatuses for producing a C.sub.8 aromatic isomer product are provided. The apparatus comprises an isomerization unit to provide an isomerized...
US-1,002,3508 Viscosity modifiers for decreasing the viscosity of ionic liquids
A process utilizing an ionic liquid is described. The process includes contacting a hydrocarbon feed with an ionic liquid component, the ionic liquid component...
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