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Patent # Description
US-1,002,8969 Compositions for oral administration of zoledronic acid or related compounds for treating complex regional pain...
Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,...
US-1,002,8968 Natural marine source phospholipids comprising polyunsaturated fatty acids and their applications
A phospholipid extract from a marine or aquatic biomass possesses therapeutic properties. The phospholipid extract comprises a variety of phospholipids, fatty...
US-1,002,8967 Medicament
Suggested is a medicament which is particularly useful for preventing, curing or abating of cough and inflammations of the respiratory system, comprising or...
US-1,002,8966 Aerosol pirfenidone and pyridone analog compounds and uses thereof
Disclosed herein are formulations of pirfenidone or pyridone analog compounds for aerosolization and use of such formulations for aerosol administration of...
US-1,002,8965 Use of sustained release dexamethasone in post-cataract surgery inflammation
The present embodiments provide for a treatment regimen and use of a short-term sustained release liquid formulation of dexamethasone in citrate, wherein a...
US-1,002,8964 Dry powder formulation comprising a corticosteroid and a beta-adrenergic for administration by inhalation
The invention relates to a dry powder formulation comprising corticosteroid and a beta.sub.2-adrenergic drug in combination, its process preparation, and...
US-1,002,8963 Methods for treating intrapulmonary infections
This disclosure relates to the treatment of intrapulmonary bacterial infections, including treatment of nosocomial pneumonia lung infections with pharmaceutical...
US-1,002,8962 2-amino-6-methy1-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,- 3-thiazol-4-yl amides
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have...
US-1,002,8961 Therapeutically active compounds and their methods of use
Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.
US-1,002,8960 Pyrimidine compounds as JAK kinase inhibitors
The invention provides compounds of formula (I): ##STR00001## wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt...
US-1,002,8959 Quinazolin-4 (3H)-one derivatives used as P13 kinase inhibitors
The present invention relates to the compound of formula (I) ##STR00001## and to compositions comprising the same and to the use of the compound and to...
US-1,002,8958 Methods of treating cancer with a combination of selected MEK1/2 and AXL inhibitors
Methods, compounds and kits relating to treating cancer, reducing kinase inhibitor or resistance, and reducing or preventing diminished ectodomain shedding are...
US-1,002,8957 Depot formulations
Disclosed are formulations and related methods that comprise a non-polymeric, non-water soluble high viscosity liquid carrier material having a viscosity of at...
US-1,002,8956 Methods of treating various cancers using an AXL/cMET inhibitor in combination with other agents
This application describes the use of the compound (I) or a salt thereof, either alone or in combination with other therapeutically active agents, for the...
US-1,002,8955 FGFR inhibitor for use in the treatment of hypophosphatemic disorders
The present invention relates generally to 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-ph- enylamino]-pyrimid-4-yl}-1-methyl-urea or a...
US-1,002,8954 Biheteroaryl compounds and uses thereof
The present invention provides for compounds of Formula I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases)....
US-1,002,8953 Pharmaceutical composition of rosuvastatin calcium
The invention relates to pharmaceutical compositions containing rosuvastatin calcium of formula (I) and processes for their manufacture. ##STR00001##
US-1,002,8952 Methods of treating diabetes or obesity using bile acids, bile salts, and mimics thereof
Provided herein are methods and compositions for treating metabolic diseases and conditions associated with metabolic diseases.
US-1,002,8951 Composition for reducing nervous system injury and method of making and use thereof
This application discloses a composition comprising an amiloride and/or an amiloride analog which can be used for reducing nerve injury or nervous system injury...
US-1,002,8950 Lanthionine synthetase C-like 2-based therapeutics
Provided are compounds that target the lanthionine synthetase C-like protein 2 pathway. The compounds can be used to treat a number of conditions, including...
US-1,002,8949 Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous...
US-1,002,8948 Chromone derivative as a dopamine D3 receptor antagonist for its use for the treatment of autism spectrum disorder
The present invention claims a chromone derivative and pharmaceutical compositions and combinations comprising a least the said derivative, which is a dopamine...
US-1,002,8947 Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant agent
Disclosed in certain embodiments is an oral dosage form comprising: a therapeutically effective amount of an opioid analgesic; an opioid antagonist; and an...
US-1,002,8946 Treating pain in patients with hepatic impairment
An extended release composition for an analgesic active pharmaceutical ingredient which may be an opioid, preferably hydrocodone as the only active ingredient....
US-1,002,8945 Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs and optional inhibitors thereof
A method of providing a patient with controlled release of ketone-containing opioid using a prodrug capable, upon enzymatic activation and intramolecular...
US-1,002,8944 Selective serotonin 2A/2C receptor inverse agonists as therapeutics for neurodegenerative diseases
Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in...
US-1,002,8943 Method for treatment of radiologically-dense breasts
Nitrone, nitroso, and nitroxide spintraps and spin labels and their reduction products are claimed for the treatment of dense breasts.
US-1,002,8942 3-substituted pyrazoles and uses thereof
The present invention provides for compounds of Formula (I) and various embodiments thereof, and compositions comprising compounds of Formula (I) and various...
US-1,002,8941 Composition for the management of nausea and vomiting
A pharmaceutical dosage system comprising (a) an effective amount of one or more of Doxylamine, an analog thereof, a derivative thereof, a prodrug thereof, a...
US-1,002,8940 Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders
Disclosed herein are methods of treating conditions, which may be associated with elevated levels of plasma cells and/or B-cells, with a therapeutically...
US-1,002,8939 Crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid for the treatment of disease
The present invention relates to crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid, pharmaceutical compositions and dosage forms...
US-1,002,8938 Antiviral agents and uses thereof
The present invention relates to compounds which are found to exhibit an antiviral effect. The compounds are modulators of the activity of the viral...
US-1,002,8937 Anti-viral compounds
Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds,...
US-1,002,8936 Compositions and methods employing Wolbachia FtsZ as a target for Albendazole sulfone
Compositions and Methods are described in which Albendazole sulfone binds to Wolbachia FtsZ providing anti filarial activity.
US-1,002,8935 Stabilized multi-functional antioxidant compounds and methods of use
Disclosed are novel stable compounds having anti-oxidant properties and methods of using the compounds for the treatment of diseases or injuries associated with...
US-1,002,8934 Substituted indazole derivatives active as kinase inhibitiors
The present invention relates to substituted indazole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases...
US-1,002,8933 Compositions and methods for inhibiting the growth of multi-drug resistant microbes
Compositions and methods for preventing and treating infection with multi-drug resistant bacteria with AR-13 alone or in combination with antibiotics are provided.
US-1,002,8932 Compositions and methods for improving mitochondrial function and treating neurodegenerative diseases and...
Provided are compositions comprising compounds or precursors to compounds which may be used for a variety of therapeutic applications including, for example,...
US-1,002,8931 Synergistic compositions for treating microbial infections
Synergistic pharmaceutical compositions including an RNase P inhibitor and a tRNA synthetase inhibitor are provided, as well as methods for their use in...
US-1,002,8930 Compositions capable of enhancing thermogenesis and uses thereof
The present invention refers to novel compositions and to methods of using the compositions to treat and/or prevent obesity, obesity-related diseases or...
US-1,002,8929 Method of treating raynaud's disease secondary to connectivitis using aminaphtone
The subject of the present invention is the use of aminaphtone for the preparation of a medicament for treating arteriophaties, in particular arteriophaties of...
US-1,002,8928 Compositions comprising a fatty acid oil mixture and a free fatty acid, and methods and uses thereof
Compositions comprising a fatty acid oil mixture and at least one free fatty acid, and uses thereof are disclosed. Further disclosed are preconcentrates capable...
US-1,002,8927 Topical pharmaceutical formulation
Herein described is a topical composition for application of an NSAID, the composition comprising a solution or suspension of the NSAID as active ingredient in...
US-1,002,8926 Methods of reducing risk of cardiovascular disease
Methods of lowering the plasma LDL-C levels in a patient on a stable dose of statin where the patient has an LDL-C level above treatment goal. Methods of...
US-1,002,8925 Liquid dosage forms of sodium naproxen
Described herein are oral pharmaceutical compositions comprising liquid dosage forms of sodium naproxen in soft gel capsules. In one embodiment, the...
US-1,002,8923 Biguanide compositions and methods of treating metabolic disorders
Provided herein are methods for treating certain conditions, including diabetes, obesity, and other metabolic diseases, disorders or conditions by...
US-1,002,8922 Method for enhancing folding and transport of misfolded glucocerebrosidase
Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as...
US-1,002,8921 Phytonadione compositions and related methods
Stable Phytonadione compositions for parenteral administration are provided which comprise (E) isomer of phytonadione at or greater than 97% w/w as the active...
US-1,002,8920 Methods for treating occular irritation involving tearing by administering modulators of TRPM8
The invention relates to therapeutic compositions for the treatment of dry eye, more specifically to compositions comprising a TRPM8 receptor agonist ligand....
US-1,002,8919 Lipid nanoparticle compositions and methods as carriers of cannabinoids in standardized precision-metered...
This disclosure teaches phospholipid nanoparticle compositions of cannabinoids formed from phospholipids and simpler lipids in an unfired sequential process...
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