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| Patent # | Description |
|---|---|
| US-1,002,8969 |
Compositions for oral administration of zoledronic acid or related
compounds for treating complex regional pain... Oral dosage forms of osteoclast inhibitors, such as zoledronic acid, in an acid or a salt form can be used to treat or alleviate pain or related conditions,... |
| US-1,002,8968 |
Natural marine source phospholipids comprising polyunsaturated fatty acids
and their applications A phospholipid extract from a marine or aquatic biomass possesses therapeutic properties. The phospholipid extract comprises a variety of phospholipids, fatty... |
| US-1,002,8967 |
Medicament Suggested is a medicament which is particularly useful for preventing, curing or abating of cough and inflammations of the respiratory system, comprising or... |
| US-1,002,8966 |
Aerosol pirfenidone and pyridone analog compounds and uses thereof Disclosed herein are formulations of pirfenidone or pyridone analog compounds for aerosolization and use of such formulations for aerosol administration of... |
| US-1,002,8965 |
Use of sustained release dexamethasone in post-cataract surgery
inflammation The present embodiments provide for a treatment regimen and use of a short-term sustained release liquid formulation of dexamethasone in citrate, wherein a... |
| US-1,002,8964 |
Dry powder formulation comprising a corticosteroid and a beta-adrenergic
for administration by inhalation The invention relates to a dry powder formulation comprising corticosteroid and a beta.sub.2-adrenergic drug in combination, its process preparation, and... |
| US-1,002,8963 |
Methods for treating intrapulmonary infections This disclosure relates to the treatment of intrapulmonary bacterial infections, including treatment of nosocomial pneumonia lung infections with pharmaceutical... |
| US-1,002,8962 |
2-amino-6-methy1-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl-1,-
3-thiazol-4-yl amides The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have... |
| US-1,002,8961 |
Therapeutically active compounds and their methods of use Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein. |
| US-1,002,8960 |
Pyrimidine compounds as JAK kinase inhibitors The invention provides compounds of formula (I): ##STR00001## wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt... |
| US-1,002,8959 |
Quinazolin-4 (3H)-one derivatives used as P13 kinase inhibitors The present invention relates to the compound of formula (I) ##STR00001## and to compositions comprising the same and to the use of the compound and to... |
| US-1,002,8958 |
Methods of treating cancer with a combination of selected MEK1/2 and AXL
inhibitors Methods, compounds and kits relating to treating cancer, reducing kinase inhibitor or resistance, and reducing or preventing diminished ectodomain shedding are... |
| US-1,002,8957 |
Depot formulations Disclosed are formulations and related methods that comprise a non-polymeric, non-water soluble high viscosity liquid carrier material having a viscosity of at... |
| US-1,002,8956 |
Methods of treating various cancers using an AXL/cMET inhibitor in
combination with other agents This application describes the use of the compound (I) or a salt thereof, either alone or in combination with other therapeutically active agents, for the... |
| US-1,002,8955 |
FGFR inhibitor for use in the treatment of hypophosphatemic disorders The present invention relates generally to 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-ph- enylamino]-pyrimid-4-yl}-1-methyl-urea or a... |
| US-1,002,8954 |
Biheteroaryl compounds and uses thereof The present invention provides for compounds of Formula I and embodiments and salts thereof for the treatment of diseases (e.g., neurodegenerative diseases).... |
| US-1,002,8953 |
Pharmaceutical composition of rosuvastatin calcium The invention relates to pharmaceutical compositions containing rosuvastatin calcium of formula (I) and processes for their manufacture. ##STR00001## |
| US-1,002,8952 |
Methods of treating diabetes or obesity using bile acids, bile salts, and
mimics thereof Provided herein are methods and compositions for treating metabolic diseases and conditions associated with metabolic diseases. |
| US-1,002,8951 |
Composition for reducing nervous system injury and method of making and
use thereof This application discloses a composition comprising an amiloride and/or an amiloride analog which can be used for reducing nerve injury or nervous system injury... |
| US-1,002,8950 |
Lanthionine synthetase C-like 2-based therapeutics Provided are compounds that target the lanthionine synthetase C-like protein 2 pathway. The compounds can be used to treat a number of conditions, including... |
| US-1,002,8949 |
Parenteral formulations of lipophilic pharmaceutical agents and methods
for preparing and using the same There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous... |
| US-1,002,8948 |
Chromone derivative as a dopamine D3 receptor antagonist for its use for
the treatment of autism spectrum disorder The present invention claims a chromone derivative and pharmaceutical compositions and combinations comprising a least the said derivative, which is a dopamine... |
| US-1,002,8947 |
Pharmaceutical formulation containing opioid agonist, opioid antagonist
and irritant agent Disclosed in certain embodiments is an oral dosage form comprising: a therapeutically effective amount of an opioid analgesic; an opioid antagonist; and an... |
| US-1,002,8946 |
Treating pain in patients with hepatic impairment An extended release composition for an analgesic active pharmaceutical ingredient which may be an opioid, preferably hydrocodone as the only active ingredient.... |
| US-1,002,8945 |
Compositions comprising enzyme-cleavable ketone-modified opioid prodrugs
and optional inhibitors thereof A method of providing a patient with controlled release of ketone-containing opioid using a prodrug capable, upon enzymatic activation and intramolecular... |
| US-1,002,8944 |
Selective serotonin 2A/2C receptor inverse agonists as therapeutics for
neurodegenerative diseases Behavioral pharmacological data with the compound of formula (I), a novel and selective 5HT2A/2C receptor inverse agonist, demonstrate in vivo efficacy in... |
| US-1,002,8943 |
Method for treatment of radiologically-dense breasts Nitrone, nitroso, and nitroxide spintraps and spin labels and their reduction products are claimed for the treatment of dense breasts. |
| US-1,002,8942 |
3-substituted pyrazoles and uses thereof The present invention provides for compounds of Formula (I) and various embodiments thereof, and compositions comprising compounds of Formula (I) and various... |
| US-1,002,8941 |
Composition for the management of nausea and vomiting A pharmaceutical dosage system comprising (a) an effective amount of one or more of Doxylamine, an analog thereof, a derivative thereof, a prodrug thereof, a... |
| US-1,002,8940 |
Compositions and methods for treating plasma cell disorders and B-cell
prolymphocytic disorders Disclosed herein are methods of treating conditions, which may be associated with elevated levels of plasma cells and/or B-cells, with a therapeutically... |
| US-1,002,8939 |
Crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic
acid for the treatment of disease The present invention relates to crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid, pharmaceutical compositions and dosage forms... |
| US-1,002,8938 |
Antiviral agents and uses thereof The present invention relates to compounds which are found to exhibit an antiviral effect. The compounds are modulators of the activity of the viral... |
| US-1,002,8937 |
Anti-viral compounds Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds,... |
| US-1,002,8936 |
Compositions and methods employing Wolbachia FtsZ as a target for
Albendazole sulfone Compositions and Methods are described in which Albendazole sulfone binds to Wolbachia FtsZ providing anti filarial activity. |
| US-1,002,8935 |
Stabilized multi-functional antioxidant compounds and methods of use Disclosed are novel stable compounds having anti-oxidant properties and methods of using the compounds for the treatment of diseases or injuries associated with... |
| US-1,002,8934 |
Substituted indazole derivatives active as kinase inhibitiors The present invention relates to substituted indazole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases... |
| US-1,002,8933 |
Compositions and methods for inhibiting the growth of multi-drug resistant
microbes Compositions and methods for preventing and treating infection with multi-drug resistant bacteria with AR-13 alone or in combination with antibiotics are provided. |
| US-1,002,8932 |
Compositions and methods for improving mitochondrial function and treating
neurodegenerative diseases and... Provided are compositions comprising compounds or precursors to compounds which may be used for a variety of therapeutic applications including, for example,... |
| US-1,002,8931 |
Synergistic compositions for treating microbial infections Synergistic pharmaceutical compositions including an RNase P inhibitor and a tRNA synthetase inhibitor are provided, as well as methods for their use in... |
| US-1,002,8930 |
Compositions capable of enhancing thermogenesis and uses thereof The present invention refers to novel compositions and to methods of using the compositions to treat and/or prevent obesity, obesity-related diseases or... |
| US-1,002,8929 |
Method of treating raynaud's disease secondary to connectivitis using
aminaphtone The subject of the present invention is the use of aminaphtone for the preparation of a medicament for treating arteriophaties, in particular arteriophaties of... |
| US-1,002,8928 |
Compositions comprising a fatty acid oil mixture and a free fatty acid,
and methods and uses thereof Compositions comprising a fatty acid oil mixture and at least one free fatty acid, and uses thereof are disclosed. Further disclosed are preconcentrates capable... |
| US-1,002,8927 |
Topical pharmaceutical formulation Herein described is a topical composition for application of an NSAID, the composition comprising a solution or suspension of the NSAID as active ingredient in... |
| US-1,002,8926 |
Methods of reducing risk of cardiovascular disease Methods of lowering the plasma LDL-C levels in a patient on a stable dose of statin where the patient has an LDL-C level above treatment goal. Methods of... |
| US-1,002,8925 |
Liquid dosage forms of sodium naproxen Described herein are oral pharmaceutical compositions comprising liquid dosage forms of sodium naproxen in soft gel capsules. In one embodiment, the... |
| US-1,002,8923 |
Biguanide compositions and methods of treating metabolic disorders Provided herein are methods for treating certain conditions, including diabetes, obesity, and other metabolic diseases, disorders or conditions by... |
| US-1,002,8922 |
Method for enhancing folding and transport of misfolded glucocerebrosidase Therapeutic compositions and methods for treatment of late-onset Gaucher disease are described herein. The compositions comprise compounds having activity as... |
| US-1,002,8921 |
Phytonadione compositions and related methods Stable Phytonadione compositions for parenteral administration are provided which comprise (E) isomer of phytonadione at or greater than 97% w/w as the active... |
| US-1,002,8920 |
Methods for treating occular irritation involving tearing by administering
modulators of TRPM8 The invention relates to therapeutic compositions for the treatment of dry eye, more specifically to compositions comprising a TRPM8 receptor agonist ligand.... |
| US-1,002,8919 |
Lipid nanoparticle compositions and methods as carriers of cannabinoids in
standardized precision-metered... This disclosure teaches phospholipid nanoparticle compositions of cannabinoids formed from phospholipids and simpler lipids in an unfired sequential process... |
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